1-8 of 8
Jim R. Hughes
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Focal deletions of a promoter tether activate the IRX3 oncogene in T-cell acute lymphoblastic leukemia

Available to Purchase
Sunniyat Rahman, Gianna Bloye, Nadine Farah, Jonas Demeulemeester, Joana R. Costa, David O’Connor, Rachael Pocock, Tanya Rapoz-D’Silva, Adam Turna, Lingyi Wang, SooWah Lee, Adele K. Fielding, Juliette Roels, Roman Jaksik, Małgorzata Dawidowska, Pieter Van Vlierberghe, Suzana Hadjur, Jim R. Hughes, James O. J. Davies, Alejandro Gutierrez, Michelle A. Kelliher, Peter Van Loo, Mark A. Dawson, Marc R. Mansour
Journal: Blood
Blood (2024) 144 (22): 2319–2326.
https://doi.org/10.1182/blood.2024024300
Published: 2024
Includes: Supplemental data
Journal Articles

IRX3 Oncogene Activation in T-ALL through Enhancer Hijacking Caused By fto Intron 8 Deletions

Free
Sunniyat Rahman, Nadine Farah, Jonas Demeulemeester, Joana R Costa, Gianna Bloye, David O'Connor, Rachael Pocock, Adam Turna, SooWah Lee, Adele K. Fielding, Juliette Roels, Małgorzata Dawidowska, Pieter Van Vlierberghe, Suzana Hadjur, Alejandro Gutierrez, Michelle A Kelliher, Simone Riva, Jim R. Hughes, James O.J. Davies, Peter Van Loo, Mark A. Dawson, Marc R. Mansour
Journal: Blood
Blood (2022) 140 (Supplement 1): 1009–1010.
https://doi.org/10.1182/blood-2022-162930
Published: 2022
Journal Articles

Genotyping of Multiple Genomic Loci with Chromatin Accessibility Profiling in Single Cells Links Clonal Hierarchy with Epigenetic Variation in Acute Myeloid Leukemia

Free
Sven Turkalj, Niels Asger Jakobsen, Angus Groom, Marlen Metzner, Batchimeg Usukhbayar, Mirian Angulo Salazar, Kevin Clark, E. Ravza Gür, Lance D. Hentges, Paul Sopp, James O.J. Davies, Jim R. Hughes, Paresh Vyas
Journal: Blood
Blood (2022) 140 (Supplement 1): 1193–1194.
https://doi.org/10.1182/blood-2022-163139
Published: 2022
Journal Articles

Comparison of Fetal and Adult Erythroid Chromosomal Architectures Identifies a Novel Fetal Hemoglobin Regulatory Region

Free
Peng Huang, PhD, Cheryl A. Keller, PhD, Belinda Giardine, James O.J. Davies, Jim R. Hughes, Ross C Hardison, PhD, Gerd Blobel, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 774.
https://doi.org/10.1182/blood.V130.Suppl_1.774.774
Published: 2017
Journal Articles

Dynamics and Mechanics Of KLF1 Regulation In Erythropoiesis

Free
Kevin R. Gillinder, BSc PhD, Jim R. Hughes, Michael R. Tallack, BSc PhD, Graham Magor, BSc, Melissa Ilsley, BSc, James Davies, MD, Douglas Higgs, Andrew C. Perkins, MB BS PhD
Journal: Blood
Blood (2013) 122 (21): 2176.
https://doi.org/10.1182/blood.V122.21.2176.2176
Published: 2013
Journal Articles

Discovering Regulatory SNPs by Genome-Wide Analysis of Differential Scl/TAL-1 Occupancy in Human Primary Erythroid Cells,

Free
Marco De Gobbi, Jim R. Hughes, Karen M. Lower, Chris J. Derry, Emanuele Marchi, Jacqueline Sloane-Stanley, BSc, Nigel Roberts, BSc, Stephen Taylor, Catherine Porcher, Richard J. Gibbons, Douglas R. Higgs, DSc
Journal: Blood
Blood (2011) 118 (21): 3381.
https://doi.org/10.1182/blood.V118.21.3381.3381
Published: 2011
Journal Articles

Does Transcription of Remote α- Globin Regulatory Elements Affect Their Function?.

Free
Monika S Kowalczyk, MD, Jim R Hughes, DPhil, Jacqueline A Sharpe, PhD, Jill M Brown, BSc, Veronica J Buckle, PhD, William G Wood, PhD, Douglas R Higgs, FRS
Journal: Blood
Blood (2009) 114 (22): 4060.
https://doi.org/10.1182/blood.V114.22.4060.4060
Published: 2009
Journal Articles

Identification of a Gain-of-Function SNP Causing a New Model of α-Thalassaemia.

Free
Marco De Gobbi, MD, Vip Viprakasit, MD, PhD, Pieter J. de Jong, PhD, Yuko Yoshinaga, PhD, Jan-Fang Cheng, PhD, Jim R. Hughes, PhD, Chris A. Fisher, PhD, William G. Wood, PhD, Donald K. Bowden, PhD, Douglas R. Higgs, MD
Journal: Blood
Blood (2005) 106 (11): 523.
https://doi.org/10.1182/blood.V106.11.523.523
Published: 2005