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Journal Articles

Fixed-duration epcoritamab in combination with bendamustine + Rituximab (BR) for first-line (1L) treatment of follicular lymphoma (FL): 3-year results from EPCORE NHL-2 arm 3 demonstrate deep and durable responses with manageable safety

Free
Umberto Vitolo, Lorenzo Falchi, Sylvia Snauwaert, Fritz Offner, Marcel Nijland, Per-Ola Andersson, Poliana Patah, Isil Altintas, Jennifer Marek, Malene Risum, Yi Hao, Joshua Brody
Journal: Blood
Blood (2025) 146 (Supplement 1): 5357.
https://doi.org/10.1182/blood-2025-5357
Published: 2025
Journal Articles

Clinical outcomes of tisagenlecleucel in patients with relapsed/refractory follicular lymphoma (r/r FL): Phase 2 ELARA 5-year update

Free
Stephen Schuster, Catherine Thieblemont, Michael Dickinson, Joaquin Martinez-Lopez, Arne Kolstad, Jason Butler, Monalisa Ghosh, Leslie Popplewell, Julio Chavez, Emmanuel Bachy, Koji Kato, Hideo Harigae, Marie José Kersten, Charalambos Andreadis, Peter Riedell, Phoebe Joy Ho, José Antonio Pérez-Simón, Andy Chen, Loretta Nastoupil, Bastian von Tresckow, Andrés José María Ferreri, Takanori Teshima, Piers Patten, Joseph McGuirk, Fritz Offner, Andreas Viardot, Pier Luigi Zinzani, Aiesha Zia, Rakesh Awasthi, Roberto Ramos, Meryem Ktiouet Dawson, Pei Hsu, Darragh O'Donovan, Nathan Fowler, Martin Dreyling
Journal: Blood
Blood (2025) 146 (Supplement 1): 468.
https://doi.org/10.1182/blood-2025-468
Published: 2025
Journal Articles

Epcoritamab with rituximab + lenalidomide (R2) and epcoritamab maintenance deliver deep and durable remissions in previously untreated (1L) follicular lymphoma (FL): 3-year outcomes from epcore NHL-2 arms 6 and 7

Free
Lori Leslie, Gerardo Musuraca, Pau Abrisqueta, Joshua Brody, Jacob Christensen, Alexander Fosså, Marjolein Van Der Poel, Joost Vermaat, Fritz Offner, David Belada, Jian Mei, Isil Altintas, Malene Risum, Aidan Reilly, Liwei Wang, Lorenzo Falchi
Journal: Blood
Blood (2025) 146 (Supplement 1): 465.
https://doi.org/10.1182/blood-2025-465
Published: 2025
Journal Articles

Epcoritamab monotherapy demonstrates promising efficacy in patients with Richter transformation (RT): 2-year follow-up results from arm 2A of the phase 1b/2 EPCORE CLL-1 trial

Free
Arnon Kater, Ann Janssens, Herbert Eradat, Fritz Offner, Jose D. Sandoval-Sus, Mazyar Shadman, Christian Poulsen, Jacob Christensen, Meghan Thompson, Meijian Guan, Andrew J. Steele, Marcia Rios, Marie Holst Mørch, Toshihiko Oki, Rebecca Valentin, Mar Bellido, Barbara Eichhorst
Journal: Blood
Blood (2025) 146 (Supplement 1): 1017.
https://doi.org/10.1182/blood-2025-1017
Published: 2025
Journal Articles

Fixed-duration epcoritamab + R-CHOP in patients with newly diagnosed DLBCL and high IPI scores (3–5) led to sustained remissions and disease-free survival beyond 3 years: Results from the EPCORE NHL-2 trial

Free
Lorenzo Falchi, Fritz Offner, Sven de Vos, Joshua Brody, Daniel Morillo, Kim Linton, Sylvia Snauwaert, Michael Roost Clausen, Raul Cordoba, Toshihiko Oki, Monica Wielgos-Bonvallet, Mina Khoshdeli, Yi Hao, Jennifer Marek, Malene Risum, David Belada
Journal: Blood
Blood (2025) 146 (Supplement 1): 1955.
https://doi.org/10.1182/blood-2025-1955
Published: 2025
Journal Articles

Sox11-induced reprogramming of B2 cells to a B1a-like phenotype promotes Mantle Cell Lymphoma in mice

Free
Tim Pieters, Luca Pagliaro, André De Almeida, Fritz Offner, Tom Taghon, Pieter Van Vlierberghe, Steven Goossens
Journal: Blood
Blood (2025) 146 (Supplement 1): 143.
https://doi.org/10.1182/blood-2025-143
Published: 2025
Journal Articles

Final analysis of the RESONATE-2 study: up to 10 years of follow-up of first-line ibrutinib treatment for CLL/SLL

Open Access
Clinical Trials & Observations
Jan A. Burger, Paul M. Barr, Tadeusz Robak, Carolyn Owen, Alessandra Tedeschi, Anita Sarma, Piers E. M. Patten, Sebastian Grosicki, Helen McCarthy, Fritz Offner, Edith Szafer-Glusman, Cathy Zhou, Anita Szoke, Lynne Neumayr, James P. Dean, Paolo Ghia, Thomas J. Kipps
Journal: Blood
Blood (2025) 146 (18): 2168–2176.
https://doi.org/10.1182/blood.2024028205
Published: 2025
Includes: Supplemental data
Journal Articles

Englumafusp Alfa (CD19-4-1BBL) Combined with Glofitamab Is Safe and Efficacious in Patients with r/r B-NHL: Extended Follow up Analysis of the Dose-Escalation Part of Phase 1 Trial BP41072

Free
Martin Hutchings, Michael J. Dickinson, Giuseppe Gritti, Carmelo Carlo-Stella, William Townsend, Francesc Bosch, Nancy L. Bartlett, Guillaume Cartron, Herve Ghesquieres, Roch Houot, Harriet S. Walter, Fritz Offner, Natalie Dimier, Candice Jamois, Lance Smith, Sylvia Herter, Denis Sahin, Abiraj Keelara, Koorosh Korfi, Jeremy Gallien, Marie-Helene Wasmer, Heather Hinton, Matt Whayman, Isabel Prieto, Georgios Kazantzidis, Katharina Lechner, Franck Morschhauser
Journal: Blood
Blood (2024) 144 (Supplement 1): 990.
https://doi.org/10.1182/blood-2024-200096
Published: 2024
Journal Articles

Clinical Outcomes of Patients with High-Risk Relapsed/Refractory Follicular Lymphoma Treated with Tisagenlecleucel: Phase 2 ELARA 4-Year Update

Free
Catherine Thieblemont, Martin Dreyling, Michael J. Dickinson, Joaquín Martínez-Lopez, Arne Kolstad, Jason Butler, Monalisa Ghosh, Leslie L. Popplewell, Julio C. Chavez, Emmanuel Bachy, Koji Kato, Hideo Harigae, Marie José Kersten, Charalambos Andreadis, Peter A. Riedell, Phoebe Joy Ho, Jose Antonio Pérez-Simón, Andy Chen, Loretta Nastoupil, Bastian von Tresckow, Andrés José María Ferreri, Takanori Teshima, Piers E.M. Patten, Joseph P. McGuirk, Fritz Offner, Andreas Viardot, Pier Luigi Zinzani, Ram Malladi, Aiesha Zia, Rakesh Awasthi, Davide Germano, Roberto Javier Ramos, Pei Hsu, Stephen J. Schuster, Nathan H. Fowler
Journal: Blood
Blood (2024) 144 (Supplement 1): 3034.
https://doi.org/10.1182/blood-2024-201730
Published: 2024
Journal Articles

Glofitamab Induces High Response Rates and Durable Remissions in Patients (Pts) with Heavily Pretreated Relapsed/Refractory (R/R) Mantle Cell Lymphoma (MCL), Including Those with a Poor Prognosis: Subgroup Results from a Phase I/II Study

Free
Tycel J. Phillips, Marek Trněný, Carmelo Carlo-Stella, Jan Maciej Zaucha, Tomasz Wrobel, Fritz Offner, Michael J. Dickinson, Monica Tani, Michael Crump, Nancy L. Bartlett, Joaquín Martínez-Lopez, Paolo Corradini, Estefania Mulvihill, Alessia Bottos, Derrick Kaufman, James Relf, Fabiola Bene Tchaleu, Alexandra Bazeos, Linda Lundberg, Franck Morschhauser
Journal: Blood
Blood (2024) 144 (Supplement 1): 1631.
https://doi.org/10.1182/blood-2024-200018
Published: 2024
Journal Articles

Fixed-Duration Epcoritamab in Combination with Bendamustine + Rituximab for First-Line Treatment of Follicular Lymphoma: Initial Results from Epcore NHL-2 Arm 3

Free
Joshua Brody, Lorenzo Falchi, Umberto Vitolo, Marcel Nijland, Fritz Offner, Sylvia Snauwaert, Poliana Patah, Jennifer Marek, Christopher Morehouse, Andrew J. Steele, Yi Hao, Daniela Hoehn, Kim Linton
Journal: Blood
Blood (2024) 144 (Supplement 1): 1627.
https://doi.org/10.1182/blood-2024-200369
Published: 2024
Journal Articles

Epcoritamab Monotherapy in Patients (Pts) with Relapsed or Refractory (R/R) Chronic Lymphocytic Leukemia (CLL): Results from CLL Expansion and Optimization Cohorts of Epcore CLL-1

Free
Alexey Danilov, Bita Fakhri, Farrukh T. Awan, Hans Herluf Bentzen, Herbert A. Eradat, Carsten Utoft Niemann, Fritz Offner, Christian Bjørn Poulsen, Thor Hoeyer, Mar Bellido, Damien Roos Weil, Alessandra Ferrajoli, Meghan C. Thompson, Jacob Haaber Christensen, Ann Janssens, Tamar Tadmor, Mazyar Shadman, Pegah Jafarinasabian, Jimin Zhang, Marcia Rios, Alexandra Kuznetsova, Rebecca Valentin, Arnon P. Kater
Journal: Blood
Blood (2024) 144 (Supplement 1): 883.
https://doi.org/10.1182/blood-2024-199708
Published: 2024
Journal Articles

Fixed-Duration Epcoritamab + R-CHOP Induces High Complete Response Rates in Patients with Previously Untreated Diffuse Large B-Cell Lymphoma Withhigh-Risk Features: Long-Term Results from the Epcore NHL-2 Trial

Free
Lorenzo Falchi, Fritz Offner, Sven de Vos, Joshua Brody, Raul Cordoba, Kim Linton, Sylvia Snauwaert, Michael Roost Clausen, Toshihiko Oki, Andrew J. Steele, Yi Hao, Kimberly G. Archer, Ali Rana, David Belada
Journal: Blood
Blood (2024) 144 (Supplement 1): 581.
https://doi.org/10.1182/blood-2024-198023
Published: 2024
Journal Articles

Outcomes By Refractory Status and Prior Therapies Received in Patients with Relapsed/Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL) from the ECHELON-3 Study

Free
Uwe Hahn, Nancy L. Bartlett, Jeong-A Kim, Krimo Bouabdallah, Nicholas Forward, Tsai-Yun Chen, Vincent Camus, Ming-Chung Wang, Philippe Carassou, Enrico Derenzini, Hung Chang, Fritz Offner, Herve Ghesquieres, Grzegorz S. Nowakowski, Christopher Yasenchak, Monica Patterson, Linda Ho, Evelyn Rustia, Michelle Fanale, Keenan Fenton, Craig A. Portell
Journal: Blood
Blood (2024) 144 (Supplement 1): 4489.
https://doi.org/10.1182/blood-2024-200914
Published: 2024
Journal Articles

Exploring the Cell-Free Transcriptome As Biomarker Source in IgM Gammopathies: New Insights from the Fondazione Italiana Linfomi “BIO-WM” Trial

Free
Philippe Decruyenaere, Daniela Drandi, Kimberly Verniers, Simone Ragaini, Jasper Anckaert, Veronica Peri, Elisa Genuardi, Federica Cavallo, Luigi Marcheselli, Irene Dogliotti, Emanuele Cencini, Dario Marino, Angela Ferrari, Simona Tomassetti, Luca Laurenti, Giacomo Loseto, Monia Marchetti, Annelien Morlion, Ramon García-Sanz, Fritz Offner, Benedetto Bruno, Marzia Varettoni, Jo Vandesompele, Simone Ferrero
Journal: Blood
Blood (2024) 144 (Supplement 1): 3297.
https://doi.org/10.1182/blood-2024-198382
Published: 2024
Journal Articles

Durable response after tisagenlecleucel in adults with relapsed/refractory follicular lymphoma: ELARA trial update

Free
Clinical Trials & Observations
Martin Dreyling, Nathan Hale Fowler, Michael Dickinson, Joaquin Martinez-Lopez, Arne Kolstad, Jason Butler, Monalisa Ghosh, Leslie Popplewell, Julio C. Chavez, Emmanuel Bachy, Koji Kato, Hideo Harigae, Marie José Kersten, Charalambos Andreadis, Peter A. Riedell, P. Joy Ho, José Antonio Pérez-Simón, Andy I. Chen, Loretta J. Nastoupil, Bastian von Tresckow, Andrés José María Ferreri, Takanori Teshima, Piers E. M. Patten, Joseph P. McGuirk, Andreas L. Petzer, Fritz Offner, Andreas Viardot, Pier Luigi Zinzani, Ram Malladi, Ines Paule, Aiesha Zia, Rakesh Awasthi, Xia Han, Davide Germano, Darragh O’Donovan, Roberto Ramos, Harald J. Maier, Aisha Masood, Catherine Thieblemont, Stephen J. Schuster
Journal: Blood
Blood (2024) 143 (17): 1713–1725.
https://doi.org/10.1182/blood.2023021567
Published: 2024
Includes: Supplemental data
Journal Articles

Englumafusp Alfa (CD19-4-1BBL) and Glofitamab Combination in Patients with Relapsed/Refractory Non-Hodgkin Lymphoma (R/R NHL): Biomarker Results from a Phase I Dose-Escalation Trial

Free
Koorosh Korfi, Ailsa Christiansen, Zhiwen Jiang, Sabine Wilson, Samuel Tracy, Annika Blank, Sylvia Herter, Natalie Dimier, Bruno Gomes, Pablo Umana, Herve Ghesquieres, Roch Houot, Fritz Offner, Harriet Walter, Nancy L. Bartlett, Guillaume Cartron, Michael Dickinson, William Townsend, Giuseppe Gritti, Francesc Bosch Albareda, Franck Morschhauser, Martin Hutchings, Carmelo Carlo-Stella, Katharina Lechner
Journal: Blood
Blood (2023) 142 (Supplement 1): 3017.
https://doi.org/10.1182/blood-2023-173677
Published: 2023
Journal Articles

Clinical Outcomes of Patients with Relapsed/Refractory Follicular Lymphoma Treated with Tisagenlecleucel: Phase 2 Elara 3-Year Follow-up

Free
Stephen J Schuster, Nathan Fowler, Michael Dickinson, Joaquin Martinez-Lopez, Arne Kolstad, Jason Butler, Monalisa Ghosh, Leslie L. Popplewell, Julio C Chavez, Emmanuel Bachy, Koji Kato, Hideo Harigae, Marie José Kersten, Charalambos Andreadis, Peter A Riedell, Phoebe Joy Ho, Jose A. Perez-Simon, Andy Chen, Loretta J. Nastoupil, Bastian von Tresckow, Andrés José María Ferreri, Takanori Teshima, Piers Patten, Joseph P McGuirk, Andreas L Petzer, Fritz Offner, Andreas Viardot, Pier Luigi Zinzani, Ram Malladi, Aiesha Zia, Rakesh Awasthi, Ines Paule, Davide Germano, Roberto Javier Ramos, Pei Hsu, Catherine Thieblemont, Martin Dreyling
Journal: Blood
Blood (2023) 142 (Supplement 1): 601.
https://doi.org/10.1182/blood-2023-180936
Published: 2023
Journal Articles

Real-World Effectiveness and Safety of Ibrutinib in Patients with Chronic Lymphocytic Leukemia (CLL) in Belgium after 4 Years

Free
Kirsten Saevels, Sylvia Snauwaert, Gaeten Vanstralen, Marc Andre, Fritz Offner, Ariane Maes, Marjolein Lahaye, Ann Janssens
Journal: Blood
Blood (2023) 142 (Supplement 1): 6550.
https://doi.org/10.1182/blood-2023-174762
Published: 2023
Journal Articles

CD19 4-1BBL (RO7227166) a Novel Costimulatory Bispecific Antibody Can be Safely Combined with the T-Cell-Engaging Bispecific Antibody Glofitamab in Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

Free
Martin Hutchings, Carmelo Carlo-Stella, Giuseppe Gritti, Francesc Bosch, Franck Morschhauser, William Townsend, Fritz Offner, Harriet S Walter, Herve Ghesquieres, Roch Houot, Guillaume Cartron, Natalie Dimier, Stephen Fowler, Emma Harrop, Sylvia Herter, Abiraj Keelara, Koorosh Korfi, Jeff Luong, Claudia Mueller, Robert Nutbrown, Giuseppe Palldino, Matt Whayman, Isabel Prieto, Sarah Louise Mycroft, Daria Rukina, Katharina E Lechner, Michael Dickinson
Journal: Blood
Blood (2022) 140 (Supplement 1): 9461–9463.
https://doi.org/10.1182/blood-2022-157011
Published: 2022