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Cristiana O'Brien
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Journal Articles

Plasma lipid levels predict chemotherapy response and survival in acute myeloid leukemia

Open Access
Cristiana O'Brien, Nirvana Nursimulu, Anit Tyagi, Rachel Culp-Hill, Andrea Arruda, Tracy Murphy, Mark D Minden, Andrew Kent, Brett M. Stevens, Daniel A. Pollyea, Kristin Hope, Sushant Kumar, Julie A. Reisz, Angelo D'Alessandro, Courtney L Jones
Journal: Blood
Blood blood.2025029132.
https://doi.org/10.1182/blood.2025029132
Published: 2025
Includes: Supplemental data
Journal Articles

Examining the Clinical Relevance of the AML Plasma Metabolome

Free
Cristiana O'Brien, Nirvana Nursimulu, Rachel Culp-Hill, Julie A Reisz Haines, Andrea Arruda, Mark D. Minden, Angelo D'Alessandro, Sushant Kumar, Kristin J. Hope, Courtney Jones
Journal: Blood
Blood (2024) 144 (Supplement 1): 2937.
https://doi.org/10.1182/blood-2024-203960
Published: 2024
Journal Articles

Polyamines Are Required for AML LSC Function through Their Role in Regulating eIF5A Dependent Protein Synthesis

Free
Vincent Rondeau, Rachel Culp-Hill, Julie A Reisz, Duhan Yendi, Aarushi Gupta, Jacob Berman, Cristiana O'Brien, Tianyi Ling, Aleksandra Bourdine, Mary Shi, Jonathan St-Germain, Soheil Jahangiri, Anastasia N. Tikhonova, Andrea Arruda, Mark D. Minden, Brian Raught, Angelo D'Alessandro, Courtney L Jones
Journal: Blood
Blood (2023) 142 (Supplement 1): 585.
https://doi.org/10.1182/blood-2023-187283
Published: 2023
Journal Articles

Simultaneous Inhibition of SIRT3 and Cholesterol Homeostasis Targets AML Stem Cells By Perturbing Fatty Acid β-Oxidation and Inducing Lipotoxicity

Free
Cristiana O'Brien, Tianyi Ling, Jacob Berman, Rachel Culp-Hill, Julie A. Reisz, Vincent Rondeau, Soheil Jahangiri, Jonathan St-Germain, Vinitha Macwan, Audrey Astori, Andy G.X. Zeng, Jun Young Hong, Meng Li, Min Yang, Sadhan Jana, John E. Dick, Hening Lin, Ari Melnick, Anastasia N Tikhonova, Andrea Arruda, Mark D. Minden, Brian Raught, Angelo D'Alessandro, Courtney L Jones
Journal: Blood
Blood (2022) 140 (Supplement 1): 104–106.
https://doi.org/10.1182/blood-2022-157794
Published: 2022
Journal Articles

Sirtuin 3 Inhibition Targets AML Stem Cells through Perturbation of Fatty Acid Oxidation

Free
Cristiana O'Brien, Jacob Berman, Rachel Culp-Hill, Julie Reisz, Tianyi Ling, Vincent Rondeau, Meng Li, Min Yang, Jun Young Hong, Hening Lin, Ari Melnick, Andrea Arruda, Mark D. Minden, Angelo D'Alessandro, Courtney L Jones
Journal: Blood
Blood (2021) 138 (Supplement 1): 2240.
https://doi.org/10.1182/blood-2021-148143
Published: 2021