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Lorenzo Falchi
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Journal Articles

Zanubrutinib, obinutuzumab, and venetoclax for first-line treatment of mantle cell lymphoma with a  TP53 mutation

Available to Purchase
Clinical Trials & Observations
Anita Kumar, Jacob Soumerai, Jeremy S. Abramson, Jeffrey A. Barnes, Philip Caron, Shalini Chhabra, Maria Chabowska, Ahmet Dogan, Lorenzo Falchi, Clare Grieve, J. Erika Haydu, Patrick Connor Johnson, Ashlee Joseph, Hailey E. Kelly, Alyssa Labarre, Jennifer Kimberly Lue, Rosalba Martignetti, Joanna Mi, Alison Moskowitz, Colette Owens, Sean Plummer, Madeline Puccio, Gilles Salles, Venkatraman Seshan, Elizabeth Simkins, Natalie Slupe, Honglei Zhang, Andrew D. Zelenetz
Journal: Blood
Blood (2025) 145 (5): 497–507.
https://doi.org/10.1182/blood.2024025563
Published: 2025
Includes: Supplemental data
Journal Articles

Pembrolizumab Maintenance Instead of Autologous Hematopoietic Cell Transplantation for Patients with Relapsed or Refractory Hodgkin Lymphoma in Complete Response after Pembrolizumab, Gemcitabine, Vinorelbine, and Liposomal Doxorubicin

Free
Alison Moskowitz, Gunjan L. Shah, Nivetha Ganesan, Tiffany Chang, Esther Drill, Theresa Davey, Helen Hancock, Brittney Munayirji, Monifa Douglas, Alayna M. Santarosa, Ellie Casper, Natasha Galasso, Sarima Subzwari, Marwah Jihad, Alexander P. Boardman, Philip Caron, Kevin A. David, Zachary D. Epstein-Peterson, Lorenzo Falchi, Paola Ghione, Paul A. Hamlin, Steven Horwitz, Andrew M. Intlekofer, William T. Johnson, Anita Kumar, Jennifer Kimberly Lue, Efrat Luttwak, Ariela Noy, Colette Owens, Maria Lia Palomba, Gilles Salles, Raphael Steiner, Robert Stuver, Pallawi Torka, Santosha A. Vardhana, Andrew D. Zelenetz, Joachim Yahalom, Ahmet Dogan, Heiko Schoder, Craig H. Moskowitz
Journal: Blood
Blood (2024) 144 (Supplement 1): 569.
https://doi.org/10.1182/blood-2024-202537
Published: 2024
Journal Articles

Molecular Features Are Associated with Disease Stage in Diffuse Large B-Cell Lymphoma and Reveal Heterogeneity in Patient Outcomes

Free
Manik Uppal, Ashwath Gurumurthi, Paul A. Hamlin, Lorenzo Falchi, Steven Horwitz, Anita Kumar, Ariela Noy, Jennifer Kimberly Lue, Pallawi Torka, Maria E. Arcila, Ahmet Dogan, Brandon S. Imber, Joachim Yahalom, Olivier Elemento, Andrew D. Zelenetz, Gilles Salles, Erel Joffe
Journal: Blood
Blood (2024) 144 (Supplement 1): 4346.
https://doi.org/10.1182/blood-2024-198931
Published: 2024
Journal Articles

A Prospective Geriatric Assessment (GA) Study Predicting Toxicities in Older Adults (OA) with Non-Hodgkin Lymphoma (NHL): Timed up and Go Test (TUG) Time Emerges As a Functional Vital Sign

Free
Pallawi Torka, Esther Drill, Nivetha Ganesan, Regina Truong, Annie Qiu, Walter Ramos Amador, Mayan Oliveros, Alexander P. Boardman, Philip Caron, Kevin A. David, Zachary D. Epstein-Peterson, Lorenzo Falchi, Paola Ghione, Steven Horwitz, Andrew M. Intlekofer, William T. Johnson, Anita Kumar, Jennifer Kimberly Lue, Efrat Luttwak, Alison Moskowitz, Ariela Noy, Colette Owens, Maria Lia Palomba, Raphael E. Steiner, Robert Stuver, Santosha A. Vardhana, Andrew D. Zelenetz, Gilles Salles, Paul A. Hamlin
Journal: Blood
Blood (2024) 144 (Supplement 1): 4474.
https://doi.org/10.1182/blood-2024-210711
Published: 2024
Journal Articles

Final Response and Survival Results from a Phase II Trial of Pembrolizumab and Entinostat in Relapsed/Refractory Hodgkin Lymphoma

Free
Robert Stuver, Santosha A. Vardhana, Nivetha Ganesan, Alexander P. Boardman, Philip Caron, Tiffany Chang, Kevin A. David, Zachary D. Epstein-Peterson, Lorenzo Falchi, Paola Ghione, Paul A. Hamlin, Francisco Hernandez-Ilizaliturri, Steven Horwitz, Andrew M. Intlekofer, William T. Johnson, Reem Karmali, Jennifer Kimberly Lue, Anita Kumar, Efrat Luttwak, Neena Mahajan, Amira Marouf, Ariela Noy, Colette Owens, Maria Lia Palomba, Gilles Salles, Heiko Schoder, David Sermer, Venkatraman Seshan, Raphael E. Steiner, Pallawi Torka, Andrew D. Zelenetz, Gottfried von Keudell, Alison Moskowitz
Journal: Blood
Blood (2024) 144 (Supplement 1): 3053.
https://doi.org/10.1182/blood-2024-210053
Published: 2024
Journal Articles

Real-World Outcomes of Frontline Polatuzumab and Impact of Frailty in Older Adults with Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL)

Free
Varun Iyengar, Jessica Chicola, Ashlee Joseph, Michelle Okwali, Regina Truong, Neil Bapodra, Alexander P. Boardman, Philip Caron, Kevin A. David, Zachary D. Epstein-Peterson, Lorenzo Falchi, Paola Ghione, Anita Kumar, Jennifer Kimberly Lue, Efrat Luttwak, Steven Horwitz, Andrew M. Intlekofer, William T. Johnson, Alison Moskowitz, Ariela Noy, Colette Owens, Maria Lia Palomba, Raphael E. Steiner, Robert Stuver, Santosha A. Vardhana, Andrew D. Zelenetz, Gilles Salles, Paul A. Hamlin, Pallawi Torka
Journal: Blood
Blood (2024) 144 (Supplement 1): 2336.
https://doi.org/10.1182/blood-2024-202741
Published: 2024
Journal Articles

BP43131, a Phase 1 Dose Escalation Study: CD19 Targeted CD28 Costimulatory Agonist (RO7443904) Combined with Glofitamab Shows Promising Efficacy in Patients with Relapsed/Refractory Aggressive B-NHL

Free
Michael J. Dickinson, Martin Hutchings, Franck Morschhauser, Carmelo Carlo-Stella, Lorenzo Falchi, Paolo F. Caimi, Natalie Dimier, Lance Smith, Matt Whayman, Johannes Sam, Abiraj Keelara, Koorosh Korfi, Candice Jamois, Jeremy Gallien, Nicole Martin, Iris Martinez Quetglas, Heather Hinton, Isabel Prieto, Francesca Michielin, Katharina Lechner, Giuseppe Gritti
Journal: Blood
Blood (2024) 144 (Supplement 1): 3123.
https://doi.org/10.1182/blood-2024-205544
Published: 2024
Journal Articles

Dual-Targeted Therapy with Ruxolitinib Plus Duvelisib for T-Cell Lymphoma

Free
Alison Moskowitz, Nivetha Ganesan, Tiffany Chang, Theresa Davey, Helen Hancock, Marcel Smith, Alicia Assini, Lisa Sarmasti, Tayler Miller, Angela Gibaldi, Jonathan H. Schatz, Eric D. Jacobsen, Shamir Geller, Patricia Myskowski, Anita Kumar, Jennifer Kimberly Lue, Lorenzo Falchi, Robert Stuver, Paola Ghione, Zachary D. Epstein-Peterson, William T. Johnson, Kimon V Argyropoulos, Katherine Lopez, Kelly Hannigan, Win Su Thet, Katie Ksanznak, Suviasini Patel, Maria Salas, Sarima Subzwari, Marwah Jihad, Ellie Casper, Natasha Galasso, Heiko Schoder, Ahmet Dogan, Santosha A. Vardhana, Steven Horwitz
Journal: Blood
Blood (2024) 144 (Supplement 1): 463.
https://doi.org/10.1182/blood-2024-206462
Published: 2024
Journal Articles

Fixed-Duration Epcoritamab + R-CHOP Induces High Complete Response Rates in Patients with Previously Untreated Diffuse Large B-Cell Lymphoma Withhigh-Risk Features: Long-Term Results from the Epcore NHL-2 Trial

Free
Lorenzo Falchi, Fritz Offner, Sven de Vos, Joshua Brody, Raul Cordoba, Kim Linton, Sylvia Snauwaert, Michael Roost Clausen, Toshihiko Oki, Andrew J. Steele, Yi Hao, Kimberly G. Archer, Ali Rana, David Belada
Journal: Blood
Blood (2024) 144 (Supplement 1): 581.
https://doi.org/10.1182/blood-2024-198023
Published: 2024
Journal Articles

Fixed-Duration Epcoritamab + R 2 Drives Deep and Durable Responses in Patients with Relapsed or Refractory Follicular Lymphoma: 2-Year Follow-up from Arm 2 of the Epcore NHL-2 Trial

Free
Lorenzo Falchi, Anna Sureda Balari, Sirpa Leppä, Joost S.P. Vermaat, Marcel Nijland, Jacob Haaber Christensen, Sven de Vos, Harald Holte, Reid W. Merryman, Pieternella Lugtenburg, Pau Abrisqueta Costa, Kim Linton, Gauri Sunkersett, Christopher Morehouse, Andrew J. Steele, Jennifer Marek, Liwei Wang, Daniela Hoehn, Martin Hutchings, David Belada
Journal: Blood
Blood (2024) 144 (Supplement 1): 342.
https://doi.org/10.1182/blood-2024-200262
Published: 2024
Journal Articles

Single-Agent Mosunetuzumab Produces High Complete Response Rates in Patients with Newly Diagnosed Follicular Lymphoma: Primary Analysis of the Mithic-FL1 Trial

Free
Lorenzo Falchi, Michelle Okwali, Alexandra Ferreira Lopes, Paul A. Hamlin, Jennifer Kimberly Lue, Paola Ghione, Colette Owens, Pallawi Torka, Anita Kumar, Raphael Steiner, Zachary D. Epstein-Peterson, Maria Lia Palomba, Robert Stuver, Ariela Noy, Anastasia Martinova, Lauren Wood, Clare Grieve, Walter Ramos Amador, Santosha A. Vardhana, Andrew D. Zelenetz, Lori A. Leslie, Joseph L. Roswarski, Kieron Dunleavy, Andre Goy, Gilles Salles
Journal: Blood
Blood (2024) 144 (Supplement 1): 340.
https://doi.org/10.1182/blood-2024-205046
Published: 2024
Journal Articles

Multicenter Phase II Trial of Zanubrutinib, Obinutuzumab, and Venetoclax (BOVen) in Treatment-Naïve Chronic Lymphocytic Leukemia: 5-Year Follow up, Retreatment Outcomes, and Impact of MRD Kinetics (ΔMRD400)

Free
Jacob D. Soumerai, Ahmet Dogan, Venkatraman Seshan, Kelsey Leigh Flaherty, Natalie Slupe, Jason Carter, Ephraim Hochberg, Jeffrey A. Barnes, Jeremy S. Abramson, Audrey Hamilton, Ariela Noy, Colette Owens, Maria Lia Palomba, Anita Kumar, Lindsey Roeker, Meghan C. Thompson, Ronald W. Takvorian, Zachary D. Epstein-Peterson, Mark Blaine Geyer, Gilles Salles, Robert Stuver, Philip Caron, Prioty Islam, Tamanna Haque, Paola Ghione, Raphael E. Steiner, Pallawi Torka, Kevin A. David, Jennifer Kimberly Lue, Paul A. Hamlin, Alison Moskowitz, Lorenzo Falchi, Julie Haydu, Patrick Connor Johnson, Joanna Mi, Jessica Pendleton, Alyssa Labarre, Rosalba Martignetti, Sean F. Plummer, Maria Chabowska, Walter Ramos Amador, Neena Mahajan, Morgan Choma, Clare Grieve, Rayna N. Garcia, Hailey E. Kelly, Ella Mallinger, James O'Grady, Bernadette Beatty, Michelle Adams, Athina Apazidis, Aileen Cleary Cohen, Mina Shahkarami, Allison P. Jacob, Omar Abdel-Wahab, Andrew D. Zelenetz
Journal: Blood
Blood (2024) 144 (Supplement 1): 1867.
https://doi.org/10.1182/blood-2024-205697
Published: 2024
Journal Articles

Sequential R-CHOP/(R)-ICE and Dose-Adjusted EPOCH-R Are Both Appropriate Frontline Treatments for Newly Diagnosed Primary Mediastinal B-Cell Lymphoma: Results of a Retrospective Analysis

Free
Kurt S. Bantilan, Efrat Luttwak, Craig H. Moskowitz, Matthew Matasar, David J. Straus, Carol S. Portlock, Alison Moskowitz, Ariela Noy, Maria Lia Palomba, Steven Horwitz, Gilles Salles, Colette Owens, Pallawi Torka, Alexander P. Boardman, Kevin A. David, Zachary D. Epstein-Peterson, Anita Kumar, Philip Caron, Paola Ghione, Lorenzo Falchi, Jennifer K Lue, Raphael Steiner, Robert Stuver, Ahmet Dogan, Paul A. Hamlin, Andrew D. Zelenetz
Journal: Blood
Blood (2024) 144 (Supplement 1): 4485.
https://doi.org/10.1182/blood-2024-205803
Published: 2024
Journal Articles

When Can We Define Cure after CAR-T Therapy in LBCL? Insights from Serial Landmark Analyses

Free
Marina Gomez-Llobell, Roni Shouval, Samantha Brown, Noa Golan Accav, Sean M. Devlin, Magdalena Corona, Kai Rejeski, Alfredo Rivas-Delgado, Alejandro Luna, Efrat Luttwak, Sandeep S. Raj, Mohammad Alhomoud, Ronit Marcus, Avichai Shimoni, Shimrit Ringelstein-Harlev, Alexander P. Boardman, Parastoo B Dahi, Richard J. Lin, Michael Scordo, Lorenzo Falchi, Gunjan L. Shah, Maria Lia Palomba, Gilles Salles, Jae H. Park, Ofrat Beyar-Katz, Abraham Avigdor, Miguel Angel Perales
Journal: Blood
Blood (2024) 144 (Supplement 1): 2369.
https://doi.org/10.1182/blood-2024-201029
Published: 2024
Journal Articles

Comparative Real-World Outcomes of Commercial CD19-Directed CAR T-Cell Therapies in Large B-Cell Lymphoma

Free
Xavier Deschênes-Simard, Maria Bromberg, Sean M. Devlin, Ofrat Beyar Katz, Andrew Ip, Ronit Marcus, Abraham Avigdor, Annamaria Ballweg, Emma Rabinovich, Mohammad Alhomoud, Alfredo Rivas-Delgado, Magdalena Corona, Alejandro Luna De Abia, Maria Lia Palomba, Gunjan L. Shah, Richard J. Lin, Alexander P. Boardman, Lorenzo Falchi, Jennifer Kimberly Lue, Gilles Salles, Miguel-Angel Perales, Roni Shouval, Parastoo B Dahi, Michael Scordo
Journal: Blood
Blood (2024) 144 (Supplement 1): 3752.
https://doi.org/10.1182/blood-2024-211475
Published: 2024
Journal Articles

Fixed-Duration Epcoritamab in Combination with Bendamustine + Rituximab for First-Line Treatment of Follicular Lymphoma: Initial Results from Epcore NHL-2 Arm 3

Free
Joshua Brody, Lorenzo Falchi, Umberto Vitolo, Marcel Nijland, Fritz Offner, Sylvia Snauwaert, Poliana Patah, Jennifer Marek, Christopher Morehouse, Andrew J. Steele, Yi Hao, Daniela Hoehn, Kim Linton
Journal: Blood
Blood (2024) 144 (Supplement 1): 1627.
https://doi.org/10.1182/blood-2024-200369
Published: 2024
Journal Articles

Impact of Broad-Spectrum Antibiotic Exposure on CAR-T Therapy Outcomes in B-Cell Lymphoma: A Multicenter International Study

Free
Roni Shouval, Teng Fei, Giulia Gabrielli, Natalie Grier Smith, Guido Ghilardi, John Slingerland, Jonathan U. Peled, Ying Taur, Sunita D. Nasta, Alejandro Luna, Magdalena Corona, Kai Rejeski, Sophia Stock, Ronit Marcus, Noa Golan Accav, Ofrat Beyar-Katz, Hazim Khatib, Sandeep S. Raj, Alexander P. Boardman, Parastoo B Dahi, Richard J. Lin, Michael Scordo, Lorenzo Falchi, Jakub Svoboda, Elise A. Chong, Stefan K. Barta, Daniel J. Landsburg, Avichai Shimoni, Arnon Nagler, Gunjan L. Shah, Maria Lia Palomba, Gilles Salles, Jae H. Park, Stephen J. Schuster, Tsila Zuckerman, Marion Subklewe, Abraham Avigdor, Miguel Angel Perales, Marcel R.M. van den Brink, Marco Ruella
Journal: Blood
Blood (2024) 144 (Supplement 1): 1746.
https://doi.org/10.1182/blood-2024-203871
Published: 2024
Journal Articles

High Grade B-Cell Lymphoma with MYC/BCL6-Rearrangements (R) May Have Inferior Outcomes Compared to BCL2-R Disease

Free
Sean E. Healton, Efrat Luttwak, Alfredo Rivas-Delgado, Alexander P. Boardman, Philip Caron, Kevin A. David, Zachary D. Epstein-Peterson, Lorenzo Falchi, Paola Ghione, Paul A. Hamlin, Steven Horwitz, Andrew M. Intlekofer, William T. Johnson, Anita Kumar, Alison Moskowitz, Ariela Noy, Maria Lia Palomba, Raphael E. Steiner, Robert Stuver, Pallawi Torka, Santosha A. Vardhana, Andrew D. Zelenetz, Venkatraman Seshan, Pallavi Galera, Ahmet Dogan, Gilles Salles, Jennifer Lue
Journal: Blood
Blood (2024) 144 (Supplement 1): 1707.
https://doi.org/10.1182/blood-2024-194144
Published: 2024
Journal Articles

CD19-CD28 (RO7443904) Combination with Glofitamab Enhances T-Cell Proliferation and Effector Function in Patients with Relapsed/Refractory Non-Hodgkin Lymphoma (R/R NHL)

Free
Koorosh Korfi, Sabine Wilson, Zhiwen Jiang, Ailsa Christiansen, Sreenath Krishnan, Candice Jamois, Annika Blank, Alexandra Epp, Abraham Silva, Philip Knuckles, Joanne Hayward, Johannes Sam, Katharina Lechner, Natalie Dimier, Paolo F. Caimi, Lorenzo Falchi, Giuseppe Gritti, Franck Morschhauser, Martin Hutchings, Michael J. Dickinson, Carmelo Carlo-Stella
Journal: Blood
Blood (2024) 144 (Supplement 1): 644.
https://doi.org/10.1182/blood-2024-201406
Published: 2024
Journal Articles

Fixed-Duration Glofitamab Monotherapy Continues to Demonstrate Durable Responses in Patients with Relapsed or Refractory Large B-Cell Lymphoma: 3-Year Follow-up from a Pivotal Phase II Study

Free
Michael J. Dickinson, Carmelo Carlo-Stella, Franck Morschhauser, Emmanuel Bachy, Guillaume Cartron, Paolo Corradini, Nancy L. Bartlett, Gloria Iacoboni, Cyrus Khan, Mark S. Hertzberg, Lorenzo Falchi, Joshua Brody, Marek Trněný, Estefania Mulvihill, Aurelien Berthier, Alessia Bottos, James Relf, Fabiola Bene Tchaleu, Linda Lundberg, Martin Hutchings
Journal: Blood
Blood (2024) 144 (Supplement 1): 865.
https://doi.org/10.1182/blood-2024-194333
Published: 2024