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Apex Part 1: Updated Assessment of Bezuclastinib (CGT9486), a Selective KIT D816V Tyrosine Kinase Inhibitor, in Patients with Advanced Systemic Mastocytosis (AdvSM)

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Daniel J. DeAngelo, Jason Gotlib, Vinod Pullarkat, Pankit Vachhani, Tsewang Tashi, Stephanie Lee, Gary J. Schiller, Anthony M. Hunter, Miguel Piris-Villaespesa, Helena Pomares, Bulai Livideanu Cridtina, Khalid Shoumariyeh, Jonathan Lambert, Tracy I. George, Jay Patel, Cristina Papayannidis, Tania Jain, Michael W. Deininger, Andreas Reiter, Gabriela S. Hobbs, Lei Sun, Deepak Nagendra, Jenna Zhang, Amanda Pilla, Kim Dishman, Marcus Carden, Deepti H. Radia
Journal: Blood
Blood (2024) 144 (Supplement 1): 659.
https://doi.org/10.1182/blood-2024-193678
Published: 2024
Journal Articles

Updated Efficacy and Safety Results of Patients Receiving Selected 100mg Bezuclastinib Dose and Participating in the Open-Label Extension of Summit: A Randomized, Double-Blind, Placebo Controlled Phase 2 Clinical Trial of Bezuclastinib in Adult Patients with Nonadvanced Systemic Mastocytosis

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Lindsay A.M. Rein, Daniel J. DeAngelo, Brian Modena, Stephen Oh, Bulai Livideanu Cridtina, Celalettin Ustun, Nathan Boggs, Michael Manning, Anthony M. Hunter, Cem Akin, Arnold Kirshenbaum, Ingunn Dybedal, Cecilia Y. Arana Yi, Richard Herrscher, Mariana Castells, Frederick Lansigan, Tracy I. George, Jay Patel, Lei Sun, Nisha Shah, Jenna Zhang, Amanda Pilla, Priya Singh, Marcus Carden, Frank Siebenhaar, Prithviraj Bose
Journal: Blood
Blood (2024) 144 (Supplement 1): 4556.
https://doi.org/10.1182/blood-2024-194551
Published: 2024
Journal Articles

Apex Part 2 Trial in Progress: A Phase 2 Open-Label Clinical Study of Bezuclastinib in Adult Patients with Advanced Systemic Mastocytosis

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Isaac Goncalves, Stephen Fuller, Jason Gotlib, Pankit Vachhani, Vinod Pullarkat, Daniel J. DeAngelo, Saskia K. Klein, Wolfgang R. Sperr, Karin Hartmann, Khalid Shoumariyeh, Jens Panse, Teng Fong Ng, Miguel Piris-Villaespesa, Tsewang Tashi, Anthony M. Hunter, Prithviraj Bose, Cecilia Y. Arana Yi, Manish Jain, Helena Pomares, Tracy I. George, Jay Patel, Cristina Papayannidis, Minakshi S. Taparia, Bulai Livideanu Cridtina, Juliana Schwaab, Ingunn Dybedal, Jonathan Lambert, Tania Jain, Ewa Wierzbicka-Hainaut, Olivier Hermine, Massimiliano Bonifacio, Gabriela S. Hobbs, Michael W. Deininger, Amanda Pilla, Marcus Carden, Deepti H. Radia
Journal: Blood
Blood (2024) 144 (Supplement 1): 4569.1.
https://doi.org/10.1182/blood-2024-194550
Published: 2024