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Samuel John
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Journal Articles

Project EVOLVE: An international analysis of postimmunotherapy lineage switch, an emergent form of relapse in leukemia

Open Access
Sara K Silbert, Alexander W Rankin, Chloe N Hoang, Alexandra Semchenkova, Regina M Myers, Elena Zerkalenkova, PhD, Hao-Wei Wang, Alexandra E Kovach, Constance M Yuan, Dana Delgado Colon, Loic Vasseur, Alex Bataller, Samuel John, Kaylyn Utley Lyons, Barbara D. Friedes, Anna Alonso-Saladrigues, Hisham Abdel-Azim, Estelle Balducci, Ahmed Aljudi, Marie Balsat, D. Nathan Biery, Aghiad Chamdin, Bill H Chang, Raymund S Cuevo, MD, Barbara De Moerloose, David S. Dickens, Ulrich A Duffner, Nicolas Duployez, Firas El Chaer, Michelle Ann Elliott, Gabriele Escherich, Sneha Fernandes, Mandi R Fitzjohn, Zhubin J Gahvari, Stephan A. Grupp, Rui Rochelle He, M.D., Cynthia Harrison, Christopher Bruce Hergott, Emily M. Hsieh, Annette S Kim, Dennis John Kuo, Daniel P Larson, Benjamin J Lee, Thibaut TL Leguay, R. Coleman Lindsley, Abhishek A. Mangaonkar, Kerstin Mezger, Holly L Pacenta, Jing Pan, Marlie R. M. Provost, Latika Puri, Sunil Sudhir Raikar, Armando Jose Martinez, Isabella Quijada Bristol, Kyle Daniel Murphy, Lauren Reiman, Michele S Redell, Kelly Reed, Gabrielle Roth Guepin, Jeremy D Rubinstein, Süreyya Savaşan, Kristian T Schafernak, Alexandra McLean Stevens, Aimee C Talleur, Naomi Torres Carapia, Jacques Vargaftig, Anant Vatsayan, Matthias Wölfl, Lipng Zhao, Susana Rives, Vanessa A. Fabrizio, Koji Sasaki, Ibrahim Aldoss, Nicolas Boissel, Susan R Rheingold, Kara L Davis, Sara Ghorashian, Elad Jacoby, Alexander Popov, Adam Joseph Lamble, Nirali N Shah
Journal: Blood
Blood blood.2024026655.
https://doi.org/10.1182/blood.2024026655
Published: 2025
Includes: Supplemental data
Journal Articles

The Role of Gut Microbiota in Modulating Efficacy and Adverse Effects of CAR T-Cell Therapy in the Pediatric Population

Free
Zoe O'Connor, Ashley Bui, Laura Coughlin, Shuheng Gan, Samuel John, Nicole Poulides, Parastoo Sabaeifard, Xiaowei Zhan, Stephen Lim, Angelica Sanjuan, Theodore W. Laetsch, Andrew Y. Koh
Journal: Blood
Blood (2024) 144 (Supplement 1): 3429.
https://doi.org/10.1182/blood-2024-211415
Published: 2024
Journal Articles

Clinical Factors Associated with Prolonged Cytopenias after CD19 Chimeric Antigen Receptor T-Cell Therapy for Pediatric B-Cell Acute Lymphoblastic Leukemia

Free
Regina M. Myers, Yimei Li, Adam Lamble, Emily M. Hsieh, Samuel John, Gregory Dolan, Hongyan Liu, Lee Chen, Jennifer Sheppard, Amanda M. DiNofia, Colleen Annesley, Stephan A. Grupp, Deepa Bhojwani, Rebecca A. Gardner, Lia Gore, Susan R Rheingold, Nirali N. Shah, Michael A. Pulsipher
Journal: Blood
Blood (2024) 144 (Supplement 1): 4827.
https://doi.org/10.1182/blood-2024-202027
Published: 2024
Journal Articles

Role of B Cell Recovery in Relapse Risk and CD19 Phenotype Following Real-World Use of Tisagenlecleucel for Pediatric B-Acute Lymphoblastic Leukemia: A Multi-Institutional Retrospective Study

Free
Xiaopei Lily Zeng, Soyang Kwon, Anant Vatsayan, Christina Baggott, Snehit Prabhu, Samuel John, Holly L. Pacenta, Christine L. Phillips, Jenna Rossoff, Julie-An Talano, Amy Moskop, Michael R Verneris, Douglas D. Myers, Erin Marie Hall, Nicole A Karras, Challice L. Bonifant, Muna Qayed, Michelle L. Hermiston, Prakash Satwani, Christa Krupski, Amy K Keating, Susanne H.C. Baumeister, Vanessa A. Fabrizio, Vasant Chinnabhandar, Emily Egeler, Sharon Mavroukakis, Khanh Nguyen, Kevin J. Curran, Crystal L. Mackall, Theodore W. Laetsch, Liora Michal Schultz, Kevin O. McNerney
Journal: Blood
Blood (2024) 144 (Supplement 1): 2817.
https://doi.org/10.1182/blood-2024-211231
Published: 2024
Journal Articles

Establishing Costs for Commercial Chimeric Antigen Receptor T-Cell (Tisagenlecleucel; Kymriah) in Children and Young Adult B-Cell Acute Lymphoblastic Leukemia; A Merged Analysis from the Prwcc and PHIS

Free
Prakash Satwani, Karen Chao, Maria Lopez-Garcia, Matt Hall, Zhezhen Jin, Lena E Winestone, Danielle Novetsky Friedman, Rachel Phelan, Christina Baggott, Samuel John, Holly L. Pacenta, Theodore W. Laetsch, Christine L Phillips, Michael R Verneris, Vanessa A. Fabrizio, Amy Keating, Julie-An Talano, Amy Moskop, Susanne H.C. Baumeister, Muna Qayed, Doug Douglas Myers, Erin Marie Hall, Snehit Prabhu, Khanh Nguyen, Casey A Carr, Crystal L. Mackall, John K Lin, Jeremy Goldhaber-Fiebert, Liora Michal Schultz
Journal: Blood
Blood (2023) 142 (Supplement 1): 6912.
https://doi.org/10.1182/blood-2023-187462
Published: 2023
Journal Articles

Chimeric Antigen Receptor T Cells Targeting LILRB4, an Immunoreceptor Mediating T-Cell Suppression, Are Potently Effective in Multiple Myeloma

Free
Francesco Di Meo, Samuel John, Chengcheng Zhang, Ciara Louise L. Freeman, Fabiana Perna
Journal: Blood
Blood (2023) 142 (Supplement 1): 4804.
https://doi.org/10.1182/blood-2023-182022
Published: 2023
Journal Articles

LILRB4 Is a Novel Target for KMT2A Rearranged Acute Leukemia

Free
Caroline Smith, Ryan Huang, Jingjing Xie, Xiaoye Liu, Yubo He, Kathleen Ludwig, Laura Klesse, Chengcheng Zhang, Samuel John
Journal: Blood
Blood (2022) 140 (Supplement 1): 7423–7424.
https://doi.org/10.1182/blood-2022-168410
Published: 2022
Journal Articles

KMT2A Rearrangements Are Associated with Lineage Switch Following CD19 Targeting CAR T-Cell Therapy

Free
Adam J. Lamble, Regina M. Myers, Agne Taraseviciute, Samuel John, Bonnie Yates, Seth M. Steinberg, Jennifer Sheppard, Alexandra E. Kovach, Brent L. Wood, Michael Borowitz, Maryalice Stetler-Stevenson, Constance M. Yuan, Vinodh Pillai, Toni Foley, Perry Chung, Lee Chen, Daniel W. Lee, Colleen Annesley, Amanda M. DiNofia, Stephan A. Grupp, Michael R Verneris, Lia Gore, Theodore W. Laetsch, Deepa Bhojwani, Patrick A. Brown, Michael A. Pulsipher, Susan R. Rheingold, Rebecca A Gardner, Nirali N. Shah
Journal: Blood
Blood (2021) 138 (Supplement 1): 256.
https://doi.org/10.1182/blood-2021-153336
Published: 2021
Journal Articles

Real-World Outcomes for Pediatric and Young Adult Patients with Relapsed or Refractory (R/R) B-Cell Acute Lymphoblastic Leukemia (ALL) Treated with Tisagenlecleucel: Update from the Center for International Blood and Marrow Transplant Research (CIBMTR) Registry

Free
Samuel John, Michael A. Pulsipher, Amy Moskop, Zhen-Huan Hu, Christine L. Phillips, Erin Marie Hall, Steven P. Margossian, Sarah Nikiforow, Paul L. Martin, Benjamin Oshrine, Amy K. Keating, Rayne H. Rouce, Ranjan Tiwari, Santiago Redondo, Jennifer Willert, Abhijit Agarwal, Marcelo C Pasquini, Stephan A. Grupp
Journal: Blood
Blood (2021) 138 (Supplement 1): 428.
https://doi.org/10.1182/blood-2021-146393
Published: 2021
Journal Articles

HESTER: A Phase II Study Evaluating Efficacy and Safety of Tisagenlecleucel Reinfusion in Pediatric and Young Adult Patients with Acute Lymphoblastic Leukemia Experiencing Loss of B-Cell Aplasia

Free
Michael W Boyer, MD, Sonali Chaudhury, MBBS,MD, Kara L Davis, DO, Timothy Alan Driscoll, MD, Stephan A Grupp, MD PhD, Michelle Hermiston, MD PhD, Samuel John, MD, Amy K Keating, MD PhD, Christina Kovacs, BS, JD, Andrea Magley, BS, Gary Douglas Myers, MD, Christine L Phillips, MD, Michael A Pulsipher, MD, Das Purkayastha, PhD, Julie-An Talano, MD, Jennifer Willert, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 23–24.
https://doi.org/10.1182/blood-2020-136340
Published: 2020