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James O. J. Davies
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Journal Articles

Enhancer heterogeneity in acute lymphoblastic leukemia drives differential gene expression in patients

Open Access
Alastair L. Smith, Nicholas Denny, Catherine Chahrour, Kim Sharp, Marta Arachi, Ana M. Dopico-Fernandez, Natalina Elliott, Joe R. Harman, Thomas Jackson, Huimin Geng, Owen Smith, Jonathan Bond, Irene Roberts, Ronald W. Stam, Nicholas T. Crump, James O. J. Davies, Anindita Roy, Thomas A. Milne
Journal: Blood
Blood (2025) 146 (17): 2073–2087.
https://doi.org/10.1182/blood.2024028019
Published: 2025
Includes: Supplemental data
Journal Articles

Focal deletions of a promoter tether activate the IRX3 oncogene in T-cell acute lymphoblastic leukemia

Available to Purchase
Sunniyat Rahman, Gianna Bloye, Nadine Farah, Jonas Demeulemeester, Joana R. Costa, David O’Connor, Rachael Pocock, Tanya Rapoz-D’Silva, Adam Turna, Lingyi Wang, SooWah Lee, Adele K. Fielding, Juliette Roels, Roman Jaksik, Małgorzata Dawidowska, Pieter Van Vlierberghe, Suzana Hadjur, Jim R. Hughes, James O. J. Davies, Alejandro Gutierrez, Michelle A. Kelliher, Peter Van Loo, Mark A. Dawson, Marc R. Mansour
Journal: Blood
Blood (2024) 144 (22): 2319–2326.
https://doi.org/10.1182/blood.2024024300
Published: 2024
Includes: Supplemental data
Journal Articles

A remarkable case of HbH disease illustrates the relative contributions of the α-globin enhancers to gene expression

Free
Mohsin Badat, James O. J. Davies, Christopher A. Fisher, Damien J. Downes, Anna Rose, Andreas B. Glenthøj, Eduard J. van Beers, Cornelis L. Harteveld, Douglas R. Higgs
Journal: Blood
Blood (2021) 137 (4): 572–575.
https://doi.org/10.1182/blood.2020006680
Published: 2021
Includes: Supplemental data
Journal Articles

Single-cell analysis of bone marrow–derived CD34 + cells from children with sickle cell disease and thalassemia

Free
Peng Hua, Noemi Roy, Josu de la Fuente, Guanlin Wang, Supat Thongjuea, Kevin Clark, Anindita Roy, Bethan Psaila, Neil Ashley, Yvonne Harrington, Claus Nerlov, Suzanne M. Watt, Irene Roberts, James O. J. Davies
Journal: Blood
Blood (2019) 134 (23): 2111–2115.
https://doi.org/10.1182/blood.2019002301
Published: 2019
Includes: Supplemental data