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Mutagenic DNA Lesions in Normal Hematopoietic Stem Cells Persist for Years Causing Distinct Patterns of Mutation

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Michael Spencer Chapman, Emily Mitchell, Kenichi Yoshida, Nicholas Williams, Margarete A. Fabre, Anna Maria Ranzoni, Philip S. Robinson, Lori Kregar, C. Matthias Wilk, Steffen Boettcher, Krishnaa Mahbubani, Kourosh Saeb-Parsy, Stanley Ng, George S Vassiliou, Kate Gowers, Sam Janes, Matt Hoare, Anthony R Green, Ana Cvejic, Markus G. Manz, Elisa Laurenti, Inigo Martincorena, Michael Stratton, Jyoti Nangalia, Tim H.H. Coorens, Peter Campbell
Journal: Blood
Blood (2024) 144 (Supplement 1): 2673.
https://doi.org/10.1182/blood-2024-208773
Published: 2024