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Journal Articles

Clone-specific epigenetic regulatory mechanisms in ASXL1-mutant chronic myelomonocytic leukemia

Moritz Binder, Terra Lasho, Jenna Fernandez, Wazim Mohammed Ismail, Amelia Mazzone, Christy Finke, Pankaj Pradeep, Abhishek Mangaonkar, Nickolas Steinauer, Huihuang Yan, Liguo Wang, Alexandre Gaspar-Maia, Mrinal Patnaik

Blood (2025) 146 (Supplement 1): 234.

https://doi.org/10.1182/blood-2025-234

Published: 2025

Journal Articles

Prevalence, clinical correlates and clonal inferences of concurrent splicing factor mutations in patients with myeloid neoplasms

Nickolas Steinauer, Vihan Singh, Terra Lasho, Christy Finke, Alejandro Ferrer, Pankaj Pradeep, Jenna Fernandez, Clifford Csizmar, Aref Al-Kali, David Viswanatha, Rong He, Abhishek Mangaonkar, Xi Zhang, Mrinal Patnaik

Blood (2025) 146 (Supplement 1): 5650.

https://doi.org/10.1182/blood-2025-5650

Published: 2025

Journal Articles

Spatial multiomics reveal a critical role for TIM4-expressing macrophages in blast transformation of chronic myelomonocytic leukemia

Abhishek Mangaonkar, Justin Boysen, Terra Lasho, Christy Finke, Jenna Fernandez, Jose Villasboas Bisneto, Mehrdad Hefazi Torghabeh, Pankaj Pradeep, Will Sherman, Christy Trussoni, Tamas Ordog, Maha Rahim, Alejandro Ferrer, Kaaren Reichard, Mrinal Patnaik

Blood (2025) 146 (Supplement 1): 3831.

https://doi.org/10.1182/blood-2025-3831

Published: 2025

Journal Articles

Somatic ASXL1 mutations in chronic myelomonocytic leukemia result in loss of imprinting control and overexpression of DLK1 through deregulation of DNA methylation

Pankaj Pradeep, Jenna Fernandez, Abhishek Mangaonkar, Nickolas Steinauer, Moritz Binder, Huihuang Yan, Christy Finke, Zhifu Sun, Terra Lasho, Mrinal Patnaik

Blood (2025) 146 (Supplement 1): 1457.

https://doi.org/10.1182/blood-2025-1457

Published: 2025

Journal Articles

Unique NK-like T cell population identified in UBA1mt cells in vexas associated with IL-8 mediated activity and cytotoxic response pathways

Terra Lasho, Jenna Fernandez, Pankaj Pradeep, Christy Finke, Abhishek Mangaonkar, Nickolas Steinauer, Bhavisha Patel, Neal Young, David Beck, Kenneth Warrington, Matthew J Koster, Yael Kusne, Fernanda Guitterez-Rodrigues, Mrinal Patnaik

Blood (2025) 146 (Supplement 1): 1428.

https://doi.org/10.1182/blood-2025-1428

Published: 2025

Journal Articles

Rapid hematologic germline testing using hair follicle-derived DNA for germline predisposition and inherited marrow failure states

Emma St. Martin, Abhishek Mangaonkar, Ann Moyer, Juliana Perez Botero, Alejandro Ferrer, Ross Rowsey, Benjamin Kipp, Dong Chen, Talha Badar, Jenna Fernandez, Yael Kusne, Christy Finke, Jodi Rindflesch, Terra Lasho, Mrinal Patnaik

Blood (2025) 146 (Supplement 1): 3211.

https://doi.org/10.1182/blood-2025-3211

Published: 2025

Journal Articles

LS1781 (Arm E): Phase II clinical trial to assess the safety and efficacy of high dose IV ascorbic acid with decitabine in newly diagnosed TET2 mutant chronic myelomonocytic leukemia (CMML)

Abhishek Mangaonkar, Jenna Fernandez, Ashya Burgess, Kristen McCullough, Christy Finke, Terra Lasho, Michelle Amundson, Antoine Saliba, Aasiya Matin, Aref Al-Kali, Hassan Alkhateeb, Mithun Shah, Betsy Knopf, Thomas Witzig, Mrinal Patnaik

Blood (2025) 146 (Supplement 1): 2079.

https://doi.org/10.1182/blood-2025-2079

Published: 2025

Journal Articles

Fetal hemoglobin dysregulation in inherited and acquired bone marrow failure syndromes

Blood (2025) 146 (Supplement 1): 6750.

https://doi.org/10.1182/blood-2025-6750

Published: 2025

Journal Articles

MC210807: Phase 1 clinical trial assessing the safety and efficacy of onvansertib, a novel, oral, PLK1 inhibitor in Relapsed/Refractory myeloproliferative chronic myelomonocytic leukemia (CMML).

Abhishek Mangaonkar, Kristen McCullough, Susan Geyer, Ashya Burgess, Kimberly Rice, Eric Asmus, Patricia Koenig, Terra Lasho, Christy Finke, Rachel Reither, Ryan Carr, Jenna Fernandez, Antoine Saliba, Aref Al-Kali, Martin Fernandez-Zapico, Mrinal Patnaik

Blood (2025) 146 (Supplement 1): 5634.

https://doi.org/10.1182/blood-2025-5634

Published: 2025

Journal Articles

Interplay between mutant DNMT3A and UBA1 worsens survival through altered inflammatory and metabolic pathways

Blood (2025) 146 (Supplement 1): 3191.

https://doi.org/10.1182/blood-2025-3191

Published: 2025

Journal Articles

High-dose IV ascorbic acid therapy for patients with CCUS with TET2 mutations

Zhuoer Xie, Jenna Fernandez, Terra Lasho, Christy Finke, Michelle Amundson, Kristen B. McCullough, Betsy R. LaPlant, Abhishek A. Mangaonkar, Naseema Gangat, Kaaren K. Reichard, Michelle Elliott, Thomas E. Witzig, Mrinal M. Patnaik

Blood (2024) 144 (23): 2456–2461.

https://doi.org/10.1182/blood.2024024962

Published: 2024

Includes: Supplemental data

Journal Articles

Spectrum of clonal hematopoiesis in VEXAS syndrome

Blood (2023) 142 (3): 244–259.

https://doi.org/10.1182/blood.2022018774

Published: 2023

Includes: Supplemental data

Journal Articles

Clonal Compositions Involving Epigenetic Regulator Gene Mutations in Clonal Hematopoiesis, Clonal Cytopenias of Undetermined Significance and Chronic Myelomonocytic Leukemia

Blood (2021) 138 (Supplement 1): 2592.

https://doi.org/10.1182/blood-2021-146849

Published: 2021

Journal Articles

Clonal Hematopoiesis of Indeterminate Potential Is Associated with Increased Age-Independent Morbidity and Mortality in Patients with COVID-19- the Beyond DNA COVID-19 Project

Marissa Li, Terra Lasho, Moritz Binder, Wazim Mohammed Ismail, Susan M. Geyer, Jenna Fernandez, Yael Kusne, Abhishek A. Mangaonkar, Minsuk Kim, Alexandre Gaspar Maia, Nicholas Chia, Mrinal M. Patnaik

Blood (2021) 138 (Supplement 1): 2164.

https://doi.org/10.1182/blood-2021-151548

Published: 2021

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Clone-specific epigenetic regulatory mechanisms in ASXL1-mutant chronic myelomonocytic leukemia

Prevalence, clinical correlates and clonal inferences of concurrent splicing factor mutations in patients with myeloid neoplasms

Spatial multiomics reveal a critical role for TIM4-expressing macrophages in blast transformation of chronic myelomonocytic leukemia

Somatic ASXL1 mutations in chronic myelomonocytic leukemia result in loss of imprinting control and overexpression of DLK1 through deregulation of DNA methylation

Unique NK-like T cell population identified in UBA1mt cells in vexas associated with IL-8 mediated activity and cytotoxic response pathways

Rapid hematologic germline testing using hair follicle-derived DNA for germline predisposition and inherited marrow failure states

LS1781 (Arm E): Phase II clinical trial to assess the safety and efficacy of high dose IV ascorbic acid with decitabine in newly diagnosed TET2 mutant chronic myelomonocytic leukemia (CMML)

Fetal hemoglobin dysregulation in inherited and acquired bone marrow failure syndromes

MC210807: Phase 1 clinical trial assessing the safety and efficacy of onvansertib, a novel, oral, PLK1 inhibitor in Relapsed/Refractory myeloproliferative chronic myelomonocytic leukemia (CMML).

Interplay between mutant DNMT3A and UBA1 worsens survival through altered inflammatory and metabolic pathways

High-dose IV ascorbic acid therapy for patients with CCUS with TET2 mutations

Spectrum of clonal hematopoiesis in VEXAS syndrome

Clonal Compositions Involving Epigenetic Regulator Gene Mutations in Clonal Hematopoiesis, Clonal Cytopenias of Undetermined Significance and Chronic Myelomonocytic Leukemia

Clonal Hematopoiesis of Indeterminate Potential Is Associated with Increased Age-Independent Morbidity and Mortality in Patients with COVID-19- the Beyond DNA COVID-19 Project

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American Society of Hematology

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American Society of Hematology

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