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Gregory M Chen
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Journal Articles

STAT1-mediated interferon signatures are associated with preclinical JAK inhibitor sensitivity in T-ALL

Available to Purchase
Clinical Trials & Observations
Jason Xu, Jonathan H. Sussman, Austin Yang, Satoshi Yoshimura, Jianzhong Hu, Changya Chen, Tiffaney Vincent, Shovik Bandyopadhyay, Elizabeth Y. Li, Tristan Lim, Omar Elghawy, Adam Barsouk, Damjan Karanfilovski, Shira L. Wald, Gregory M. Chen, David Wu, Haley Newman, Alexander Li, Yusha Sun, Chia-Hui Chen, Kathrin Bernt, Brent L. Wood, Stuart S. Winter, Kimberly P. Dunsmore, Elizabeth Raetz, Meenakshi Devidas, Stanley Pounds, Mignon Loh, Stephen P. Hunger, Mark Y. Chiang, Caroline Diorio, Danika Di Giacomo, Petri Pölönen, Charles G. Mullighan, Jun J. Yang, Kai Tan, David T. Teachey
Journal: Blood
Blood (2025) 145 (23): 2793–2798.
https://doi.org/10.1182/blood.2025028566
Published: 2025
Includes: Supplemental data
Journal Articles

In Vivo Persistence and Function of CAR19 T-Cell Products for Pediatric B-Cell Acute Lymphoblastic Leukemia Are Impacted By Media, Cytokine Supplementation and Metabolite Bioavailability during Ex Vivo Manufacturing

Free
Caitlin R. Hopkins, Amanda M. DiNofia, Shannon L. Maude, Gregory M. Chen, Kwame Attah M. Boateng-Antwi, Jessica Perazzelli, Andres F. Mendez Corea, Alexander Shestov, Mercy Gohil, Yimei Li, Wei-Ting Hwang, Bakir Valentić, Shannon Christensen, Julie Jadlowsky, Regina M. Myers, Caroline Diorio, Megan M. Davis, Theresa Colligon, Gabriela Plesa, Don L. Siegel, Bruce Levine, Carl H. June, Roddy S. O'Connor, Stephan A. Grupp, Joseph A. Fraietta
Journal: Blood
Blood (2024) 144 (Supplement 1): 3473.
https://doi.org/10.1182/blood-2024-210324
Published: 2024
Journal Articles

Interferon-Activated Gene Signatures Associate with Chemotherapy Resistance and Sensitivity to JAK-Inhibition in Refractory ETP-ALL

Free
Jason Xu, Jonathan Sussman, Austin Yang, Satoshi Yoshimura, Changya Chen, Omar Elghawy, Tiffaney Vincent, Caroline Diorio, Shovik Bandyopadyay, Jianzhong Hu, Alexander Lai Li, Gregory M. Chen, Chia-Hui Chen, Rawan Shraim, Haley Newman, Yang Ding, Elizabeth Li, Wenbao Yu, Anusha Thadi, Kyung Jin Ahn, Petri Pölönen, Abdelrahman Elsayed, David Frank, Elizabeth A. Raetz, Mignon L. Loh, Brent L. Wood, Stuart S. Winter, Kimberly P. Dunsmore, Meenakshi Devidas, Chunxu Qu, Stanley Pounds, Stephen P. Hunger, Charles G. Mullighan, Jun J. Yang, Kai Tan, David T. Teachey
Journal: Blood
Blood (2024) 144 (Supplement 1): 1464.
https://doi.org/10.1182/blood-2024-211090
Published: 2024
Journal Articles

Decade-Long Remissions of Leukemia Sustained By the Persistence of Activated CD4+ CAR T-Cells

Free
J. Joseph Melenhorst, Gregory M Chen, Meng Wang, David L. Porter, Peng Gao, Shovik Bandyopadhyay, Iulian Pruteanu-Malinici, Christopher L Nobles, Sayantan Maji, Noelle V Frey, Saar Gill, Lifeng Tian, Irina Kulikovskaya, Megan M Davis, Joseph A Fraietta, Jennifer L Brogdon, Regina Young, David E Ambrose, Anne Chew, Bruce L Levine, Don L. Siegel, Cécile Alanio, E. John Wherry, Frederic D. Bushman, Simon F Lacey, Kai Tan, Carl H June
Journal: Blood
Blood (2021) 138 (Supplement 1): 166.
https://doi.org/10.1182/blood-2021-152664
Published: 2021