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Journal Articles

Targeting cell-surface VISTA expression on allospecific naïve T cells promotes tolerance

Blood (2025) 145 (15): 1687–1700.

https://doi.org/10.1182/blood.2024025884

Published: 2025

Includes: Supplemental data

Journal Articles

Deficiency of T follicular helper cell Tet3 DNA demethylation inhibits pathogenic IgG2c class switching and chronic GVHD

Michael C. Zaiken, Sujeong Jin, Cameron McDonald-Hyman, Christina Hartigan, Peter Sage, Keli L. Hippen, Brent H Koehn, Angela Panoskaltsis-Mortari, Megan J Riddle, Cindy Eide, Jakub Tolar, Geoffrey R Hill, Leo Luznik, Corey S. Cutler, Jerome Ritz, Leslie S Kean, Ageliki Tsagaratou, Anjana Rao, Bruce R Blazar

Blood blood.2024025036.

https://doi.org/10.1182/blood.2024025036

Published: 2025

Includes: Supplemental data

Journal Articles

Repurposing a novel anti-cancer RXR agonist to attenuate murine acute GVHD and maintain graft-versus-leukemia responses

Blood (2021) 137 (8): 1090–1103.

https://doi.org/10.1182/blood.2020005628

Published: 2021

Includes: Supplemental data

Journal Articles

In Vitro Induction of Human Regulatory T-Cells (iTregs) Using Conditions of Low Tryptophan Plus Kynurenines

Keli L. Hippen, PhD, Margaret L. MacMillan, MD, Amanda Lemire, BS, Asim Saha, PhD, Eric Hanse, Colin Lord, Ameeta Kelekar, PhD, Roddy S. O'Connor, PhD, James L. Riley, PhD, Carl H June, MD, Leslie Kean, MD PhD, Jeffrey S. Miller, MD, John E. Wagner, MD, David H. Munn, MD, Bruce R. Blazar, MD

Blood (2016) 128 (22): 1229.

https://doi.org/10.1182/blood.V128.22.1229.1229

Published: 2016

Journal Articles

miR-146b antagomir–treated human Tregs acquire increased GVHD inhibitory potency

Yunjie Lu, Keli L. Hippen, Amanda L. Lemire, Jian Gu, Weizhi Wang, Xuhao Ni, Parvathi Ranganathan, Bruce L. Levine, James L. Riley, Carl H. June, Laurence A. Turka, David H. Munn, Ramiro Garzon, Ling Lu, Bruce R. Blazar

Blood (2016) 128 (10): 1424–1435.

https://doi.org/10.1182/blood-2016-05-714535

Published: 2016

Includes: Supplemental data

Journal Articles

Umbilical cord blood–derived T regulatory cells to prevent GVHD: kinetics, toxicity profile, and clinical effect

Claudio G. Brunstein, Jeffrey S. Miller, David H. McKenna, Keli L. Hippen, Todd E. DeFor, Darin Sumstad, Julie Curtsinger, Michael R. Verneris, Margaret L. MacMillan, Bruce L. Levine, James L. Riley, Carl H. June, Chap Le, Daniel J. Weisdorf, Philip B. McGlave, Bruce R. Blazar, John E. Wagner

Blood (2016) 127 (8): 1044–1051.

https://doi.org/10.1182/blood-2015-06-653667

Published: 2016

Includes: Supplemental data

Journal Articles

Megatal, Crispr/Cas9, and Talen T-Cell Receptor Gene Editing

Mark J. Osborn, PhD, Beau R Webber, PhD, Friederike Knipping, Cara-lin Lonetree, Anthony DeFeo, Amber McElroy, Colby Starker, PhD, Richard Gabriel, Sarah Merkel, Keli L. Hippen, PhD, Daniel Voytas, PhD, Christof von Kalle, MD, Manfred Schmidt, PhD, Jeffrey S. Miller, MD, Jordan Jarjour, PhD, Alexander Astrakhan, PhD, Andrew M Scharenberg, MD, Jakub Tolar, MD, PhD, Bruce R. Blazar, MD

Blood (2015) 126 (23): 2045.

https://doi.org/10.1182/blood.V126.23.2045.2045

Published: 2015

Journal Articles

Protein Kinase C-Theta Interacts with mTORC2 and Vimentin to Limit Regulatory T-Cell Function

Cameron McDonald-Hyman, BA, Govindarajan Thangavelu, PhD, James Muller, Guoan Zhang, PhD, Sudha Kumari, PhD, Asim Saha, PhD, Brent H. Koehn, PhD, Jason S. Mitchell, PhD, Brian T Fife, PhD, Jonathan S. Serody, MD, Mark J. Osborn, PhD, Keli L. Hippen, PhD, Ameeta Kelekar, PhD, David H. Munn, MD, Amnon Altman, PhD, Thomas A. Neubert, PhD, Michael L. Dustin, PhD, Bruce R. Blazar, MD

Blood (2015) 126 (23): 849.

https://doi.org/10.1182/blood.V126.23.849.849

Published: 2015

Journal Articles

Blocking IL-21 signaling ameliorates xenogeneic GVHD induced by human lymphocytes

Keli L. Hippen, Christoph Bucher, Dawn K. Schirm, Amanda M. Bearl, Ty Brender, Kathy A. Mink, Kimberly S. Waggie, Regis Peffault de Latour, Anne Janin, Julie M. Curtsinger, Stacey R. Dillon, Jeffrey S. Miller, Gerard Socie, Bruce R. Blazar

Blood (2012) 119 (2): 619–628.

https://doi.org/10.1182/blood-2011-07-368027

Published: 2012

Includes: Supplemental data

Journal Articles

Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics

Claudio G. Brunstein, Jeffrey S. Miller, Qing Cao, David H. McKenna, Keli L. Hippen, Julie Curtsinger, Todd DeFor, Bruce L. Levine, Carl H. June, Pablo Rubinstein, Philip B. McGlave, Bruce R. Blazar, John E. Wagner

Blood (2011) 117 (3): 1061–1070.

https://doi.org/10.1182/blood-2010-07-293795

Published: 2011

Includes: Supplemental data

Journal Articles

Adoptive Transfer of Umbilical Cord Blood (UCB)-Derived Regulatory T Cells (Tregs) to Recipients of Nonmyeloablative Unrelated Double UCB Transplantation.

Claudio Brunstein, Keli L. Hippen, David H. McKenna, Qing Cao, Julie Curtsinger, Darin Sumstad, Bruce L. Levine, PhD, James L. Riley, Carl H. June, MD, Jeffrey S. Miller, Bruce R. Blazar, John E. Wagner

Blood (2009) 114 (22): 513.

https://doi.org/10.1182/blood.V114.22.513.513

Published: 2009

Journal Articles

Umbilical cord blood regulatory T-cell expansion and functional effects of tumor necrosis factor receptor family members OX40 and 4-1BB expressed on artificial antigen-presenting cells

Keli L. Hippen, Paul Harker-Murray, Stephen B. Porter, Sarah C. Merkel, Aryel Londer, Dawn K. Taylor, Megan Bina, Angela Panoskaltsis-Mortari, Pablo Rubinstein, Nico Van Rooijen, Tatiana N. Golovina, Megan M. Suhoski, Jeffrey S. Miller, John E. Wagner, Carl H. June, James L. Riley, Bruce R. Blazar

Blood (2008) 112 (7): 2847–2857.

https://doi.org/10.1182/blood-2008-01-132951

Published: 2008

Includes: Supplemental data

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Targeting cell-surface VISTA expression on allospecific naïve T cells promotes tolerance

Deficiency of T follicular helper cell Tet3 DNA demethylation inhibits pathogenic IgG2c class switching and chronic GVHD

Repurposing a novel anti-cancer RXR agonist to attenuate murine acute GVHD and maintain graft-versus-leukemia responses

In Vitro Induction of Human Regulatory T-Cells (iTregs) Using Conditions of Low Tryptophan Plus Kynurenines

miR-146b antagomir–treated human Tregs acquire increased GVHD inhibitory potency

Umbilical cord blood–derived T regulatory cells to prevent GVHD: kinetics, toxicity profile, and clinical effect

Megatal, Crispr/Cas9, and Talen T-Cell Receptor Gene Editing

Protein Kinase C-Theta Interacts with mTORC2 and Vimentin to Limit Regulatory T-Cell Function

Blocking IL-21 signaling ameliorates xenogeneic GVHD induced by human lymphocytes

Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics

Adoptive Transfer of Umbilical Cord Blood (UCB)-Derived Regulatory T Cells (Tregs) to Recipients of Nonmyeloablative Unrelated Double UCB Transplantation.

Umbilical cord blood regulatory T-cell expansion and functional effects of tumor necrosis factor receptor family members OX40 and 4-1BB expressed on artificial antigen-presenting cells

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American Society of Hematology

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