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Journal Articles

CUX1 restrains latent hematopoietic stem cell plasticity by suppressing stem cell-intrinsic inflammatory pathways

Tanner C Martinez, Matthew R. M. Jotte, Saira Khan, Angela Stoddart, Hunter Z. Blaylock, Ankit Malik, Megan E. McNerney

Blood blood.2024026815.

https://doi.org/10.1182/blood.2024026815

Published: 2025

Includes: Supplemental data

Journal Articles

Platelet Factor 4 (PF4) Regulates Hematopoietic Stem Cell Aging

Sen Zhang, Charles E. Ayemoba, Anna M. Di Staulo, Kenneth Joves, Chandani M. Patel, Eva Hin Wa Leung, Maura Lima Pereira Bueno, Xiaoping Du, Mortimer Poncz, Sang-Ging Ong, Claus Nerlov, Maria Maryanovich, Constantinos Chronis, Sandra Pinho

Blood blood.2024027432.

https://doi.org/10.1182/blood.2024027432

Published: 2025

Includes: Supplemental data

Journal Articles

An in vivo barcoded CRISPR-Cas9 screen identifies Ncoa4- mediated ferritinophagy as a dependence in Tet2 -deficient hematopoiesis

Justin Loke, Peter G. Kim, Thuy T. P. Nguyen, Meaghan Boileau, Marie McConkey, Aidan Miller, Wesley Shin, Christopher B. Hergott, Maria Ericsson, Anja Nordstrom, Paula Montero Llopis, Scott A. Armstrong, Joseph D. Mancias, Benjamin L. Ebert

Blood (2025) 146 (10): 1174–1186.

https://doi.org/10.1182/blood.2024028033

Published: 2025

Includes: Supplemental data

Journal Articles

Clinical and molecular features of immunodeficiency in patients with telomere biology disorders

Luiz Fernando Bazzo Catto, Nidhi Aggarwal, Ruba Shalhoub, Xiaoyang Ma, Ivana Darden, Tania Machado, Yue Zhang, Neelam R. Redekar, Natthakan Thongon, Simona Colla, Geraldine Aubert, Cynthia E. Dunbar, Colin O. Wu, Neal S. Young, Bhavisha A. Patel, Fernanda Gutierrez-Rodrigues, Emma M. Groarke

Blood (2025) 146 (10): 1187–1193.

https://doi.org/10.1182/blood.2024026735

Published: 2025

Includes: Supplemental data

Journal Articles

Correlates and consequences of clonal hematopoiesis expansion rate: a 16-year longitudinal study of 6976 women

Blood (2025) 146 (9): 1078–1087.

https://doi.org/10.1182/blood.2025028417

Published: 2025

Includes: Supplemental data

Journal Articles

RBM15-MKL1 fusion protein promotes leukemia via m6A methylation and Wnt pathway activation

Madeline Y. Mayday, Giulia Biancon, Manyi Wei, Christian Ramirez, Irene Moratti, Andreas P. Pintado-Urbanc, Jether Amos Espinosa, Mi Chen, Lin Wang, Matthew D. Simon, Yaara Ofir-Rosenfeld, Oliver Rausch, Toma Tebaldi, Stephanie Halene, Diane S. Krause

Blood (2025) 146 (9): 1096–1109.

https://doi.org/10.1182/blood.2024027712

Published: 2025

Includes: Supplemental data

Journal Articles

Platelet Heterogeneity: Variety Makes Immune and Vascular Function Better

Michael Malloy, Kathleen E McGrath, Craig N Morrell

Blood blood.2025028955.

https://doi.org/10.1182/blood.2025028955

Published: 2025

Journal Articles

Imaging mass cytometry reveals the order of events in the pathogenesis of immune-mediated aplastic anemia

Emma S. Pool, Sietse J. Luk, Marieke E. Ijsselsteijn, Vincent van Unen, Noel F. C. C. de Miranda, J. H. Frederik Falkenburg, Frits Koning, Mirjam H. M. Heemskerk, Jennifer M.-L. Tjon

Blood (2025) 146 (8): 951–963.

https://doi.org/10.1182/blood.2025028723

Published: 2025

Includes: Supplemental data

Journal Articles

T-ICAHT: grading and prognostic impact of thrombocytopenia after CAR T-cell therapy

Blood (2025) 146 (7): 834–846.

https://doi.org/10.1182/blood.2025028833

Published: 2025

Includes: Supplemental data

Journal Articles

PERK signaling maintains hematopoietic stem cell pool integrity under endoplasmic reticulum stress by promoting proliferation

Manxi Zheng, Qinlu Peng, Erin M. Kropp, Zhejuan Shen, Suxuan Liu, Zhengyou Yin, Sho Matono, Takao Iwawaki, Xiang Wang, Ken Inoki, Yang Mei, Qing Li, Lu Liu

Blood (2025) 146 (7): 806–818.

https://doi.org/10.1182/blood.2024027846

Published: 2025

Includes: Supplemental data

Journal Articles

Coordinated regulation of self-renewal and cell cycle during human lympho-myeloid lineage restriction

Fangwu Wang, Laura Gonzalez, Qiuyu Lian, Colin A. Hammond, Yasmine Y. M. Lau, Benjamin D. Simons, Martin Hirst, Connie J. Eaves

Blood (2025) 146 (6): 693–706.

https://doi.org/10.1182/blood.2024026936

Published: 2025

Includes: Supplemental data

Journal Articles

Defective neutrophil clearance in JAK2 V617F myeloproliferative neoplasms drives myelofibrosis via immune checkpoint CD24

Eman Khatib-Massalha, Christian A. Di Buduo, Agathe L. Chédeville, Ya-Hsuan Ho, Yexuan Zhu, Elodie Grockowiak, Yuki Date, Lam T. Khuat, Zijian Fang, José Quesada-Salas, Eva Carrillo Félez, Matteo Migliavacca, Isabel Montero, José A. Pérez-Simón, Alessandra Balduini, Simón Méndez-Ferrer

Blood (2025) 146 (6): 717–731.

https://doi.org/10.1182/blood.2024027455

Published: 2025

Includes: Supplemental data

Journal Articles

Metabolic Adaptation of Regenerative Hematopoiesis Depends on Docking-Independent Mitochondrial Connexin-43

Abhishek K Singh, Angelo D'Alessandro, Ashley Wellendorf, Daniel Gonzalez-Nieto, Matthew Kofron, Monika Dzieciatkowska, Leo Mejia, Luis Barrio, Marie-Dominique Filippi, Jose A. Cancelas

Blood blood.2024028079.

https://doi.org/10.1182/blood.2024028079

Published: 2025

Includes: Multimedia, Supplemental data

Journal Articles

Heterogeneity of high-potency multilineage hematopoietic stem cells and identification of “Super” transplantability

Blood (2025) 146 (5): 546–557.

https://doi.org/10.1182/blood.2024027872

Published: 2025

Includes: Supplemental data

Journal Articles

Delineating Mpl -dependent and -independent phenotypes of Jak2 V617F–positive MPNs in vivo

Nicolas Papadopoulos, Audrey Nédélec, Yacine Rahmani, Hosuk Ryou, Jean-Philippe Defour, Jens Rittscher, Daniel Royston, Stefan N. Constantinescu

Blood (2025) 146 (4): 482–495.

https://doi.org/10.1182/blood.2024026711

Published: 2025

Includes: Supplemental data

Journal Articles

CD99 Promotes Self-renewal in Hematopoietic Stem Cells and Leukemia Stem Cells by Regulating Protein Synthesis

Yuanyuan Ji, Yi Huang, Toby Thomas, Eda Gozel Kapti, Reiko Tachibana, Jacob Alan Lark, Iryna Berezniuk, Liang Guo, Mohamed A. E. Ali, Karin Mims, Benjamin Kroger, Wenhuo Hu, Christopher Y Park, Stephen S Chung

Blood blood.2024026271.

https://doi.org/10.1182/blood.2024026271

Published: 2025

Includes: Supplemental data

Journal Articles

Proteostasis disruption in inherited bone marrow failure syndromes

Helena Yu, Robert A. J. Signer

Blood (2025) 146 (3): 304–317.

https://doi.org/10.1182/blood.2024024956

Published: 2025

Journal Articles

An unbiased genomewide screen uncovers 7 genes that drive hematopoietic stem cell fate from mouse embryonic stem cells

Luis G. Palma, Gayathri M. Kartha, Maria Maqueda, Mercedes Barrero, Eric Canton, Arnau Iglesias, Jessica González, Patricia Herrero-Molinero, Raúl Torres-Ruiz, Bernhard Payer, Clara Bueno, Pablo Menéndez, Lluis Espinosa, Anna Bigas

Blood (2025) 146 (3): 328–340.

https://doi.org/10.1182/blood.2024027742

Published: 2025

Includes: Supplemental data

Journal Articles

ANKRD26-related thrombocytopenia 2 with a baseline increase in blasts: implications for clinical surveillance

Lara Wahlster, Lucy A. Godley, Jason X. Cheng, Michael W. Drazer, Christopher R. Reilly, Geraldine S. Pinkus, Jared H. Rowe, Nina Weichert-Leahey, R. Grant Rowe, Lev Gorfinkel, Karyn Brundige, Franziska Wachter, Luana Messa, Alan D. Michelson, Alan B. Cantor, Akiko Shimamura, Jacob R. Bledsoe

Blood (2025) 146 (2): 254–259.

https://doi.org/10.1182/blood.2024027368

Published: 2025

Includes: Supplemental data

Journal Articles

Loss of DCAF8 impairs hematopoietic stem cell function with cellular senescence via the DOCK11-CDC42 axis

Pengfei Xu, Xiuli Zhang, Donghe Li, Bo Jiao, Jiawei Nie, Yi Huang, Zhizhou Xia, Jiaoyang Li, Yuqing Dan, Xu Huang, Lei Yan, Rui Zhang, Wei Huang, Xinru Wang, Shiyu Ji, Yong Cang, Ruibao Ren, Ping Liu

Blood blood.2024027335.

https://doi.org/10.1182/blood.2024027335

Published: 2025

Includes: Supplemental data

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CUX1 restrains latent hematopoietic stem cell plasticity by suppressing stem cell-intrinsic inflammatory pathways

Platelet Factor 4 (PF4) Regulates Hematopoietic Stem Cell Aging

An in vivo barcoded CRISPR-Cas9 screen identifies Ncoa4- mediated ferritinophagy as a dependence in Tet2 -deficient hematopoiesis

Clinical and molecular features of immunodeficiency in patients with telomere biology disorders

Correlates and consequences of clonal hematopoiesis expansion rate: a 16-year longitudinal study of 6976 women

RBM15-MKL1 fusion protein promotes leukemia via m6A methylation and Wnt pathway activation

Platelet Heterogeneity: Variety Makes Immune and Vascular Function Better

Imaging mass cytometry reveals the order of events in the pathogenesis of immune-mediated aplastic anemia

T-ICAHT: grading and prognostic impact of thrombocytopenia after CAR T-cell therapy

PERK signaling maintains hematopoietic stem cell pool integrity under endoplasmic reticulum stress by promoting proliferation

Coordinated regulation of self-renewal and cell cycle during human lympho-myeloid lineage restriction

Defective neutrophil clearance in JAK2 V617F myeloproliferative neoplasms drives myelofibrosis via immune checkpoint CD24

Metabolic Adaptation of Regenerative Hematopoiesis Depends on Docking-Independent Mitochondrial Connexin-43

Heterogeneity of high-potency multilineage hematopoietic stem cells and identification of “Super” transplantability

Delineating Mpl -dependent and -independent phenotypes of Jak2 V617F–positive MPNs in vivo

CD99 Promotes Self-renewal in Hematopoietic Stem Cells and Leukemia Stem Cells by Regulating Protein Synthesis

Proteostasis disruption in inherited bone marrow failure syndromes

An unbiased genomewide screen uncovers 7 genes that drive hematopoietic stem cell fate from mouse embryonic stem cells

ANKRD26-related thrombocytopenia 2 with a baseline increase in blasts: implications for clinical surveillance

Loss of DCAF8 impairs hematopoietic stem cell function with cellular senescence via the DOCK11-CDC42 axis

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