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Tobias Dechow
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Journal Articles

Long-Term Outcome of a Prospective Randomized Trial Comparing Continuous Lenalidomide/Dexamethasone with Lenalidomide/Dexamethasone Induction, MEL140 with Autologous Blood Stem Cell Transplantation and Single Agent Lenalidomide Maintenance in Patients of Age 60-75 Years with Newly Diagnosed Multiple Myeloma

Christian Straka, Kerstin Schaefer-Eckart, Bernd Hertenstein, Florian Bassermann, Hans Salwender, Christian Langer, Jan Krönke, Miriam Kull, Georgia Schilling, Aneta Schieferdecker, Monika Engelhardt, Stefan Knop, Julia Reusch, Wolf Roesler, Bernd Metzner, Holger Hebart, Albrecht Reichle, Matthias Grube, Norbert Frickhofen, Christian Gerecke, Stephan Fuhrmann, Wolfram Jung, Martin Gramatzki, Thomas Decker, Tobias Dechow, Jochen Greiner, Tim H. Brümmendorf, Juliana Ababei, Ivana von Metzler, Ralph Naumann, Elisabeth Fritz, Marcus Hentrich, Peter Bojko, Thomas Kubin, Christian Schmidt, Martin Kaufmann, Burkhard Schmidt, Axel Hinke, Hermann Einsele
Journal: Blood
Blood (2022) 140 (Supplement 1): 287–288.
https://doi.org/10.1182/blood-2022-159357
Published: 2022
Journal Articles

Patterns of Renal Recovery and Toxicity with Novel Agent-Based Induction Triplets in Newly Diagnosed Multiple Myeloma - an Analysis of Two Prospective Studies By the German DSMM Myeloma Study Group

Friederike Bachmann, MD, Swantje Held, Monika Engelhardt, MD, Christian Langer, MD, Denise Wolleschak, Janik Fleissner, Lars-Olof Mügge, MD, Heinz Duerk, MD PhD, Martin Schreder, MD, Kerstin Schaefer-Eckart, MD, Igor-Wolfgang Blau, MD PhD, Martin Gramatzki, MD, Peter Liebisch, MD, Albrecht Reichle, MD, Ivana Metzler, MD, Florian Bassermann, MD PhD, Bernd Metzner, MD PhD, Christoph Röllig, MD MSC, Bernd Hertenstein, Tobias Dechow, Wolfram Jung, MD, Helmut Ostermann, MD, Holger Hebart, Georg Maschmeyer, MD, Hans Jürgen Salwender, MD, Marie von Lilienfeld-Toal, MD, Kai-Uwe Eckardt, MD, Christian Straka, MD PhD, Hermann Einsele, MD, Stefan Knop
Journal: Blood
Blood (2019) 134 (Supplement_1): 1840.
https://doi.org/10.1182/blood-2019-125235
Published: 2019
Journal Articles

Lenalidomide, Adriamycin and Dexamethasone (RAD) Versus Bortezomib, Lenalidomide and Dexamethasone (VRD) in Newly Diagnosed Multiple Myeloma (MM) - Post-Induction Response and MRD Results By Flow Cytometry and NGS from a Phase 3 Randomized Controlled Clinical Trial (RCT)

Thomas Stübig, MD, Christian Langer, MD, Monika Engelhardt, MD, Lars-Olof Mügge, MD, Florian Bassermann, MD PhD, Martin Schreder, MD, Kerstin Schäfer-Eckart, MD, Igor Wolfgang Blau, Denise Wolleschak, Albrecht Reichle, MD, Ivana Metzler, MD, Bernd Metzner, MDPhD, Christoph Rollig, MD MSC, Bernd Hertenstein, MD, Heinz Dürk, Harald Biersack, MD, Helge Menzel, MD, Tobias Dechow, Jan Schleicher, Martin Gramatzki, MD, Tim H. Brümmendorf, MD, Stephan Fuhrmann, Max Bittrich, MD, Franziska Appelt, Martina Müller, Jan Krönke, MD, Julia Reusch, Christian Schmidt, MD, Monika Brüggemann, MD, Swantje Held, Stefan Knop, Hermann Einsele, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1979.
https://doi.org/10.1182/blood-2018-99-116067
Published: 2018
Journal Articles

Results of the Randomized Phase II Study Decider (AMLSG 14-09) Comparing Decitabine (DAC) with or without Valproic Acid (VPA) and with or without All- Trans Retinoic Acid (ATRA) Add-on in Newly Diagnosed Elderly Non-Fit AML Patients

Michael Lübbert, MD, Olga Grishina, Claudia Schmoor, Richard F. Schlenk, MD, Edgar Jost, Jürgen Krauter, MD, Michael Heuser, MD, Felicitas Thol, MD, Marcus M. Schittenhelm, Helmut R. Salih, Andrea Kündgen, MD, Ulrich Germing, Katharina Götze, Hans-Walter Lindemann, Carsten Müller-Tidow, Gerhard Heil, Gesine Bug, Carsten Schwänen, Aristoteles Giagounidis, Sebastian Scholl, Andreas Neubauer, Wolfram Brugger, Maike de Wit, Sebastian Schroll, Stephan Kremers, Elisabeth Lange, MD, Johannes Kullmer, Dirk Behringer, Matthias Egger, Irmgard Dresel, Tobias Dechow, Dietger Niederwieser, MD, Maxi Wass, Annette M. May, Ralph Wäsch, MD, Konstanze Döhner, Arnold Ganser, MD, Björn Hackanson, Hartmut Döhner, MD
Journal: Blood
Blood (2016) 128 (22): 589.
https://doi.org/10.1182/blood.V128.22.589.589
Published: 2016
Journal Articles

Constitutive gp130-JAK-STAT3 Signaling Induces a Plasma Cell Disorder Representing Genetic and Clinical Features of Human Myeloma – a Novel in Vivo Model for the Patient Subgroup Characterized By a STAT3 Target Gene Signature

Sabine Steidle, MD, Tobias Dechow, MD, Katharina Götze, Martina Rudelius, MD, Konstanze Pechloff, PhD, Kerstin Behnke, Lars Bullinger, MD PhD, Falko Fend, MD, Soberon Valeria, PhDstudent, Marc Schmidt-Supprian, PhD, Florian Bassermann, MD, Jürgen Ruland, MD, Christian Peschel, MD, Ulrich Keller, MD
Journal: Blood
Blood (2014) 124 (21): 648.
https://doi.org/10.1182/blood.V124.21.648.648
Published: 2014
Journal Articles

Multicenter Phase II Trial of Bendamustine, Lenalidomide and Dexamethasone (BRd) As 2 nd -Line Therapy for Multiple Myeloma

Ulrich JM Mey, Wolfram Brugger, MD, Mario Bargetzi, Heike Schwarb, MD, Andreas Schwarzer, MD, Tobias Dechow, MD, Paul Jehner, MD, Jacqueline Rauh, MD, Christian J. Taverna, MD, Mathias Schmid, MD, Martin Schmidt-Hieber, MD, Steffen Doerfel, Natalie Fischer, MD, Axel Ruefer, MD, Carsten Ziske, MD, Wolfgang Knauf, MD, Arnd Nusch, MD, Richard Cathomas, MD, Roger von Moos, MD, Elke Hiendlmeyer, Felicitas Hitz, MD, Christoph Driessen, MD
Journal: Blood
Blood (2014) 124 (21): 4779.
https://doi.org/10.1182/blood.V124.21.4779.4779
Published: 2014
Journal Articles

Lenalidomide with Low-Dose Dexamethasone (Rd) Continuously Versus Rd Induction, Tandem MEL140 with Autologous Transplantation and Lenalidomide Maintenance: Planned Interim Analysis of a Prospective Randomized Trial in Patients 60-75 Years of Age with Multiple Myeloma

Christian Straka, MD, Kerstin Schaefer-Eckart, MD, Florian Bassermann, MD, Hansen Timon, MD, Bernd Hertenstein, MD, Christian Langer, MD, Hans Salwender, MD, Stefan Knop, MD, Monika Engelhardt, MD, Martin Kropff, MD, Wolf Roesler, MD, Thomas Decker, MD, Holger Hebart, MD, Norbert Frickhofen, MD, Albrecht Reichle, Christian Gerecke, MD, Bernd Metzner, Else Heidemann, MD, Tim H Brummendorf, MD, Juliane Ababei, MD, Wolfram E Jung, MD, Martin Gramatzki, MD, Marcus Hentrich, MD, Peter Bojko, MD, Ivana von Metzler, MD, Martin Kaufmann, MD, Ralph Naumann, MD, Thomas Kubin, MD, Burkhard Schmidt, MD, Jochem Walther, MD, Tobias Dechow, MD, Hannes Wandt, MD, Brigitte Schnabel, Axel Hinke, PhD, Hermann Einsele
Journal: Blood
Blood (2014) 124 (21): 3969.
https://doi.org/10.1182/blood.V124.21.3969.3969
Published: 2014
Journal Articles

Prospective Randomized Trial of Len/Dex Induction Followed by Tandem MEL140 with Autologous Blood Stem Cell Transplantation and Len Maintenance Versus Continued Therapy with Len/Dex in Myeloma Patients Age 60–75 Years: Protocol-Defined Safety Analysis After 100 Patients

Christian Straka, Kerstin Schäfer-Eckart, Florian Bassermann, Bernd Hertenstein, Monika Engelhardt, Hans Salwender, MD, Wolf Rösler, Christian Langer, Georgia Schilling, Stefan Knop, Tim H Brümmendorf, Bernd Metzner, Holger Hebart, Albrecht Reichle, Norbert Frickhofen, MD, Else Heidemann, Juliana Ababei, Christian Gerecke, Wolfram Jung, Martin Gramatzki, Thomas Decker, Martin Kropff, MD, Ralph Naumann, Marcus Hentrich, Jochem Walther, Peter Bojko, Tobias Dechow, Hannes Wandt, Axel Hinke, Hermann Einsele
Journal: Blood
Blood (2012) 120 (21): 2012.
https://doi.org/10.1182/blood.V120.21.2012.2012
Published: 2012
Journal Articles

RAD (Lenalidomide, Adriamycin and Dexamethasone) Is a Novel and Very Effective Induction Regimen in Newly Diagnosed Multiple Myeloma Preceding a Risk-Adjusted Transplant Strategy,

Stefan Knop, MD, Christian Langer, MD, Monika Engelhardt, MD, Lars O Muegge, MD, Christoph Röllig, Albrecht Reichle, MD, Martin Gramatzki, Wolf Rösler, MD, Hannes Wandt, MD, Bernd Hertenstein, MD, Susanne Höppner, MD, Helmut Ostermann, MD, Isrid Sturm, MD, Tobias Dechow, MD, Mark Ringhoffer, MD, Marianne Sauerwein, MD, Hermann Einsele, MD, Ralf Bargou, MD
Journal: Blood
Blood (2011) 118 (21): 3967.
https://doi.org/10.1182/blood.V118.21.3967.3967
Published: 2011
Journal Articles

[18F]FLT Is Superior to [18F]FDG to Early Predict Response to Specific Inhibitors of NPM-ALK-Dependent Pathways In a Human ALCL Xenograft Model

Nicolas Graf, MD, Zhoulei Li, Ken Herrmann, MD, Alexandra Junger, Daniel Weh, Christian Peschel, MD, Markus Schwaiger, MD, Andreas Buck, MD, Tobias Dechow, MD
Journal: Blood
Blood (2010) 116 (21): 2849.
https://doi.org/10.1182/blood.V116.21.2849.2849
Published: 2010
Journal Articles

The Efficacy and Safety of RAD (Lenalidomide, Adriamycin and Dexamethasone) In Newly Diagnosed Multiple Myeloma – First Results of a Phase II Trial by the German DSMM Group

Stefan Knop, MD, Christian Langer, MD, Monika Engelhardt, MD, Lars O Muegge, MD, Albrecht Reichle, MD, Christoph Röllig, MD, Martin Gramatzki, MD, Wolf Roesler, MD, Max S Topp, MD, Carmen Wesemeier, MD, Bernd Hertenstein, MD, Isrid Sturm, MD, Tobias Dechow, MD, Martin Kortüm, MD, Marianne Sauerwein, MD, Hermann Einsele, MD, Ralf Bargou, MD
Journal: Blood
Blood (2010) 116 (21): 1945.
https://doi.org/10.1182/blood.V116.21.1945.1945
Published: 2010
Journal Articles

Velcade, Intravenous Cyclophosphamide and Dexamethasone (VCD) Induction for Previously Untreated Multiple Myeloma (German DSMM XIa Trial).

Hermann Einsele, Peter Liebisch, Christian Langer, Martin Kropff, Hannes Wandt, Wolfram Jung, Nikolaus Kröger, Monika Engelhardt, Helmut Ostermann, Lars-Olof Mügge, Hans-Heinrich Wolf, Christina Hart, Bernd Metzner, Martin Kaufmann, Martin Gramatzki, Bernd Hertenstein, Thomas Fischer, Katja Weisel, Gottfried Dölken, Wolfram Brugger, Hella Gollasch, Georg Maschmeyer, Michael Pfreundschuh, Norbert Schmitz, Orhan Sezer, Else Heidemann, Elke Jäger, Christoph Kahl, Alexander Kiani, Tobias Dechow, Wolf Rösler, Jan Philipp Simon, Heinz Dürk, Karl Heinz Pflüger, Martin Bentz, Georg Hess, Hans-Guenther Mergenthaler, Christian Straka, Dirk Hempel, Hans-Jürgen Salwender, Günter Fingerle-Rowson, Stefan Knop
Journal: Blood
Blood (2009) 114 (22): 131.
https://doi.org/10.1182/blood.V114.22.131.131
Published: 2009
Journal Articles

Unraveling STAT Signaling in NPM/ALK-Induced Lymphoma: STAT3 but Not STAT5 Is Required for Lymphomagenesis in a Bone Marrow Transplantation Model Using Conditional Knockout Mice.

Tobias Dechow, Elisa Amon, Cornelius Miething, Rebekka Grundler, Nicole Schatz, Marcus Kremer, Wolfgang Reindl, Ingo Ringshausen, Christian Peschel, Justus Duyster
Journal: Blood
Blood (2009) 114 (22): 1969.
https://doi.org/10.1182/blood.V114.22.1969.1969
Published: 2009
Journal Articles

Molecular Mechanisms of JAK2V617F Oncogenic Activation: The JAK2- V617F Mutant Utilizes the SH2 Domain for Constitutive Kinase Activity in the Presence of Unstimulated Heterodimeric Cytokine Receptor.

Sivahari P Gorantla, M.Sc., Tobias Dechow, M.D., Rebekka Grundler, Ph.D, Christian Peschel, MD, Justus Duyster
Journal: Blood
Blood (2008) 112 (11): 175.
https://doi.org/10.1182/blood.V112.11.175.175
Published: 2008
Journal Articles

Dissecting Proto-Oncogenic PIM Serine/Threonine Kinases in FLT3-ITDInduced Leukemogenesis: PIM1 Regulates CXCL12/CXCR4-Mediated Homing and Migration

Christelle Gasser, Rebekka Grundler, Laurent Brault, Alec Bullock, Tobias Dechow, Martjin Nawijn, Sabine Woetzel, Sabine Ehret, Georgina Berridge, Anke Spoo, Christine Dierks, Andrea Biondi, Stefan Knapp, Justus Duyster, Juerg Schwaller
Journal: Blood
Blood (2008) 112 (11): 3796.
https://doi.org/10.1182/blood.V112.11.3796.3796
Published: 2008
Journal Articles

Role of SH2 Domain in JAK2-V617F Mediated Transformation.

Sivahari P. Gorantla, MSc, Tobias Dechow, M.D, Christian Peschel, M.D, Justus Duyster, M.D
Journal: Blood
Blood (2006) 108 (11): 3608.
https://doi.org/10.1182/blood.V108.11.3608.3608
Published: 2006