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Journal Articles

Platelet activation and platelet-monocyte aggregate formation trigger tissue factor expression in patients with severe COVID-19

Eugenio D. Hottz, Isaclaudia G. Azevedo-Quintanilha, Lohanna Palhinha, Lívia Teixeira, Ester A. Barreto, Camila R. R. Pão, Cassia Righy, Sérgio Franco, Thiago M. L. Souza, Pedro Kurtz, Fernando A. Bozza, Patrícia T. Bozza

Blood (2020) 136 (11): 1330–1341.

https://doi.org/10.1182/blood.2020007252

Published: 2020

Includes: Supplemental data

Journal Articles

Talin-1 is the principal platelet Rap1 effector of integrin activation

Frederic Lagarrigue, David S. Paul, Alexandre R. Gingras, Andrew J. Valadez, Hao Sun, Jenny Lin, Monica N. Cuevas, Jailal N. Ablack, Miguel Alejandro Lopez-Ramirez, Wolfgang Bergmeier, Mark H. Ginsberg

Blood (2020) 136 (10): 1180–1190.

https://doi.org/10.1182/blood.2020005348

Published: 2020

Includes: Supplemental data

Journal Articles

The 14-3-3ζ–c-Src–integrin-β3 complex is vital for platelet activation

Chuanbin Shen, Ming Liu, Runjia Xu, Gan Wang, June Li, Pingguo Chen, Wenjing Ma, James Mwangi, Qiumin Lu, Zilei Duan, Zhiye Zhang, Fatima Zohra Dahmani, Daniel Thomas Mackeigan, Heyu Ni, Ren Lai

Blood (2020) 136 (8): 974–988.

https://doi.org/10.1182/blood.2019002314

Published: 2020

Includes: Supplemental data

Journal Articles

Integrin α6 mediates the drug resistance of acute lymphoblastic B-cell leukemia

Blood (2020) 136 (2): 210–223.

https://doi.org/10.1182/blood.2019001417

Published: 2020

Includes: Supplemental data

Journal Articles

Adhesion to fibronectin via α5β1 integrin supports expansion of the megakaryocyte lineage in primary myelofibrosis

Shinobu Matsuura, Cristal Reyna Thompson, Seng Kah Ng, Christina Marie Ward, Aikaterini Karagianni, Carla Mazzeo, Alessandro Malara, Alessandra Balduini, Katya Ravid

Blood (2020) 135 (25): 2286–2291.

https://doi.org/10.1182/blood.2019004230

Published: 2020

Includes: Supplemental data

Journal Articles

Integrin α9β1: a new target to fight thrombosis

Alexander Brill

Blood (2020) 135 (11): 787–788.

https://doi.org/10.1182/blood.2020004999

Published: 2020

Journal Articles

Targeting myeloid-cell specific integrin α9β1 inhibits arterial thrombosis in mice

Nirav Dhanesha, Manasa K. Nayak, Prakash Doddapattar, Manish Jain, Gagan D. Flora, Shigeyuki Kon, Anil K. Chauhan

Blood (2020) 135 (11): 857–861.

https://doi.org/10.1182/blood.2019002846

Published: 2020

Includes: Supplemental data

Journal Articles

Activation and suppression of hematopoietic integrins in hemostasis and immunity

Martijn A. Nolte, Coert Margadant

Blood (2020) 135 (1): 7–16.

https://doi.org/10.1182/blood.2019003336

Published: 2020

Journal Articles

Direct Visualization of Platelet Integrins Using ANTI-Transmembrane Domain Peptides Containing a BLUE Fluorescent Amino Acid

Karen Pei Yi Fong, PhD BS, Ismail A. Ahmed, PhD, Marco Mravic, B.S., M.S., Hyunil Jo, PhD, William F. DeGrado, PhD, Feng Gai, PhD, Joel S. Bennett, MD

Blood (2019) 134 (Supplement_1): 2344.

https://doi.org/10.1182/blood-2019-128363

Published: 2019

Journal Articles

Detection and Analysis of Gene Mutations in Patients with Glanzmann's Thrombasthenia

Boyang Sun, Donglei Zhang, Huiyuan Li, Xueqing Dou, Renchi Yang, MD

Blood (2019) 134 (Supplement_1): 2373.

https://doi.org/10.1182/blood-2019-129446

Published: 2019

Journal Articles

Cross-Strain Platelet Immunization in Selected Mouse Strains Recapitulates Clinical and Serologic Findings Typical of Post-Transfusion Purpura (PTP)

Daniel W. Bougie, PhD, Jessica Sutton, Richard H. Aster, MD

Blood (2019) 134 (Supplement_1): 2349.

https://doi.org/10.1182/blood-2019-126815

Published: 2019

Journal Articles

The Ribosomal Biogenesis Inhibitor CX-5461 Is an Anti-Cancer Therapeutic That Increases Platelet Count in Mice and in Humans

Amandeep Kaur, PhD, Katherine M Hannan, PhD, Samina Nazir, MSc, Kylee H Maclachlan, FRACP,FRCPA, Gretchen Poortinga, PhD, Si Ming Man, PhD, Simon Harrison, MBBS, MRCP, FRCPath, FRACP, PhD, Ross D Hannan, PhD, Elizabeth E. Gardiner, PhD

Blood (2019) 134 (Supplement_1): 2360.

https://doi.org/10.1182/blood-2019-121713

Published: 2019

Journal Articles

Clinical and Laboratory Features Associated with Flow Cytometric CD49f Expression in Pediatric B Cell Acute Lymphoblastic Leukemia

Eric McGinnis, MD BSc, David Yang, BMLSc, Nina Rolf, MD PhD, Gregor S. D. Reid, PhD, Chinten J. Lim, PhD, Suzanne M. Vercauteren, MD PhD FRCPC

Blood (2019) 134 (Supplement_1): 5209.

https://doi.org/10.1182/blood-2019-123590

Published: 2019

Journal Articles

Integrin-Mediated Adhesion to Extracellular Matrix Protein Fibronectin Drives Megakaryocytosis in JAK2 V617F+ Primary Myelofibrosis

Shinobu Matsuura, DVM,PhD, Cristal Reyna Thompson, PhD, Seng Kah Ng, PhD, Aikaterini Karagianni, MSc, Christina Ward Torres, PhD, Carla Silvana Mazzeo, PhD, Orly Leiva, MD, Alessandro Malara, PhD, Alessandra Balduini, MD, Katya Ravid, PhD DSc

Blood (2019) 134 (Supplement_1): 4205.

https://doi.org/10.1182/blood-2019-132124

Published: 2019

Journal Articles

Fibg 390-396A Limits Metastatic Potential Via a Mechanism Independent of Fibrin-Myeloid Cell Interactions, but Prospectively through the Disruption of FXIII-Mediated Fibrin Crosslinking

Brenton J Francisco, MD, Balkrishan Sharma, PhD, Leah A. Rosenfeldt, BS, Duaa Mureb, BS, Joseph S. Palumbo, MD

Blood (2019) 134 (Supplement_1): 2385.

https://doi.org/10.1182/blood-2019-131644

Published: 2019

Journal Articles

A Novel BCL-2/BCL-Xl Dual Inhibitor Overcomes Ibrutinib-Resistance Conferred By the Upregulation of Integrin Pathway and BCL-Xl

Jing Deng, PhD, Tingting Mao, MS, Xiaojing Huang, PhD, Li Rui, Guangfeng Wang, PhD, Douglas D. Fang, MD PhD, Dajun Yang, MD PhD, Yifan Zhai, MD PhD

Blood (2019) 134 (Supplement_1): 2573.

https://doi.org/10.1182/blood-2019-128708

Published: 2019

Journal Articles

PI3Kα/δ Inhibitor, Copanlisib, Inhibits Acute Lymphoblastic Leukemia Cell Growth, Increases Survival and Inhibits CNS Disease Progression in Leukemic Mice

Sarah Ridge, PhD, Hisayuki Yao, PhD, Trevor T Price, PhD, Andrew E Whiteley, PhD, Maegan Burns, Dorothy A. Sipkins, MD

Blood (2019) 134 (Supplement_1): 2758.

https://doi.org/10.1182/blood-2019-132097

Published: 2019

Journal Articles

High Surface Expression of CD49d (VLA-4) and CD79b Correlates with Acalabrutinib Resistance in Patients with Chronic Lymphocytic Leukemia (CLL)

Elena Bibikova, Brian Law, Tracy Clevenger, PhD, Jean Cheung, MS, Gary De Jesus, Michael Gulrajani, Kyoko Yamaguchi, Phuong Do, Kathleen Burke, PhD, Graham Brock, PhD, Veerendra Munugalavadla, PhD, Melanie M. Frigault, PhD, John C. Byrd, MD, Richard R. Furman, MD, Jennifer R. Brown, MD PhD, Todd Covey

Blood (2019) 134 (Supplement_1): 2571.

https://doi.org/10.1182/blood-2019-128872

Published: 2019

Journal Articles

Cell Adhesion of ALL to Stromal Cells May Mediate CAR T-Cell Resistance: A Novel Escape Mechanism for Immunotherapy

Hye Na Kim, Enzi Jiang, MD PhD, Ruan Yongsheng, MD, Heather Ogana, Nour Abdel-Azim, Justin Le, BS, Annie Luong, Halvard Bonig, MD, Nabil Ahmed, MD, Moghimi Babak, MD, Michael A. Pulsipher, MD, Deepa Bhojwani, MD, Alan S. Wayne, MD, Chintan Parekh, MBBS, Hisham Abdel-Azim, Nora Heisterkamp, Yong-Mi Kim, MD MPH, PhD

Blood (2019) 134 (Supplement_1): 2623.

https://doi.org/10.1182/blood-2019-132131

Published: 2019

Journal Articles

Reveal the Neutrophil: Elucidating the Role of a Neutrophil-Specific JAK2-V617F Mutation

Tobias Ronny Haage, MD, Andreas Johann Müller, Priyadharshini Arunachalam, Thomas Fischer, MD

Blood (2019) 134 (Supplement_1): 2965.

https://doi.org/10.1182/blood-2019-122660

Published: 2019

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Platelet activation and platelet-monocyte aggregate formation trigger tissue factor expression in patients with severe COVID-19

Talin-1 is the principal platelet Rap1 effector of integrin activation

The 14-3-3ζ–c-Src–integrin-β3 complex is vital for platelet activation

Integrin α6 mediates the drug resistance of acute lymphoblastic B-cell leukemia

Adhesion to fibronectin via α5β1 integrin supports expansion of the megakaryocyte lineage in primary myelofibrosis

Integrin α9β1: a new target to fight thrombosis

Targeting myeloid-cell specific integrin α9β1 inhibits arterial thrombosis in mice

Activation and suppression of hematopoietic integrins in hemostasis and immunity

Direct Visualization of Platelet Integrins Using ANTI-Transmembrane Domain Peptides Containing a BLUE Fluorescent Amino Acid

Detection and Analysis of Gene Mutations in Patients with Glanzmann's Thrombasthenia

Cross-Strain Platelet Immunization in Selected Mouse Strains Recapitulates Clinical and Serologic Findings Typical of Post-Transfusion Purpura (PTP)

The Ribosomal Biogenesis Inhibitor CX-5461 Is an Anti-Cancer Therapeutic That Increases Platelet Count in Mice and in Humans

Clinical and Laboratory Features Associated with Flow Cytometric CD49f Expression in Pediatric B Cell Acute Lymphoblastic Leukemia

Integrin-Mediated Adhesion to Extracellular Matrix Protein Fibronectin Drives Megakaryocytosis in JAK2 V617F+ Primary Myelofibrosis

Fibg 390-396A Limits Metastatic Potential Via a Mechanism Independent of Fibrin-Myeloid Cell Interactions, but Prospectively through the Disruption of FXIII-Mediated Fibrin Crosslinking

A Novel BCL-2/BCL-Xl Dual Inhibitor Overcomes Ibrutinib-Resistance Conferred By the Upregulation of Integrin Pathway and BCL-Xl

PI3Kα/δ Inhibitor, Copanlisib, Inhibits Acute Lymphoblastic Leukemia Cell Growth, Increases Survival and Inhibits CNS Disease Progression in Leukemic Mice

High Surface Expression of CD49d (VLA-4) and CD79b Correlates with Acalabrutinib Resistance in Patients with Chronic Lymphocytic Leukemia (CLL)

Cell Adhesion of ALL to Stromal Cells May Mediate CAR T-Cell Resistance: A Novel Escape Mechanism for Immunotherapy

Reveal the Neutrophil: Elucidating the Role of a Neutrophil-Specific JAK2-V617F Mutation

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