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Journal Articles

Blood coagulation factor IX: structural insights impacting hemophilia B therapy

Mettine H. A. Bos, Rianne E. van Diest, Dougald M. Monroe

Blood (2024) 144 (21): 2198–2210.

https://doi.org/10.1182/blood.2023023276

Published: 2024

Journal Articles

Rebalancing Hemostasis in Hemophilia: Interplay between Antithrombin and Ancillary Thrombin Inhibitors

Allen Ma, Dougald M. Monroe, Maureane Hoffman

Blood (2024) 144 (Supplement 1): 2577.

https://doi.org/10.1182/blood-2024-203922

Published: 2024

Journal Articles

Low Normal Levels of Factor V Enhance Thrombin Generation in Hemophilia a in a Tissue Factor Pathway Inhibitor Independent Manner

Megan P Jewell, Alexandra Bernal, Christine Baird, Marilyn Manco-Johnson, Dougald M. Monroe, Keith B. Neeves

Blood (2024) 144 (Supplement 1): 2579.

https://doi.org/10.1182/blood-2024-210722

Published: 2024

Journal Articles

Hypertonicity and/or Acidosis Induce Marked Rheological Changes Under Hypoxic Conditions in Sickle Trait Red Blood Cells

Patrick Ellsworth, Izabela Pawlinski, Rachel Sielaty, Anton Ilich, Chatphatai Moonla, Yuriy Prokopenko, Dougald M. Monroe, Rafal Pawlinski, Nigel S. Key

Blood (2023) 142 (Supplement 1): 1113.

https://doi.org/10.1182/blood-2023-187112

Published: 2023

Journal Articles

Red blood cell microvesicles activate the contact system, leading to factor IX activation via 2 independent pathways

Denis F. Noubouossie, Michael W. Henderson, Micah Mooberry, Anton Ilich, Patrick Ellsworth, Mark Piegore, Sarah C. Skinner, Rafal Pawlinski, Ian Welsby, Thomas Renné, Maureane Hoffman, Dougald M. Monroe, Nigel S. Key

Blood (2020) 135 (10): 755–765.

https://doi.org/10.1182/blood.2019001643

Published: 2020

Includes: Supplemental data

Journal Articles

Abnormal joint and bone wound healing in hemophilia mice is improved by extending factor IX activity after hemarthrosis

Junjiang Sun, Baolai Hua, Eric W. Livingston, Sarah Taves, Peter B. Johansen, Maureane Hoffman, Mirella Ezban, Dougald M. Monroe, Ted A. Bateman, Paul E. Monahan

Blood (2017) 129 (15): 2161–2171.

https://doi.org/10.1182/blood-2016-08-734053

Published: 2017

Includes: Supplemental data

Journal Articles

In vitro activation of coagulation by human neutrophil DNA and histone proteins but not neutrophil extracellular traps

Denis F. Noubouossie, Matthew F. Whelihan, Yuan-Bin Yu, Erica Sparkenbaugh, Rafal Pawlinski, Dougald M. Monroe, Nigel S. Key

Blood (2017) 129 (8): 1021–1029.

https://doi.org/10.1182/blood-2016-06-722298

Published: 2017

Journal Articles

Adding some muscle to blood coagulation

Dougald M. Monroe

Blood (2016) 128 (14): 1786–1787.

https://doi.org/10.1182/blood-2016-08-729533

Published: 2016

Journal Articles

The Effect of Prophylactic Recombinant Factor IX and Glycopegylated Factor IX to Normalize Articular Wound Healing Following Hemarthrosis Examined in Hemophilia B Mice

Junjiang Sun, MD, Eric Livingston, Tom Knudsen, DVM, PhD, Dougald M. Monroe, III, PhD, Mirella Ezban, PhD, Ted Bateman, PhD, Paul E. Monahan, MD

Blood (2015) 126 (23): 549.

https://doi.org/10.1182/blood.V126.23.549.549

Published: 2015

Journal Articles

Purified DNA, but Not Neutrophil Extracellular Traps (NETs), Promotes Contact Activation of Coagulation

Denis Noubouossie, MD PhD, Matthew F Whelihan, PhD, Dougald M. Monroe, III, PhD, Nigel S. Key, MB, ChB

Blood (2015) 126 (23): 767.

https://doi.org/10.1182/blood.V126.23.767.767

Published: 2015

Journal Articles

Polyphosphates rock! A role in thrombosis?

Dougald M. Monroe

Blood (2015) 126 (12): 1403–1404.

https://doi.org/10.1182/blood-2015-07-657148

Published: 2015

Journal Articles

Differential contribution of FXa and thrombin to vascular inflammation in a mouse model of sickle cell disease

Erica M. Sparkenbaugh, Pichika Chantrathammachart, Jacqueline Mickelson, Joanne van Ryn, Robert P. Hebbel, Dougald M. Monroe, Nigel Mackman, Nigel S. Key, Rafal Pawlinski

Blood (2014) 123 (11): 1747–1756.

https://doi.org/10.1182/blood-2013-08-523936

Published: 2014

Includes: Supplemental data

Journal Articles

Partial Reversal of Dabigatran Effect by a Prothrombin Complex Concentrate in a Model of Thrombin Generation

Maureane R. Hoffman, MD, PhD, Zoya Volovyk, PhD, Dougald M. Monroe, III, PhD

Blood (2012) 120 (21): 3420.

https://doi.org/10.1182/blood.V120.21.3420.3420

Published: 2012

Journal Articles

Factor VIIa: on its own and loving it

Dougald M. Monroe

Blood (2012) 120 (4): 705–707.

https://doi.org/10.1182/blood-2012-05-429654

Published: 2012

Journal Articles

The Impact of Factor IX Level on Thrombin Generation and Bleeding During Warfarin Anticoagulation

Yesim Dargaud, Maureane Hoffman, MD, PhD, Claude Negrier, MD, Leana Lefrapper, Dougald M. Monroe, III, PhD

Blood (2011) 118 (21): 541.

https://doi.org/10.1182/blood.V118.21.541.541

Published: 2011

Journal Articles

Increased Platelet Binding of NN1731, a Factor VIIa Variant with Enhanced Tissue Factor-Independent Activity.

Maureane R. Hoffman, MD, PhD, Egon Persson, PhD, Mirella Ezban, Dougald M. Monroe, III, PhD

Blood (2010) 116 (21): 1133.

https://doi.org/10.1182/blood.V116.21.1133.1133

Published: 2010

Journal Articles

Celecoxib Does Not Delay Cutaneous Wound Healing in Hemophilia B Mice.

Shan Pradhan, MD, Maureane Hoffman, MD, PhD, Dougald M. Monroe, III, PhD

Blood (2008) 112 (11): 1228.

https://doi.org/10.1182/blood.V112.11.1228.1228

Published: 2008

Journal Articles

Perivascular tissue factor is down-regulated following cutaneous wounding: implications for bleeding in hemophilia

Anna G. McDonald, Katie Yang, Harold R. Roberts, Dougald M. Monroe, Maureane Hoffman

Blood (2008) 111 (4): 2046–2048.

https://doi.org/10.1182/blood-2007-05-092916

Published: 2008

Journal Articles

Restoring Initial Thrombin Generation Does Not Normalize Cutaneous Wound Healing in Hemophilia B.

Anna G. McDonald, BS, Maureane Hoffman, MD, PhD, Ulla Hedner, MD, Harold R. Roberts, MD, Dougald M. Monroe, PhD

Blood (2006) 108 (11): 1030.

https://doi.org/10.1182/blood.V108.11.1030.1030

Published: 2006

Journal Articles

Tissue Factor Is Absent from Sites of Cutaneous Wounds: Implications for Bleeding in Hemophilia.

Anna G. McDonald, BS, Katherine Yang, Harold R. Roberts, MD, Dougald M. Monroe, PhD, Maureane Hoffman, MD, PhD

Blood (2006) 108 (11): 1803.

https://doi.org/10.1182/blood.V108.11.1803.1803

Published: 2006

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Blood coagulation factor IX: structural insights impacting hemophilia B therapy

Rebalancing Hemostasis in Hemophilia: Interplay between Antithrombin and Ancillary Thrombin Inhibitors

Low Normal Levels of Factor V Enhance Thrombin Generation in Hemophilia a in a Tissue Factor Pathway Inhibitor Independent Manner

Hypertonicity and/or Acidosis Induce Marked Rheological Changes Under Hypoxic Conditions in Sickle Trait Red Blood Cells

Red blood cell microvesicles activate the contact system, leading to factor IX activation via 2 independent pathways

Abnormal joint and bone wound healing in hemophilia mice is improved by extending factor IX activity after hemarthrosis

In vitro activation of coagulation by human neutrophil DNA and histone proteins but not neutrophil extracellular traps

Adding some muscle to blood coagulation

The Effect of Prophylactic Recombinant Factor IX and Glycopegylated Factor IX to Normalize Articular Wound Healing Following Hemarthrosis Examined in Hemophilia B Mice

Purified DNA, but Not Neutrophil Extracellular Traps (NETs), Promotes Contact Activation of Coagulation

Polyphosphates rock! A role in thrombosis?

Differential contribution of FXa and thrombin to vascular inflammation in a mouse model of sickle cell disease

Partial Reversal of Dabigatran Effect by a Prothrombin Complex Concentrate in a Model of Thrombin Generation

Factor VIIa: on its own and loving it

The Impact of Factor IX Level on Thrombin Generation and Bleeding During Warfarin Anticoagulation

Increased Platelet Binding of NN1731, a Factor VIIa Variant with Enhanced Tissue Factor-Independent Activity.

Celecoxib Does Not Delay Cutaneous Wound Healing in Hemophilia B Mice.

Perivascular tissue factor is down-regulated following cutaneous wounding: implications for bleeding in hemophilia

Restoring Initial Thrombin Generation Does Not Normalize Cutaneous Wound Healing in Hemophilia B.

Tissue Factor Is Absent from Sites of Cutaneous Wounds: Implications for Bleeding in Hemophilia.

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American Society of Hematology

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