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Journal Articles

Off-the-shelf dual CAR-iNKT cell immunotherapy eradicates medullary and leptomeningeal high-risk KMT2A-rearranged leukemia

Open Access
Hongwei Ren, Natalina Elliott, Bryan Lye, Mohammad Umer Sharif Shohan, Joe Wilson Cross, Lucy May Field, Kanagaraju Ponnusamy, Siobhan Rice, Thomas Jackson, Ilia Leontari, Nouhad El Ouazzani, Rebecca Thomas, Sarah Inglott, Jack Bartram, Owen Smith, Professor, Jonathan Bond, Irene Roberts, Christina Halsey, Rachael Bashford-Rogers, Thomas A Milne, Anindita Roy, Anastasios Karadimitris
Journal: Blood
Blood blood.2025029302.
https://doi.org/10.1182/blood.2025029302
Published: 2025
Includes: Supplemental data
Journal Articles

Bispecific CAR-iNKT Immunotherapy for High Risk MLL-Rearranged Acute Lymphoblastic Leukemia

Free
Hongwei Ren, Natalina Elliott, Bryan Lye, Joe Cross, Lucy Field, Kanagaraju Ponnusamy, Irene Roberts, Christina Halsey, Thomas Arthur Milne, Anindita Roy, Anastasios Karadimitris
Journal: Blood
Blood (2023) 142 (Supplement 1): 766.
https://doi.org/10.1182/blood-2023-186442
Published: 2023
Journal Articles

Development of Novel Invariant TCR-Anchored Bispecific Engagers to Enhance Anti-Cancer Activity of iNKT Cells

Free
Klesti Karaxhuku, Kanagaraju Ponnusamy, Hongwei Ren, Bryan Lye, Ilia Leontari, Mehmood Zaidi, Farah Sabrin, Marco Bua, Maria Atta, Alexia Katsarou, Irene Roberts, Aristeidis Chaidos, Anastasios Karadimitris
Journal: Blood
Blood (2023) 142 (Supplement 1): 4828.
https://doi.org/10.1182/blood-2023-190598
Published: 2023
Journal Articles

Optimal, Off-the-Shelf, CAR-iNKT Cell Platform-Based Immunotherapy for Multiple Myeloma

Free
Kanagaraju Ponnusamy, Lyra Randzavola, Hongwei Ren, Klesti Karaxhuku, Bryan Lye, Dimitrios Leonardos, Reza Nadafi, Irene Sarkar, Ilia Leontari, Farah Sabrin, Mehmood Zaidi, Marco Bua, Maria Atta, Alexia Katsarou, Irene Roberts, Aristeidis Chaidos, Anastasios Karadimitris
Journal: Blood
Blood (2023) 142 (Supplement 1): 3459.
https://doi.org/10.1182/blood-2023-189905
Published: 2023
Journal Articles

Anti-T Cell Receptor Vβ Chain-Specific CAR-iNKT Cells As a Precise Strategy to Treat Mature T Cell Lymphomas

Free
Aileen G Rowan, Kanagaraju Ponnusamy, Hongwei Ren, Graham Phillip Taylor, Lucy Cook, Anastasios Karadimitris
Journal: Blood
Blood (2022) 140 (Supplement 1): 10257–10258.
https://doi.org/10.1182/blood-2022-165271
Published: 2022
Journal Articles

Pre-Clinical Evaluation of Allogeneic 'Off-the-Shelf' CAR-iNKT Cells Targeting CD19 (ALA-101)-Expressing Hematological Malignancies

Free
Kanagaraju Ponnusamy, Janani Kanagaraju, Yingxin Wang, Bryan Lye, Hongwei Ren, Uthayamalar Armugam, Sandhya Buchanan, Michael J Baker, Mini Bharathan, Anastasios Karadimitris
Journal: Blood
Blood (2022) 140 (Supplement 1): 12699–12700.
https://doi.org/10.1182/blood-2022-165516
Published: 2022