Skip to Main Content

Advertisement intended for health care professionals

Close

ASH
ASH Clinical News
ASH Image Bank Open External Link
ASH News Daily
ASH-SAP
Blood Journals
Hematology
The Hematologist
International

header search

search input Search input auto suggest

filter your search

Search

Menu

Issues
- Current Issue
- All Issues
First edition
Abstracts
Collections
Author Center
About

Skip Nav Destination

Issue Archive

Select Decade

Select Year

Issue

Volume 117, Issue 17

April 28 2011

Blood Cover Image for Volume 117, Issue 17

In this Issue

Inside Blood
Plenary Paper
Perspectives
Review Article
Clinical Trials and Observations
Hematopoiesis and Stem Cells
Immunobiology
Lymphoid Neoplasia
Myeloid Neoplasia
Phagocytes, Granulocytes, and Myelopoiesis
Platelets and Thrombopoiesis
Red Cells, Iron, and Erythropoiesis
Thrombosis and Hemostasis
Transfusion Medicine
Transplantation
Vascular Biology
Other Departments

Table of Contents

Inside Blood

INSIDE BLOOD

DARTs take aim at BiTEs

Christoph Rader

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

CLINICAL TRIALS

The metabolic cost of childhood ALL

Paul C. Nathan,Stacey L. Urbach

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

PLATELETS & THROMBOPOIESIS

Oxidative stress may cause ITP

Paul Imbach

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

THROMBOSIS & HEMOSTASIS

To gel or not to gel

Dennis K. Galanakis

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

Plenary Paper

PLENARY PAPER

Lenalidomide targets clonogenic side population in multiple myeloma: pathophysiologic and clinical implications

Jana Jakubikova,Sophia Adamia,Maria Kost-Alimova,Steffen Klippel,David Cervi,John F. Daley,Dana Cholujova,Sun-Young Kong,Merav Leiba,Simona Blotta,Melissa Ooi,Jake Delmore,Jacob Laubach,Paul G. Richardson,Jan Sedlak,Kenneth C. Anderson,Constantine S. Mitsiades

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

Supplemental data

Perspectives

Is normal hematopoiesis maintained solely by long-term multipotent stem cells?

Marina Cavazzana-Calvo,Alain Fischer,Frederic D. Bushman,Emmanuel Payen,Salima Hacein-Bey-Abina,Philippe Leboulch

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

Review Article

Hepcidin and iron regulation, 10 years later

Tomas Ganz

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

Clinical Trials and Observations

A randomized controlled study in patients with newly diagnosed severe aplastic anemia receiving antithymocyte globulin (ATG), cyclosporine, with or without G-CSF: a study of the SAA Working Party of the European Group for Blood and Marrow Transplantation
CME

André Tichelli,Hubert Schrezenmeier,Gérard Socié,Judith Marsh,Andrea Bacigalupo,Ulrich Dührsen,Anke Franzke,Michael Hallek,Eckhard Thiel,Martin Wilhelm,Britta Höchsmann,Alain Barrois,Kim Champion,Jakob R. Passweg

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

Supplemental data

Prevalence and risk factors of the metabolic syndrome in adult survivors of childhood leukemia
Clinical Trials & Observations

Claire Oudin,Marie-Claude Simeoni,Nicolas Sirvent,Audrey Contet,Audrey Begu-Le Coroller,Pierre Bordigoni,Catherine Curtillet,Maryline Poirée,Isabelle Thuret,Barbara Play,Mara Carazza Massot,Pascal Chastagner,Hervé Chambost,Pascal Auquier,Gérard Michel

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

Integrative prognostic risk score in acute myeloid leukemia with normal karyotype
Clinical Trials & Observations

Frederik Damm,Michael Heuser,Michael Morgan,Katharina Wagner,Kerstin Görlich,Anika Großhennig,Iyas Hamwi,Felicitas Thol,Ewa Surdziel,Walter Fiedler,Michael Lübbert,Lothar Kanz,Christoph Reuter,Gerhard Heil,Ruud Delwel,Bob Löwenberg,Peter J. M. Valk,Jürgen Krauter,Arnold Ganser

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

Supplemental data

Hematopoiesis and Stem Cells

Jagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions

Inge Van de Walle,Greet De Smet,Martina Gärtner,Magda De Smedt,Els Waegemans,Bart Vandekerckhove,Georges Leclercq,Jean Plum,Jon C. Aster,Irwin D. Bernstein,Cynthia J. Guidos,Bruno Kyewski,Tom Taghon

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

Supplemental data

The replication rate of human hematopoietic stem cells in vivo

Sandra N. Catlin,Lambert Busque,Rosemary E. Gale,Peter Guttorp,Janis L. Abkowitz

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

Supplemental data

Immunobiology

CX3CR1 expression defines 2 KLRG1⁺ mouse NK-cell subsets with distinct functional properties and positioning in the bone marrow

Giuseppe Sciumè,Giulia De Angelis,Giorgia Benigni,Andrea Ponzetta,Stefania Morrone,Angela Santoni,Giovanni Bernardini

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

Supplemental data

Silencing of c-Fos expression by microRNA-155 is critical for dendritic cell maturation and function

Isabelle Dunand-Sauthier,Marie-Laure Santiago-Raber,Leonardo Capponi,Charles E. Vejnar,Olivier Schaad,Magali Irla,Queralt Seguín-Estévez,Patrick Descombes,Evgeny M. Zdobnov,Hans Acha-Orbea,Walter Reith

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

Supplemental data

Monocytes control natural killer cell differentiation to effector phenotypes

Katrina Soderquest,Nick Powell,Carmelo Luci,Nico van Rooijen,Andrés Hidalgo,Frederic Geissmann,Thierry Walzer,Graham M. Lord,Alfonso Martín-Fontecha

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

Supplemental data

Lymphoid Neoplasia

Novel type II anti-CD20 monoclonal antibody (GA101) evokes homotypic adhesion and actin-dependent, lysosome-mediated cell death in B-cell malignancies

Waleed Alduaij,Andrei Ivanov,Jamie Honeychurch,Eleanor J. Cheadle,Sandeep Potluri,Sean H. Lim,Kazuyuki Shimada,Claude H. T. Chan,Alison Tutt,Stephen A. Beers,Martin J. Glennie,Mark S. Cragg,Tim M. Illidge

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

Supplemental data

Combination anti-CD74 (milatuzumab) and anti-CD20 (rituximab) monoclonal antibody therapy has in vitro and in vivo activity in mantle cell lymphoma

Lapo Alinari,Bo Yu,Beth A. Christian,Fengting Yan,Jungook Shin,Rosa Lapalombella,Erin Hertlein,Mark E. Lustberg,Carl Quinion,Xiaoli Zhang,Gerard Lozanski,Natarajan Muthusamy,Mette Prætorius-Ibba,Owen A. O'Connor,David M. Goldenberg,John C. Byrd,Kristie A. Blum,Robert A. Baiocchi

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

Supplemental data

Application of dual affinity retargeting molecules to achieve optimal redirected T-cell killing of B-cell lymphoma

Paul A. Moore,Wenjun Zhang,G. Jonah Rainey,Steve Burke,Hua Li,Ling Huang,Sergey Gorlatov,Maria Concetta Veri,Sudeepta Aggarwal,Yinhua Yang,Kalpana Shah,Linda Jin,Sunan Zhang,Leilei He,Tengfei Zhang,Valentina Ciccarone,Scott Koenig,Ezio Bonvini,Syd Johnson

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

Supplemental data

Myeloid Neoplasia

Coexpression of Tim-3 and PD-1 identifies a CD8⁺ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia

Qing Zhou,Meghan E. Munger,Rachelle G. Veenstra,Brenda J. Weigel,Mitsuomi Hirashima,David H. Munn,William J. Murphy,Miyuki Azuma,Ana C. Anderson,Vijay K. Kuchroo,Bruce R. Blazar

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

Supplemental data

Prognostic impact of SNP array karyotyping in myelodysplastic syndromes and related myeloid malignancies

Ramon V. Tiu,Lukasz P. Gondek,Christine L. O'Keefe,Paul Elson,Jungwon Huh,Azim Mohamedali,Austin Kulasekararaj,Anjali S. Advani,Ronald Paquette,Alan F. List,Mikkael A. Sekeres,Michael A. McDevitt,Ghulam J. Mufti,Jaroslaw P. Maciejewski

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

Supplemental data

Phagocytes, Granulocytes, and Myelopoiesis

Matrix metalloproteinase 12 overexpression in myeloid lineage cells plays a key role in modulating myelopoiesis, immune suppression, and lung tumorigenesis

Peng Qu,Cong Yan,Hong Du

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

Supplemental data

Platelets and Thrombopoiesis

The role of vanin-1 and oxidative stress–related pathways in distinguishing acute and chronic pediatric ITP
Clinical Trials & Observations

Bing Zhang,Clara Lo,Lei Shen,Ruchira Sood,Carol Jones,Kristina Cusmano-Ozog,Shaun Park-Snyder,Wendy Wong,Michael Jeng,Tina Cowan,Edgar G. Engleman,James L. Zehnder

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

Supplemental data

Down-regulation of stathmin expression is required for megakaryocyte maturation and platelet production

Camelia Iancu-Rubin,David Gajzer,Joseph Tripodi,Vesna Najfeld,Ronald E. Gordon,Ronald Hoffman,George F. Atweh

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

Supplemental data

Red Cells, Iron, and Erythropoiesis

Tmprss6 is a genetic modifier of the Hfe-hemochromatosis phenotype in mice

Karin E. Finberg,Rebecca L. Whittlesey,Nancy C. Andrews

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

Supplemental data

A transient definitive erythroid lineage with unique regulation of the β-globin locus in the mammalian embryo

Kathleen E. McGrath,Jenna M. Frame,George J. Fromm,Anne D. Koniski,Paul D. Kingsley,Jane Little,Michael Bulger,James Palis

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

Supplemental data

Thrombosis and Hemostasis

Visualization and identification of the structures formed during early stages of fibrin polymerization

Irina N. Chernysh,Chandrasekaran Nagaswami,John W. Weisel

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

Supplemental data

Evaluation of the profibrinolytic properties of an anti-TAFI monoclonal antibody in a mouse thromboembolism model

Ellen Vercauteren,Jan Emmerechts,Miet Peeters,Marc F. Hoylaerts,Paul J. Declerck,Ann Gils

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

Supplemental data

A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13

Minyun Zhou,Xianchi Dong,Carsten Baldauf,Hua Chen,Yanfeng Zhou,Timothy A. Springer,Xinping Luo,Chen Zhong,Frauke Gräter,Jianping Ding

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

Supplemental data

Transfusion Medicine

Chromatin-modifying agents promote the ex vivo production of functional human erythroid progenitor cells

Pratima Chaurasia,Dmitriy Berenzon,Ronald Hoffman

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

Supplemental data

Transplantation

Radioimmunotherapy-based conditioning for hematopoietic cell transplantation in children with malignant and nonmalignant diseases
Clinical Trials & Observations

Ansgar S. Schulz,Gerhard Glatting,Manfred Hoenig,Catharina Schuetz,Susanne A. Gatz,Simon Grewendorf,Monika Sparber-Sauer,Rainer Muche,Norbert Blumstein,Gabriele Kropshofer,Meinolf Suttorp,Donald Bunjes,Klaus-Michael Debatin,Sven N. Reske,Wilhelm Friedrich

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

Supplemental data

Patient-reported quality of life is associated with severity of chronic graft-versus-host disease as measured by NIH criteria: report on baseline data from the Chronic GVHD Consortium
Clinical Trials & Observations

Joseph Pidala,Brenda Kurland,Xiaoyu Chai,Navneet Majhail,Daniel J. Weisdorf,Steven Pavletic,Corey Cutler,David Jacobsohn,Jeanne Palmer,Sally Arai,Madan Jagasia,Stephanie J. Lee

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

Supplemental data

Vascular Biology

Priming of the vascular endothelial growth factor signaling pathway by thrombospondin-1, CD36, and spleen tyrosine kinase

Shideh Kazerounian,Mark Duquette,Millys A. Reyes,James T. Lawler,Keli Song,Carole Perruzzi,Luca Primo,Roya Khosravi-Far,Federico Bussolino,Isaac Rabinovitz,Jack Lawler

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

Supplemental data

An important role of lymphatic vessel activation in limiting acute inflammation

Reto Huggenberger,Shoib S. Siddiqui,Daniela Brander,Stefan Ullmann,Kathrin Zimmermann,Maria Antsiferova,Sabine Werner,Kari Alitalo,Michael Detmar

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

Supplemental data

Other Departments

Continuing Medical Education (CME) questions: ATG and cyclosporine with or without G-CSF in SAA
CME

View Articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text

Cover Image

Cover Image

CD20 and CD74 labeling by specific fluorescent antibodies. Binding of CD20 and CD74 in mantle cell lymphoma cells was examined by laser-scanning confocal microscopy. Cells were incubated with rhodamine-conjugated rituximab (red) and Alexa Fluor 488-conjugated milatuzumab (green) in the presence of a cross-linking antibody, for 2 hours at 37°C. DRAQ5 was used for nuclear staining (blue). Cross-linked milatuzumab forms large aggregates and colocalizes with cross-linked rituximab on the surface of mantle cell lymphoma cells. See the article by Alinari et al on page 4530.
Front Matter
Table of Contents
Back Matter
Advertising
Editorial Board

Advertisement intended for health care professionals

Email alerts

First Edition Alert

Latest Issue Alert

Latest
Most Read
Most Cited

Disrupting tRNA modifications to target mitochondrial vulnerabilities in drug-resistant leukemia cells

Metabolic Adaptation of Regenerative Hematopoiesis Depends on Docking-Independent Mitochondrial Connexin-43

Pretransplant targeting of TNFRSF25 and CD25 stimulates recipient Tregs in target tissues, ameliorating GVHD post-HSCT

Preclinical advances in glofitamab combinations: a new frontier for non-Hodgkin lymphoma

Sequential Targeting in Multiple Myeloma: Talquetamab, a GPRC5D bispecific antibody, as a Bridge to BCMA CAR-T cell therapy

Advertisement intended for health care professionals

Advertisement intended for health care professionals

About Blood
Abstracts
Advertising in Blood

Alerts
All Issues
Author Guide

Blood Classifieds
Collections
Contact Us

Current Issue
First edition
Newsroom

Permissions
Subscriptions
Submit to Blood

American Society of Hematology
2021 L Street NW, Suite 900
Washington, DC 20036
TEL +1 202-776-0544
FAX +1 202-776-0545

ASH Publications

Blood
Blood Advances
Blood Global Hematology
Blood Immunology & Cellular Therapy
Blood Neoplasia
Blood Red Cells & Iron
Blood Vessels, Thrombosis & Hemostasis
Hematology, ASH Education Program
ASH Clinical News
ASH-SAP
The Hematologist

American Society of Hematology

ASH Home
ASH Image Bank
ASH Store

Advocacy
Education
Meetings
Research

Copyright 2025 by American Society of Hematology

Cookie Settings
Privacy Policy
Cookie Policy
Terms of Use
Contact Us

This Feature Is Available To Subscribers Only

Sign In or Create an Account

Advertisement intended for health care professionals