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Chris Halsey
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Journal Articles

Characterising the leukaemic microenvironment in a mouse model of infant AML with prenatal KMT2A-MLLT3 expression

Free
Christopher Mullen, Ragini Medhi, Meryam Beniazza, Chris Halsey, Juerg Schwaller, Katrin Ottersbach
Journal: Blood
Blood (2025) 146 (Supplement 1): 3178.
https://doi.org/10.1182/blood-2025-3178
Published: 2025
Journal Articles

Serine/glycine starvation induces metabolic rewiring to uncover ATF4-driven therapeutic vulnerabilities in infant ALL

Free
Victoria Assmann, Jonathan Josephs-Spaulding, Lynn McGarry, Federico Bernuzzi, David Sumpton, Johan Vande Voorde, Leo Carlin, Oliver Maddocks, Katrin Ottersbach, Chris Halsey
Journal: Blood
Blood (2025) 146 (Supplement 1): 5084.
https://doi.org/10.1182/blood-2025-5084
Published: 2025
Journal Articles

Enhanced VLA4-dependent endothelial cell adhesion underpins the higher efficacy of CAR-iNKT over CAR-T cells in limiting leptomeningeal acute leukemia

Free
Ilia Leontari, Hongwei Ren, Klesti Karaxhuku, Bryan Lye, Kanagaraju Ponnusamy, Ekaterini Himonas, Irene Roberts, Aristeidis Chaidos, Chris Halsey, Cristina Lo Celso, Anastasios Karadimitris
Journal: Blood
Blood (2025) 146 (Supplement 1): 262.
https://doi.org/10.1182/blood-2025-262
Published: 2025
Journal Articles

Selenocysteine dependency renders central nervous system leukaemia therapeutically sensitive to ferroptosis

Free
Nikolai Gajic, Rhona Christie, Shirley Lam, Tobias Ackermann, Ekaterini Himonas, Jonathan Josephs-Spaulding, Anand Manoharan, Victoria Assmann, Jordan Martin, Alexander Collings, Karen Dunn, Engy Shokry, Alejandro Huerta Uribe, Sharon Burns, David O'Connor, Marc Mansour, David Sumpton, G. Vignir Helgason, Johan Vande Voorde, Saverio Tardito, Stephen Tait, Chris Halsey
Journal: Blood
Blood (2025) 146 (Supplement 1): 1526.
https://doi.org/10.1182/blood-2025-1526
Published: 2025
Journal Articles

NADPH controls a cell state vulnerability towards ferroptosis in acute lymphoblastic leukaemia

Free
Nikolai Gajic, Rhona Christie, Jordan Martin, Jonathan Josephs-Spaulding, Shirley Lam, Tobias Ackermann, Karen Dunn, Engy Shokry, Alejandro Huerta Uribe, Julie Irving, Frederick van Delft, Freya de Muyer, Panagiotis Ntziachristos, Johan Vande Voorde, David Sumpton, Saverio Tardito, Andrew Brown, Stephen Tait, Chris Halsey
Journal: Blood
Blood (2025) 146 (Supplement 1): 144.
https://doi.org/10.1182/blood-2025-144
Published: 2025
Journal Articles

GATA1 -mutant clones are frequent and often unsuspected in babies with Down syndrome: identification of a population at risk of leukemia

Free
Clinical Trials & Observations
Irene Roberts, Kate Alford, Georgina Hall, Gaetan Juban, Helen Richmond, Alice Norton, Grant Vallance, Kelly Perkins, Emanuele Marchi, Simon McGowan, Anindita Roy, Gillian Cowan, Mark Anthony, Amit Gupta, John Ho, Sabita Uthaya, Anna Curley, Shree Vishna Rasiah, Timothy Watts, Richard Nicholl, Alison Bedford-Russell, Raoul Blumberg, Angela Thomas, Brenda Gibson, Chris Halsey, Pek-Wan Lee, Sunit Godambe, Connor Sweeney, Neha Bhatnagar, Anne Goriely, Peter Campbell, Paresh Vyas
Journal: Blood
Blood (2013) 122 (24): 3908–3917.
https://doi.org/10.1182/blood-2013-07-515148
Published: 2013
Includes: Supplemental data