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Ioanna Xagoraris
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Journal Articles

SAMHD1 dependence of cgas-sting-associated anti-tumor immune responses in classical Hodgkin lymphoma

Free
Ioanna Xagoraris, Eleni Psaroudaki, Dora Trogrlic, Ying Yang, Andreas Lundqvist, Georgios Rassidakis
Journal: Blood
Blood (2025) 146 (Supplement 1): 1782.
https://doi.org/10.1182/blood-2025-1782
Published: 2025
Journal Articles

The immunomodulatory effects of IRF3/7 transcription factors and IL10 in ALK+ anaplastic large cell lymphoma (ALCL)

Free
Georgios Rassidakis, Dora Trogrlic, Ying Yang, Alma Mansson, Hong Qian, Andreas Lundqvist, Vasiliki Leventaki, Ioanna Xagoraris
Journal: Blood
Blood (2025) 146 (Supplement 1): 5336.
https://doi.org/10.1182/blood-2025-5336
Published: 2025
Journal Articles

NPM-ALK Oncoprotein Suppresses Anti-Tumor Immune Responses Partially through Cgas-Sting Pathway in ALK+ Anaplastic Large Cell Lymphoma

Free
Ioanna Xagoraris, Ying Yang, Dora Trogrlic, Alma Mansson, Christina Plastira, Vasiliki Leventaki, Hong Qian, Andreas Lundqvist, George Z. Rassidakis
Journal: Blood
Blood (2024) 144 (Supplement 1): 2999.
https://doi.org/10.1182/blood-2024-205772
Published: 2024
Journal Articles

Modulation of the CGAS-Sting Anti-Tumor Immune Response Pathway in an NF-KB-Dependent or -Independent Manner As a Potential Therapeutic Target in Classical Hodgkin Lymphoma (cHL)

Free
Ioanna Xagoraris, Konstantina Stathopoulou, Persa Xyderou, Marzia Palma, Elias Drakos, Theodoros P. Vassilakopoulos, George Z. Rassidakis
Journal: Blood
Blood (2022) 140 (Supplement 1): 3579–3580.
https://doi.org/10.1182/blood-2022-164497
Published: 2022
Journal Articles

The NPM-ALK Oncogenic Kinase Suppresses CGAS-Sting-Associated Anti-Tumor Immune Responses through STAT3 Activation in Anaplastic Large Cell Lymphoma (ALCL)

Free
Ioanna Xagoraris, Georgia Kokaraki, Christina Plastira, Konstantina Stathopoulou, Vasiliki Leventaki, Elias Drakos, Jeffrey Medeiros, Anders Österborg, George Z. Rassidakis
Journal: Blood
Blood (2021) 138 (Supplement 1): 1338.
https://doi.org/10.1182/blood-2021-149257
Published: 2021
Journal Articles

Mutations of the Novel Tumor Suppressor Gene SAMHD1 Are Frequent and Correlate with Decreased Protein Expression in Peripheral T-Cell Lymphomas (PTCL)

Free
Georgia Kokaraki, Ioanna Xagoraris, Pedro Farrajota Neves Da Silva, Lesley Ann Sutton, Raul Maia Falcão, Jorge Estefano Santana de Souza, Anders Österborg, Valtteri Wirta, Richard Rosenquist Brandell, Georgios Z. Rassidakis
Journal: Blood
Blood (2021) 138 (Supplement 1): 3515.
https://doi.org/10.1182/blood-2021-147428
Published: 2021
Journal Articles

SAMHD1 Is Variably Expressed in Mantle Cell Lymphoma and Correlated to SOX11 but Not to Survival

Free
Agata Magdalena Wasik, PhD MSc, Elin Marin, MD, Magali Merrien, MSc, Joana de Matos Rodrigues, PhDstudent, Martin Lord, PhD, Ioanna Xagoraris, MD, Birger Christensson, MD PhD, George Rassidakis, MD PhD, Mats Jerkeman, Sara Ek, PhD, Birgitta Sander, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4136.
https://doi.org/10.1182/blood-2018-99-118087
Published: 2018
Journal Articles

The Novel Tumor Suppressor SAMHD1 Is Differentially Expressed and Partly Regulated By MYC in Peripheral T-Cell Lymphomas (PTCL)

Free
Pedro Farrajota Neves Da Silva, MD, Nikolaos Tsesmetzis, Ioanna Xagoraris, MD, Agata Magdalena Wasik, PhD MSc, Georgia Kokaraki, PhD, Evangelos Tzoras, Anders Österborg, MD PhD Prof., Birgitta Sander, MD PhD, Nikolas Herold, MD PhD, George Rassidakis, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4130.
https://doi.org/10.1182/blood-2018-99-119229
Published: 2018
Journal Articles

MAPKAP1 (Sin1), a Key Component of the MTORC2 Complex, Confers Resistance to Sorafenib and Correlates with Adverse Clinical Outcomes in Acute Myeloid Leukemia

Free
Joseph David Khoury, MD, Ioanna Xagoraris, MD, Nikolaos Tsesmetzis, MSc., Ida Hed Hed Myrberg, PhD, Thale Kristin Olsen, Siok Bian Ng, Wee-Joo Chng, MBBS, PhD FRCPath, FRCP, Benedict Yan, Chin Hin Ng, MD MRCP, Michael Andreeff, MD PhD, L. Jeffrey Medeiros, MD, Hagop M. Kantarjian, MD, Herold Nikolas, MD PhD, Dan Grander, MD PhD, George Rassidakis, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3964.
https://doi.org/10.1182/blood.V130.Suppl_1.3964.3964
Published: 2017
Journal Articles

Low-Level SAMHD1 Expression in Acute Myeloid Leukemia Blasts Correlates with Favorable Outcome in Patients with Diploid Cytogenetics Treated with Cytarabine-Based Chemotherapy Regimens

Free
George Rassidakis, MD PhD, Herold Nikolas, MD PhD, Ida Hed Hed Myrberg, PhD, Nikolaos Tsesmetzis, MSc., Dan Grander, MD PhD, Hagop M. Kantarjian, MD, L. Jeffrey Medeiros, MD, Ioanna Xagoraris, MD, Joseph David Khoury, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3928.
https://doi.org/10.1182/blood.V130.Suppl_1.3928.3928
Published: 2017
Journal Articles

Downregulation of the Tumor Suppressor SAMHD1 in Classical Hodgkin Lymphoma

Free
Ioanna Xagoraris, MD, Theodoros Vassilakopoulos, MDPhD, Nikolas Herold, MDPhD, Nikolaos Tsesmetzis, MSc., Elias Drakos, MD PhD, Joseph David Khoury, MD, George Rassidakis, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1480.
https://doi.org/10.1182/blood.V130.Suppl_1.1480.1480
Published: 2017