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Journal Articles

The PDI-ATF6-axis as a novel treatment target in CSF3R driven chronic neutrophilic leukemia (CNL)

Blood (2025) 146 (Supplement 1): 1453.

https://doi.org/10.1182/blood-2025-1453

Published: 2025

Journal Articles

Post allo-HCT menin-inhibition enhances graft-versus-leukemia effects by endogenous retrovirus induction in AML and T-cell activation

Blood (2025) 146 (Supplement 1): 5862.

https://doi.org/10.1182/blood-2025-5862

Published: 2025

Journal Articles

Tracing malignant precursor mutations and their cellular origins in blood and bone marrow of primary central nervous system lymphomas by ultrasensitive genomic profiling

Julia Kuehn, Christian Klingler, Samuel Weinschenk, Jurik Mutter, Fabian Hummel, Julian Rapp, Eliza Lauer, Lavanya Ranganathan, Sabine Bleul, Stefan Alig, Marco Prinz, Justus Duyster, Roman Sankowski, Maximilian Diehn, Ash Alizadeh, Elisabeth Schorb, Peter Reinacher, Florian Scherer

Blood (2025) 146 (Supplement 1): 458.

https://doi.org/10.1182/blood-2025-458

Published: 2025

Journal Articles

Long-term remissions in refractory ITP patients by daratumumab

Julian List, Tim Strüßmann, Jürgen Heinz, Ralph Wäsch, Justus Duyster, Jesus Duque Afonso, Reinhard Marks

Blood (2025) 146 (Supplement 1): 3032.

https://doi.org/10.1182/blood-2025-3032

Published: 2025

Journal Articles

Menin inhibition enhances graft-versus-leukemia effects by T-cell activation and endogenous retrovirus induction in AML

Blood blood.2025029712.

https://doi.org/10.1182/blood.2025029712

Published: 2025

Includes: Supplemental data

Journal Articles

Guiding Treatment and Clinical Management of Patients with CNS Lymphomas By Minimal-Invasive Detection of Circulating Tumor DNA in Cerebrospinal Fluid

Blood (2024) 144 (Supplement 1): 1583.

https://doi.org/10.1182/blood-2024-202943

Published: 2024

Journal Articles

CSF3R T618I Is Stabilized By Calnexin and Induces Unfolded Protein Response (UPR) and ER-Phagy: A Pro-Survival Pathway for Oncogenic Misfolded CSF3R Proteins in Chronic Neutrophilic Leukemia (CNL)

Alessandra Hartke, Julia Klotz, Axel Künstner, Anke Fähnrich, Hauke Busch, Timo Gemoll, Jasmin Osius, Steffen Koschmieder, Tim H. H. Brummendorf, Heike L. Pahl, Florian H. Heidel, Konstanze Döhner, Martin Griesshammer, Andreas Reiter, Justus Duyster, Nikolas C. C. von Bubnoff, Sivahari P. Gorantla

Blood (2024) 144 (Supplement 1): 1348.

https://doi.org/10.1182/blood-2024-202513

Published: 2024

Journal Articles

SMARCC1 Controls the Oncogenic NOTCH1 Transcriptional Program in T-Cell Acute Lymphoblastic Leukemia

Khalid Shoumariyeh, Xiaoyang Sun, Teresa Poggio, Geoffroy Andrieux, Tatjan Schmitz, Stephan de Bra, Omid Fotouhi, Sheikh Nizamuddin, Uta Sabine Sabine Martens, Justus Duyster, Marc Timmers, Melanie Boerries, Cornelius Miething

Blood (2024) 144 (Supplement 1): 5760.

https://doi.org/10.1182/blood-2024-210721

Published: 2024

Journal Articles

Elevating AML Treatment: Enhancing DNMT1 Inhibition Boosts HMA Therapy

Uta Sabine Martens, Desiree Melanie Redhaber, Geoffroy Andrieux, Usama-Ur Rehman, Michael Lübbert, Justus Duyster, Cornelius Miething

Blood (2024) 144 (Supplement 1): 5746.

https://doi.org/10.1182/blood-2024-210326

Published: 2024

Journal Articles

STAT5-Activating Oncogenes Drive Oncostatin M Production Causing T Cell Exhaustion and Suppressive Myeloid Cell Recruitment

Blood (2024) 144 (Supplement 1): 4119.

https://doi.org/10.1182/blood-2024-207654

Published: 2024

Journal Articles

Machine Learning Based Prediction of One Year Mortality after Allogeneic Hematopoietic Cell Transplantation (alloHCT) Highlights Importance of Pre-Transplant Immunocompetence

Thomas Meyer, Robert Meyer, Daniela Oelke, Ralph Wäsch, Justus Duyster, Jürgen Finke, Robert Zeiser, Claudia Wehr

Blood (2024) 144 (Supplement 1): 106.

https://doi.org/10.1182/blood-2024-199021

Published: 2024

Journal Articles

Modulation of the Tumor Microenvironment By CCL19 in Primary CNS Lymphomas

Blood (2024) 144 (Supplement 1): 856.

https://doi.org/10.1182/blood-2024-199257

Published: 2024

Journal Articles

SPARC Stabilizes Integrin α4-VCAM-1 Interactions and Is Regulated By Intracellular Rac in NPM1 -Mutated AML

Driti Ashok, Dennis Raith, Martin Helmstädter, Geoffroy Andrieux, Séverine Kayser, Sangya Chatterjee, Judith Treiber, Khalid Shoumariyeh, Tim Struessmann, Valentin Wenger, Julian Rapp, Jesus Duque Afonso, Michael Lübbert, Robert Zeiser, Melanie Boerries, Justus Duyster, Tanja Nicole Hartmann

Blood (2024) 144 (Supplement 1): 1298.

https://doi.org/10.1182/blood-2024-205323

Published: 2024

Journal Articles

FLT3-ITD Driven CMTM6 Expression Contributes to Immune Escape of Acute Myeloid Leukemia

Blood (2024) 144 (Supplement 1): 3392.

https://doi.org/10.1182/blood-2024-201449

Published: 2024

Journal Articles

The Effect of Ibrutinib on the Myeloid Cell Compartment in Central Nervous System Lymphoma Slice Cultures

Julia C. Kuehn, Nicolas N. Neidert, Junyi Zhang, Jurik A Mutter, Stefan K. Alig, Christian Klingler, Fabian Hummel, Sabine Bleul, Lavanya Ranganathan, Jürgen Beck, Marco Prinz, Maximilian Diehn, Ash A. Alizadeh, Justus Duyster, Roman Sankowski, Dieter Henrik Heiland, Florian Scherer

Blood (2024) 144 (Supplement 1): 4374.

https://doi.org/10.1182/blood-2024-199125

Published: 2024

Journal Articles

Identification of Ikaros As Novel Interaction Partner of Cyclin D1/CDK4 in MCL

Xiaoyang Sun, Stephan de Bra, Tatjana Schmitz, Stefan Tholen, Geoffroy Andrieux, Uta Sabine Sabine Martens, Melanie Boerries, Oliver Schilling, Justus Duyster, Cornelius Miething

Blood (2024) 144 (Supplement 1): 4365.

https://doi.org/10.1182/blood-2024-210877

Published: 2024

Journal Articles

Single-Center Experience of Decitabine/Venetoclax in Newly Diagnosed Older AML Patients with Non-Favorable Genetics: Bridging to Allo-HCT or Treatment Continuation

David Alber, Christoph Rummelt, Tim Strüßmann, Andrés Rettig, Valeria Shlyakhto, Paul La Rosée, Martin Henkes, Elizaveta Bubnova, Tobias Ma, Johanna Thomas, Gabriele Ihorst, Claudia Wehr, Reinhard Marks, Heiko Becker, Justus Duyster, Ralph Wäsch, Jürgen Finke, Michael Lübbert

Blood (2023) 142 (Supplement 1): 7091.

https://doi.org/10.1182/blood-2023-187581

Published: 2023

Journal Articles

Immune-Effector-Cell-Associated-Neurotoxicity-Syndrome (ICANS) Pathophysiology Is Mediated By Microglia TGF-β-Activated Kinase-1 Signaling

Janaki Manoja Vinnakota, Francesca Biavasco, Marius Schwabenland, Chintan Chhatbar, Rachael C Adams, Daniel Erny, Sandra Duquesne, Nadia El Khawanky, Henrike Salié, Dimitrios Athanassopoulos, Lukas Braun, Dominik Schmidt, Viktor Fetsch, Rebeka N. Javorniczky, Jenny N.H.G Ho, Reinhard Marks, Ralph Wäsch, Federico Simonetta, Geoffroy Andrieux, Dietmar Pfeifer, Gianni Monaco, Christian Capitini, Terry J. Fry, Thomas Blank, Bruce R Blazar, Eva-Maria Wagner Drouet, Matthias Theobald, Clemens Sommer, Matthias Stelljes, Christian Reicherts, Astrid Jeibmann, Jens Schittenhelm, Camelia-Maria Monoranu, Andreas Rosenwald, K. Martin Kortüm, Leo Rasche, Hermann Einsele, Philipp Tobias Meyer, Joachim Brumberg, Andreas Mackensen, Michael von Bergwelt-Baildon, Roland Coras, Nathalie L. Albert, Laura M. Bartos, Matthias Brendel, Adrien Holzgreve, Melanie Boerries, Crystal L. Mackall, Justus Duyster, Natalie Koehler, Felix Strübing, Bertram Bengsch, Marco Ruella, Marion Subklewe, Louisa von Baumgarten, Saar Gill, Marco Prinz, Robert Zeiser

Blood (2023) 142 (Supplement 1): 100.

https://doi.org/10.1182/blood-2023-184867

Published: 2023

Journal Articles

Long-Term Follow-up of AML Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation after Primary Induction Failure

Miriam Mozaffari Jovein, Gabriele Ihorst, Jesus Duque Afonso, Ralph Wäsch, Claudia Wehr, Hartmut Bertz, Justus Duyster, Robert Zeiser, Jürgen Finke, Florian Scherer

Blood (2023) 142 (Supplement 1): 3588.

https://doi.org/10.1182/blood-2023-179103

Published: 2023

Journal Articles

Early Prediction of Treatment Response By Circulating Tumor DNA Profiling in Patients with Diffuse Large B-Cell Lymphoma Receiving CAR T-Cell Therapy

Anna Katharina Foerster, Corinna Kronenthaler, Lavanya Ranganathan, Samuel Bandara, Corinna Woestmann, Stephanie Yaung, Sabine Bleul, Christian Klingler, Jan Mitschke, Julius Wehrle, Ralph Wäsch, Justus Duyster, Tim Struessmann, Jürgen Finke, Bowdoin Su, Reinhard Marks, Florian Scherer

Blood (2023) 142 (Supplement 1): 2987.

https://doi.org/10.1182/blood-2023-178871

Published: 2023

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The PDI-ATF6-axis as a novel treatment target in CSF3R driven chronic neutrophilic leukemia (CNL)

Post allo-HCT menin-inhibition enhances graft-versus-leukemia effects by endogenous retrovirus induction in AML and T-cell activation

Tracing malignant precursor mutations and their cellular origins in blood and bone marrow of primary central nervous system lymphomas by ultrasensitive genomic profiling

Long-term remissions in refractory ITP patients by daratumumab

Menin inhibition enhances graft-versus-leukemia effects by T-cell activation and endogenous retrovirus induction in AML

Guiding Treatment and Clinical Management of Patients with CNS Lymphomas By Minimal-Invasive Detection of Circulating Tumor DNA in Cerebrospinal Fluid

CSF3R T618I Is Stabilized By Calnexin and Induces Unfolded Protein Response (UPR) and ER-Phagy: A Pro-Survival Pathway for Oncogenic Misfolded CSF3R Proteins in Chronic Neutrophilic Leukemia (CNL)

SMARCC1 Controls the Oncogenic NOTCH1 Transcriptional Program in T-Cell Acute Lymphoblastic Leukemia

Elevating AML Treatment: Enhancing DNMT1 Inhibition Boosts HMA Therapy

STAT5-Activating Oncogenes Drive Oncostatin M Production Causing T Cell Exhaustion and Suppressive Myeloid Cell Recruitment

Machine Learning Based Prediction of One Year Mortality after Allogeneic Hematopoietic Cell Transplantation (alloHCT) Highlights Importance of Pre-Transplant Immunocompetence

Modulation of the Tumor Microenvironment By CCL19 in Primary CNS Lymphomas

SPARC Stabilizes Integrin α4-VCAM-1 Interactions and Is Regulated By Intracellular Rac in NPM1 -Mutated AML

FLT3-ITD Driven CMTM6 Expression Contributes to Immune Escape of Acute Myeloid Leukemia

The Effect of Ibrutinib on the Myeloid Cell Compartment in Central Nervous System Lymphoma Slice Cultures

Identification of Ikaros As Novel Interaction Partner of Cyclin D1/CDK4 in MCL

Single-Center Experience of Decitabine/Venetoclax in Newly Diagnosed Older AML Patients with Non-Favorable Genetics: Bridging to Allo-HCT or Treatment Continuation

Immune-Effector-Cell-Associated-Neurotoxicity-Syndrome (ICANS) Pathophysiology Is Mediated By Microglia TGF-β-Activated Kinase-1 Signaling

Long-Term Follow-up of AML Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation after Primary Induction Failure

Early Prediction of Treatment Response By Circulating Tumor DNA Profiling in Patients with Diffuse Large B-Cell Lymphoma Receiving CAR T-Cell Therapy

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