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First Edition

Research Article December 6 2025
Efficacy and Safety of Marstacimab Prophylaxis in Hemophilia A/B With Inhibitors: Results from the Phase 3 BASIS Trial
Davide Matino,Suchitra Acharya,Carrie Turich Taylor,Pengling Sun,Delphine Agathon,Sangeeta Raje,Travis Gould,Andrew Palladino,Johnny Mahlangu
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Research Article December 4 2025
Belantamab mafodotin, lenalidomide and dexamethasone (BelaRd) in newly diagnosed intermediate-fit and frail myeloma
Evangelos Terpos,Maria Gavriatopoulou,Ioannis Ntanasis-Stathopoulos,Panos Malandrakis,Despina Fotiou,Nikolaos Kanellias,Magdalini Migkou, Dr,Foteini Theodorakakou,Vasiliki Spiliopoulou,Irene Solia,Evangelos Eleutherakis-Papaiakovou,Giorgos Psarros,Efstathios Kastritis,Meletios A Dimopoulos
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Research Article December 4 2025
Lipid nanotubes unmask neutrophils for complement attack
Xiaobo Liu,Yuanyuan Wang,Alexander Thomas Bauer,Alex Marki,Christian F. Krebs,Karsten Häffner,Bente Siebels,Hartmut Schlüter,Frank Hildebrand,Rebecca Halbgebauer,Markus S Huber-Lang,Klaus Ley,Matthias F Schneider,Stefan Werner Schneider,Christian Gorzelanny
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Review Article December 2 2025
How I Treat Advanced Phases of CML
Michael J. Mauro
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Research Article December 1 2025
NLRP3 inflammasome blockade treats intestinal inflammation associated with chronic granulomatous disease.
Emma Darbinian,Kodjovi D. Mlaga,Matheus Aranguren,Aléhandra Desjardins,Evelyne Martineau,Chantal Massé,Jennifer W Leiding,Johanne Poudrier,Emilia Liana Falcone
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Review Article November 25 2025
Prostaglandins in cancer revisited: principles of production, mechanisms of immune regulation, and therapeutic perspectives
Erik Müller,Bastian Kruse,Jan P Böttcher
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Review Article November 25 2025
Hemophagocytic Lymphohistiocytosis in Adults
Joanne Ino Hsu,Sarah Nikiforow,Nancy Berliner
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Letter November 25 2025
Somatic genetic rescue in ZCCHC8-associated telomere biology disorders
Sophie De Tocqueville,Flavia Donaires,Nicholas F DeCleene,Ibrahima Ba,Mina Nouri,Laëtitia Kermasson,Malika Chelbi,Emmanuel Bergot,Thierry M Leblanc,Raphael Borie,Quentin Philippot,Elise Antone,Grégoire Prevot,Elodie Blanchard,Boris Keren,Elodie Lainey,Marilia Bazzo Catto,Barbara A. Santana,Settara C. Chandrasekharappa,Frank X. Donovan,Luiz Fernando Bazzo Catto,Isabelle Callebaut,Neal S. Young,Carine Halfon-Domenech,Rodrigo T. Calado,Alison A. Bertuch,Fernanda Gutierrez-Rodrigues,Caroline Kannengiesser,Patrick Revy
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Research Article November 25 2025
Long-term Follow-up of Gastrointestinal CAR T-cell Lymphoma: Homing, Clonal Expansion, and Response to Cyclosporine
Hitomi Hosoya,Armando N Bastidas Torres,Sebastian Fernandez-Pol,John Mark Gubatan,Safa Najidh,George E Duran,Fei Dong,Zachary Ehlinger,Claire Lohman,Charles Wright, III,Bita Sahaf,Crystal L. Mackall,David B Miklos,Surbhi Sidana,David M Kurtz,Michael S Khodadoust,Lehka Mikkilineni
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Research Article November 24 2025
­IFN-γ increases δ-globin gene expression through activation of the JAK/STAT pathway in erythroid cells
Jianqiong Zhu,Kyung Chin,Jizhong Zou,Wulin Aerbajinai,Wan-Chi Lin,Hongzhen Li,Griffin P Rodgers
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Letter November 24 2025
Prior transplantation and idecabtagene vicleucel in multiple myeloma: a secondary analysis of CIBMTR data
Rahul Banerjee,Christy Khouderchah,Othman Salim Akhtar,Emily C. Liang,Jordan Gauthier,Madhav V. Dhodapkar,Andrew J. Portuguese
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Research Article November 24 2025
Multisite Validation of a Venous Thrombosis Risk Model in Critically Ill Children Through the CHAT Consortium
Julie Jaffray,Brian R Branchford,Maua Mosha Alleyne,Ernest Amankwah,E. Vincent S. Faustino,Neil A Zakai,Anthony A. Sochet,Amy Stillings,Emily Krava,Guy Young,Neil A Goldenberg
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Research Article November 24 2025
Platelet defects in patients and mice with Ehlers-Danlos syndrome
Mariia Kumskova,Gagan D Flora,Manasa K. Nayak,Ivan Budnik,Aditi Jain,Rakesh B. Patel,Abhishek B Jha,Madankumar Ghatge,Neelam Chauhan,James V. Michael,Steven E. McKenzie,Anjali Sharathkumar,Janice M Staber,Steven R Lentz,Anil Chauhan
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Research Article November 21 2025
Gene expression profiling reveals two overarching types of ALCL with distinct targetable biology: an LLMPP study
Andrew L. Feldman,Surendra Dasari,Lisa M. Rimsza,David W. Scott,Naoki Oishi,Guangzhen Hu,Pedro Farinha,Catalina Amador,Elías Campo,Wing C. Chan,James R. Cook,Jan Delabie,Kai Fu,Timothy C Greiner,Laura K Hilton,Giorgio GA Inghirami,Javeed Iqbal,Elaine S Jaffe,Ryan Morin,Sarah L. Ondrejka,German Ott,Stefania Pittaluga,Philipp W Raess,Andreas Rosenwald,Kerry J. Savage,Graham W. Slack,Susan L. Slager,Joo Y Song,George Wright,Hao-Wei Wang,Yu Zeng,Tadashi Yoshino,Xiaojun Wu,Ryan A Wilcox,xueju wang,Min Shi,Akira Satou,Anamarija M Perry,Roberto Nicolas Miranda,L.Jeffrey Jeffrey Medeiros,Matthew J Maurer,Eric Mou,Young Hyeh Ko,Kennosuke Karube,Brad S Kahl,Liuyan Jiang,David L Jaye,Alejandro Gru,Laurence L de Leval,Weina Chen,Jennifer R. Chapman,James R Cerhan,Carlos Barrionuevo,Stephen M. Ansell,Ahmed Aljudi
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Research Article November 19 2025
Outcome of children with B-cell acute lymphoblastic leukemia with hypodiploidy or BCR::ABL1 fusion undergoing allogeneic HSCT
Jochen Buechner,Ulrike Poetschger,Peter Bader,M. Akif Yeşilipek,Herbert Pichler,Julia Palma,Raquel Staciuk,Petr Riha,Gergely Kriván,Marianne Ifversen,Tayfun Güngör,Evgenios Goussetis,Krzysztof Kalwak,Jacek Toporski,Melissa Gabriel,Marleen Maria Renard,Cristina Diaz-de-Heredia,Toni Matic,Friso G. Calkoen,Peter Svec,Roland Meisel,Adriana Cristina Balduzzi,Franco Locatelli,Christina Peters,Jean-Hugues Dalle,Jerry Stein
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Research Article November 14 2025
Integrin αvβ8-mediated TGF-β1 activation regulates sustained response in immune thrombocytopenia after TPO-RA withdrawal
Heng Mei,Min Xu,Jinhui jin Shu,Lu Tang,Qinying Xie,Lili Luo,Qiuzhe Wei,Huiwen Jiang,Zhangyin Ming,Yu Hu
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Research Article November 14 2025
CPX-351 versus daunorubicin, cytarabine plus gemtuzumab ozogamicin in older adults with non-adverse risk AML: NCRI AML18
Steven Knapper,Laura W Dillon,Malavika Babu,Abin Thomas,Ian Thomas,Christopher S Hourigan,Georgia M Andrew,Richard James Dillon,Amanda Frances Gilkes,Nuria Marquez-Almuina,Sophie King,Nicholas McCarthy,Reem Bahr,Rasha W Al-Ali,Louisa Stone,Tom Coats,Jennifer L Byrne,Simone Green,Ulrik Malthe Overgaard,Rob S. Sellar,Mike Dennis,Priyanka Mehta,Robert K Hills,Sylvie D Freeman,Nigel H. Russell
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Research Article November 14 2025
Glutaredoxin 2 is essential for AML survival through mitochondrial permeability transition pore regulation
Tianyi Ling,Cristiana O'Brien,Jonathan St-Germain,Vincent Rondeau,Mary Shi,Jacob M Berman,Adrianna Kinga Cepa,Paula Saez Raez,Mark Wunderlich,Katharine Carter,Cody Stillwell,Christina R Sexton,Rachel Culp-Hill,Julie A. Reisz,Saeer A Adeel,Andy G. X. Zeng,Suraj Bansal,Emily Tsao,He Tian Tony Chen,John E. Dick,Mark D Minden,Andrea Arruda,Maria L Amaya,Anastasia N Tikhonova,Kristin Hope,Angelo D'Alessandro,Brian Raught,Courtney L Jones
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Research Article November 14 2025
Highly discriminative globin gene activation by the non-canonical BAF chromatin remodeling complex
Abhirup Bagchi,Sindhu Billakanti,Vanessa Shehu,Kathryn M. Farrell,Sarah A. Cotteta,Bailey N. Godfrey,Micaela Alpert,Jacob Flores Zeranski,Krista A. Budinich,Zhuangzhuang Geng,Osheiza Abdulmalik,Belinda M. Giardine,Cheryl A. Keller,Ross C. Hardison,Junwei Shi,Eugene Khandros
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Research Article November 12 2025
Early time to relapse as a survival prognosticator in mature T-cell/NK-cell lymphomas: results from the PETAL Consortium
Mark N Sorial,Luis Malpica,Carlos Sergio Chiattone,Edith Julia,Emmannuel Bachy,Stefan K. Barta,Robert N Stuver,Eric D. Jacobsen,Massimo Federico,Hasmukh Jain, Dr.,H. Miles Prince,Francine M Foss,Pier Luigi Zinzani,Takeshi Okatani,Won Seog Seog Kim,Estelle Verburgh,Mubarak Al-Mansour,Maria Elena Cabrera,Govind Bhagat,Devavrat Shah,Changyu Shen,Salvia Jain
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Letter November 10 2025
Utility of Peripheral Blood Testing for Detection and Surveillance of Clonal Hematopoiesis in Predisposed Individuals (CH-IPI)
Enrico Attardi,Nathan Gray,Sara Lewis,Michelle Eubanks Boals,Passant Shaker,Lili Kotmayer,Sushree S Sahoo,Peng Li,Erica F Andersen,Jian Zhao,Lucilla Pizzo,Joseph H. Oved,Rohith Jesudas,Ulrike M Reiss,Richa Sharma,Georgios E. Christakopoulos,Senthil Velan Bhoopalan,Clifford M. Takemoto,Alyssa L Kennedy,Maria Teresa Voso,Guolian Kang,Marcin W Wlodarski
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Research Article November 10 2025
Impact of TP53 mutations and their variant allele frequency in adults with newly diagnosed acute lymphoblastic leukemia
Roberta S. Azevedo,Elias Jabbour,Hagop M Kantarjian,Sravanthi Lavu,Sanam Loghavi,Nitin Jain,Koji Sasaki,Rebecca Garris,Koichi Takahashi,Farhad Ravandi,Nicholas J. Short
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Research Article November 6 2025
Engineered coagulation factor VIII with enhanced secretion and coagulation potential for hemophilia A gene therapy
Yuji Kashiwakura,Yuto Nakajima,Kio Horinaka,Tiago J.S. Lopes,Yuma Furuta,Yuki Yamaguchi,Nemekhbayar Baatartsogt,Morisada Hayakawa,Yuko Katakai,Susumu Uchiyama,Osamu Nureki,Keiji Nogami,Tsukasa Ohmori
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Research Article November 5 2025
Rapid clonal selection within early hematopoietic cell compartments presages outcome to ivosidenib combination therapy
Sven Turkalj,Felix A. Radtke,Bilyana Stoilova,Rabea Mecklenbrauck,Angus J. Groom,Niels Asger Jakobsen,Curtis A. Lachowiez,Marlen Metzner,Batchimeg Usukhbayar,Mirian Angulo Salazar,Zhihong Zeng,Sanam Loghavi,Jennifer Marvin-Peek,Verena Körber,Farhad Ravandi,Ghayas C. Issa,Tapan M. Kadia,Vasiliki Symeonidou,Anne P. de Groot,Hagop M Kantarjian,Koichi Takahashi,Marina Konopleva,Courtney D. DiNardo,Paresh Vyas
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Research Article November 5 2025
Dynamic rRNA Methylation Regulates Translation in the Hematopoietic System and is Essential for Stem Cell Fitness
Ofri Rabany,Sivan Ben Dror,Maram Arafat,Hadar Aharoni levitanus,Yudit Halperin,Virginie Marchand,Nikolai Romanovski,Noga Ussishkin,Maayan Livneh Golany,Adi Reches,Judith Wexler,Nina Mayorek,Galya Monderer-Rothkoff,Sagiv Shifman,Widad Mâmmer Bouhou,Michael VanInsberghe,Cornelius Pauli,Carsten Müller-Tidow,Ola Karmi,Yoav Livneh,Alexander van Oudenaarden,Yuri Motorin,Daphna Nachmani
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Research Article November 5 2025
Multinational Assessment of Absolute Neutrophil Counts and White Blood Cell Counts Among Healthy Duffy Null Adults
Stephen P Hibbs,Israel Chipare,Amr J. Halawani,Sophie E Legge,Geoffrey Fell,Daniel Dees,David J Roberts,Nicholas S Gleadall,Olga Shamardina,Abdulrahman A Alhamzi,Edwig Shingenge,Mohammed Jebril Alabdly,Hilary T Charuma,Mohammed A Nushaily,Judith M Sinvula,Menelik Russo,Michelle Sholzberg,Sara Paparini,Vanessa Apea,Maureen O. Achebe,Nancy Berliner,Lauren Merz
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Research Article November 5 2025
PIKfyve inhibition in myeloma disrupts autophagy and the lysosome, increasing MHC expression and cholesterol metabolism
Cecilia Bonolo De Campos,Ruijuan He,Tessa Josephine Pelino,Dor David Abelman,Zhihua Li,Daniel K C Lee,Ding Yan Wang,Michael St. Paul,Jeffrey Bruce,Craig D Simpson,Leanne Wybenga-Groot,Michael F. Moran,Rodger E Tiedemann,Trevor Pugh,Tak W. Mak,Olga Issakova,Nikolai Sepetov,Suzanne Trudel,A Keith Stewart
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Research Article November 5 2025
Guanine nucleotides drive ribosome biogenesis and glycolytic reprogramming in acute myeloid leukemia stem cells
Gentaro Kawano,Riichiro Ikeda,Daisuke Ishihara,Takahiro Shima,Teppei Sakoda,Shunsuke Yamamoto,Yu Kochi,Yuichiro Semba,Sanae Ashitani,Yasuo Mori,Koji Kato,Takahiro Maeda,Toshihiro Miyamoto,Tomoyoshi Soga,Koichi Akashi,Yoshikane Kikushige
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Research Article November 5 2025
Silencing of BCL11A by Disrupting Enhancer-Dependent Epigenetic Insulation
Kaili Wang,Juan Wang,Ruopeng Feng,Kseniia Dudnyk,Yoon Jung Jung Kim,Jun Yi Stanley Lim,Michael Lee Jr,Yuannyu Zhang,Xiaofei Gao,Yong Cheng,Stuart Orkin,Jian Zhou,Mitchell J. Weiss,Feng Yue,Jian Xu
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Review Article November 1 2025
Feasibility and Safety of Anti-PD1 First-Line Treatment of Classic Hodgkin Lymphoma: Do We See the Full Picture?
Christian Peter Jaworek,Paul J Bröckelmann
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Discussion November 1 2025
The conundrum of drug development in higher-risk MDS: Lessons learned from recently failed phase 3 clinical trials
Maximilian F. Stahl,Amer M. Zeidan
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Research Article October 29 2025
The XPO7-NPAT axis represents key vulnerabilities in TP53-mutated acute myeloid leukemia
Yuichiro Semba,Takuji Yamauchi,Daniel E. Bauer,Seishi Ogawa,Koichi Akashi,Takahiro Maeda
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Research Article October 29 2025
Brexucabtagene autoleucel for BTKi-naive relapsed/refractory mantle cell lymphoma: primary analysis of ZUMA-2 Cohort 3
Tom van Meerten,Marie José Kersten,Gloria Iacoboni,Georg R. Hess,Pim G.N.J. Mutsaers,Alejandro Martin Martin Garcia-Sancho,Andre Goy,Eva Gine,Brian T. Hill,Wen-Kai Weng,Patrick M. Reagan,Krish Patel,Ahmed Galal,Charles Herbaux,Robin Sanderson,Edouard Forcade,Max S. Topp,Roch Houot,Dan Zheng,Wangshu Zhang,Justyna Kanska,Rhine R Shen,Rita Damico Khalid,Ioana Kloos,Martin Dreyling,Michael L Wang
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Letter October 29 2025
High-grade/large B-cell lymphoma-11q has a very good prognosis in children and young people without a predisposition
Leila Ronceray,Minke Henrina Willemina Huibers,Katrin Reutter,Oussama Abla,Mara Andres,Olga Balagué,Monika Csoka,Gil Gilad,Melanie M Hagleitner,Daiki Hori,Lisa Lyngsie Hjalgrim,Janez Jazbec,Wolfram Klapper,Atsuko Nakazawa,Jaime Verdu-Amorós,Hannah von Mersi,Wilhelm Woessmann,Ana C Xavier,Birgit Burkhardt,Itziar Salaverria,Andishe Attarbaschi
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Research Article October 27 2025
Menin inhibition enhances graft-versus-leukemia effects by T-cell activation and endogenous retrovirus induction in AML
Viktor Fetsch,Lennard Frederik Schwöbel,Ezgi Ozyerli-Goknar, PhD,Anna-Verena Stell,Marco Punta,Thomas Plenge,Tabea Klaus,Manoj K. Gupta,Geoffroy Andrieux,Khalid Shoumariyeh,Sophie Pfeiffer,Eyleen Corrales,Lina Schlenke,Hosna Baniadam,Simon M. Brandl,Massimo Andreis,Michal Remen,Alina Hartmann,Kathleen Grueter,Melissa Zwick,Natalie Köhler,Monika Kuban,Eric Metzger,Christoph Rummelt,Justus Duyster,Melanie Börries,Maike Hofmann,Julian Färber,Lukas M Braun,Alexander Zähringer,Michael Lübbert,Cristina Toffalori,Luca Vago,Florian H Heidel,Susana Minguet,Petya Apostolova,Tobias Feuchtinger,Kristina Maas-Bauer,Franziska Blaeschke,Michael W.M. Kühn,Marc Timmers,Tobias Wertheimer,Florian Perner,Robert Zeiser
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Research Article October 27 2025
Multiselective RAS(ON) inhibition targets oncogenic RAS and overcomes RAS-mediated resistance to FLT3i and BCL2i in AML
Bogdan Popescu,Matthew F Jones,Madison Piao,Elaine Tran,Andrew Koh,Isabelle Lomeli,Cheryl A. C. Peretz,Natalia Murad,Sydney Abelson,Carolina E. Morales,Jose M Rivera,Alexa Rane Batingana,Jeevitha D'Souza,Yana Pikman,Michael L. Cheng,Aaron C Logan,Benjamin J. Huang,Elliot Stieglitz,Catherine C. Smith
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Research Article October 27 2025
A 3.3-Å cryo-EM structure of an engineered high-affinity human prothrombinase complex
Fatma Işık Üstok,Alexandre Faille,James A. Huntington
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Research Article October 24 2025
Age‐adapted chemotherapy and MRD‐oriented transplant for Ph-negative acute lymphoblastic leukemia: the GRAALL-2014 trial
Nicolas Boissel,Sylvie Chevret,Françoise Rigal-Huguet,Thibaut TL Leguay,Mathilde Hunault,Carlos Graux,Yves Chalandon,Eric Delabesse,Yosr Hicheri,Patrice Chevallier,Marie Balsat,Cedric Pastoret,Martine Escoffre-Barbe,Florence Pasquier,Magalie Joris,Anne Thiebaut,Anne Huynh,Nathalie Dhedin,Emilie Lemasle,Caroline Bonmati,Sebastien Maury,Gaelle Guillerm,Ana Berceanu,Urs Schanz,Thomas Cluzeau,Pascal Turlure,Philippe Rousselot,Bernard De Prijck,Nathalie Grardel,Marie-Christine Béné,Marina Lafage-Pochitaloff,Wendy Cuccuini,Norbert H Ifrah,Véronique Lheritier,Vahid Asnafi,Emmanuelle Clappier,Hervé Dombret
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Research Article October 23 2025
Therapeutic base editing to generate a gain-of-function F9 variant for hemophilia B
Nemekhbayar Baatartsogt,Yuji Kashiwakura,Takafumi Hiramoto,Rina Ito,Rikako Sato,Yasumitsu Nagao,Hina Naruoka,Haruka Takata,Morisada Hayakawa,Khishigjargal Batjargal,Tomoki Togashi,Atsushi Hoshino,Taro Shimizu,Yusuke Sato,Tatsuhiro Ishida,Osamu Nureki,Tsukasa Ohmori
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Brief Report October 21 2025
Fully Human anti-GPRC5D CAR T-Cell Therapy RD118 Induces Durable Remissions in Relapsed/Refractory Multiple Myeloma
Mengmeng Pan,Di Wang,Jie Xu,Shiwei Jin,Yan Wang,Yi Tao,Yuanfang Liu,Wanyan Ouyang,Xiangqin Weng,Hongmei Yi,Yu Huang,Xinmei Cao,Shuhua Li,Fuyuan Zhang,Weiping Zhang,Chunrui Li,Jian-Qing Mi
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Research Article October 21 2025
CPX-351 in Down syndrome-associated Myeloid Leukemia: Results and Prognostic Factors from the Phase 3 ML-DS 2018 Trial
Stephanie Laszig,Antonia Diederichs,Emilia Salzmann-Manrique,Konstantin Schuschel,José Goncalves-Dias,Hasan Issa,Milica Miladinovic,Eva Rettinger,Sibylle Wehner,Hermann Kreyenberg,Melanie Bremm,Sabine Hünecke,Helena Kerp,Katharina Waack-Buchholz,Felicitas R Thol,Bianca F Goemans,Barbara De Moerloose,Heidrun Boztug,Nastassja Keora Scheidegger,Katarzyna Pawinska-Wasikowska,Dirk Reinhardt,Jan-Henning Klusmann
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Research Article October 20 2025
The Proteostasis Network is a Therapeutic Target in Acute Myeloid Leukemia
Kentson Lam,Yoon Joon Kim,Evelyn Li-Ting Tan,Carlo Miguel Ong,Andrea Zoey Liu,Fanny Jiahua Zhou,Mary Jean Sunshine,Bernadette Chua,Silvia Vicenzi,Katelyn Zhining Chen,Helena Yu,Pierce Ford,Jie-Hua Zhou,Yuning Hong,Eric J Bennett,Leslie A Crews,Edward D. Ball,Robert Signer
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Research Article October 17 2025
Withaferin A inhibits EBV-driven lymphomagenesis through multiple mechanisms, including EBNA1 degradation
Jessica Stewart,Blossom Damania
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Review Article October 17 2025
Diagnosis and Management of AML in Pediatric Patients: Consensus Recommendations from an International Expert Panel
C. Michel Zwaan,Sarah K Tasian,Richard Aplenc,Lisa Eidenschink Brodersen,Barbara Buldini,Barbara De Moerloose,Michael N Dworzak,Linda Fogelstrand,Brenda ES Gibson,Bianca F Goemans,Henrik Hasle,Betsy A Hirsch,Gertjan JL Kaspers,Jan-Henning Klusmann,Matthew A Kutny,Thomas Lehrnbecher,Franco Locatelli,Shoeil Meshinchi,Arnaud Petit,Martina Pigazzi,Anne Tierens,E Anders Kolb,Dirk Reinhardt,Daisuke Tomizawa,Todd M Cooper
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Discussion October 17 2025
MRD intervention in AML: A new therapeutic horizon
Andrew H Wei,Harry J Iland,Courtney D. DiNardo,John Reynolds
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Review Article October 17 2025
Insights from Single-cell Omics: Cellular Heterogeneity as a Foundation of Clinical Outcome in Chronic Myeloid Leukemia
Ram Krishna Thakur,Göran Karlsson
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Review Article October 16 2025
Modulators of the Hepcidin Pathway in Polycythemia Vera and Myelofibrosis
Marina Kremyanskaya,Yelena Z Ginzburg,Ronald Hoffman
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Research Article October 16 2025
A CD22-Specific T-Cell Receptor Enables Effective Adoptive T-Cell Therapy for B-cell malignancies
Simone Rhein,Neşe Çakmak-Görür,Corinna Grunert,Sarah Hayder Jalal Al-Tabatabaee,Nazli Serin,Matthias Leisegang,Stefanos Timiliotis,Luisa Sophie Ohlmeier,Cäcilia Freund,Gerald Willimsky,Frank Konietschke,Elisa Kieback,Sarah K Tasian,Bjoern Chapuy,Ulrich Keller,Thomas Blankenstein,Antonio Pezzutto,Antonia Busse
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Research Article October 16 2025
Human missense variants in F3 impair the initiation of blood coagulation
Shabbir A Ansari,Marisa A. Brake,Nishtha Pathak,James T. Flaumenhaft,Jacob Ludington,Natasha Panwar,Ernest Turro,Sol Schulman
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Research Article October 16 2025
Ramantamig (JNJ-79635322), a novel T-cell-engaging trispecific antibody targeting BCMA, GPRC5D, and CD3, in multiple myeloma models
Kodandaram Pillarisetti,Danlin Yang,Leopoldo Luistro,Jianhong Yao,Melissa Smith,Peter Vulfson,James Testa, Jr,Randolph Ponticiello,Scott R Brodeur,Bradley Heidrich,Kathryn Packman,Sanjaya Singh,Ricardo M Attar,Yusri A Elsayed,Ulrike Philippar
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Page 1 of 3

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Efficacy and Safety of Marstacimab Prophylaxis in Hemophilia A/B With Inhibitors: Results from the Phase 3 BASIS Trial
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Lipid nanotubes unmask neutrophils for complement attack

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