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Mehdi Gharghabi
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Journal Articles

Temporally Controlled MYC Overexpression in Chronic Lymphocytic Leukemia Accelerates Progression and Promotes Large B Cell Lymphoma Transformation

Ethan C. Whipp, Krithik Tella, Aidan Macaskill, Steven Sher, Casey Cempre, Jean Truxall, Mehdi Gharghabi, Fang Hao, Alexander R. Marr, Madeline Halpin, Pearlly S. Yan, Jennifer A. Woyach, Rosa Lapalombella
Journal: Blood
Blood (2024) 144 (Supplement 1): 2978.
https://doi.org/10.1182/blood-2024-210328
Published: 2024
Journal Articles

The Hyperbolic NAMPT Inhibitor RPT1G Synergizes with BCL-2 Family Inhibitors and Helps Overcome Venetoclax Resistance in Acute Myeloid Leukemia Cells

Gregory Crimmins, Min Wu, Francis Roushar, Claudia F. Ramos Aguilar, Mehdi Gharghabi, Banumathi Cole, Rosa Lapalombella, Dennise A. De Jesús-Díaz
Journal: Blood
Blood (2024) 144 (Supplement 1): 4134.
https://doi.org/10.1182/blood-2024-197972
Published: 2024
Journal Articles

Brd4 Inhibition Abrogates Inflammation and Self-Renewal in a Murine Model of Tet2 Mutated Clonal Hematopoiesis

Alexander Marr, Madeline Halpin, Dominique Corbin, Britten Gordon, Samon Benrashid, Ethan C. Whipp, Mehdi Gharghabi, Jean Truxall, Olivia Cahn, Kristin L Koenig, Karilyn T. Larkin, Jennifer A. Woyach, Rosa Lapalombella, Nicole R. Grieselhuber
Journal: Blood
Blood (2023) 142 (Supplement 1): 4070.
https://doi.org/10.1182/blood-2023-179237
Published: 2023
Journal Articles

Cooperative Somatic Alterations in XPO1 and TNFAIP3 (A20) Promote Immune Modulation and Tissue Infiltration in Primary Mediastinal B Cell Lymphoma

Ethan C. Whipp, Janek S. Walker, Mehdi Gharghabi, Casey Cempre, Brandi Walker, Rosa Lapalombella
Journal: Blood
Blood (2023) 142 (Supplement 1): 2995.
https://doi.org/10.1182/blood-2023-189886
Published: 2023
Journal Articles

Genome-Wide CRISPR/Cas9 Knockout Screen Reveals Novel Gilteritinib Combinations Targeting Oxidative Phosphorylation and De-Novo Purine Biosynthesis Pathways for FLT3-ITD + Acute Myeloid Leukemia

Steven Sher, Pu Zhang, Lindsey Brinton, Mehdi Gharghabi, Katie Williams, Matthew Cannon, Janek S. Walker, Daniel Canfield, Larry Beaver, Casey B. Cempre, Hannah Phillips, Xuyong Chen, Pearlly S. Yan, Amy M. Lehman, Peggy Scherle, Min Wang, Kris Vaddi, Robert A. Baiocchi, Ruoning Wang, Deepa Sampath, Lapo Alinari, James S. Blachly, Rosa Lapalombella
Journal: Blood
Blood (2022) 140 (Supplement 1): 681–682.
https://doi.org/10.1182/blood-2022-165573
Published: 2022