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Journal Articles

Rebalancing Hemostasis in Hemophilia: Interplay between Antithrombin and Ancillary Thrombin Inhibitors

Allen Ma, Dougald M. Monroe, Maureane Hoffman

Blood (2024) 144 (Supplement 1): 2577.

https://doi.org/10.1182/blood-2024-203922

Published: 2024

Journal Articles

Emizicumab Promotes Factor Xa Generation on Activated Endothelium in a Blood Cell-Independent Manner

Patrick Ellsworth, Dougald Monroe, Maureane Hoffman, Nigel S Key

Blood (2021) 138 (Supplement 1): 3182.

https://doi.org/10.1182/blood-2021-148556

Published: 2021

Journal Articles

In Hemophilia Α Plasma Treated with Emicizumab, Factor IXa in Activated Prothrombin Complex Concentrates Is the Dominant Contributor to Enhanced Thrombin Generation

Dougald Monroe, PhD, Mirella Ezban, PhD, Maureane Hoffman, MD

Blood (2020) 136 (Supplement 1): 16–17.

https://doi.org/10.1182/blood-2020-139586

Published: 2020

Journal Articles

In Hemophilia Α Plasma Treated with Emicizumab, Factor IX Activation By Factor VIIa Drives Thrombin Generation

Dougald Monroe, PhD, Mirella Ezban, PhD, Maureane Hoffman, MD

Blood (2020) 136 (Supplement 1): 17.

https://doi.org/10.1182/blood-2020-139712

Published: 2020

Journal Articles

EPCR knockout: inflaming the discussion

Dougald Monroe, Maureane Hoffman

Blood (2020) 135 (25): 2201–2202.

https://doi.org/10.1182/blood.2020006001

Published: 2020

Journal Articles

Red blood cell microvesicles activate the contact system, leading to factor IX activation via 2 independent pathways

Denis F. Noubouossie, Michael W. Henderson, Micah Mooberry, Anton Ilich, Patrick Ellsworth, Mark Piegore, Sarah C. Skinner, Rafal Pawlinski, Ian Welsby, Thomas Renné, Maureane Hoffman, Dougald M. Monroe, Nigel S. Key

Blood (2020) 135 (10): 755–765.

https://doi.org/10.1182/blood.2019001643

Published: 2020

Includes: Supplemental data

Journal Articles

Characterization of a Novel Human Factor VIIa Chimera with Increased Tissue Factor-Independent Activity for Emergency Hemostasis

Ammon Fager, MD PhD, Maureane Hoffman, MD PhD, Dougald Monroe, PhD

Blood (2019) 134 (Supplement_1): 3623.

https://doi.org/10.1182/blood-2019-124428

Published: 2019

Journal Articles

Biochemical Characteristics of Emicizumab Activity with Factors IXa, X, and VIIa

Dougald Monroe, PhD, Maureane Hoffman, MD

Blood (2018) 132 (Supplement 1): 1167.

https://doi.org/10.1182/blood-2018-99-116888

Published: 2018

Journal Articles

Nitric Oxide Mediates Downregulation of Tissue Factor Expression in Primary Human Pericytes through a p38 MAPK Signaling Pathway

Laura Sommerville, PhD, Maureane Hoffman, MD

Blood (2018) 132 (Supplement 1): 2425.

https://doi.org/10.1182/blood-2018-99-119192

Published: 2018

Journal Articles

Abnormal joint and bone wound healing in hemophilia mice is improved by extending factor IX activity after hemarthrosis

Junjiang Sun, Baolai Hua, Eric W. Livingston, Sarah Taves, Peter B. Johansen, Maureane Hoffman, Mirella Ezban, Dougald M. Monroe, Ted A. Bateman, Paul E. Monahan

Blood (2017) 129 (15): 2161–2171.

https://doi.org/10.1182/blood-2016-08-734053

Published: 2017

Includes: Supplemental data

Journal Articles

Downregulation of Tissue Factor in Pericytes By a Protein Kinase C-Dependent Mechanism

Laura Sommerville, PhD, Kristen Gorman, Angela Crabtree, Maureane Hoffman, MD PhD

Blood (2015) 126 (23): 4637.

https://doi.org/10.1182/blood.V126.23.4637.4637

Published: 2015

Journal Articles

Endothelial Protein C Receptor Is Expressed on Procoagulant Platelets and Contributes to Factor VIIa Binding and Activity

Ammon M. Fager, MD PhD, Maureane Hoffman, MD PhD

Blood (2014) 124 (21): 4224.

https://doi.org/10.1182/blood.V124.21.4224.4224

Published: 2014

Journal Articles

Downregulation Of Tissue Factor Expression In Human Pericytes In An Endothelial Cell Co-Culture Model

Stacey A. Snyder, PhD, Maureane Hoffman, MD, PhD, Dougald Monroe, PhD, Samantha L. Lasater

Blood (2013) 122 (21): 3524.

https://doi.org/10.1182/blood.V122.21.3524.3524

Published: 2013

Journal Articles

Reversal Of Dabigatran Anticoagulation By a 4-Factor Prothrombin Complex Concentrate: Correlation Between Effects On Parameters Of Thrombin Generation and Hemostatic Effect In Vivo

Maureane Hoffman, MD, PhD, Zoya Volovyk, PhD, Dougald Monroe, PhD

Blood (2013) 122 (21): 3643.

https://doi.org/10.1182/blood.V122.21.3643.3643

Published: 2013

Journal Articles

The Impact of Factor IX Level on Thrombin Generation and Bleeding During Warfarin Anticoagulation

Yesim Dargaud, Maureane Hoffman, MD, PhD, Claude Negrier, MD, Leana Lefrapper, Dougald M. Monroe, III, PhD

Blood (2011) 118 (21): 541.

https://doi.org/10.1182/blood.V118.21.541.541

Published: 2011

Journal Articles

The Influence of Hemophilia on Wound Healing.

Maureane Hoffman, MD, PhD

Blood (2009) 114 (22): SCI-21.

https://doi.org/10.1182/blood.V114.22.SCI-21.SCI-21

Published: 2009

Journal Articles

Celecoxib Does Not Delay Cutaneous Wound Healing in Hemophilia B Mice.

Shan Pradhan, MD, Maureane Hoffman, MD, PhD, Dougald M. Monroe, III, PhD

Blood (2008) 112 (11): 1228.

https://doi.org/10.1182/blood.V112.11.1228.1228

Published: 2008

Journal Articles

FVIIa: you've come a long way, baby!

Maureane Hoffman

Blood (2008) 112 (8): 3002–3003.

https://doi.org/10.1182/blood-2008-08-171280

Published: 2008

Journal Articles

Perivascular tissue factor is down-regulated following cutaneous wounding: implications for bleeding in hemophilia

Anna G. McDonald, Katie Yang, Harold R. Roberts, Dougald M. Monroe, Maureane Hoffman

Blood (2008) 111 (4): 2046–2048.

https://doi.org/10.1182/blood-2007-05-092916

Published: 2008

Journal Articles

Tissue Factor Is Absent from Sites of Cutaneous Wounds: Implications for Bleeding in Hemophilia.

Anna G. McDonald, BS, Katherine Yang, Harold R. Roberts, MD, Dougald M. Monroe, PhD, Maureane Hoffman, MD, PhD

Blood (2006) 108 (11): 1803.

https://doi.org/10.1182/blood.V108.11.1803.1803

Published: 2006

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Rebalancing Hemostasis in Hemophilia: Interplay between Antithrombin and Ancillary Thrombin Inhibitors

Emizicumab Promotes Factor Xa Generation on Activated Endothelium in a Blood Cell-Independent Manner

In Hemophilia Α Plasma Treated with Emicizumab, Factor IXa in Activated Prothrombin Complex Concentrates Is the Dominant Contributor to Enhanced Thrombin Generation

In Hemophilia Α Plasma Treated with Emicizumab, Factor IX Activation By Factor VIIa Drives Thrombin Generation

EPCR knockout: inflaming the discussion

Red blood cell microvesicles activate the contact system, leading to factor IX activation via 2 independent pathways

Characterization of a Novel Human Factor VIIa Chimera with Increased Tissue Factor-Independent Activity for Emergency Hemostasis

Biochemical Characteristics of Emicizumab Activity with Factors IXa, X, and VIIa

Nitric Oxide Mediates Downregulation of Tissue Factor Expression in Primary Human Pericytes through a p38 MAPK Signaling Pathway

Abnormal joint and bone wound healing in hemophilia mice is improved by extending factor IX activity after hemarthrosis

Downregulation of Tissue Factor in Pericytes By a Protein Kinase C-Dependent Mechanism

Endothelial Protein C Receptor Is Expressed on Procoagulant Platelets and Contributes to Factor VIIa Binding and Activity

Downregulation Of Tissue Factor Expression In Human Pericytes In An Endothelial Cell Co-Culture Model

Reversal Of Dabigatran Anticoagulation By a 4-Factor Prothrombin Complex Concentrate: Correlation Between Effects On Parameters Of Thrombin Generation and Hemostatic Effect In Vivo

The Impact of Factor IX Level on Thrombin Generation and Bleeding During Warfarin Anticoagulation

The Influence of Hemophilia on Wound Healing.

Celecoxib Does Not Delay Cutaneous Wound Healing in Hemophilia B Mice.

FVIIa: you've come a long way, baby!

Perivascular tissue factor is down-regulated following cutaneous wounding: implications for bleeding in hemophilia

Tissue Factor Is Absent from Sites of Cutaneous Wounds: Implications for Bleeding in Hemophilia.

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