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Jinny Lee
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Journal Articles

Preliminary data from the Phase I/II study of nuvisertib, an oral investigational selective PIM1 inhibitor, in combination with momelotinib showed clinical responses in patients with relapsed/refractory myelofibrosis

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John Mascarenhas, Joseph Scandura, Vikas Gupta, Kazuya Shimoda, James McCloskey, Firas El Chaer, Prithviraj Bose, Raajit Rampal, Andrew Srisuwananukorn, Timothy Devos, Ruben Mesa, Professor Francesco Passamonti, Srinivas Tantravahi, David Ross, Lindsay Rein, Jean-Jacques Kiladjian, Takanori Teshima, Takuji Yamauchi, Noboru Asada, Anna Halpern, Tamanna Haque, Etienne Paubelle, Noriko Fukuhara, Pankit Vachhani, Michiko Ichii, Ronald Hoffman, Marcello Rotta, Michael Keng, Stefan Wickenhauser, Karen Ansaldo, Masataka Seki, Jinny Lee, Vincent Loksa, Zhonggai Li, Jason Foulks, Sujan Kabir, Jatin Shah, Claire Harrison
Journal: Blood
Blood (2025) 146 (Supplement 1): 482.
https://doi.org/10.1182/blood-2025-482
Published: 2025
Journal Articles

Nuvisertib, an oral investigational selective PIM1 kinase inhibitor, showed clinical responses strongly correlating with cytokine modulation in patients with relapsed/refractory myelofibrosis in the ongoing global phase I/II study

Free
Lindsay Rein, Firas El Chaer, Junichiro Yuda, Joseph Scandura, Shuichi Shirane, Kazuya Shimoda, Prithviraj Bose, Akiyoshi Takami, Alessandra Iurlo, Michiko Ichii, James McCloskey, Michael Keng, Samah Alimam, Noriko Fukuhara, Nikki Granacher, Giulia Benevolo, Alessandro Lucchesi, Tamanna Haque, Jean-Jacques Kiladjian, Srinivas Tantravahi, Pankit Vachhani, Anand Patel, Stanley Cheung, Paul Yeh, Francesca Palandri, Ashwin Kishtagari, Ciro Rinaldi, Marcello Rotta, Vincent Ribrag, Michael Loschi, Idoroenyi Amanam, Terrence Bradley, Karen Ansaldo, Masataka Seki, Guia Guffanti, Jinny Lee, Prasanthi Pellakuru, Zhonggai Li, Jason Foulks, Sujan Kabir, Jatin Shah, Raajit Rampal
Journal: Blood
Blood (2025) 146 (Supplement 1): 2018.
https://doi.org/10.1182/blood-2025-2018
Published: 2025
Journal Articles

Cytokine Modulation Correlates Strongly with Symptom Improvement in Patients with Myelofibrosis Treated with Nuvisertib (TP-3654), an Investigational Selective PIM1 Kinase Inhibitor

Free
Lindsay A.M. Rein, Firas El Chaer, Junichiro Yuda, Kazuya Shimoda, Raajit Rampal, Joseph M. Scandura, Akiyoshi Takami, James McCloskey, Michiko Ichii, Shuichi Shirane, Alessandra Iurlo, Prithviraj Bose, Alessandro Lucchesi, Giulia Benevolo, Idoroenyi Amanam, Pankit Vachhani, Srinivas K Tantravahi, Marcello Rotta, Yasushi Onishi, Jean-Jacques Kiladjian, Ciro Rinaldi, Nikki Granacher, Terrence Bradley, Anand Ashwin Patel, Michael Loschi, Samah Alimam, Stanley Cheung, Vincent Ribrag, Sujan Kabir, Masataka Seki, Karen Ansaldo, Guia Guffanti, Jinny Lee, Steven L. Warner, Jason M. Foulks, Ruben Mesa
Journal: Blood
Blood (2024) 144 (Supplement 1): 3179.
https://doi.org/10.1182/blood-2024-200999
Published: 2024