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Tobias A.W. Holderried
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Journal Articles

Isatuximab, Lenalidomide, Bortezomib and Dexamethasone Induction Therapy for Transplant-Eligible Patients with Newly Diagnosed Multiple Myeloma: Final Progression-Free Survival Analysis of Part 1 of an Open-Label, Multicenter, Randomized, Phase 3 Trial (GMMG-HD7)

Free
Hartmut Goldschmidt, Uta Bertsch, Ema Pozek, Axel Benner, Roland Fenk, Britta Besemer, Christine Hanoun, Roland Schroers, Ivana von Metzler, Mathias Hänel, Christoph Mann, Lisa Leypoldt, Bernhard Heilmeier, Stefanie Huhn, Sabine Vogel, Michael Hundemer, Christof Scheid, Igor Wolfgang Blau, Steffen Luntz, Tobias A.W. Holderried, Karolin Trautmann-Grill, Deniz Gezer, Maika Klaiber-Hakimi, Martin Mueller, Evgenii Shumilov, Wolfgang Knauf, Christian Sebastian Michel, Thomas Geer, Hendrik Riesenberg, Christoph Lutz, Marc-Steffen Raab, Martin Hoffmann, Katja C. Weisel, Hans Salwender, Elias K. Mai
Journal: Blood
Blood (2024) 144 (Supplement 1): 769.
https://doi.org/10.1182/blood-2024-193308
Published: 2024
Journal Articles

Active Immunotherapy with Vididencel As Maintenance Treatment in MRD+ AML Patients in CR1 Results in Strong Anti-Tumor Immune Responses and Durable Long-Term Survival in Patients with an Immune Competent Immune Profile

Free
Arjan A. van de Loosdrecht, Eva-Maria Wagner Drouet, Uwe Platzbecker, Tobias A.W. Holderried, Catharina Van Elssen, Aristoteles Giagounidis, Soren Lehmann, Jacqueline Cloos, Hester Van Zeeburg, Jeroen Rovers, Bjorn T. Gjertsen
Journal: Blood
Blood (2024) 144 (Supplement 1): 2875.
https://doi.org/10.1182/blood-2024-201374
Published: 2024
Journal Articles

Cilta-Cel Is Associated with Improved Outcomes and Distinct Cellular Dynamics Compared with Ide-Cel for Relapsed or Refractory Multiple Myeloma

Free
Nico Gagelmann, Friedrich Stölzel, Roland Fenk, Tobias A.W. Holderried, Fabian Mueller, Natalia Tovar, Aina Oliver-Caldés, Kristin Rathje, Vladan Vucinic, Soraya Kharboutli, Ben-Niklas Bärmann, Francis A. Ayuk, Uwe Platzbecker, Anca Maria Albici, Natalie Schub, Friederike Schmitz, Cyrus Khandanpour, Marcel Teichert, Barbara Jeker, Nicolaus Kroeger, Bastian von Tresckow, Carlos Fernandez de Larrea, Thomas Pabst, Maximilian Merz
Journal: Blood
Blood (2024) 144 (Supplement 1): 2003.
https://doi.org/10.1182/blood-2024-211410
Published: 2024
Journal Articles

Sequential Dosing of Next-Generation IMA203CD8 TCR-T-Cell Therapy Targeting PRAME in Combination with BRAF-/MEK-Inhibition in a Melanoma Patient with Progressive Disease - a Case Report

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Friederike Schmitz, Martin Schumacher, Annkristin Heine, Annette Busch, Mario Heine, Julian A. Luetkens, Jennifer Landsberg, Niklas Schäfer, Oliver Ebert, Robert Zeiser, John G. Gribben, Peter Brossart, Tobias A.W. Holderried
Journal: Blood
Blood (2024) 144 (Supplement 1): 7194.
https://doi.org/10.1182/blood-2024-194461
Published: 2024
Journal Articles

Decreased Chronic GvHD with Post-Transplant Cyclophosphamide (PTCY) Compared to ATG in Patients with Myelofibrosis Allografted with Unrelated Donor: A Study from the Chronic Malignancies Working Party of the EBMT

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Yves Chalandon, Edouard F. Bonneville, Liesbeth C. de Wreede, Linda Koster, Joe Tuffnell, Jakob Passweg, Johannes Schetelig, Uwe Platzbecker, Ibrahim Yakoub-Agha, Urpu Salmenniemi, Mareike Verbeek, Moniek De Witte, Jean-Baptiste Méar, John Snowden, Tobias A.W. Holderried, Gwendolyn Van Gorkom, Frederic Baron, Marie Robin, Xavier Poiré, Mieke Roeven, Maija Itälä-Remes, Jan Maciej Zaucha, Kavita K Raj, Joanna Drozd-Sokolowska, Giorgia Battipaglia, Nicola Polverelli, Tomasz Czerw, Juan Carlos Hernandez Boluda, Donal P McLornan
Journal: Blood
Blood (2024) 144 (Supplement 1): 4894.
https://doi.org/10.1182/blood-2024-203487
Published: 2024
Journal Articles

Estimating the Impact on Survival of Not Receiving CAR T Therapy Despite Being Eligible in Relapsed or Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL) Patients in Germany

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Veit L. Buecklein, Francis A. Ayuk, Tobias A.W. Holderried, Christine Mai, Bradley Kievit, Rob Blisset, Brett Doble, Geoff Reid, Laura Reimeir, Caroline Bruns, Sachin Vadgama
Journal: Blood
Blood (2024) 144 (Supplement 1): 5037.
https://doi.org/10.1182/blood-2024-205589
Published: 2024
Journal Articles

Prognostic Impact of t(9;11) and Del(7q) As Intermediate-Risk Abnormalities in AML Following Allo-Transplant: Insights from the ELN 2022 Classification - an EBMT ALWP Study

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Iman Abou Dalle, Jaques-Emmanuel Galimard, Ali Bazarbachi, Gerard Socie, Patrice Chevallier, Peter Dreger, Gitte Olesen, Ibrahim Yakoub-Agha, Jurjen Versluis, Jurgen Kuball, Igor Wolfgang Blau, Hélène Labussière-Wallet, Thomas Heinicke, Dominik Schneidawind, Tobias A.W. Holderried, Keith Wilson, Thomas Schroeder, Frederic Baron, Eolia Brissot, Jordi Esteve, Arnon Nagler, Mohamad Mohty, Fabio Ciceri
Journal: Blood
Blood (2024) 144 (Supplement 1): 4945.
https://doi.org/10.1182/blood-2024-204824
Published: 2024
Journal Articles

Impact of Minimal Residual Disease on Progression-Free Survival in Patients with Newly Diagnosed Multiple Myeloma Treated with Isatuximab, Lenalidomide, Bortezomib and Dexamethasone Induction Therapy in the Phase 3 GMMG-HD7 Trial

Free
Elias K. Mai, Hans Salwender, Michael Hundemer, Uta Bertsch, Ema Pozek, Axel Benner, Roland Fenk, Britta Besemer, Christine Hanoun, Roland Schroers, Ivana von Metzler, Mathias Hänel, Christoph Mann, Lisa Leypoldt, Bernhard Heilmeier, Stefanie Huhn, Sabine Vogel, Christof Scheid, Igor Wolfgang Blau, Steffen Luntz, Niels Weinhold, Tobias A.W. Holderried, Karolin Trautmann-Grill, Deniz Gezer, Maika Klaiber-Hakimi, Martin Mueller, Evgenii Shumilov, Wolfgang Knauf, Christian Sebastian Michel, Thomas Geer, Hendrik Riesenberg, Christoph Lutz, Marc S. Raab, Martin Hoffmann, Katja C. Weisel, Hartmut Goldschmidt
Journal: Blood
Blood (2024) 144 (Supplement 1): 364.
https://doi.org/10.1182/blood-2024-194768
Published: 2024
Journal Articles

Induction of Cellular and Humoral Immune Responses Is Associated with Durable Remissions in MRD+ AML-Patients after Maintenance Treatment with an Allogeneic Leukemia-Derived Dendritic Cell Vaccine

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Arjan A. van de Loosdrecht, Eva Wagner Drouet, Uwe Platzbecker, Tobias A.W. Holderried, Catharina Van Elssen, Aristoteles Giagounidis, Soren Lehmann, Hester Van Zeeburg, Jeroen Rovers, Bjorn T. Gjertsen
Journal: Blood
Blood (2023) 142 (Supplement 1): 769.
https://doi.org/10.1182/blood-2023-185532
Published: 2023
Journal Articles

Vaccination Using an Allogeneic Leukemia-Derived Dendritic Cell Vaccine, Maintains and Improves Frequencies of Circulating Antigen Presenting Dendritic Cells Correlating with Relapse Free and Overall Survival in AML Patients

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Hester Van Zeeburg, Eva Wagner Drouet, Uwe Platzbecker, Tobias A.W. Holderried, Catharina Van Elssen, Aristoteles Giagounidis, Soren Lehmann, Jeroen Rovers, Bjorn T. Gjertsen, Arjan A. van de Loosdrecht
Journal: Blood
Blood (2023) 142 (Supplement 1): 2957.
https://doi.org/10.1182/blood-2023-188573
Published: 2023
Journal Articles

Use of an Allogeneic Leukemia-Derived Dendritic Cell Vaccine in MRD+ AML-Patients Results in MRD Conversion, Improved Relapse-Free Survival and Vaccine Induced Immune Responses to Tumor Antigens

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Arjan A. Van de Loosdrecht, Jacqueline Cloos, Eva-Maria Wagner-Drouet, Uwe Platzbecker, Tobias A.W. Holderried, Catharina van Elssen, Aristoteles Giagounidis, Sören Lehmann, Hester J.T. van Zeeburg, Jeroen Rovers, Bjorn T. Gjertsen
Journal: Blood
Blood (2022) 140 (Supplement 1): 1714–1715.
https://doi.org/10.1182/blood-2022-162169
Published: 2022
Journal Articles

The Potential of E-Health in Patients after Allogeneic Stem Cell Transplantation

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Friederike Schmitz, Charlotte Neuerburg, Martin Schumacher, Udo Holtick, Edgar Jost, Guido Kobbe, Ben-Niklas Bärmann, Marie-Therese Schmitz, Matthias Schmid, Peter Brossart, Martin Holderried, Tobias A.W. Holderried
Journal: Blood
Blood (2022) 140 (Supplement 1): 7966–7967.
https://doi.org/10.1182/blood-2022-160320
Published: 2022
Journal Articles

Induction of a Systemic Immune Response during Use of an Allogenic Leukemia-Derived Dendritic Cell Vaccine in MRD+ AML Patients Correlates with Clinical Response and MRD Conversion

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Arjan A. Van de Loosdrecht, Jacqueline Cloos, Eva-Maria Wagner-Drouet, Uwe Platzbecker, Tobias A.W. Holderried, Catharina van Elssen, Aristoteles Giagounidis, Marij J.P. Welters, Sjoerd H. van der Burg, Hester J.T. van Zeeburg, Jeroen Rovers, Bjorn T. Gjertsen
Journal: Blood
Blood (2022) 140 (Supplement 1): 3410–3411.
https://doi.org/10.1182/blood-2022-163116
Published: 2022
Journal Articles

Human CD8 + Treg after Allogeneic Stem-Cell Transplantation

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Tobias A.W. Holderried, MD, Pia Sauerborn, Hye-Jung Kim, PhD, Harvey Cantor, MD, Dominik Wolf, MD, Peter Brossart, MD
Journal: Blood
Blood (2016) 128 (22): 2243.
https://doi.org/10.1182/blood.V128.22.2243.2243
Published: 2016
Journal Articles

Immunotherapy With RNA Vaccination Coding For TAA In Renal Cell Carcinoma: Update On Immunological Responses and Correlation With Survival

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Susanne M Rittig, MD, Maik Häntschel, MD, Katrin J Weimer, MD, Annkristin Heine, MD, Martin R Müller, MD, PhD, Wolfram Brugger, MD, Marius Horger, MD, Olga Maksimovic, MD, Arnulf Stenzl, MD, Ingmar Hoerr, Hans-Georg Rammensee, Tobias A.W. Holderried, MD, Lothar Kanz, MD, Steve Pascolo, Peter Brossart, MD
Journal: Blood
Blood (2013) 122 (21): 1040.
https://doi.org/10.1182/blood.V122.21.1040.1040
Published: 2013
Journal Articles

CD8 + Treg - From Mouse To Man

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Tobias A.W. Holderried, MD, Hye-Jung Kim, PhD, Philipp A Lang, MD, PhD, Harvey Cantor, MD
Journal: Blood
Blood (2013) 122 (21): 3474.
https://doi.org/10.1182/blood.V122.21.3474.3474
Published: 2013
Journal Articles

Releasing CD8 + Treg Mediated Suppresssion Enhances Anti-Viral Immune Response

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Tobias A.W. Holderried, MD, Hye-Jung Kim, PhD, Philipp A Lang, MD, PhD, Harvey Cantor, MD
Journal: Blood
Blood (2013) 122 (21): 2280.
https://doi.org/10.1182/blood.V122.21.2280.2280
Published: 2013
Journal Articles

A Mouse Model for Immunotherapeutic Reversal of Leukemia-Induced T Cell Dysfunction

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Alan G. Ramsay, PhD, Gullu Gorgun, PhD, Tobias A.W. Holderried, David Zahrieh, MS, Fenglong Liu, PhD, John Quackenbush, PhD, Carlo M. Croce, MD, John G. Gribben, MD, DSc
Journal: Blood
Blood (2008) 112 (11): 30.
https://doi.org/10.1182/blood.V112.11.30.30
Published: 2008
Journal Articles

CLL Cells in TCL1 Transgenic Mice Induce Similar Defects in CD4 and CD8 T Cells to Those Observed in Patients with CLL.

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Gullu Gorgun, PhD, Tobias A.W. Holderried, Rifca Ledieu, MD, David Zahrieh, MS, John G. Gribben, MD,DSc.
Journal: Blood
Blood (2005) 106 (11): 50.
https://doi.org/10.1182/blood.V106.11.50.50
Published: 2005
Journal Articles

Cell Contact with CLL Cells Induces Defects in T Cell Differentiation and Effector Pathways: Impact of Silencing Specific Cytokine Production.

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Tobias A.W. Holderried, Gullu Gorgun, PhD, John G. Gribben, MD DSc
Journal: Blood
Blood (2004) 104 (11): 955.
https://doi.org/10.1182/blood.V104.11.955.955
Published: 2004