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Jonathan H. Schatz
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Journal Articles

Clonal Evolution of Lymphoid Malignancies Following the Mutagenic Impact of Radiotherapy

Free
Benjamin Diamond, Dhanvantri Chahar, Michael D. Jain, Alexandra Maria Poos, Michael Durante, Bachisio Ziccheddu, Marcella Kaddoura, Marios Papadimitriou, Kylee H Maclachlan, Tomas Jelinek, Faith E Davies, Nicholas B Figura, Gareth Morgan, Elias K. Mai, Hartmut Goldschmidt, Katja C. Weisel, Roland Fenk, Saad Z. Usmani, Ola Landgren, Frederick Locke, Marc S. Raab, Jonathan H. Schatz, Niels Weinhold, Francesco Maura
Journal: Blood
Blood (2024) 144 (Supplement 1): 1607.
https://doi.org/10.1182/blood-2024-200927
Published: 2024
Journal Articles

Dual-Targeted Therapy with Ruxolitinib Plus Duvelisib for T-Cell Lymphoma

Free
Alison Moskowitz, Nivetha Ganesan, Tiffany Chang, Theresa Davey, Helen Hancock, Marcel Smith, Alicia Assini, Lisa Sarmasti, Tayler Miller, Angela Gibaldi, Jonathan H. Schatz, Eric D. Jacobsen, Shamir Geller, Patricia Myskowski, Anita Kumar, Jennifer Kimberly Lue, Lorenzo Falchi, Robert Stuver, Paola Ghione, Zachary D. Epstein-Peterson, William T. Johnson, Kimon V Argyropoulos, Katherine Lopez, Kelly Hannigan, Win Su Thet, Katie Ksanznak, Suviasini Patel, Maria Salas, Sarima Subzwari, Marwah Jihad, Ellie Casper, Natasha Galasso, Heiko Schoder, Ahmet Dogan, Santosha A. Vardhana, Steven Horwitz
Journal: Blood
Blood (2024) 144 (Supplement 1): 463.
https://doi.org/10.1182/blood-2024-206462
Published: 2024
Journal Articles

Intrinsic Tumor Drivers and Immune Escape Mechanisms in CD19 CAR T-Cell Therapy Resistance for Aggressive Large B Cell Lymphoma

Free
Bachisio Ziccheddu, Michael D. Jain, Monika Chojnacka, Michael Durante, Venu Venkatarame Gowda Saralamma, Austin Daniel Newsam, Jerald Noble, Nicholas B Figura, Meghan Menges, Ola Landgren, Marco Davila, Jonathan H. Schatz, Francesco Maura, Frederick L. Locke
Journal: Blood
Blood (2024) 144 (Supplement 1): 232.
https://doi.org/10.1182/blood-2024-208372
Published: 2024
Journal Articles

Translational Disruption of NRF2 By Zotatifin Enhances Sensitivity to Ferroptosis and CAR-T Cells in Diffuse Large B-Cell Lymphoma

Free
Paola Manara, Venu Venkatarame Gowda Saralamma, Austin Daniel Newsam, Marco Vincenzo Russo, Tyler Andrew Cunningham, Alicia Bilbao Martinez, Nikolai Fattakhov, Kyle Hoffman, Alexandra Marie Carbone, Abdessamad Youssfi Alaoui, Dhanvantri Chahar, Olivia Barbara Lightfuss, Francesco Maura, Daniel Bilbao, Jonathan H. Schatz
Journal: Blood
Blood (2024) 144 (Supplement 1): 4167.
https://doi.org/10.1182/blood-2024-203442
Published: 2024
Journal Articles

Clinical Features, Therapy Patterns and Survival Outcomes of Limited-Stage Peripheral T-Cell Lymphomas: A Cross-Continental Study

Free
Juan Esteban Garcia-Robledo, Henry Quintero, Denisse Castro, Brady E Beltran, Daniel J Enriquez, Jule F Vasquez, Claudia Roche, Daniel Artiles, Fabiola Valvert, Luis Mario Villela Martinez, Juliana Pereira, Ana Carolina Oliver, Jamila Vaz Tavarez, Sergio Augusto B Brasil, Karin Z Cecyn, Nelson S Castro, Renata Lyrio R Baptista, Samuel S. Medina, Davimar Miranda Maciel Borducchi, Marcelo Bellesso, Danielle Leão Cordeiro De Farias, Yung Gonzaga, Laura Korin, Patricio Pereyra, Camila Peña, Macarena Roa, Maria Alejandra Torres Viera, Kelly Meza, Seisha Von Glasenapp, Alfredo Quiroz, Cesar Samanez-Figari, Rosa Oliday Rios Jimenez, Sally Paredes, Thais Fischer, Asaad Trabolsi, Jonathan H. Schatz, Swaminathan P Iyer, Ranjit Nair, Eduardo Edelman Saul, Casey Bermack, Jorge J. Castillo, Carmino De Souza, Eliana Miranda, Bryan Valcarcel, Carlos Chiattone, Luis Enrique Malpica Castillo
Journal: Blood
Blood (2024) 144 (Supplement 1): 1687.
https://doi.org/10.1182/blood-2024-205881
Published: 2024
Journal Articles

The Cyclin-G Associated Kinase (GAK) Is a Critical Targetable Dependency for Successful Mitosis By Diffuse Large B-Cell Lymphomas Linked to Retinoblastoma Loss of Function

Free
Olivia Barbara Lightfuss, Preet Kumar, Austin Daniel Newsam, Lingxiao Li, Pierre A. Younes, Toral Shastri, Abdessamad Youssfi Alaoui, Diego E. Hernandez Parets, Paola Manara, Daniel Bilbao, Stephan Schürer, Vance P. Lemmon, Francesco Maura, Yangbo Feng, Hassan A. Ali, Jonathan H. Schatz
Journal: Blood
Blood (2024) 144 (Supplement 1): 2781.
https://doi.org/10.1182/blood-2024-206073
Published: 2024
Journal Articles

Refining Prognostication in Peripheral T Cell Lymphoma (PTCL): A Risk-Adapted Prognostic Model for Patients with Limited-Stage PTCL

Free
Carolina Romero, Macarena Roa, Henry Idrobo, Denisse Castro, Brady E Beltran, Daniel J Enriquez, Jule F Vasquez, Claudia Roche, Daniel Artiles, Fabiola Valvert, Luis Mario Villela Martinez, Juliana Pereira, Ana Carolina Oliver, Jamila Vaz Tavarez, Sergio Augusto B Brasil, Karin Z Cecyn, Nelson S Castro, Renata Lyrio R Baptista, Samuel S. Medina, Davimar Miranda Maciel Borducchi, Marcelo Bellesso, Danielle Leão Cordeiro De Farias, Yung Gonzaga, Laura Korin, Patricio Pereyra, Camila Peña, Maria Alejandra Torres Viera, Kelly Meza, Seisha Von Glasenapp, Alfredo Quiroz, Cesar Samanez-Figari, Rosa Oliday Rios Jimenez, Sally Paredes, Thais Fischer, Asaad Trabolsi, Jonathan H. Schatz, Swaminathan P Iyer, Ranjit Nair, Eduardo Edelman Saul, Casey Bermack, Jorge J. Castillo, Carmino De Souza, Eliana Miranda, Bryan Valcarcel, Carlos Chiattone, Luis Enrique Malpica Castillo
Journal: Blood
Blood (2024) 144 (Supplement 1): 983.
https://doi.org/10.1182/blood-2024-205295
Published: 2024
Journal Articles

Decoding the Pivotal Roles of BCL10 Activating Mutations in DLBCL Drug Resistance and Lymphomagenesis

Free
Caroline A. Coughlin, Dhanvantri Chahar, Marianna Lekakis, Hsuan-Ting Huang, Abdessamad Youssfi Alaoui, Lingxiao Li, Evan Roberts, Natalia Campos Gallego, Claude-Henry Volmar, Ola Landgren, Shaun Brothers, Anthony Griswold, Catalina Amador, Daniel Bilbao, Francesco Maura, Jonathan H. Schatz
Journal: Blood
Blood (2024) 144 (Supplement 1): 829.
https://doi.org/10.1182/blood-2024-203545
Published: 2024
Journal Articles

Loncastuximab Tesirine with Rituximab Induces Robust and Durable Complete Metabolic Responses in High-Risk Relapsed/Refractory Follicular Lymphoma

Free
Juan Pablo Alderuccio, Alvaro J Alencar, Jonathan H. Schatz, Russ Kuker, David Sicre, Georgios Pongas, Isildinha M. Reis, Jay Y. Spiegel, Laura Medina Andara, Lazaros J. Lekakis, Joseph S. Gyedu, Jose Sandoval-Sus, Amer M. Beitinjaneh, Michele D. Stanchina, Asaad Trabolsi, Izidore S. Lossos, Joseph D. Rosenblatt, David S. Lessen, Craig H. Moskowitz
Journal: Blood
Blood (2024) 144 (Supplement 1): 337.
https://doi.org/10.1182/blood-2024-199093
Published: 2024
Journal Articles

TP53 -Altered Aggressive Large B-Cell Lymphoma (LBCL) Outcomes By Treatment Modality: A Multicenter Cohort from 14 U.S. Centers

Free
Cassandra Duarte, Grace Bosma, Diana Abbott, Gaston Jean-Louis, Maciej Kabat, Daniel Stapor, Nancy Musoke, Brian T. Hill, Alexander Gorzewski, Tharakeswari Selvakumar, Asaad Trabolsi, Megan Greenberg, Alec Hansen, Neil Bailey, Mazyar Shadman, Ellen K Kendall, Nausheen Ahmed, Forat Lutfi, Patrick Connor Johnson, Mengyang Di, Krish Patel, Allison M. Bock, Joanna Rhodes, Jonathan H. Schatz, Brian Hess, Reem Karmali, Zachary AK Frosch, Andrew Ip, Hua-Jay J Cherng, Jagar Jasem, Steven M. Bair, Bradley M. Haverkos, Manali Kamdar, Ajay Major
Journal: Blood
Blood (2024) 144 (Supplement 1): 6451.
https://doi.org/10.1182/blood-2024-194844
Published: 2024
Journal Articles

Enhanced Ferroptosis Induction Susceptibility in Diffuse Large B-Cell Lymphoma through Rocaglate-Mediated Translation Inhibition

Free
Paola Manara, Alexa Barroso, Abdessamad Youssfi Alaoui, Tyler A Cunningham, David H. Ho, Kyle Hoffman, Jonathan H. Schatz
Journal: Blood
Blood (2023) 142 (Supplement 1): 2814.
https://doi.org/10.1182/blood-2023-187443
Published: 2023
Journal Articles

Limited Duration Loncastuximab Tesirine with Rituximab Induces High Complete Metabolic Response Rate in High-Risk Relapsed/Refractory Follicular Lymphoma - a Phase 2 Study

Free
Juan Pablo Alderuccio, Alvaro J. Alencar, Jonathan H. Schatz, Russ Kuker, Georgio Pongas, Isildinha M. Reis, Jay Y. Spiegel, Laura Medina Andara, Lazaros J. Lekakis, Joseph S. Gyedu, Jose Sandoval-Sus, Amer M. Beitinjaneh, Nathalie Padron, Izidore S. Lossos, Joseph D. Rosenblatt, David S. Lessen, Craig H. Moskowitz
Journal: Blood
Blood (2023) 142 (Supplement 1): 984.
https://doi.org/10.1182/blood-2023-178825
Published: 2023
Journal Articles

Clinical Impact of Neoantigen Burden and HLA Loss in Aggressive B-Cell Lymphomas Treated with CD19 CAR T-Cell

Free
Bachisio Ziccheddu, Michael D. Jain, Monika Chojnacka, Michael Durante, Julieta Abraham Miranda, Meghan Menges, Ola Landgren, Marco Davila, Jonathan H. Schatz, Francesco Maura, Frederick L. Locke
Journal: Blood
Blood (2023) 142 (Supplement 1): 4362.
https://doi.org/10.1182/blood-2023-182821
Published: 2023
Journal Articles

The Marine Product Elatol Is a Novel Inhibitor of Mitochondrial Translation Triggering the Integrated Stress Response and Apoptosis in Leukemia and Lymphoma Cells

Free
Tyler A. Cunningham, Priyanka Maiti, Paola Manara, Vivek Singh, Nigel Beaton, Alexey Amunts, Flavia Fontanesi, Antonio Barrientos, Jonathan H. Schatz
Journal: Blood
Blood (2022) 140 (Supplement 1): 7819.
https://doi.org/10.1182/blood-2022-166899
Published: 2022
Journal Articles

Translatome Reprogramming By Rocaglates in Lymphoma Induces Drug Resistance through up-Regulation of CD98hc, Activating Downstream AKT Survival Signaling

Free
Paola Manara, Tyler A. Cunningham, J.J. David Ho, Caroline A. Coughlin, Jonathan H. Schatz
Journal: Blood
Blood (2022) 140 (Supplement 1): 8844.
https://doi.org/10.1182/blood-2022-166771
Published: 2022
Journal Articles

Poor Survival Outcomes of Checkpoint Inhibitors for B-Cell Lymphomas Relapsing after or Refractory to CAR T-Cell Therapy: A Real-World Cohort from 15 U.S. Academic Institutions

Free
Ajay Major, Jovian Yu, Navika D. Shukla, Rachel Treitman, Manali K. Kamdar, Bradley M. Haverkos, James Godfrey, Melissa A. Babcook, Timothy J. Voorhees, Sophie G Carlson, Daria Gaut, Caspian Oliai, Jason T. Romancik, Allison Winter, Brian T. Hill, Radhika Bansal, Jose C. Villasboas, Imran A. Nizamuddin, Reem Karmali, Lindsey A. Fitzgerald, Deborah M. Stephens, Priyanka A. Pophali, Asaad Trabolsi, Jonathan H. Schatz, Marie Hu, Veronika Bachanova, Michael J Slade, Nathan Singh, Nausheen Ahmed, Joseph P. McGuirk, Michael R. Bishop, Peter A. Riedell, Justin Kline
Journal: Blood
Blood (2022) 140 (Supplement 1): 1328–1331.
https://doi.org/10.1182/blood-2022-157829
Published: 2022
Journal Articles

The Cyclin-G Associated Kinase (GAK) Is a Critical Dependency for Cell-Cycle Progression in Diffuse Large B-Cell Lymphoma Associated with Deregulation of the Retinoblastoma Tumor Suppressor

Free
Austin D. Newsam, Preet Kumar, Olivia B. Lightfuss, Lingxiao Li, Anirban Ghoshal, Stephan Schürer, Vance Lemmon, Yangbo Feng, Hassan Al-Ali, Jonathan H. Schatz
Journal: Blood
Blood (2022) 140 (Supplement 1): 2261–2262.
https://doi.org/10.1182/blood-2022-164697
Published: 2022
Journal Articles

Whole-genome sequencing reveals complex genomic features underlying anti-CD19 CAR T-cell treatment failures in lymphoma

Free
Michael D. Jain, Bachisio Ziccheddu, Caroline A. Coughlin, Rawan Faramand, Anthony J. Griswold, Kayla M. Reid, Meghan Menges, Yonghong Zhang, Ling Cen, Xuefeng Wang, Mohammad Hussaini, Ola Landgren, Marco L. Davila, Jonathan H. Schatz, Frederick L. Locke, Francesco Maura
Journal: Blood
Blood (2022) 140 (5): 491–503.
https://doi.org/10.1182/blood.2021015008
Published: 2022
Includes: Supplemental data
Journal Articles

A phase 2 biomarker-driven study of ruxolitinib demonstrates effectiveness of JAK/STAT targeting in T-cell lymphomas

Free
Clinical Trials & Observations
Alison J. Moskowitz, Paola Ghione, Eric Jacobsen, Jia Ruan, Jonathan H. Schatz, Sarah Noor, Patricia Myskowski, Santosha Vardhana, Nivetha Ganesan, Helen Hancock, Theresa Davey, Leslie Perez, Sunyoung Ryu, Alayna Santarosa, Jack Dowd, Obadi Obadi, Lauren Pomerantz, Nancy Yi, Samia Sohail, Natasha Galasso, Rachel Neuman, Brielle Liotta, William Blouin, Jeeyeon Baik, Mark B. Geyer, Ariela Noy, David Straus, Priyadarshini Kumar, Ahmet Dogan, Travis Hollmann, Esther Drill, Jurgen Rademaker, Heiko Schoder, Giorgio Inghirami, David M. Weinstock, Steven M. Horwitz
Journal: Blood
Blood (2021) 138 (26): 2828–2837.
https://doi.org/10.1182/blood.2021013379
Published: 2021
Includes: Supplemental data
Journal Articles

Genomic Drivers of Large B-Cell Lymphoma Resistance to CD19 CAR-T Therapy

Free
Michael D. Jain, Bachisio Ziccheddu, Caroline A. Coughlin, Rawan Faramand, Anthony J. Griswold, Kayla M Reid, Ola Landgren, Frederick L. Locke, Francesco Maura, Marco L. Davila, Jonathan H. Schatz
Journal: Blood
Blood (2021) 138 (Supplement 1): 42.
https://doi.org/10.1182/blood-2021-148605
Published: 2021