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Francesco Buccisano
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Journal Articles

2025 Update on MRD in Acute Myeloid Leukemia: A Consensus Document from the ELN-DAVID MRD Working Party

Open Access
Jacqueline Cloos, Peter J.M. Valk, Christian Thiede, Konstanze Döhner, Gail J Roboz, Brent L. Wood, Roland B. Walter, Sa A Wang, Agnieszka Wierzbowska, Andrew H Wei, David Wu, Francois Vergez, Adriano Venditti, Bert A. van der Reijden, Arjan A van de Loosdrecht, Ing Soo Tiong, Felicitas R Thol, Marion Subklewe, Christophe Roumier, Tom Reuvekamp, Farhad Ravandi, Claude Preudhomme, Adriana Plesa, Jad Othman, Gert J. Ossenkoppele, Yishai Ofran, Aguirre Mimoun, Luca Maurillo, Agata Majchrzak, David C. de Leeuw, Wolfgang Kern, Dennis Dong Hwan Dong Hwan Kim, Maura Rosane Valério Ikoma-Colturato, Lukas H. Haaksma, Monica L Guzman, Michaela Feuring, Barbara Depreter, Anna Czyz, Veit L. Bücklein, Constance Baer, Costa Bachas, Sylvie D Freeman, Francesco Buccisano, Christopher S Hourigan, Richard James Dillon, Michael Heuser
Journal: Blood
Blood blood.2025031480.
https://doi.org/10.1182/blood.2025031480
Published: 2025
Includes: Supplemental data
Journal Articles

Establishing contemporary benchmarks for Acute Myeloid Leukemia outcomes and measurable residual disease: Real-world data utilization from the ELN-david MRD international working group

Free
Gail Roboz, Tom Reuvekamp, Jacqueline Cloos, Malte Von Bonin, Francesco Buccisano, Lukas Haaksma, Maura Ikoma-Colturato, Joana Brioso Infante, Dennis Kim, Chrysavgi Lalayanni, David de Leeuw, Josephine Anne Lucero, Francesco Mannelli, Luca Maurillo, Federico Moretti, Josep F Nomdedeu Guinot, Apostolia Papalexandri, Guillermo Ramil López, Maximilian Röhnert, Christoph Röllig, Anderson João Simione, Daniela Späth, Felicitas R Thol, Anne Tierens, Adriano Venditti, Francois Vergez, Michael Heuser, Konstanze Döhner
Journal: Blood
Blood (2025) 146 (Supplement 1): 5183.
https://doi.org/10.1182/blood-2025-5183
Published: 2025
Journal Articles

Mynerva-gimema AML1919 ameliorate Trial: EARLY intensification in FLT3-mutated ACUTE myeloid leukemia based on peripheral blast clearance

Free
Francesco Mannelli, Giacomo Gianfaldoni, Alfonso Piciocchi, Giovanni Marsili, Roberto Caporale, Ernesta Audisio, Antonino Mule', Alessandro Pulsoni, Antonio Curti, Crescenza Pasciolla, Patrizia Zappasodi, Chiara Cattaneo, Alessia Tieghi, Roberto Sartori, Luca Frison, Francesco Albano, Prassede Salutari, Sara Bencini, Benedetta Peruzzi, Matteo Piccini, Barbara Scappini, Francesca Crupi, Gaia Ciolli, Livia Gorreo Renzulli, Marco Chiarini, Francesco Buccisano, Adriano Venditti, Paola Fazi, Francesco Annunziato, Paola Guglielmelli, Alessandro Vannucchi
Journal: Blood
Blood (2025) 146 (Supplement 1): 5243.
https://doi.org/10.1182/blood-2025-5243
Published: 2025
Journal Articles

A pre-emptive bridge-to-transplant therapy for measurable residual disease with venetoclax and azacitidine in NPM1-mutated Acute Myeloid Leukemia: Updates from the ongoing GIMEMA AML2521 phase 2 trial

Free
Chiara Sartor, Anna Candoni, Alfonso Piciocchi, Giovanni Marsili, Paola Fazi, Cristina Papayannidis, Jacopo Nanni, Stefania Paolini, Luca Maurillo, Mario Tiribelli, Antonino Mule', Melissa Campanelli, Marianna Norata, Roberto Cairoli, Emanuela Ottaviani, Giulia Azteni, Maria Teresa Voso, Francesca Bonifazi, Enrico Maffini, Lorenzo Brunetti, Cristina Skert, Francesco Di Raimondo, Roberto Lemoli, Pellegrino Musto, Maria Paola Martelli, Brunangelo Falini, Adriano Venditti, Francesco Buccisano, Antonio Curti
Journal: Blood
Blood (2025) 146 (Supplement 1): 3516.
https://doi.org/10.1182/blood-2025-3516
Published: 2025
Journal Articles

Venetoclax and Azacitidine for Relapse Prevention in NPM1 -Mutated Acute Myeloid Leukemia in Molecular Failure: Results from the Ongoing Gimema AML2521 Phase 2 Trial

Free
Chiara Sartor, Anna Candoni, Alfonso Piciocchi, Giovanni Marsili, Paola Fazi, Cristina Papayannidis, Stefania Paolini, Gianluca Cristiano, Luca Maurillo, Mario Tiribelli, Antonino Mulè, Melissa Campanelli, Giovanni Marconi, Paola Minetto, Emanuela Ottaviani, Maria Teresa Voso, Francesca Bonifazi, Attilio Olivieri, Pellegrino Musto, Francesco Di Raimondo, Roberto Massimo Lemoli, Maria Paola Martelli, Brunangelo Falini, Michele Cavo, Adriano Venditti, Francesco Buccisano, Antonio Curti
Journal: Blood
Blood (2024) 144 (Supplement 1): 2893.
https://doi.org/10.1182/blood-2024-210315
Published: 2024
Journal Articles

Leukemic Phenotype Determines Prognostic Relevance of Limit of Quantification for Flow Cytometry-Based Measurable Residual Disease Assessment in Acute Myeloid Leukemia

Free
Lukas H. Haaksma, Raffaele Palmieri, Jesse M. Tettero, Tom Reuvekamp, Lok Lam Ngai, Costa Bachas, Angèle Kelder, Willemijn J. Scholten, Patrycja Gradowska, Valentina Arena, Anderson Simione, Luca Maurillo, Adriano Venditti, Bob Lowenberg, Gert J. Ossenkoppele, David C. de Leeuw, Maura R. V. Ikoma-Colturato, Francesco Buccisano, Jacqueline Cloos
Journal: Blood
Blood (2024) 144 (Supplement 1): 4329.
https://doi.org/10.1182/blood-2024-203158
Published: 2024
Journal Articles

Clinical Implications of Central Nervous System Involvement in Acute Myeloid Leukemia

Free
Giovangiacinto Paterno, Flavia Mallegni, Elisa Buzzatti, Maria Irno Consalvo, Elisa Meddi, Federico Moretti, Lucrezia De Marchi, Kristian Taka, Camilla Page, Massimiliano Marinoni, Luca Maurillo, Carmelo Gurnari, Raffaele Palmieri, Francesco Buccisano, Adriano Venditti, Maria Ilaria Del Principe
Journal: Blood
Blood (2024) 144 (Supplement 1): 4252.
https://doi.org/10.1182/blood-2024-209847
Published: 2024
Journal Articles

Real World Outcome of Unfit Patients with Acute Myeloid Leukemia Treated with the Combination Venetoclax Plus Hypomethylating Agents in the Gimema AML2320 Observational Trial

Free
Adriano Venditti, Alfonso Piciocchi, Stefano Soddu, Marco Frigeni, Raffaele Palmieri, Erika Borlenghi, Nicola Fracchiolla, Maria Paola Martelli, Ernesta Audisio, Giacomo Gianfaldoni, Calogero Vetro, Nicola di Rienzo, Daniela Esposito, Ambra Di Veroli, Carmine Selleri, Federica Gigli, Antonio Curti, Antonino Mulè, Catello Califano, Sara Bigliardi, Massimo Breccia, Claudio Fozza, Monica Bocchia, Albana Lico, Federico Simonetti, Elisabetta Pierdomenico, Francesco Buccisano, Maria Ilaria Del Principe, Luca Maurillo, Paola Fazi, Marco Vignetti, Felicetto Ferrara, Roberto Cairoli, Giuseppe Rossi, Alessandro Rambaldi
Journal: Blood
Blood (2023) 142 (Supplement 1): 1514.
https://doi.org/10.1182/blood-2023-178505
Published: 2023
Journal Articles

The Use of Next Generation Flow in Multiple Myeloma Patients: A Preliminary Real-Life Multicenter MRD Harmonization Experience

Free
Stefania Oliva, Elona Saraci, Valentina Trimarco, Marco Chiarini, Nunziatina Laura Parrinello, Renato Zambello, Iole Cordone, Tania Villanova, Serena Masi, Giovanni Rossi, Sara Marino, Anna Maria Triolo, Aldo Roccaro, Angelo Michele Carella, Francesco Buccisano, Angelo Belotti, Maria Irno Consalvo, Alessandra Romano, Alessia Tonini, Silvio Mercadante, Benedetto Bruno, Carolina Terragna, Elena Zamagni
Journal: Blood
Blood (2023) 142 (Supplement 1): 7161.
https://doi.org/10.1182/blood-2023-186536
Published: 2023
Journal Articles

Applicability of SIE/Sies/GITMO Fitness Criteria to Therapy-Related and AML-MRC Receiving CPX-351: Results from a Large, Retrospective, Multicentric, Observational Study

Free
Raffaele Palmieri, Fabio Guolo, Luana Fianchi, Felicetto Ferrara, Maria Paola Martelli, Michela Rondoni, Capria Saveria, Paola Minetto, Clara Minotti, Sofia Sciabolacci, Federica Pilo, Salvatore Perrone, Andrea Corbingi, Francesco Grimaldi, Giulia De Luca, Carla Fili, Caterina Alati, Francesco Mannelli, Federica Lessi, Francesco Marchesi, Lorenzo Brunetti, Debora Capelli, Anna Lina Piccioni, Calogero Vetro, Carla Mazzone, Alessandra Sperotto, Giovanni Luzi, Michelina Dargenio, Sabrina Mariani, Marco Cerrano, Antonino Mulè, Ambra Di Veroli, Cristina Papayannidis, Alessandro Isidori, Francesco Lanza, Michele Gottardi, Elisabetta Todisco, Livio Pagano, Roberto Massimo Lemoli, Francesco Buccisano, Adriano Venditti
Journal: Blood
Blood (2023) 142 (Supplement 1): 2891.
https://doi.org/10.1182/blood-2023-181142
Published: 2023
Journal Articles

Measurable Residual Disease Assessment in Patients with Acute Myeloid Leukemia Aged ≥60 Years Treated with a 10-Day Decitabine Schedule Versus Intensive Chemotherapy in the AML21 Study (NCT02172872)

Free
Adriano Venditti, Michal Kicinski, Ernesta Audisio, Mario Luppi, Gianluca Gaidano, Robin Foà, Anna Candoni, Andrea Mengarelli, Attilio Olivieri, Annalisa Imovilli, Maurizio Musso, Paolo De Fabritiis, Eliana Zuffa, Nicola Cascavilla, Agostino Tafuri, Maria Ilaria Del Principe, Stefan Suciu, Anne Giraut, Stéphanie Antunes, Pierre W. Wijermans, Michael Lübbert, Geert A. Huls, Marco Vignetti, Francesco Buccisano
Journal: Blood
Blood (2023) 142 (Supplement 1): 2948.
https://doi.org/10.1182/blood-2023-184851
Published: 2023
Journal Articles

The Added Value of Multi-State Modelling in Acute Myeloid Leukemia: The Gimema AML1310 Study Post-Hoc Analysis

Free
Alfonso Piciocchi, Valentina Arena, Monica Messina, Sonia Maria Orlando, Raffaele Palmieri, Luca Maurillo, Maria Ilaria Del Principe, Paola Fazi, Marco Vignetti, Francesco Buccisano, Adriano Venditti
Journal: Blood
Blood (2022) 140 (Supplement 1): 3192–3193.
https://doi.org/10.1182/blood-2022-158942
Published: 2022
Journal Articles

Real Life Feasibility of a Combined Clinical and Biological Fitness Assessment in Patients with Acute Myeloid Leukemia

Free
Raffaele Palmieri, Simona Iacobelli, Giovangiacinto Paterno, Moretti Federico, Elisa Buzzatti, Meddi Elisa, Savi Arianna, Gentiana Trotta, Flavia Mallegni, Maria Ilaria Del Principe, Luca Maurillo, Maria Teresa Voso, Adriano Venditti, Francesco Buccisano
Journal: Blood
Blood (2022) 140 (Supplement 1): 8961–8962.
https://doi.org/10.1182/blood-2022-159101
Published: 2022
Journal Articles

The Addition of Venetoclax to Induction Chemotherapy in No Low-Risk AML Patients: A Propensity Score-Matched Analysis of the Gimema AML1718 and AML1310 Trials

Free
Alfonso Piciocchi, Monica Messina, Marta Cipriani, Francesca Paoloni, Giorgia Simonetti, Raffaele Palmieri, Giovanni Marconi, Francesco Buccisano, Paola Fazi, Marco Vignetti, Giovanni Martinelli, Adriano Venditti
Journal: Blood
Blood (2022) 140 (Supplement 1): 137–138.
https://doi.org/10.1182/blood-2022-158890
Published: 2022
Journal Articles

AML: making residual disease more measurable

Free
Maria Teresa Voso, Francesco Buccisano
Journal: Blood
Blood (2022) 140 (5): 415–417.
https://doi.org/10.1182/blood.2022017138
Published: 2022
Journal Articles

2021 Update on MRD in acute myeloid leukemia: a consensus document from the European LeukemiaNet MRD Working Party

Free
Michael Heuser, Sylvie D. Freeman, Gert J. Ossenkoppele, Francesco Buccisano, Christopher S. Hourigan, Lok Lam Ngai, Jesse M. Tettero, Costa Bachas, Constance Baer, Marie-Christine Béné, Veit Bücklein, Anna Czyz, Barbara Denys, Richard Dillon, Michaela Feuring-Buske, Monica L. Guzman, Torsten Haferlach, Lina Han, Julia K. Herzig, Jeffrey L. Jorgensen, Wolfgang Kern, Marina Y. Konopleva, Francis Lacombe, Marta Libura, Agata Majchrzak, Luca Maurillo, Yishai Ofran, Jan Philippe, Adriana Plesa, Claude Preudhomme, Farhad Ravandi, Christophe Roumier, Marion Subklewe, Felicitas Thol, Arjan A. van de Loosdrecht, Bert A. van der Reijden, Adriano Venditti, Agnieszka Wierzbowska, Peter J. M. Valk, Brent L. Wood, Roland B. Walter, Christian Thiede, Konstanze Döhner, Gail J. Roboz, Jacqueline Cloos
Journal: Blood
Blood (2021) 138 (26): 2753–2767.
https://doi.org/10.1182/blood.2021013626
Published: 2021
Includes: Supplemental data
Journal Articles

Results of the 6-Year Follow-up of the Gimema AML1310 Trial: A Risk-Adapted, MRD-Directed Therapy for Young Adults with Newly Diagnosed Acute Myeloid Leukemia

Free
Adriano Venditti, Alfonso Piciocchi, Raffaele Palmieri, Valentina Arena, Anna Candoni, Valeria Calafiore, Lorella MA Melillo, Roberto Cairoli, Paolo De Fabritiis, Gabriella Storti, Prassede Salutari, Francesco Lanza, Giovanni Martinelli, Mario Luppi, Saveria Capria, Luca Maurillo, Maria Ilaria Del Principe, Giovangiacinto Paterno, Elisa Buzzatti, Maria Teresa Voso, Tiziana Ottone, Maria irno Consalvo, Paola Fazi, Marco Vignetti, William Arcese, Sergio Amadori, Francesco Buccisano
Journal: Blood
Blood (2021) 138 (Supplement 1): 2359.
https://doi.org/10.1182/blood-2021-147200
Published: 2021
Journal Articles

Validation of ELN2017 Risk Stratification in a Post-Hoc Analysis of the Prospective Biomarker-Based Gimema AML1310 Protocol

Free
Raffaele Palmieri, MD, Francesco Buccisano, MD, Alfonso Piciocchi, MS, Valentina Arena, MS, Anna Candoni, Lorella MA Melillo, MD, Valeria Calafiore, Roberto Cairoli, MD, Paolo De Fabritiis, MD, Gabriella Storti, Prassede Salutari, MD, Francesco Lanza, MD, Giovanni Martinelli, MD, Mario Luppi, Saveria Capria, MD, Luca Maurillo, Maria Ilaria Del Principe, Giovangiacinto Paterno, Maria Teresa Voso, MD, Tiziana Ottone, Serena Lavorgna, Paola Fazi, MD, Marco Vignetti, MD, William Arcese, MD PhD, Adriano Venditti, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 34–35.
https://doi.org/10.1182/blood-2020-139773
Published: 2020
Journal Articles

Clinical Relevance of- Limit of Detection (LOD) - Limit of Quantification (LOQ) - Based Flow Cytometry Approach for Measurable Residual Disease (MRD) Assessment in Acute Myeloid Leukemia (AML)

Free
Raffaele Palmieri, MD, Alfonso Piciocchi, Valentina Arena, MS, Luca Maurillo, Maria Ilaria Del Principe, Giovangiacinto Paterno, Tiziana Ottone, Mariadomenica Divona, Serena Lavorgna, Maria Irno Consalvo, Consuelo Conti, Cristina Attrotto, Daniela Fraboni, Maria Teresa Voso, MD, William Arcese, MD PhD, Adriano Venditti, MD, Francesco Buccisano, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 37–38.
https://doi.org/10.1182/blood-2020-139557
Published: 2020
Journal Articles

Leukemic Stem Cells Persistence Measured By Multiparametric Flow Cytometry Is a Biomarker of Poor Prognosis in Adult Patients with Acute Myeloid Leukemia

Free
Francesco Buccisano, MD, Raffaele Palmieri, MD, Maria Irno Consalvo, Alfonso Piciocchi, Luca Maurillo, Maria Ilaria Del Principe, Valentina Arena, Stefano Soddu, Ambra Di Veroli, MD, Giovangiacinto Paterno, Eleonora De Bellis, Daniela Fraboni, Consuelo Conti, Maria Teresa Voso, MD, William Arcese, Adriano Venditti
Journal: Blood
Blood (2019) 134 (Supplement_1): 2688.
https://doi.org/10.1182/blood-2019-128025
Published: 2019