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B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor–transduced T cells
Free
Retrospective analysis of prognostic factors for angioimmunoblastic T-cell lymphoma: a multicenter cooperative study in Japan
Free
A prospective evaluation of degranulation assays in the rapid diagnosis of familial hemophagocytic syndromes
Free
Chelation use and iron burden in North American and British thalassemia patients: a report from the Thalassemia Longitudinal Cohort
Free
The characteristics and outcomes of parainfluenza virus infections in 200 patients with leukemia or recipients of hematopoietic stem cell transplantation
Free
Risk of complications during hematopoietic stem cell collection in pediatric sibling donors: a prospective European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party study
Free
Early matched sibling hematopoietic cell transplantation for adult AML in first remission using an age-adapted strategy: long-term results of a prospective GOELAMS study
Free
Transplantation in patients with SCID: mismatched related stem cells or unrelated cord blood?
Free
Costimulated tumor-infiltrating lymphocytes are a feasible and safe alternative donor cell therapy for relapse after allogeneic stem cell transplantation
Free
Issue Archive
March 22 2012
In this Issue
Table of Contents
Inside Blood
Blood Work
Plenary Paper
PLENARY PAPER
B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor–transduced T cells
Free
Clinical Trials & Observations
James N. Kochenderfer,Mark E. Dudley,Steven A. Feldman,Wyndham H. Wilson,David E. Spaner,Irina Maric,Maryalice Stetler-Stevenson,Giao Q. Phan,Marybeth S. Hughes,Richard M. Sherry,James C. Yang,Udai S. Kammula,Laura Devillier,Robert Carpenter,Debbie-Ann N. Nathan,Richard A. Morgan,Carolyn Laurencot,Steven A. Rosenberg
Perspectives
Review Article
Hematopoiesis and Stem Cells
Membrane-bound human SCF/KL promotes in vivo human hematopoietic engraftment and myeloid differentiation Free
Shinsuke Takagi,Yoriko Saito,Atsushi Hijikata,Satoshi Tanaka,Takashi Watanabe,Takanori Hasegawa,Shinobu Mochizuki,Jun Kunisawa,Hiroshi Kiyono,Haruhiko Koseki,Osamu Ohara,Takashi Saito,Shuichi Taniguchi,Leonard D. Shultz,Fumihiko Ishikawa
Engraftment of human HSCs in nonirradiated newborn NOD-scid IL2rγnull mice is enhanced by transgenic expression of membrane-bound human SCF Free
Michael A. Brehm,Waldemar J. Racki,Jean Leif,Lisa Burzenski,Vishnu Hosur,Amber Wetmore,Bruce Gott,Mary Herlihy,Ronald Ignotz,Raymond Dunn,Leonard D. Shultz,Dale L. Greiner
Immunobiology
B cell–intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice Free
Mike Recher,Siobhan O. Burns,Miguel A. de la Fuente,Stefano Volpi,Carin Dahlberg,Jolan E. Walter,Kristin Moffitt,Divij Mathew,Nadine Honke,Philipp A. Lang,Laura Patrizi,Hervé Falet,Marton Keszei,Masayuki Mizui,Eva Csizmadia,Fabio Candotti,Kari Nadeau,Gerben Bouma,Ottavia M. Delmonte,Francesco Frugoni,Angela B. Ferraz Fomin,David Buchbinder,Emma Maria Lundequist,Michel J. Massaad,George C. Tsokos,John Hartwig,John Manis,Cox Terhorst,Raif S. Geha,Scott Snapper,Karl S. Lang,Richard Malley,Lisa Westerberg,Adrian J. Thrasher,Luigi D. Notarangelo
Lymphoid Neoplasia
Retrospective analysis of prognostic factors for angioimmunoblastic T-cell lymphoma: a multicenter cooperative study in Japan
Free
Clinical Trials & Observations
Takashi Tokunaga,Kazuyuki Shimada,Kazuhito Yamamoto,Dai Chihara,Takuji Ichihashi,Rika Oshima,Mitsune Tanimoto,Toshihiro Iwasaki,Atsushi Isoda,Akira Sakai,Hikaru Kobayashi,Kunio Kitamura,Kosei Matsue,Masafumi Taniwaki,Sadahiro Tamashima,Yoshio Saburi,Taro Masunari,Tomoki Naoe,Shigeo Nakamura,Tomohiro Kinoshita
Disruption of BIRC3 associates with fludarabine chemorefractoriness in TP53 wild-type chronic lymphocytic leukemia Free
Davide Rossi,Marco Fangazio,Silvia Rasi,Tiziana Vaisitti,Sara Monti,Stefania Cresta,Sabina Chiaretti,Ilaria Del Giudice,Giulia Fabbri,Alessio Bruscaggin,Valeria Spina,Clara Deambrogi,Marilisa Marinelli,Rosella Famà,Mariangela Greco,Giulia Daniele,Francesco Forconi,Valter Gattei,Francesco Bertoni,Silvia Deaglio,Laura Pasqualucci,Anna Guarini,Riccardo Dalla-Favera,Robin Foà,Gianluca Gaidano
Myeloid Neoplasia
Phagocytes, Granulocytes, and Myelopoiesis
A prospective evaluation of degranulation assays in the rapid diagnosis of familial hemophagocytic syndromes
Free
Clinical Trials & Observations
Yenan T. Bryceson,Daniela Pende,Andrea Maul-Pavicic,Kimberly C. Gilmour,Heike Ufheil,Thomas Vraetz,Samuel C. Chiang,Stefania Marcenaro,Raffaella Meazza,Ilka Bondzio,Denise Walshe,Gritta Janka,Kai Lehmberg,Karin Beutel,Udo zur Stadt,Nadine Binder,Maurizio Arico,Lorenzo Moretta,Jan-Inge Henter,Stephan Ehl
Platelets and Thrombopoiesis
Red Cells, Iron, and Erythropoiesis
Chelation use and iron burden in North American and British thalassemia patients: a report from the Thalassemia Longitudinal Cohort
Free
Clinical Trials & Observations
Janet L. Kwiatkowski,Hae-Young Kim,Alexis A. Thompson,Charles T. Quinn,Brigitta U. Mueller,Isaac Odame,Patricia J. Giardina,Elliott P. Vichinsky,Jeanne M. Boudreaux,Alan R. Cohen,John B. Porter,Thomas Coates,Nancy F. Olivieri,Ellis J. Neufeld,for the Thalassemia Clinical Research Network
Thrombosis and Hemostasis
F8 gene mutation type and inhibitor development in patients with severe hemophilia A: systematic review and meta-analysis Free
Samantha C. Gouw,H. Marijke van den Berg,Johannes Oldenburg,Jan Astermark,Philip G. de Groot,Maurizio Margaglione,Arthur R. Thompson,Waander van Heerde,Jorien Boekhorst,Connie H. Miller,Saskia le Cessie,Johanna G. van der Bom
Transplantation
The characteristics and outcomes of parainfluenza virus infections in 200 patients with leukemia or recipients of hematopoietic stem cell transplantation
Free
CME
Roy F. Chemaly,Santosh S. Hanmod,Dhanesh B. Rathod,Shashank S. Ghantoji,Ying Jiang,Arpan Doshi,Karen Vigil,Javier A. Adachi,Andrew M. Khoury,Jeffery Tarrand,Chitra Hosing,Richard Champlin
Risk of complications during hematopoietic stem cell collection in pediatric sibling donors: a prospective European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party study
Free
Clinical Trials & Observations
Jan Styczynski,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,Adriana Balduzzi,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,Lidia Gil,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,Myriam Labopin,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,Rose-Marie Hamladji,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,Sarah Marktel,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,M. Akif Yesilipek,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,Franca Fagioli,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,Karoline Ehlert,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,Martina Matulova,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,Jean-Hugues Dalle,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,Jacek Wachowiak,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,Maurizio Miano,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,Chiara Messina,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,Miguel Angel Diaz,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,Christiane Vermylen,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,Matthias Eyrich,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,Isabel Badell,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,Peter Dreger,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,Jolanta Gozdzik,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,Daphna Hutt,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,Jelena Rascon,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,Giorgio Dini,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,Christina Peters,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party
Early matched sibling hematopoietic cell transplantation for adult AML in first remission using an age-adapted strategy: long-term results of a prospective GOELAMS study
Free
Clinical Trials & Observations
Bruno Lioure,on behalf of the GOELAMS,Marie C. Béné,on behalf of the GOELAMS,Arnaud Pigneux,on behalf of the GOELAMS,Anne Huynh,on behalf of the GOELAMS,Patrice Chevallier,on behalf of the GOELAMS,Nathalie Fegueux,on behalf of the GOELAMS,Didier Blaise,on behalf of the GOELAMS,Brigitte Witz,on behalf of the GOELAMS,Martine Delain,on behalf of the GOELAMS,Jérôme Cornillon,on behalf of the GOELAMS,Isabelle Luquet,on behalf of the GOELAMS,Odile Blanchet,on behalf of the GOELAMS,Pascale Cornillet-Lefebvre,on behalf of the GOELAMS,Martin Carré,on behalf of the GOELAMS,Mathilde Hunault,on behalf of the GOELAMS,Fabrice Larosa,on behalf of the GOELAMS,Thierry Lamy,on behalf of the GOELAMS,Edouard Randriamalala,on behalf of the GOELAMS,Mario Ojeda-Uribe,on behalf of the GOELAMS,Christian Berthou,on behalf of the GOELAMS,Luc Fornecker,on behalf of the GOELAMS,Jean-Luc Harousseau,on behalf of the GOELAMS,Didier Bouscary,on behalf of the GOELAMS,Norbert Ifrah,on behalf of the GOELAMS,Jean-Yves Cahn,on behalf of the GOELAMS
Transplantation in patients with SCID: mismatched related stem cells or unrelated cord blood?
Free
Clinical Trials & Observations
Juliana F. Fernandes,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,Vanderson Rocha,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,Myriam Labopin,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,Benedicte Neven,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,Despina Moshous,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,Andrew R. Gennery,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,Wilhelm Friedrich,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,Fulvio Porta,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,Cristina Diaz de Heredia,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,Donna Wall,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,Yves Bertrand,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,Paul Veys,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,Mary Slatter,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,Ansgar Schulz,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,Ka Wah Chan,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,Michael Grimley,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,Mouhab Ayas,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,Tayfun Gungor,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,Wolfram Ebell,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,Carmem Bonfim,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,Krzysztof Kalwak,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,Pierre Taupin,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,Stéphane Blanche,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,H. Bobby Gaspar,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,Paul Landais,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,Alain Fischer,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,Eliane Gluckman,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,Marina Cavazzana-Calvo,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation
Costimulated tumor-infiltrating lymphocytes are a feasible and safe alternative donor cell therapy for relapse after allogeneic stem cell transplantation
Free
Brief Report
Nancy M. Hardy,Vicki Fellowes,Jeremy J. Rose,Jeanne Odom,Stefania Pittaluga,Seth M. Steinberg,Bazetta Blacklock-Schuver,Daniele N. Avila,Sarfraz Memon,Roger J. Kurlander,Hahn M. Khuu,Maryalice Stetler-Stevenson,Esther Mena,Andrew J. Dwyer,Bruce L. Levine,Carl H. June,Ran Reshef,Robert H. Vonderheide,Ronald E. Gress,Daniel H. Fowler,Frances T. Hakim,Michael R. Bishop
Correspondence
Other Departments
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Cover Image
Cover Image
Knocking down filamins A and B resulted in the production of embryonic stem cell–derived proplatelets with abnormally large swellings and proplatelet shafts that generated giant platelets in culture. See the article by Kanaji et al on page 2906.
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