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Journal Articles

Effect of avapritinib on skin lesions in patients with advanced systemic mastocytosis using a novel, artificial intelligence-based technology

Free
Deepti Radia, Tracy George, Ivan Alvarez-Twose, Francesco Mannelli, Michael Deininger, Kristen Pettit, Celalettin Ustun, Cristina Bulai Livideanu, Ingunn Dybedal, Elizabeth O. Hexner, Hui-Min Lin, Ilda Bidollari, Amber King, Saša Dimitrijević, Javier I. Muñoz-González, Brian D'Alessandro, Mira Patel, Anthony Melione, Jason Gotlib, Andreas Reiter, Daniel Deangelo, Frank Siebenhaar, Sigurd Broesby-Olsen, Karin Hartmann
Journal: Blood
Blood (2025) 146 (Supplement 1): 2030.
https://doi.org/10.1182/blood-2025-2030
Published: 2025
Journal Articles

Avapritinib achieves deep and durable symptom control with a well-tolerated safety profile in ism: Long-term outcomes from pioneer

Free
Tsewang Tashi, Hanneke Oude Elberink, Cem Akin, Mariana Castells, Jens Panse, Deepti Radia, Frank Siebenhaar, Cristina Bulai Livideanu, Karin Hartmann, Sigurd Broesby-Olsen, Tracy George, Vito Sabato, Paul van Daele, Sonia Cerquozzi, Ingunn Dybedal, Joseph Jurcic, Stéphane Barete, Andreas Reiter, Thanai Pongdee, Ruchi Desai, Philippe Schafhausen, Celalettin Ustun, Prithviraj Bose, Peter Vadas, Massimo Triggiani, Patrizia Bonadonna, Daniel Deangelo, Lindsay Rein, Pankit Vachhani, Ilda Bidollari, Hui-Min Lin, Janet Hong, Benjamin Lampson, Ashley Doyle, Ivan Alvarez-Twose, Jason Gotlib
Journal: Blood
Blood (2025) 146 (Supplement 1): 2024.
https://doi.org/10.1182/blood-2025-2024
Published: 2025
Journal Articles

Time from AML diagnosis to HCT and pre-HCT FLT3 inhibition impact pre-transplant MRD and benefit from post-HCT gilteritinib

Free
Mark Levis, Mehdi Hamadani, Brent Logan, Richard Jones, Anurag Singh, Mark Litzow, John Wingard, Esperanza Papadopoulos, Alexander Perl, Robert Soiffer, Celalettin Ustun, Masumi Ueda Oshima, Geoffrey Uy, Edmund Waller, Sumithira Vasu, Melhem Solh, Asmita Mishra, Lori Muffly, Heeje Kim, Matthias Stelljes, Yuho Najima, Masahiro Onozawa, Kirsty Thomson, Caroline Chen, Nahla Hasabou, Mathew Rosales, Jason Hill, Stanley Gill, Rishita Nuthethi, Denise King, Adam Mendizabal, Steven Devine, Mary Horowitz, Yi-Bin Chen
Journal: Blood
Blood (2025) 146 (Supplement 1): 1058.
https://doi.org/10.1182/blood-2025-1058
Published: 2025
Journal Articles

Effect of FLT3 maintenance in older FLT3-ITD+ adults undergoing allogeneic HCT. a post hoc analysis of BMT CTN 1506

Free
Sameem Abedin, Victor Baidoo, Aniko Szabo, Richard Jones, Anurag Singh, Mark Litzow, John Wingard, Esperanza Papadopoulos, Alexander Perl, Robert Soiffer, Celalettin Ustun, Masumi Ueda Oshima, Geoffrey Uy, Edmund Waller, Sumithira Vasu, Melhem Solh, Asmita Mishra, Lori Muffly, Heeje Kim, Matthias Stelljes, Yuho Najima, Masahiro Onozawa, Caroline Chen, Nahla Hasabou, Mathew Rosales, Jason Hill, Stanley Gill, Rishita Nuthethi, Denise King, Adam Mendizabal, Steven Devine, Mary Horowitz, Yi-Bin Chen, Mark Levis, Mehdi Hamadani
Journal: Blood
Blood (2025) 146 (Supplement 1): 170.
https://doi.org/10.1182/blood-2025-170
Published: 2025
Journal Articles

Efficacy and safety results from the primary analysis of the pivotal summit trial: Bezuclastinib in adults with non-advanced systemic mastocytosis

Free
Lindsay Rein, Nathan Boggs, Prithviraj Bose, Brian Modena, Vito Sabato, Karin Hartmann, Cem Akin, Tracy George, Cecilia Arana Yi, Hanneke Oude Elberink, Deepti Radia, Andreas Reiter, Miguel Piris-Villaespesa, Ingunn Dybedal, Jens Panse, Stephen Oh, Pankit Vachhani, Anthony Hunter, Mariana Castells, Cristina Bulai Livideanu, Paul van Daele, Arnold Kirshenbaum, Ivan Alvarez-Twose, Jennifer Vaughn, Minakshi Taparia, Sonia Cerquozzi, Andrzej Mital, Marek Hus, ALESSANDRA ROMANO, John Fahrenholz, Frederick Lansigan, Cristina Papayannidis, Helena Pomares, Michela Rondoni, Celalettin Ustun, Richard Herrscher, Michael Manning, Stéphane Barete, Mar Guilarte, Candido Rivera, Jonathan Bernstein, Peter Vadas, Chiara Elena, Derek McCulloch, Nina Orfali, Clodagh Keohane, Francesco Mannelli, Philippe Schafhausen, Amanda Pilla, Jenna Zhang, Lei Sun, Nisha Shah, Hina Jolin, Rachael Easton, Jessica Sachs, Frank Siebenhaar, Daniel Deangelo
Journal: Blood
Blood (2025) 146 (Supplement 1): 80.
https://doi.org/10.1182/blood-2025-80
Published: 2025
Journal Articles

Real-world outcomes of autologous CD19-directed CAR T-cell therapy in relapsed/refractory large B-cell lymphoma: A single-center experience

Free
Chen Zhang, Philip Papayanis, Parameswaran Venugopal, Celalettin Ustun, Sunita Nathan
Journal: Blood
Blood (2025) 146 (Supplement 1): 8056.
https://doi.org/10.1182/blood-2025-8056
Published: 2025
Journal Articles

Measurable residual disease and posttransplantation gilteritinib maintenance for patients with FLT3-ITD –mutated AML

Open Access
Clinical Trials & Observations
Mark J. Levis, Mehdi Hamadani, Brent R. Logan, Richard J. Jones, Anurag K. Singh, Mark R. Litzow, John R. Wingard, Esperanza B. Papadopoulos, Alexander E. Perl, Robert J. Soiffer, Celalettin Ustun, Masumi Ueda Oshima, Geoffrey L. Uy, Edmund K. Waller, Sumithira Vasu, Melhem Solh, Asmita Mishra, Lori S. Muffly, Hee-Je Kim, Matthias Stelljes, Yuho Najima, Masahiro Onozawa, Kirsty Thomson, Arnon Nagler, Andrew H. Wei, Guido Marcucci, Caroline Chen, Nahla Hasabou, Matt Rosales, Jason Hill, Stanley C. Gill, Rishita Nuthethi, Denise King, Adam Mendizabal, Steven M. Devine, Mary M. Horowitz, Yi-Bin Chen
Journal: Blood
Blood (2025) 145 (19): 2138–2148.
https://doi.org/10.1182/blood.2024025154
Published: 2025
Includes: Supplemental data
Journal Articles

Updated Efficacy and Safety Results of Patients Receiving Selected 100mg Bezuclastinib Dose and Participating in the Open-Label Extension of Summit: A Randomized, Double-Blind, Placebo Controlled Phase 2 Clinical Trial of Bezuclastinib in Adult Patients with Nonadvanced Systemic Mastocytosis

Free
Lindsay A.M. Rein, Daniel J. DeAngelo, Brian Modena, Stephen Oh, Bulai Livideanu Cridtina, Celalettin Ustun, Nathan Boggs, Michael Manning, Anthony M. Hunter, Cem Akin, Arnold Kirshenbaum, Ingunn Dybedal, Cecilia Y. Arana Yi, Richard Herrscher, Mariana Castells, Frederick Lansigan, Tracy I. George, Jay Patel, Lei Sun, Nisha Shah, Jenna Zhang, Amanda Pilla, Priya Singh, Marcus Carden, Frank Siebenhaar, Prithviraj Bose
Journal: Blood
Blood (2024) 144 (Supplement 1): 4556.
https://doi.org/10.1182/blood-2024-194551
Published: 2024
Journal Articles

Post-Hoc Analysis of Measurable Residual Disease from BMT-CTN 1506/Morpho: FLT3-ITD Variant Allele Frequency and Survival Are Highly Correlated

Free
Mark J. Levis, Mehdi Hamadani, Brent R. Logan, Richard J. Jones, Anurag K. Singh, Mark R. Litzow, John R. Wingard, Esperanza B. Papadopoulos, Alexander Perl, Robert J. Soiffer, Celalettin Ustun, Masumi Ueda Oshima, Geoffrey L Uy, Edmund K. Waller, Sumithira Vasu, Melhem M. Solh, Asmita Mishra, Lori S. Muffly, Hee-Je Kim, Matthias Stelljes, Yuho Najima, Masahiro Onozawa, Kirsty Thomson, Arnon Nagler, Andrew H. Wei, Guido Marcucci, Nahla Hasabou, Mathew Rosales, Jason Hill, Stanley C. Gill, Rishita Nuthethi, Denise King, Heather Wittsack, Adam Mendizabel, Steven M. Devine, Mary M. Horowitz, Yi-Bin Chen
Journal: Blood
Blood (2023) 142 (Supplement 1): 973.
https://doi.org/10.1182/blood-2023-177929
Published: 2023
Journal Articles

Gold is gold even in mud: NPM1 mutations in T-AML

Free
Celalettin Ustun
Journal: Blood
Blood (2023) 141 (15): 1784–1785.
https://doi.org/10.1182/blood.2022019295
Published: 2023
Journal Articles

Preliminary Safety and Efficacy from Apex, a Phase 2 Study of Bezuclastinib (CGT9486), a Novel, Highly Selective, Potent KIT D816V Tyrosine Kinase Inhibitor, in Adults with Advanced Systemic Mastocytosis (AdvSM)

Free
Daniel J. DeAngelo, Vinod A. Pullarkat, Miguel Piris-Villaespesa, Tracy I. George, Jay L. Patel, Celalettin Ustun, Prithviraj Bose, Mark L Heaney, Jessica Sachs, Lei Sun, Amanda Pilla, Benjamin Exter, Hina A. Jolin, Tsewang Tashi
Journal: Blood
Blood (2022) 140 (Supplement 1): 1512–1513.
https://doi.org/10.1182/blood-2022-156311
Published: 2022
Journal Articles

The Incidence and Impact of Clostridioides Difficile Infection (CDI) on Outcomes after Allogeneic Hematopoietic Cell Transplant (alloHCT) - a CIBMTR Study

Free
Muthalagu Ramanathan, Bipin B. Savani, Naya He, Soyoung Kim, Min Chen, Roy Chemaly, Christopher E Dandoy, Miguel-Angel Perales, Marcie L. Riches, Celalettin Ustun
Journal: Blood
Blood (2021) 138 (Supplement 1): 2894.
https://doi.org/10.1182/blood-2021-145774
Published: 2021
Journal Articles

Phase 2 Results of Urinary-Derived Human Chorionic Gonadotropin/Epidermal Growth Factor As Treatment for Life-Threatening Acute Gvhd

Free
Shernan G Holtan, Celalettin Ustun, Andrea Hoeschen, Julianne Feola, Qing Cao, Parth Gandhi, Wes Mosher, Chi Chen, Arne Slungaard, Armin Rashidi, Erica D. Warlick, Mukta Arora, Veronika Bachanova, Fiona He, Brian C. Betts, Gregory M. Vercellotti, Claudio G. Brunstein, Najla H El Jurdi, Ashish O. Gupta, Murali Janakiram, Joseph E. Maakaron, Angela Panoskaltsis-Mortari, Daniel J. Weisdorf, Margaret L. MacMillan
Journal: Blood
Blood (2021) 138 (Supplement 1): 261.
https://doi.org/10.1182/blood-2021-145008
Published: 2021
Journal Articles

The Impact of Non-Clinical Factors in Clinical Trial Enrollments of Patients with Hematologic Malignancies

Free
Jamile M. Shammo, Anne Timmermann, Deborah A. Katz, Agne Paner, Seo-Hyun Kim, Irene dehghan-Paz, Melissa L. Larson, Parameswaran Venugopal, Celalettin Ustun, Ankur Varma, Sunita Nathan
Journal: Blood
Blood (2021) 138 (Supplement 1): 1914.
https://doi.org/10.1182/blood-2021-148135
Published: 2021
Journal Articles

Non-Infectious Pulmonary Toxicity after Allogeneic Hematopoietic Cell Transplantation (HCT): A Center for International Blood and Marrow Transplant Research (CIBMTR) Study

Free
Sagar S. Patel, MD, Kwang Woo Ahn, PhD, Manoj Khanal, BS, MS, Caitrin Fretham, MPH, Celalettin Ustun, MD, Betty K. Hamilton, MD, Navneet S. Majhail, MD MS, Shin Mineishi, MD, Bipin N. Savani, MD, Mohamed Sorror, MD MSc, Edward A. Stadtmauer, MD FACP, Brent Logan, PhD, Marcelo C. Pasquini, MDMS, Saurabh Chhabra, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 7–8.
https://doi.org/10.1182/blood-2020-140503
Published: 2020
Journal Articles

Outcomes of COVID-19 Infection in Patients with Hematologic Malignancies

Free
Elizabeth Behrens, MD, Anne Timmermann, Alexander Yerkan, Deborah A. Katz, MD, Agne Paner, MD, Melissa C. Larson, MD, Seo-Hyun Kim, MD, Shivi Jain, MDMBBS, Sefer Gezer, MD, Parameswaran Venugopal, MD, Irene Dehghan-Paz, Yoona Rhee, Celalettin Ustun, MD, Ankur Varma, Jamile M. Shammo, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 20–21.
https://doi.org/10.1182/blood-2020-141063
Published: 2020
Journal Articles

Evaluation of Patients with PNH Treated By Eculizumab: Real World Data from Turkey

Free
Fatma Keklik Karadag, MD, Mustafa Nuri Yenerel, MD, Yılmaz Mehmet, MD, Hava uskudar Teke, MD, Vildan Ozkocaman, MD, Tulin Tuglular, MD, Fuat Erdem, MD, Ali Unal, MD, Orhan Ayyildiz, MD, Gulsum Ozet, MD, Melda Ozkan, MD, Emin Kaya, MD, Mesut Ayer, MD, Ozan Salim, MD, Birol Güvenç, MD, Hakan Ozdogu, MD, Özgür Mehtap, MD, Mehmet Sönmez, MD, Nil Güler, MD, Sibel Kabukcu Hacioglu, MD, Ismet Aydogdu, MD, Ozlen Bektas, MD, Selami Kocak Toprak, MD, Lale Kaynar, MD, Munci Yagci, MD, Salih Aksu, MDPROF., Anil Tombak, MD, Volkan Karakus, MD, Irfan Yavasoglu, MD, Birgül Öneç, MD, Mehmet Ali Özcan, MD, Levent Ündar, MD, Rıdvan Ali, MD, Celalettin Ustun, MD, Osman Ilhan, MD, Guray Saydam, MD, Fahri Sahin, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4805.
https://doi.org/10.1182/blood-2019-128743
Published: 2019
Journal Articles

Facilitating Resolution of Life-Threatening Acute Graft-Versus-Host Disease By Supplementation of Human Chorionic Gonadotropin and Epidermal Growth Factor (Pregnyl): A Phase I Study

Free
Shernan G. Holtan, MD, Andrea Hoeschen, Qing Cao, MS, Mukta Arora, MD, Veronika Bachanova, MD PhD, Claudio G Brunstein, MD PhD, Sarah Cooley, MD, Jeffrey S. Miller, MD, Arne Slungaard, MD, Celalettin Ustun, MD, Armin Rashidi, MD PhD, Gregory M Vercellotti, MD FACP, Erica D. Warlick, MD, Todd E. DeFor, MS, John E. Wagner, MD, Bruce R. Blazar, MD, Pamala A. Jacobson, PharmD, Angela Panoskaltsis-Mortari, PhD, Margaret L. MacMillan, MD, Daniel J. Weisdorf, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 71.
https://doi.org/10.1182/blood-2018-99-113564
Published: 2018
Journal Articles

Allogeneic Hematopoietic Cell Transplantation (HCT) Vs. Non-HCT Consolidation Therapies in Acute Myeloid Leukemia (AML) Patients 60-75 Years of Age in First Complete Remission (CR1): An Alliance (A151509), SWOG, ECOG-ACRIN and CIBMTR Study

Free
Celalettin Ustun, MD, Jennifer Le-Rademacher, PhD, Hai-Lin Wang, MPH, Megan Othus, Zhuoxin Sun, PhD, Brittny Major, Mei-Jie Zhang, PhD, Elizabeth Storrick, Jacqueline M Lafky, Selina Chow, Krzysztof Mrózek, MD PhD, Eyal C. Attar, MD, Clara D. Bloomfield, MD, Larry D Cripe, MD, Richard A. Larson, MD, Guido Marcucci, Gail J. Roboz, MD, Geoffrey L. Uy, MD, Richard M. Stone, MD, Aminah Jatoi, Thomas C. Shea, MD, Marcos de Lima, MD, James M. Foran, MD, Brenda M. Sandmaier, MD, Mark R. Litzow, MD, Harry P. Erba, MD PhD, Arti Hurria, MD, Daniel J. Weisdorf, MD, Andrew S Artz, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2170.
https://doi.org/10.1182/blood-2018-99-118383
Published: 2018
Journal Articles

First-in-human phase 1 clinical study of the IL-15 superagonist complex ALT-803 to treat relapse after transplantation

Free
Clinical Trials & Observations
Rizwan Romee, Sarah Cooley, Melissa M. Berrien-Elliott, Peter Westervelt, Michael R. Verneris, John E. Wagner, Daniel J. Weisdorf, Bruce R. Blazar, Celalettin Ustun, Todd E. DeFor, Sithara Vivek, Lindsey Peck, John F. DiPersio, Amanda F. Cashen, Rachel Kyllo, Amy Musiek, András Schaffer, Milan J. Anadkat, Ilana Rosman, Daniel Miller, Jack O. Egan, Emily K. Jeng, Amy Rock, Hing C. Wong, Todd A. Fehniger, Jeffrey S. Miller
Journal: Blood
Blood (2018) 131 (23): 2515–2527.
https://doi.org/10.1182/blood-2017-12-823757
Published: 2018
Includes: Supplemental data