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Maximilian Merz
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Journal Articles

Functionally high-risk disease is associated with inferior outcomes after chimeric antigen receptor T-cell therapy for relapsed refractory multiple myeloma

Free
Tara Sebastian, Hamza Hashmi, Ross Firestone, Eric Jurgens, Sridevi Rajeeve, Tasmin Farzana, Maximilian Merz, Carlyn Tan, Kylee Maclachlan, Francesco Maura, Neha Korde, Hani Hassoun, Urvi Shah, Malin Hultcrantz, Heather Landau, Michael Scordo, Alexander Lesokhin, Andriy Derkach, David Nemirovsky, Sergio Giralt, Sham Mailankody, Saad Usmani
Journal: Blood
Blood (2025) 146 (Supplement 1): 2291.
https://doi.org/10.1182/blood-2025-2291
Published: 2025
Journal Articles

Sarcopenia and body composition predict survival and reveal immunometabolic dysfunction via single-cell profiling in anti-BCMA CAR T-treated myeloma

Free
Thomas Wiemers, Michael Rade, Nora Grieb, Maximilian Ferle, Tihomir Dermendzhiev, David Fandrei, Patrick Born, Sabine Seiffert, Anja Grahnert, Maik Friedrich, Ronny Baber, Markus Kreuz, Klaus Metzeler, Marco Herling, Carmen Herling, Madlen Jentzsch, Georg-Nikolaus Franke, Andreas Boldt, Ulrike Koehl, Kristin Reiche, Timm Denecke, Urvi Shah, Uwe Platzbecker, Vladan Vucinic, Hans-Jonas Meyer, Maximilian Merz
Journal: Blood
Blood (2025) 146 (Supplement 1): 7676.
https://doi.org/10.1182/blood-2025-7676
Published: 2025
Journal Articles

Impact of renal impairment and lymphodepletion regimen on outcomes after CAR T-cell therapy in relapsed/refractory multiple myeloma

Free
Nora Grieb, Thomas Wiemers, Patrick Born, David Fandrei, Luise Fischer, Maximilian Ferle, Song-Yau Wang, Madlen Jentzsch, Carmen Herling, Klaus Metzeler, Marco Herling, Simone Heyn, Uwe Platzbecker, Vladan Vucinic, Thomas Neumuth, Georg-Nikolaus Franke, Maximilian Merz
Journal: Blood
Blood (2025) 146 (Supplement 1): 5853.
https://doi.org/10.1182/blood-2025-5853
Published: 2025
Journal Articles

Endothelial dysfunction and proinflammatory state determine severe hematotoxicity and adverse outcome of CAR-T therapy

Free
Lukas Scheller, Xiang Zhou, Markus Kreuz, Henry Loeffler-Wirth, Sofie-Katrin Kadel, Sven Schimanski, Hannah Schulze, Anna Marie Ruckdeschel, Florian Eisele, Verena Konetzki, Maria Jornet Culubret, Julia Mersi, Johannes Waldschmidt, Sophia Danhof, Maximilian Merz, Ulrike Koehl, K. Martin Kortüm, Leo Rasche, Hermann Einsele, Johannes Duell, Prof. Dr. Max S Topp, Michael Hudecek, Kristin Reiche, Miriam Alb
Journal: Blood
Blood (2025) 146 (Supplement 1): 809.
https://doi.org/10.1182/blood-2025-809
Published: 2025
Journal Articles

CAR T-cells or bispecific antibodies for relapsed/refractory multiple myeloma: Head-to-head real-world european comparison

Free
Maximilian Merz, Tomas Jelinek, Thomas Pabst, Raphael Teipel, Anca-Maria Albici, Bastian von Tresckow, Marcel Teichert, Uta Demel, Antonia Busse, Marie Wesener, Tobias A.W. Holderried, Friederike Schmitz, Fabian Müller, Friedrich-Linus Roessiger, Barbara Jeker, Michele Hoffmann, Natalie Schub, Natalia Tovar, Ben-Niklas Baermann, Stork Martin, Alexandra Jungova, Jiri Minarik, Jakub Radocha, Ivan Špička, Ludek Pour, Polona Novak, Klara Slajpah, Karla Rener, Matjaz Sever, Ulrich Keller, Stephan Bohl, Francis Ayuk, David Fandrei, Patrick Born, Vladan Vucinic, Nicolaus Kroeger, Irene Strassl, Friedrich Stoelzel, Roman Hajek, Carlos Fernandez de Larrea, Nico Gagelmann
Journal: Blood
Blood (2025) 146 (Supplement 1): 4590.
https://doi.org/10.1182/blood-2025-4590
Published: 2025
Journal Articles

Sequential targeting in multiple myeloma: talquetamab, a GPRC5D bispecific antibody, as a bridge to BCMA CAR-T therapy

Available to Purchase
Clinical Trials & Observations
Binod Dhakal, Othman S. Akhtar, David Fandrei, Alexandria Jensen, Rahul Banerjee, Darren Pan, Shambavi Richard, Reed Friend, Matthew Rees, Patrick Costello, Mariola Vazquez Martinez, Oren Pasvolsky, Charlotte Wagner, James A. Davis, Omar Castaneda Puglianini, Ran Reshef, Aimaz Afrough, Danai Dima, Manisha Bhutani, Omar Nadeem, Ricardo Parrondo, Ciara Freeman, Lekha Mikkilineni, Shahzad Raza, Larry D. Anderson Jr, Prashant Kapoor, Hitomi Hosoya, Saurabh Chhabra, Ariel Grajales-Cruz, Mahmoud Gaballa, Shonali Midha, Melissa Alsina, Douglas Sborov, Krina Patel, Yi Lin, Christopher Ferreri, Nico Gagelmann, Anupama Kumar, Doris Hansen, Andrew Cowan, Luciano J. Costa, Maximilian Merz, Surbhi Sidana
Journal: Blood
Blood (2025) 146 (17): 2063–2072.
https://doi.org/10.1182/blood.2025029773
Published: 2025
Includes: Supplemental data
Journal Articles

Remission conversion drives outcomes after CAR T-cell therapy for multiple myeloma: a registry analysis from the DRST

Available to Purchase
Clinical Trials & Observations
Maximilian Merz, Nico Gagelmann, Samih Smaili, Sarah Flossdorf, Sandra Sauer, Christof Scheid, Bastian von Tresckow, Gerald Wulf, Katja Weisel, Igor Wolfgang Blau, Monika Engelhardt, Ralph Wäsch, Natalie Schub, Raphael Teipel, Judith Hecker, Johannes Waldschmidt, Britta Besemer, Ben-Niklas Baermann, Simon Call, Leo Hansmann, Francis Ayuketang Ayuk, Marc S. Raab, Hermann Einsele, Uwe Platzbecker, Nicolaus Kröger
Journal: Blood
Blood (2025) 146 (14): 1677–1686.
https://doi.org/10.1182/blood.2025028330
Published: 2025
Includes: Supplemental data
Journal Articles

Losing CD38 in myeloma

Free
Maximilian Merz
Journal: Blood
Blood (2025) 146 (13): 1529–1530.
https://doi.org/10.1182/blood.2025029889
Published: 2025
Journal Articles

Salvage autologous transplant in relapsed multiple myeloma: long-term follow-up of the phase 3 GMMG ReLApsE trial

Open Access
Clinical Trials & Observations Brief Report
Marc-Andrea Baertsch, Jana Schlenzka, Thomas Hielscher, Marc S. Raab, Sandra Sauer, Maximilian Merz, Elias Karl Mai, Carsten Müller-Tidow, Steffen Luntz, Anna Jauch, Peter Brossart, Martin Goerner, Stefan Klein, Bertram Glass, Peter Reimer, Ullrich Graeven, Roland Fenk, Mathias Haenel, Ivana von Metzler, Hans W. Lindemann, Christof Scheid, Igor-Wolfgang Blau, Hans J. Salwender, Richard Noppeney, Britta Besemer, Katja C. Weisel, Hartmut Goldschmidt
Journal: Blood
Blood (2025) 145 (16): 1780–1787.
https://doi.org/10.1182/blood.2024027342
Published: 2025
Includes: Supplemental data
Journal Articles

GSI: myeloma—cold case closed?

Free
Maximilian Merz, Nico Gagelmann
Journal: Blood
Blood (2025) 145 (2): 148–149.
https://doi.org/10.1182/blood.2024027056
Published: 2025
Journal Articles

Persistent Thrombocytopenia and Neutropenia Are Associated with Increased Mortality in Patients Treated with Anti-BCMA CAR T Cells for Relapsed/Refractory Multiple Myeloma

Free
Thomas C Wiemers, David Fandrei, Sabine Seiffert, Michael Rade, Susanne Rieprecht, Patrick Born, Markus Kreuz, Luise Fischer, Ronny Baber, Song Yau Wang, Enrica Bach, Sandra Hoffmann, Klaus H Metzeler, Marco Herling, Madlen Jentzsch, Georg-Nikolaus Franke, Ulrike Köhl, Maik Friedrich, Andreas Boldt, Kristin Reiche, Uwe Platzbecker, Vladan Vucinic, Maximilian Merz
Journal: Blood
Blood (2024) 144 (Supplement 1): 7095.
https://doi.org/10.1182/blood-2024-202101
Published: 2024
Journal Articles

Prevalence and Mutational Make-up of Secondary Hematologic Neoplasms in Multiple Myeloma Patients after CAR-T Cell Therapy

Free
Johannes Waldschmidt, Maximilian Merz, Judith S. Hecker, Franz Reinhard, Benjamin GT Shibru, Marion Hoegner, Anna Gebauer, David Fandrei, Manja Meggendorfer, Marietta Truger, Johannes Jung, Daniel Teschner, Max S. Topp, Anna Purcarea, Vladan Vucinic, Martin K. Kortüm, Torsten Haferlach, Florian Bassermann, Uwe Platzbecker, Hermann Einsele, Claudia Haferlach, Klaus H Metzeler, Katharina S. S. Götze, Leo Rasche
Journal: Blood
Blood (2024) 144 (Supplement 1): 4688.
https://doi.org/10.1182/blood-2024-210233
Published: 2024
Journal Articles

CT-Based Muscle Quality and Visceral Obesity Prior to Allogeneic Hematopoietic Stem Cell Transplantation Is of Prognostic Relevance in Patients with Acute Myeloid Leukemia

Free
Jule Ussmann, Clara Wall, Lara Bischof, Jacob Jendro, Dominic Brauer, Donata Backhaus, Klaus H Metzeler, Marco Herling, Carmen Herling, Vladan Vucinic, Georg-Nikolaus Franke, Maximilian Merz, Timm Denecke, Uwe Platzbecker, Sebastian Schwind, Hans-Jonas Meyer, Madlen Jentzsch
Journal: Blood
Blood (2024) 144 (Supplement 1): 2158.
https://doi.org/10.1182/blood-2024-199943
Published: 2024
Journal Articles

Cellular Composition and Clinical Factors Influencing Manufacturing Outcomes for Anti-BCMA CAR T Cell Therapy in a Large Real-World Cohort of Relapsed/Refractory Multiple Myeloma

Free
Vladan Vucinic, David Fandrei, Janine Kirchberg, Enrica Bach, Mandy Brueckner, Kathleen Friedrich, Carmen Herling, Madlen Jentzsch, Georg-Nikolaus Franke, Simone Heyn, Uwe Platzbecker, Maximilian Merz
Journal: Blood
Blood (2024) 144 (Supplement 1): 2094.
https://doi.org/10.1182/blood-2024-207117
Published: 2024
Journal Articles

Impact of Clonal Heterogeneity in Newly Diagnosed, Transplant-Eligible Multiple Myeloma - Subgroup Analysis of the GMMG HD6 Phase III Trial

Free
Maximilian Merz, Ema Pozek, Kaya Miah, Uta Bertsch, Britta Besemer, Mathias Hänel, Julia Krzykalla, Roland Fenk, Jana Schlenzka, Markus Munder, Christine Hanoun, Christoph Mann, Niels Weinhold, Christof Scheid, Roland Schroers, Igor Wolfgang Blau, Stefanie Huhn, Dirk Hose, Anna Jauch, Christina Kunz, Ivana von Metzler, Aneta Schieferdecker, Jörg Thomalla, Peter Reimer, Rolf Mahlberg, Ullrich Graeven, Stephan Kremers, Uwe Martens, Manfred Hensel, Axel Benner, Andrea Seidel-Glätzer, Katja C. Weisel, Marc S. Raab, Hans Salwender, Hartmut Goldschmidt, Elias K. Mai
Journal: Blood
Blood (2024) 144 (Supplement 1): 84.
https://doi.org/10.1182/blood-2024-201972
Published: 2024
Journal Articles

Predicting Progression Events in Multiple Myeloma from Routine Blood Work

Free
Maximilian Ferle, Nora Grieb, Markus Kreuz, Uwe Platzbecker, Thomas Neumuth, Kristin Reiche, Alexander Oeser, Maximilian Merz
Journal: Blood
Blood (2024) 144 (Supplement 1): 7476.
https://doi.org/10.1182/blood-2024-192951
Published: 2024
Journal Articles

Efficacy of Anti-BCMA CAR-T Cell Therapies in Multiple Myeloma Patients with Prior Exposure to Bispecific Antibodies- Results from a Retrospective Multi-Center Registry Analysis

Free
Johannes Waldschmidt, David Fandrei, Vladan Vucinic, Ralph Wäsch, Axel Nogai, Winfried Alsdorf, Annamaria Brioli, Evgenii Shumilov, Fabian Mueller, Raphael Teipel, Nico Gagelmann, Monika Engelhardt, Jan Krönke, Julia Mersi, Michael Hudecek, Martin K. Kortüm, Uwe Platzbecker, Hermann Einsele, Max S. Topp, Leo Rasche, Maximilian Merz
Journal: Blood
Blood (2024) 144 (Supplement 1): 2007.
https://doi.org/10.1182/blood-2024-210451
Published: 2024
Journal Articles

Cilta-Cel Is Associated with Improved Outcomes and Distinct Cellular Dynamics Compared with Ide-Cel for Relapsed or Refractory Multiple Myeloma

Free
Nico Gagelmann, Friedrich Stölzel, Roland Fenk, Tobias A.W. Holderried, Fabian Mueller, Natalia Tovar, Aina Oliver-Caldés, Kristin Rathje, Vladan Vucinic, Soraya Kharboutli, Ben-Niklas Bärmann, Francis A. Ayuk, Uwe Platzbecker, Anca Maria Albici, Natalie Schub, Friederike Schmitz, Cyrus Khandanpour, Marcel Teichert, Barbara Jeker, Nicolaus Kroeger, Bastian von Tresckow, Carlos Fernandez de Larrea, Thomas Pabst, Maximilian Merz
Journal: Blood
Blood (2024) 144 (Supplement 1): 2003.
https://doi.org/10.1182/blood-2024-211410
Published: 2024
Journal Articles

Measurable Residual Disease Detection of IDH1 or IDH2 Mutations Post but Not Prior to Allogeneic Hematopoietic Stem Cell Transplantation Show High Prognostic Relevance in Patients with Acute Myeloid Leukemia

Free
Jacob Jendro, Lara Bischof, Jule Ussmann, Tung Pham Thanh, Donata Backhaus, Dominic Brauer, Vladan Vucinic, Carmen Herling, Marco Herling, Georg-Nikolaus Franke, Maximilian Merz, Klaus H Metzeler, Uwe Platzbecker, Sebastian Schwind, Madlen Jentzsch
Journal: Blood
Blood (2024) 144 (Supplement 1): 4334.
https://doi.org/10.1182/blood-2024-207490
Published: 2024
Journal Articles

Prognostic Value of Baseline and Early Response FDG-PET/CT Combined with Cellular Dynamics in Patients with Refractory and Relapsed Mantle Cell Lymphoma (MCL) Undergoing Chimeric Antigen Receptor (CAR)-T Cell Therapy

Free
Simon M Krauß, Sabine Seiffert, Carmen Perez Fernandez, Thomas Walter Georgi, Janine Kirchberg, Enrica Bach, Mandy Brueckner, Madlen Jentzsch, Carmen Herling, Maximilian Merz, Klaus H Metzeler, Marco Herling, Georg-Nikolaus Franke, Andreas Boldt, Solveig Tiepolt, Regine Kluge, Ulrike Koehl, Timm Denecke, Osama Sabri, Ulrich Sack, Uwe Platzbecker, Lars Kurch, Vladan Vucinic
Journal: Blood
Blood (2024) 144 (Supplement 1): 6343.
https://doi.org/10.1182/blood-2024-206686
Published: 2024