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Journal Articles

Second primary malignancies in multiple myeloma: Incidence, survival and prognostic factors from a large single-center observational study

Free
Noriko Nishimura, Andriy Derkach, Kelly Barnett, Tala Shekarkhand, Issam Hamadeh, Heather Landau, Michael Scordo, Gunjan Shah, Roni Shouval, Ross Firestone, Sridevi Rajeeve, Francesco Maura, Hamza Hashmi, Maximillian Merz, Malin Hultcrantz, Neha Korde, Alexander Lesokhin, Sham Mailankody, Urvi Shah, Kylee Maclachlan, Carlyn Tan, Sergio Giralt, Saad Usmani, Hani Hassoun
Journal: Blood
Blood (2025) 146 (Supplement 1): 2213.
https://doi.org/10.1182/blood-2025-2213
Published: 2025
Journal Articles

Low dose tocilizumab for mitigation of cytokine release syndrome with bispecific antibodies in relapsed/refractory multiple myeloma

Free
Issam Hamadeh, Maximillian Merz, Andriy Derkach, Tala Shekarkhand, Alexander Lesokhin, Sham Mailankody, Malin Hultcrantz, Carlyn Tan, Hani Hassoun, Urvi Shah, Kylee Maclachlan, Sridevi Rajeeve, Hamza Hashmi, Francesco Maura, Ross Firestone, Alice Wang, Dhwani Patel, Michael Scordo, Gunjan Shah, Heather Landau, Sergio Giralt, Saad Usmani, Neha Korde
Journal: Blood
Blood (2025) 146 (Supplement 1): 2210.
https://doi.org/10.1182/blood-2025-2210
Published: 2025
Journal Articles

Trial in progress: A phase 1 study to evaluate the safety and preliminary efficacy of arlocabtagene autoleucel (arlo-cel), a GPRC5D-targeted chimeric antigen receptor (CAR) T cell therapy, in combination with mezigdomide (MEZI) in patients (pts) with relapsed/refractory multiple myeloma (RRMM)

Free
Susan Bal, Luciano Costa, Nizar Bahlis, Myo Htut, Omar Nadeem, Krina Patel, Scott Solomon, Jaclyn Davis, Ziyan Guo, Kevin Hsu, Hongxiang Hu, Krishna R. Juluri, Jessica Katz, Timothy Pulham, Safiyyah Ziyad, Sham Mailankody
Journal: Blood
Blood (2025) 146 (Supplement 1): 5807.
https://doi.org/10.1182/blood-2025-5807
Published: 2025
Journal Articles

Respiratory viral infections are a significant cause of morbidity during long-term follow-up after CAR T cell therapy: Analysis of 445 episodes

Free
Sigrun Einarsdottir, Maria Isabel Sotelo, Teng Fei, Dedipya Bhamidipati, Magdalena Corona, Silvia Escribano-Serrat, Lorenzo Falchi, Mika Geva, Marina Gomez-Llobell, Jabour Halloun, Malin Hultcrantz, Sapir Israeli, Hazim Khatib, Mini Kamboj, Sham Mailankody, Genovefa Papanicolaou, Lia Palomba, Jae Park, Sandeep Raj, Kai Rejeski, Jaime Sanz, Michael Scordo, Gilles Salles, Susan Seo, Gunjan Shah, Niveen Shibli, Swarn Arya, Yannis Valtis, Saad Usmani, Miguel-Angel Perales, Roni Shouval, Zainab Shahid
Journal: Blood
Blood (2025) 146 (Supplement 1): 4498.
https://doi.org/10.1182/blood-2025-4498
Published: 2025
Journal Articles

Functionally high-risk disease is associated with inferior outcomes after chimeric antigen receptor T-cell therapy for relapsed refractory multiple myeloma

Free
Tara Sebastian, Hamza Hashmi, Ross Firestone, Eric Jurgens, Sridevi Rajeeve, Tasmin Farzana, Maximilian Merz, Carlyn Tan, Kylee Maclachlan, Francesco Maura, Neha Korde, Hani Hassoun, Urvi Shah, Malin Hultcrantz, Heather Landau, Michael Scordo, Alexander Lesokhin, Andriy Derkach, David Nemirovsky, Sergio Giralt, Sham Mailankody, Saad Usmani
Journal: Blood
Blood (2025) 146 (Supplement 1): 2291.
https://doi.org/10.1182/blood-2025-2291
Published: 2025
Journal Articles

Final results of a multi-center phase 2 trial of isatuximab-lenalidomide in patients with high risk smoldering multiple myeloma (HRSMM)

Free
Sheeba Thomas, Elisabet Manasanch, Sundar Jagannath, Neha Korde, Hans Lee, David Berrios, Krina Patel, Swami Iyer, Sham Mailankody, Behrang Amini, Pei Lin, Zuzana Berkova, Donna Weber, Gregory Kaufman, Lei Feng, Michelle Hildebrandt, Linghua Wang, Sattva Neelapu, Robert Orlowski, Ola Landgren
Journal: Blood
Blood (2025) 146 (Supplement 1): 5834.
https://doi.org/10.1182/blood-2025-5834
Published: 2025
Journal Articles

Lenalidomide-related diarrhea is associated with gut microbiota dysbiosis and disruption of the bile acid pool

Free
Kevin Miller, Teng Fei, Ruben Ramos, Ana Catarina Gradissimo De Oliveira, Jennifer Haber, Minsu Jaun, Francesca Castro, Andriy Derkach, Issam Hamadeh, Kylee Maclachlan, Malin Hultcrantz, Hani Hassoun, Sham Mailankody, Sridevi Rajeeve, Francesco Maura, Maximillian Merz, Hamza Hashmi, Ross Firestone, Eric Jurgens, Gunjan Shah, Michael Scordo, Heather Landau, Jonathan Peled, Sergio Giralt, Neha Korde, Saad Usmani, Urvi Shah, Alexander Lesokhin
Journal: Blood
Blood (2025) 146 (Supplement 1): 2233.
https://doi.org/10.1182/blood-2025-2233
Published: 2025
Journal Articles

Daratumumab versus lenalidomide as maintenance therapy in newly diagnosed multiple myeloma – final results from a randomized investigator-initiated trial

Free
Sridevi Rajeeve, Andriy Derkach, Sean Devlin, Jeannen Santos, Anna Przemielewska, Tara Sood, Francesca Castro, Thomas Atkinson, Kylee Maclachlan, Hamza Hashmi, Carlyn Tan, Neha Korde, Malin Hultcrantz, Alexander Lesokhin, Hani Hassoun, Parastoo Dahi, Michael Scordo, David Chung, Heather Landau, Gunjan Shah, Ola Landgren, Sergio Giralt, Sham Mailankody, Saad Usmani, Urvi Shah
Journal: Blood
Blood (2025) 146 (Supplement 1): 2273.
https://doi.org/10.1182/blood-2025-2273
Published: 2025
Journal Articles

Respiratory syncytial virus (RSV) infection after CAR T-cell therapy

Free
Maria Isabel Sotelo, Sigrun Einarsdottir, Ofrat Beyar-Katz, Alexander Boardman, Silvia Escribano-Serrat, Teng Fei, Mika Geva, Marina Gomez-Llobell, Jabour Halloun, Hazim Khatib, Malin Hultcrantz, Jennifer Lue, Sham Mailankody, Genovefa Papanicolaou, Lia Palomba, Jae Park, Kai Rejeski, Jaime Sanz, Michael Scordo, Susan Seo, Gunjan Shah, Niveen Shibli, Saad Usmani, Judy Yan, Noriko Nishimura, Zainab Shahid, Miguel-Angel Perales, Roni Shouval, Mini Kamboj
Journal: Blood
Blood (2025) 146 (Supplement 1): 1079.
https://doi.org/10.1182/blood-2025-1079
Published: 2025
Journal Articles

Trial in progress: QUINTESSENTIAL—a phase 2 study of arlocabtagene autoleucel (arlo-cel) in patients with relapsed/refractory multiple myeloma (RRMM)

Free
Ciara Louise Freeman, Sarah Larson, Omar Nadeem, Nikhil Munshi, Shinsuke Iida, Sham Mailankody, Paola Neri, Tara Gregory, Julia Piasecki, Safiyyah Ziyad, Hongxiang Hu, Svenja Johanna Groeneveld, Sarah Johnston, Timothy Pulham, Sandy Wong, Jaclyn Davis, Susan Bal, Anupama Kumar, Krina Patel
Journal: Blood
Blood (2025) 146 (Supplement 1): 4079.
https://doi.org/10.1182/blood-2025-4079
Published: 2025
Journal Articles

Belantamab mafodotin, nirogacestat, and pomalidomide in patients with relapsed/refractory multiple myeloma

Free
Malin Hultcrantz, Hani Hassoun, Neha Korde, Carlyn Tan, Sergio Giralt, Alexander Lesokhin, Kylee Maclachlan, Dhwani Patel, Urvi Shah, Sridevi Rajeeve, Hamza Hashmi, Andriy Derkach, Ross Firestone, Linh Tran, Meredith Hyland, Kazunori Murata, Kevin Herrera, Karlo Perica, Saad Usmani, Sham Mailankody
Journal: Blood
Blood (2025) 146 (Supplement 1): 4060.
https://doi.org/10.1182/blood-2025-4060
Published: 2025
Journal Articles

Phase II trial of maintenance therapy with iberdomide after autologous hematopoietic cell transplant for patients with multiple myeloma previously treated with lenalidomide

Free
Natalia Tijaro Ovalle, Malin Hultcrantz, Khayla Leiva, Molly Hogan, Ambika Datta, Anjali Patel, Hamza Hashmi, Hani Hassoun, Neha Korde, Alexander Lesokhin, Kylee Maclachlan, Sham Mailankody, Sridevi Rajeeve, Urvi Shah, Carlyn Tan, Saad Usmani, David Chung, Heather Landau, Michael Scordo, Sergio Giralt, Gunjan Shah
Journal: Blood
Blood (2025) 146 (Supplement 1): 4048.
https://doi.org/10.1182/blood-2025-4048
Published: 2025
Journal Articles

Effectiveness of remote patient monitoring in enabling outpatient step-up dosing for bispecifics at a large academic cancer center in the USA

Free
Sridevi Rajeeve, Matt Wilkes, Nicole Zahradka, Maithili Deshpande, Alice Wang, Issam Hamadeh, Kelly Aliaga, Katie Jones, Kylee Maclachlan, Hamza Hashmi, Carlyn Tan, Malin Hultcrantz, Alexander Lesokhin, Hani Hassoun, Maximillian Merz, Francesco Maura, Parastoo Dahi, Michael Scordo, Heather Landau, Gunjan Shah, Sergio Giralt, Sham Mailankody, Felice Yang, Niodita Gupta-Werner, Tonya Le Blanc, Jessica Fowler, Shuchita Kaila, Saad Usmani, Neha Korde
Journal: Blood
Blood (2025) 146 (Supplement 1): 2751.
https://doi.org/10.1182/blood-2025-2751
Published: 2025
Journal Articles

First 20-patient safety and efficacy data from nexicart-2, the first u.S. trial of CAR-T in R/R light chain (AL) amyloidosis, nxc-201

Free
Heather Landau, Shahzad Raza, Aaron Rosenberg, Jeffrey Zonder, Raymond Comenzo, Vaishali Sanchorawala, Michaela Liedtke, Amandeep Godara, Michael Rosenzweig, Charlotte Hughes, Eugene Brailovski, Mehrdad Abedi, Sham Mailankody, Jae Park, David Marks, Sridevi Rajeeve, Jennifer Liu
Journal: Blood
Blood (2025) 146 (Supplement 1): 696.
https://doi.org/10.1182/blood-2025-696
Published: 2025
Journal Articles

Factors associated with remote healthcare utilization in MM patients undergoing autologous stem cell transplantation

Free
Molly Benson, Anna Howard, Isabel Concepcion, Andriy Derkach, Gunjan Shah, Michael Scordo, Heather Landau, Sergio Giralt, Malin Hultcrantz, Carlyn Tan, Sham Mailankody, Hani Hassoun, Hamza Hashmi, Sridevi Rajeeve, Urvi Shah, Neha Korde, Kylee Maclachlan, Francesco Maura, Alexander Lesokhin, Miguel-Angel Perales, David Chung, Saad Usmani, Ross Firestone
Journal: Blood
Blood (2025) 146 (Supplement 1): 2632.
https://doi.org/10.1182/blood-2025-2632
Published: 2025
Journal Articles

T-ICAHT: grading and prognostic impact of thrombocytopenia after CAR T-cell therapy

Open Access
Kai Rejeski, Jaime Sanz, Teng Fei, Monica S. Nair, Hamza Hashmi, Abraham Avigdor, Ofrat Beyar-Katz, Veit L. Bücklein, Kevin J. Curran, Sigrun Einarsdottir, Jonathan H. Esensten, Netta Glaubach, Noa Golan-Accav, Marina Gomez-Llobell, Iris Halamis, Orit Itzhaki, Frederick L. Locke, Sham Mailankody, Ronit Marcus, Marcela V. Maus, M. Lia Palomba, Jae H. Park, Marcelo Pasquini, Sandeep Raj, Sridevi Rajeeve, Gilles Salles, Michael Scordo, Gunjan L. Shah, Avichai Shimoni, Marion Subklewe, Tobias Tix, Saad Z. Usmani, Ori Valid, Yannis K. Valtis, Tsila Zuckerman, Nirali N. Shah, Miguel-Angel Perales, Roni Shouval
Journal: Blood
Blood (2025) 146 (7): 834–846.
https://doi.org/10.1182/blood.2025028833
Published: 2025
Includes: Supplemental data
Journal Articles

Impact of Absolute Lymphocyte Count at Pre-Apheresis and Pre-Lymphodepletion on Chimeric Antigen Receptor (CAR)-T Therapy Outcomes in Relapsed Refractory Multiple Myeloma (RRMM)

Free
Noriko Nishimura, Sham Mailankody, Samantha Brown, Sean M. Devlin, Bruno Almeida Costa, Tasmin Farzana, Eric M Jurgens, Ross S Firestone, Karthik Nath, David J. Chung, Heather J. Landau, Michael Scordo, Gunjan L. Shah, Roni Shouval, Hamza Hashmi, Hani Hassoun, Kylee H Maclachlan, Malin Hultcrantz, Neha Korde, Alexander M. Lesokhin, Urvi A. Shah, Carlyn Rose Tan, Sergio A. Giralt, Saad Z. Usmani, Sridevi Rajeeve
Journal: Blood
Blood (2024) 144 (Supplement 1): 1944.
https://doi.org/10.1182/blood-2024-208490
Published: 2024
Journal Articles

Real-World Safety and Early Efficacy of Talquetamab in Patients with Heavily-Pretreated Relapsed/Refractory Multiple Myeloma

Free
Bruno Almeida Costa, Carlyn Rose Tan, Tala Shekarkhand, Ross S Firestone, Eric M Jurgens, Kevin Miller, Alexander M. Lesokhin, Gunjan L. Shah, Neha Korde, Sridevi Rajeeve, David J. Chung, Heather J. Landau, Michael Scordo, Hani Hassoun, Kylee H Maclachlan, Urvi A. Shah, Malin Hultcrantz, Issam S. Hamadeh, Sergio Giralt, Sham Mailankody, Saad Z. Usmani, Hamza Hashmi
Journal: Blood
Blood (2024) 144 (Supplement 1): 7026.
https://doi.org/10.1182/blood-2024-206413
Published: 2024
Journal Articles

Defining the Rates of Cytokine Release Syndrome Associated with Talquetamab Step-up Doses

Free
Issam S. Hamadeh, Tala Shekarkhand, Colin Rueda, Ross S Firestone, Alice X Wang, Neha Korde, Malin Hultcrantz, Alexander M. Lesokhin, Sham Mailankody, Hani Hassoun, Urvi A. Shah, Kylee H Maclachlan, Sridevi Rajeeve, Hamza Hashmi, Gunjan L. Shah, Michael Scordo, David J. Chung, Heather J. Landau, Sergio A. Giralt, Saad Z. Usmani, Carlyn Rose Tan
Journal: Blood
Blood (2024) 144 (Supplement 1): 6990.
https://doi.org/10.1182/blood-2024-209891
Published: 2024
Journal Articles

Immune-MRD Status Informs Tumor-MRD Outcome Prognostication in Multiple Myeloma Patients on Lenalidomide Maintenance

Free
Ross S Firestone, Anish Kumar Simhal, Devin McAvoy, Eric M Jurgens, Juan-José Garcés, David Nemirovsky, Andriy Derkach, Kylee H Maclachlan, Malin Hultcrantz, Sham Mailankody, Urvi A. Shah, Carlyn Rose Tan, Neha Korde, Hani Hassoun, Sridevi Rajeeve, Hamza Hashmi, Heather J. Landau, Michael Scordo, Gunjan L. Shah, Sergio Giralt, Benjamin Diamond, Francesco Maura, Kinga K. Hosszu, David J. Chung, Ola Landgren, Saad Z. Usmani, Alexander M. Lesokhin
Journal: Blood
Blood (2024) 144 (Supplement 1): 672.
https://doi.org/10.1182/blood-2024-206646
Published: 2024