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Journal Articles

PRMT5 is a therapeutic vulnerability in cutaneous T-cell lymphoma

Nicole Peterman, Pushpa Lata, Christoph Weigel, Sydney Leon, Ian Hout, Wing Chan, Ronny Schmidt, Ha Tran, Youssef Youssef, Peggy Scherle, Neha Bhagwat, John Reneau, Catherine Chung, Jonathan Brammer, Ryan Wilcox, Lapo Alinari, Robert Baiocchi, Walter Hanel

Blood (2025) 146 (Supplement 1): 1529.

https://doi.org/10.1182/blood-2025-1529

Published: 2025

Journal Articles

Safety and efficacy of transposon, BAFF-ligand directed chimeric antigen receptor T cells (LMY-920) with pre-apheresis obinutuzumab for patients with Relapsed/Refractory chronic lymphocytic leukemia and small lymphocytic lymphoma

Paolo Caimi, Leland Metheny, Lapo Alinari, Changchun Deng, Matthew Spear, Jeff Liter, Branden Moriarity, Beau Webber, Jennifer Woyach, Brian Hill, J. Joseph Melenhorst

Blood (2025) 146 (Supplement 1): 4177.

https://doi.org/10.1182/blood-2025-4177

Published: 2025

Journal Articles

Phase ib study to assess the efficacy and safety of epcoritamab in relapsed or refractory post-transplant lymphoproliferative disorder

Timothy Voorhees, Rina Welkie, Hemalatha Rao, Yazeed Sawalha, David Bond, Audrey Sigmund, Yun Choi, John Reneau, Walter Hanel, Polina Shindiapina, Jonathan Brammer, Beth Christian, Lapo Alinari, Nancy Bartlett, Kami Maddocks, Robert Baiocchi

Blood (2025) 146 (Supplement 1): 8240.

https://doi.org/10.1182/blood-2025-8240

Published: 2025

Journal Articles

Phase IB/II trial of epcoritamab plus ibrutinib in patients with relapsed/refractory aggressive B-cell non-Hodgkin lymphoma

Yazeed Sawalha, Marie Hu, Rina Welkie, Aubree Shoemaker, Yun Choi, Audrey Sigmund, Timothy Voorhees, David Bond, John Reneau, Lapo Alinari, Jonathan Brammer, Beth Christian, Robert Baiocchi, Veronika Bachanova, Kami Maddocks

Blood (2025) 146 (Supplement 1): 8239.

https://doi.org/10.1182/blood-2025-8239

Published: 2025

Journal Articles

Trials in progress - A phase II study of pemigatinib in patients with relapsed or refractory B-cell non-Hodgkin lymphomas (PERFORM)

Narendranath Epperla, Yizhe Xu, Allison Bock, Kelsey Baron, Lindsey Fitzgerald, Harsh Shah, Daniel Ermann, Lalit Sehgal, Lapo Alinari, Boyu Hu

Blood (2025) 146 (Supplement 1): 8235.

https://doi.org/10.1182/blood-2025-8235

Published: 2025

Journal Articles

Selective targeting of sumoylation disrupts mitochondrial homeostasis via TRAP1 to suppress growth of non-Hodgkin lymphoma (NHL) B-cells

Vi Lam, Tingting Liu, Haifeng Shen, Olga Danilova, Katarzyna Dabrowska, Sonia Rodriguez-Rodriguez, Courtney Jones, Martina Cusan, Angelo D'Alessandro, Lapo Alinari, Lili Wang, Tycel Phillips, Patrick Pirrotte, Zheng Xia, Alexey Danilov

Blood (2025) 146 (Supplement 1): 5087.

https://doi.org/10.1182/blood-2025-5087

Published: 2025

Journal Articles

Safety and immunomodulatory effects of siltuximab prophylaxis prior to standard of care CD19 directed chimeric antigen receptor T-cell (CD19.CART) therapy for B-cell lymphomas: Final phase I trial results

Blood (2025) 146 (Supplement 1): 2385.

https://doi.org/10.1182/blood-2025-2385

Published: 2025

Journal Articles

Anti-CD19 chimeric antigen receptor T-cell therapy for patients with non-Hodgkin's lymphoma and concurrent autoimmune disease

Blood (2025) 146 (Supplement 1): 1935.

https://doi.org/10.1182/blood-2025-1935

Published: 2025

Journal Articles

Tumor Microenvironment-Induced Interleukin-6 Regulates Proliferation and Survival in Patients with Mantle Cell Lymphoma (MCL) By Activating FGFR1 Signaling

Yuangfeng Wang, Satishkumar Singh, Audrey Odier, Alessandro La Ferlita, Wing Chan, Maxine Berger, Sriya Sreekanth, Narendranath Epperla, Natarajan Muthusamy, Robert Baiocchi, Lapo Alinari, Mamta Gupta, Lalit Sehgal

Blood (2024) 144 (Supplement 1): 4371.

https://doi.org/10.1182/blood-2024-209186

Published: 2024

Journal Articles

Steroid Prophylaxis in Patients Receiving CAR T-Cell Therapy for Relapsed and Refractory Non-Hodgkin Lymphoma

Blood (2024) 144 (Supplement 1): 4507.

https://doi.org/10.1182/blood-2024-206559

Published: 2024

Journal Articles

Transcriptomic Analysis in Mantle Cell Lymphoma Patients Identified MALAT1 Long-Non-Coding RNA to Regulate Cell Cycle Progression By Modulating EZH2/p57/Sox11 Axis

Satishkumar Singh, Alessandro La Ferlita, Neeraj Jain, Maxine Berger, Sriya Sreekanth, Rosario Distefano, Mamta Gupta, Natarajan Muthusamy, Robert Baiocchi, Lapo Alinari, Narendranath Epperla, Lalit Sehgal

Blood (2024) 144 (Supplement 1): 4350.

https://doi.org/10.1182/blood-2024-209941

Published: 2024

Journal Articles

Nivolumab in Combination with Dose Adjusted (DA) R-EPOCH for First-Line Treatment of Large B-Cell Lymphoma: Results from a Phase II Trial

David A. Bond, Ying Huang, John C. Reneau, Yazeed Sawalha, Jonathan E. Brammer, Timothy Voorhees, Narendranath Epperla, Audrey M. Sigmund, Lapo Alinari, Walter Hanel, Anna Gilmore, Misty Fleming, Kathleen Stamper, Robert Baiocchi, Beth Christian, Kami J. Maddocks

Blood (2024) 144 (Supplement 1): 1719.

https://doi.org/10.1182/blood-2024-194545

Published: 2024

Journal Articles

Targeting PRMT5-Mediated DNA Repair Pathway in Extra-Nodal NK/T-Cell Lymphoma (ENKTL)

Youssef Youssef, Walter Hanel, Wing Chan, Fiona C. Brown, Claire Hinterschied, Jobeth Helmig-Mason, Neha Bhagwat, Kris Vaddi, Peggy A Scherle, Amin Noorani, Sr., Aharon G. Freud, Lapo Alinari, Christopher C. Oakes, Bethany L. Mundy-Bosse, Robert Baiocchi

Blood (2024) 144 (Supplement 1): 5848.

https://doi.org/10.1182/blood-2024-201980

Published: 2024

Journal Articles

Spatial Tissue Analysis of Secondary Sarcoma Following CAR T Cell Therapy for B Cell Lymphoma

Dina Schneider, Jia-Jye Lee, Jinling Wang, Robert Pinard, Peirong Hu, Kun Luo, Ngoc Tran, Yazeed Sawalha, Nathan Denlinger, Evandro Bezerra, Pradyot Dash, Ashley Angell Krull, Lynn O'Donnell, Lapo Alinari, Dan Jones, Marcos de Lima, Sumithira Vasu

Blood (2024) 144 (Supplement 1): 7139.

https://doi.org/10.1182/blood-2024-203633

Published: 2024

Journal Articles

Initial Results of a First-in-Human, Phase I Study Point-of-Care Manufacturing of Trispecific CAR-T Cells Targeting CD19/20/22 in B-Cell Malignancies

Blood (2024) 144 (Supplement 1): 2078.

https://doi.org/10.1182/blood-2024-207532

Published: 2024

Journal Articles

Patterns of Use and Outcomes of Novel Agents in Patients with Relapsed or Refractory Large B-Cell Lymphoma: A Single-Center Retrospective Analysis

Sonia Godbole, Rina Li Welkie, Audrey M. Sigmund, Timothy Voorhees, Walter Hanel, David A. Bond, John C. Reneau, Lapo Alinari, Jonathan E. Brammer, Beth Christian, Robert Baiocchi, Kami J. Maddocks, Yazeed Sawalha

Blood (2024) 144 (Supplement 1): 4460.

https://doi.org/10.1182/blood-2024-207738

Published: 2024

Journal Articles

Acute Kidney Injury Following Chimeric Antigen Receptor T-Cell Therapy Is Associated with Inferior Survival for Patients with Relapsed or Refractory Large B-Cell Lymphoma

Blood (2024) 144 (Supplement 1): 3747.

https://doi.org/10.1182/blood-2024-203798

Published: 2024

Journal Articles

Impact of Baseline Osseous Involvement on Outcomes in Patients with Lymphoplasmacytic Lymphoma (LPL)/Waldenstrom's Macroglobulinemia (WM)

John Sharp, Subodh Bhatta, Noah Takacs, Kathleen Tong, Youssef Youssef, David A. Bond, Yazeed Sawalha, Audrey M. Sigmund, Lalit Sehgal, Lapo Alinari, Robert Baiocchi, Kami J. Maddocks, Beth Christian, Timothy Voorhees, Narendranath Epperla

Blood (2024) 144 (Supplement 1): 3737.

https://doi.org/10.1182/blood-2024-194399

Published: 2024

Journal Articles

Transcriptome Analysis at Locus-Specific Resolution Identified Alteration in Human Endogenous Retroviruses, a Class of Transposable Elements in Mantle Cell Lymphoma

Alessandro La Ferlita, Nicholas Staudinger, Lara Bayraktar, Katherine Chiappinelli, Lapo Alinari, Robert Baiocchi, Lalit Sehgal, Mamta Gupta

Blood (2024) 144 (Supplement 1): 1611.

https://doi.org/10.1182/blood-2024-208604

Published: 2024

Journal Articles

Targeting the DNA Damage Response through TBL1X in Mantle Cell Lymphoma

Betsy A Pray, Ethan Baiocchi, Sydney Leon, Brian Barta, Shirsha Koirala, Wing Chan, Walter Hanel, Lalit Sehgal, Robert Baiocchi, Lapo Alinari

Blood (2024) 144 (Supplement 1): 1403.

https://doi.org/10.1182/blood-2024-207407

Published: 2024

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PRMT5 is a therapeutic vulnerability in cutaneous T-cell lymphoma

Safety and efficacy of transposon, BAFF-ligand directed chimeric antigen receptor T cells (LMY-920) with pre-apheresis obinutuzumab for patients with Relapsed/Refractory chronic lymphocytic leukemia and small lymphocytic lymphoma

Phase ib study to assess the efficacy and safety of epcoritamab in relapsed or refractory post-transplant lymphoproliferative disorder

Phase IB/II trial of epcoritamab plus ibrutinib in patients with relapsed/refractory aggressive B-cell non-Hodgkin lymphoma

Trials in progress - A phase II study of pemigatinib in patients with relapsed or refractory B-cell non-Hodgkin lymphomas (PERFORM)

Selective targeting of sumoylation disrupts mitochondrial homeostasis via TRAP1 to suppress growth of non-Hodgkin lymphoma (NHL) B-cells

Safety and immunomodulatory effects of siltuximab prophylaxis prior to standard of care CD19 directed chimeric antigen receptor T-cell (CD19.CART) therapy for B-cell lymphomas: Final phase I trial results

Anti-CD19 chimeric antigen receptor T-cell therapy for patients with non-Hodgkin's lymphoma and concurrent autoimmune disease

Tumor Microenvironment-Induced Interleukin-6 Regulates Proliferation and Survival in Patients with Mantle Cell Lymphoma (MCL) By Activating FGFR1 Signaling

Steroid Prophylaxis in Patients Receiving CAR T-Cell Therapy for Relapsed and Refractory Non-Hodgkin Lymphoma

Transcriptomic Analysis in Mantle Cell Lymphoma Patients Identified MALAT1 Long-Non-Coding RNA to Regulate Cell Cycle Progression By Modulating EZH2/p57/Sox11 Axis

Nivolumab in Combination with Dose Adjusted (DA) R-EPOCH for First-Line Treatment of Large B-Cell Lymphoma: Results from a Phase II Trial

Targeting PRMT5-Mediated DNA Repair Pathway in Extra-Nodal NK/T-Cell Lymphoma (ENKTL)

Spatial Tissue Analysis of Secondary Sarcoma Following CAR T Cell Therapy for B Cell Lymphoma

Initial Results of a First-in-Human, Phase I Study Point-of-Care Manufacturing of Trispecific CAR-T Cells Targeting CD19/20/22 in B-Cell Malignancies

Patterns of Use and Outcomes of Novel Agents in Patients with Relapsed or Refractory Large B-Cell Lymphoma: A Single-Center Retrospective Analysis

Acute Kidney Injury Following Chimeric Antigen Receptor T-Cell Therapy Is Associated with Inferior Survival for Patients with Relapsed or Refractory Large B-Cell Lymphoma

Impact of Baseline Osseous Involvement on Outcomes in Patients with Lymphoplasmacytic Lymphoma (LPL)/Waldenstrom's Macroglobulinemia (WM)

Transcriptome Analysis at Locus-Specific Resolution Identified Alteration in Human Endogenous Retroviruses, a Class of Transposable Elements in Mantle Cell Lymphoma

Targeting the DNA Damage Response through TBL1X in Mantle Cell Lymphoma

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American Society of Hematology

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