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Journal Articles

Antibiotic-induced loss of gut microbiome metabolic output correlates with clinical responses to CAR T-cell therapy

Available to Purchase
Clinical Trials & Observations
Rishika Prasad, Abdur Rehman, Lubna Rehman, Faezeh Darbaniyan, Viktoria Blumenberg, Maria-Luisa Schubert, Uria Mor, Eli Zamir, Sabine Schmidt, Tomo Hayase, Chia-Chi Chang, Lauren McDaniel, Ivonne Flores, Paolo Strati, Ranjit Nair, Dai Chihara, Luis E. Fayad, Sairah Ahmed, Swaminathan P. Iyer, Michael Wang, Preetesh Jain, Loretta J. Nastoupil, Jason Westin, Reetakshi Arora, Joel Turner, Fareed Khawaja, Ranran Wu, Jennifer B. Dennison, Meghan Menges, Melanie Hidalgo-Vargas, Kayla Reid, Marco L. Davila, Peter Dreger, Felix Korell, Anita Schmitt, Mark R. Tanner, Richard E. Champlin, Christopher R. Flowers, Elizabeth J. Shpall, Samir Hanash, Sattva S. Neelapu, Michael Schmitt, Marion Subklewe, Johannes Francois-Fahrmann, C. K. Stein-Thoeringer, Eran Elinav, Michael D. Jain, Eiko Hayase, Robert R. Jenq, Neeraj Y. Saini
Journal: Blood
Blood (2025) 145 (8): 823–839.
https://doi.org/10.1182/blood.2024025366
Published: 2025
Includes: Supplemental data
Journal Articles

Utilizing Synthetic Individual Patient Level Cohorts from Machine Learning on Clinical Trials to Define Endpoints for Bispecific Trials in Large B-Cell Lymphoma

Free
Dai Chihara, Micheal J. Kane, Christopher R. Flowers, Brian P. Hobbs
Journal: Blood
Blood (2024) 144 (Supplement 1): 4462.
https://doi.org/10.1182/blood-2024-193578
Published: 2024
Journal Articles

Comprehensive Characterization and Validation of the Tumor Microenvironment in Patients with Relapsed/Refractory Large B-Cell Lymphoma Identifies Subgroups with Greatest Benefit from CD19 CAR T-Cell Therapy

Free
Xubin Li, Kartik Singhal, Qing Deng, Dai Chihara, David A Russler-Germain, Usama Hussein, Jennifer Ann Foltz, Jared Henderson, Ashley Wilson, Evelyn Schmidt, Imran A. Nizamuddin, Tommy Dinh, Ryan Sun, Akhil Kesaraju, Laura K. Hilton, David W. Scott, Francisco Vega, Christopher R. Flowers, Obi Griffith, Todd A Fehniger, Malachi Griffith, Michael R. Green
Journal: Blood
Blood (2024) 144 (Supplement 1): 643.
https://doi.org/10.1182/blood-2024-204166
Published: 2024
Journal Articles

Survival Outcomes and Genetic Assessment in Patients with Dual Diagnoses of B-Cell and T-Cell Lymphomas

Free
Anath Lionel, Karmila Murphy, Amy A. Ayers, Christopher R. Flowers, Keyur P. Patel, Courtney D. DiNardo, Francisco Vega, Dai Chihara
Journal: Blood
Blood (2024) 144 (Supplement 1): 1680.
https://doi.org/10.1182/blood-2024-211432
Published: 2024
Journal Articles

Retreatment with R-CHOP-like Therapy Is Active with Durable Responses in Patients with Late Relapse of Diffuse Large B-Cell Lymphoma

Free
Eduardo Edelman Saul, Bryan Valcarcel, Amy A. Ayers, Mansoor Noorani, Dai Chihara, Fateeha Furqan, Sairah Ahmed, Swaminathan P Iyer, Sattva S. Neelapu, Luis E. Fayad, F. B. Hagemeister, Chijioke Nze, Preetesh Jain, Michael Wang, Paolo Strati, Ayushi Chauhan, Francisco Vega, Christopher R. Flowers, Jason R. Westin
Journal: Blood
Blood (2024) 144 (Supplement 1): 4454.
https://doi.org/10.1182/blood-2024-211247
Published: 2024
Journal Articles

Outcomes in Early Relapse of Follicular Lymphoma Versus Early Histologic Transformation Following Firstline Immunochemotherapy in Follicular Lymphoma

Free
Carla Casulo, Melissa C. Larson, Jonathan R Day, Urshila Durani, Mazie Tsang, Jonathan W. Friedberg, Grzegorz S. Nowakowski, Jean L. Koff, Dai Chihara, Richard Burack, Thomas M. Habermann, Loretta Nastoupil, Izidore S. Lossos, Peter Martin, Matthew Holets, Brad S. Kahl, Jonathan J. Cohen, James R. Cerhan, Christopher R. Flowers, Brian K. Link, Matthew J. Maurer
Journal: Blood
Blood (2024) 144 (Supplement 1): 1652.
https://doi.org/10.1182/blood-2024-201078
Published: 2024
Journal Articles

Use of Molecular Immune Signatures for Frontline Treatment Selection in Patients with Advanced Stage Follicular Lymphoma

Free
Tony Z. Zhuang, Lei Feng, Dai Chihara, Chijioke Nze, Amy A. Ayers, Mansoor Noorani, James D. Ayres, Daniela E. Duenas, Kumudha Balakrishnan, Ekaterina Nesterenko, Mark Meerson, Ksenia Zornikova, Krystle Nomie, Nikita Kotlov, Nathan Fowler, Maria Alma Rodriguez, Sattva S. Neelapu, Christopher R. Flowers, Paolo Strati
Journal: Blood
Blood (2024) 144 (Supplement 1): 2982.
https://doi.org/10.1182/blood-2024-202654
Published: 2024
Journal Articles

Subsets of Follicular Lymphoma (FL) 3B Have Divergent Biological Behavior and Clinical Outcome: Results from the Prospective Multicenter MER and LEO Cohorts

Free
Patrizia Mondello, Brianna J Negaard, Andrew L. Feldman, Brian K. Link, Carla Casulo, Dai Chihara, David A Russler-Germain, Jason Romancik, Caitlin Gribbin, Sara Haddadi, Eric Mou, Ivana N. Micallef, Patrick B. Johnston, Anne J. Novak, Yucai Wang, Rebecca L. King, Thomas M. Habermann, Peter Martin, Grzegorz S. Nowakowski, Loretta Nastoupil, James R. Cerhan, Christopher R. Flowers, Izidore S. Lossos, Richard Burack, Matthew J. Maurer, Stephen M. Ansell
Journal: Blood
Blood (2024) 144 (Supplement 1): 1629.
https://doi.org/10.1182/blood-2024-194681
Published: 2024
Journal Articles

Efficacy and Safety Outcomes of CAR T-Cell Therapies in Patients with Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma Who Received Prior Treatment with Mosunetuzumab

Free
Adam Braun, Stephen J. Schuster, Loretta Nastoupil, Nancy L. Bartlett, Mazyar Shadman, Anita Kumar, Dimitrios Tzachanis, Dai Chihara, Mei Wu, Michael C. Wei, Shen Yin, Jing Qi Hao, Qian Zhu, Yong Mun, L. Elizabeth Budde
Journal: Blood
Blood (2024) 144 (Supplement 1): 6555.
https://doi.org/10.1182/blood-2024-198409
Published: 2024
Journal Articles

Evaluating the Clinical Utility of Real-Time Comprehensive Whole Exome Sequencing and RNA-Seq for Patients with Diffuse Large B-Cell Lymphoma

Free
Dai Chihara, Kumudha Balakrishnan, Gita Masand, Robert Andrew Harkins, Neha Akkad, Anna Novokreshchenova, Alexander Bagaev, Nikita Kotlov, Ekaterina Postovalova, Eduardo Shugaev-Mendosa, Yuliya Gracheva, Kelley Lauziere, Leznath Kaneunyenye, Brianna McKenna, Amber Berlinski, McKenna Walsh, Linnea Larson, Mariam Kotsinyan, Anna Samokhina, Sheila T Yong, Krystle Nomie, Nathan H. Fowler, Christopher R. Flowers, Jason R. Westin
Journal: Blood
Blood (2024) 144 (Supplement 1): 4364.
https://doi.org/10.1182/blood-2024-209105
Published: 2024
Journal Articles

Impact of Pre-Existing Mental Health Disorders (MHD) on CAR T-Cell Therapy Outcomes in Patients with Large B-Cell Lymphoma

Free
Sushanth Gouni, Anath Lionel, Lei Feng, Charles Gaulin, Tejaswini Reddy, Amrit S. Gonugunta, Victoria Chu, Taylor Hopper, Amy A. Ayers, Inimfon Jackson, Ajlan Al Zaki, Michelle A.T. Hildebrandt, Loretta Nastoupil, Dai Chihara, Chijioke Nze, Jeremy Ramdial, Elizabeth J. Shpall, Jason R. Westin, Christopher R. Flowers, Paolo Strati, Sattva S. Neelapu, Rachel Lynn, Sairah Ahmed
Journal: Blood
Blood (2024) 144 (Supplement 1): 4508.
https://doi.org/10.1182/blood-2024-198053
Published: 2024
Journal Articles

Utility of PET/CT Imaging in Predicting Outcomes of Patients with Lymphoid Malignancy-Associated Hemophagocytic Lymphohistiocytosis: A Retrospective Analysis from a Single Tertiary Center

Free
Rishab Prakash, James Long, Benjamin Mescher, Paul Edelkamp, Jr., Mark Knafl, Jeff Jin, Trey Kell, Naveen Garg, Ajlan Al Zaki, Dai Chihara, Luis Malpica, Ranjit Nair, Swaminathan P Iyer
Journal: Blood
Blood (2024) 144 (Supplement 1): 5127.
https://doi.org/10.1182/blood-2024-211892
Published: 2024
Journal Articles

Identifying the Barriers of Clinical Trial Access after CAR T-Cell Therapy in Relapsed/Refractory Large B-Cell Lymphoma

Free
Kunhwa Kim, Amy Ayers, Sairah Ahmed, Linda Claret, Paolo Strati, Ranjit Nair, Chijioke Nze, Jeremy Ramdial, Janet Torres, Elizabeth J. Shpall, Luis E. Fayad, Loretta Nastoupil, Jason R. Westin, Christopher R. Flowers, Sattva S. Neelapu, Dai Chihara
Journal: Blood
Blood (2024) 144 (Supplement 1): 5121.
https://doi.org/10.1182/blood-2024-211023
Published: 2024
Journal Articles

Collective Analysis of Genomic Data Sets to Assess the Impact of Eligibility Criteria on Molecular Subsets in First-Line Clinical Trials for Patients with Diffuse Large B-Cell Lymphoma

Free
Robert Andrew Harkins, Dai Chihara, Christopher R. Flowers
Journal: Blood
Blood (2024) 144 (Supplement 1): 2970.
https://doi.org/10.1182/blood-2024-198813
Published: 2024
Journal Articles

Occurrence and Predictors of Patient Reported Fertility Discussions in Non-Hodgkin Lymphoma Patients: Utilizing the Lymphoma Epidemiology of Outcomes (LEO) Cohort Study

Free
Nadia Toumeh, Melissa C. Larson, Bri J Negaard, Carla Casulo, Sairah Ahmed, Matthew J. Maurer, Andrew L. Feldman, Brian K. Link, Jonathon B. Cohen, Thomas M. Habermann, Dai Chihara, Izidore S. Lossos, Jonathan W. Friedberg, Brad Kahl, Peter Martin, Christopher R. Flowers, James R. Cerhan, Annalynn M Williams, Allison C. Rosenthal, Carrie A Thompson, Urshila Durani
Journal: Blood
Blood (2024) 144 (Supplement 1): 3736.
https://doi.org/10.1182/blood-2024-211091
Published: 2024
Journal Articles

Outcomes of Relapsed or Refractory Diffuse Large B-Cell Lymphoma Treated with R-GemOx: A Multi-Center Retrospective Cohort Study

Free
Samuel Yamshon, Jean L. Koff, Melissa C. Larson, Brad S. Kahl, Carla Casulo, Izidore S. Lossos, Sara Haddadi, Michele D. Stanchina, Dai Chihara, Amy A. Ayers, Thomas M. Habermann, Yucai Wang, Arushi Khurana, Grzegorz S. Nowakowski, Tanner W Reicks, Umar Farooq, Brian K. Link, Jonathon B. Cohen, Peter Martin, Jia Li, Ashwini Shewade, Connie Lee Batlevi, Andrea Lo-Rossi, David Fox, Anthony Masaquel, Yong Mun, James R. Cerhan, Christopher R. Flowers, Matthew J. Maurer, Loretta Nastoupil
Journal: Blood
Blood (2024) 144 (Supplement 1): 3093.
https://doi.org/10.1182/blood-2024-208111
Published: 2024
Journal Articles

Clinical Trial Success Rate in Lymphoma: Fate of Trials and Agents from 2000 to 2023

Free
Zhiping Luo, Meng Li, Christopher R. Flowers, Dai Chihara
Journal: Blood
Blood (2024) 144 (Supplement 1): 7597.
https://doi.org/10.1182/blood-2024-208810
Published: 2024
Journal Articles

T-Cell Lymphoma Associated Hemophagocytic Lymphohistiocytosis Has Worse Survival When Compared to T-Cell Lymphoma: A Retrospective Analysis from a Single Tertiary Center

Free
Amrit S. Gonugunta, Rishab Prakash, Ranjit Nair, Ajlan Al Zaki, Sairah Ahmed, Chijioke Nze, Dai Chihara, Frederick Hagemeister, Hun Ju Lee, Jason R. Westin, Krina K. Patel, Luis E. Fayad, Luis Malpica, Maria Alma Rodriguez, Michael Wang, Preetesh Jain, Paolo Strati, Sattva S. Neelapu, Christopher R. Flowers, Swaminathan P Iyer
Journal: Blood
Blood (2024) 144 (Supplement 1): 6420.
https://doi.org/10.1182/blood-2024-211482
Published: 2024
Journal Articles

Phase II Trial of Axicabagene Ciloleucel and Glofitamab As Second-Line Therapy for Patients with Relapsed or Refractory Large B-Cell Lymphoma

Free
Kunhwa Kim, Dai Chihara, Luis E. Fayad, Sattva S. Neelapu, Sairah Ahmed, Frederick Hagemeister, Chijioke Nze, Swaminathan P Iyer, Preetesh Jain, Michael Wang, Paolo Strati, Fateeha Furqan, Ayushi Chauhan, Michael R. Green, Christopher R. Flowers, Jason R. Westin
Journal: Blood
Blood (2024) 144 (Supplement 1): 4511.1.
https://doi.org/10.1182/blood-2024-205196
Published: 2024
Journal Articles

CTEP 10590, NORM: Nodular Lymphocyte Predominant Hodgkin Lymphoma Patients Treated in a Randomized Phase II Trial with Either Rituximab or Mosunetuzumab

Free
Raphael Steiner, Allison M. Bock, Alex F. Herrera, Omer Zulfa, Marc Hoffmann, Sami Ibrahimi, Natalie Galanina, Hun Ju Lee, Michael Green, Ruitao Lin, Chelsea C. Pinnix, Alison Moskowitz, Joachim Yahalom, Dai Chihara
Journal: Blood
Blood (2024) 144 (Supplement 1): 4434.2.
https://doi.org/10.1182/blood-2024-202516
Published: 2024