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Christopher R Flowers
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Journal Articles

Blunted CD40-responsive enhancer activation in CREBBP-mutant lymphomas can be restored by enforced CD4 T-cell engagement

Open Access
Haopeng Yang, Wenchao Zhang, Vida Ravanmehr, Guiling Cui, Kevin Bowman, Ruidong Chen, Jared Henderson, Shyanne Ruby Lockman, Estela Rojas, Ashley Lauren Wilson, Sydney Parsons, Ariel Mechaly, Leslie Regad, Ahmed Haouz, Christopher R. Flowers, Sattva S. Neelapu, Loretta J. Nastoupil, Richard Eric Davis, Qing Deng, Fernando Rodrigues Lima, Michael R Green
Journal: Blood
Blood blood.2024026664.
https://doi.org/10.1182/blood.2024026664
Published: 2025
Includes: Supplemental data
Journal Articles

End points and Outcomes in Follicular Lymphoma: What should we measure, how, and why?

Available to Purchase
Clinical Trials & Observations
Mengyang Di, Matthew J. Maurer, Christopher R. Flowers
Journal: Blood
Blood blood.2024026978.
https://doi.org/10.1182/blood.2024026978
Published: 2025
Journal Articles

Antibiotic-induced loss of gut microbiome metabolic output correlates with clinical responses to CAR T-cell therapy

Available to Purchase
Clinical Trials & Observations
Rishika Prasad, Abdur Rehman, Lubna Rehman, Faezeh Darbaniyan, Viktoria Blumenberg, Maria-Luisa Schubert, Uria Mor, Eli Zamir, Sabine Schmidt, Tomo Hayase, Chia-Chi Chang, Lauren McDaniel, Ivonne Flores, Paolo Strati, Ranjit Nair, Dai Chihara, Luis E. Fayad, Sairah Ahmed, Swaminathan P. Iyer, Michael Wang, Preetesh Jain, Loretta J. Nastoupil, Jason Westin, Reetakshi Arora, Joel Turner, Fareed Khawaja, Ranran Wu, Jennifer B. Dennison, Meghan Menges, Melanie Hidalgo-Vargas, Kayla Reid, Marco L. Davila, Peter Dreger, Felix Korell, Anita Schmitt, Mark R. Tanner, Richard E. Champlin, Christopher R. Flowers, Elizabeth J. Shpall, Samir Hanash, Sattva S. Neelapu, Michael Schmitt, Marion Subklewe, Johannes Francois-Fahrmann, C. K. Stein-Thoeringer, Eran Elinav, Michael D. Jain, Eiko Hayase, Robert R. Jenq, Neeraj Y. Saini
Journal: Blood
Blood (2025) 145 (8): 823–839.
https://doi.org/10.1182/blood.2024025366
Published: 2025
Includes: Supplemental data
Journal Articles

Real-world impact of differences in the WHO and ICC classifications of non-Hodgkin lymphoma: a LEO cohort study analysis

Available to Purchase
Brooj Abro, Matthew J. Maurer, Thomas M. Habermann, W. Richard Burack, Jennifer R. Chapman, Jonathon B. Cohen, Jonathan W. Friedberg, Giorgio Inghirami, Brad S. Kahl, Melissa C. Larson, Brian K. Link, Izidore S. Lossos, Peter Martin, Timothy J. McDonnell, Loretta J. Nastoupil, Shaun M. Riska, Sergei Syrbu, Francisco Vega, Kiran R. Vij, Christopher R. Flowers, James R. Cerhan, David L. Jaye, Andrew L. Feldman
Journal: Blood
Blood (2024) 144 (19): 2063–2066.
https://doi.org/10.1182/blood.2024025681
Published: 2024
Includes: Supplemental data
Journal Articles

Comprehensive Characterization and Validation of the Tumor Microenvironment in Patients with Relapsed/Refractory Large B-Cell Lymphoma Identifies Subgroups with Greatest Benefit from CD19 CAR T-Cell Therapy

Free
Xubin Li, Kartik Singhal, Qing Deng, Dai Chihara, David A Russler-Germain, Usama Hussein, Jennifer Ann Foltz, Jared Henderson, Ashley Wilson, Evelyn Schmidt, Imran A. Nizamuddin, Tommy Dinh, Ryan Sun, Akhil Kesaraju, Laura K. Hilton, David W. Scott, Francisco Vega, Christopher R. Flowers, Obi Griffith, Todd A Fehniger, Malachi Griffith, Michael R. Green
Journal: Blood
Blood (2024) 144 (Supplement 1): 643.
https://doi.org/10.1182/blood-2024-204166
Published: 2024
Journal Articles

Survival Outcomes and Genetic Assessment in Patients with Dual Diagnoses of B-Cell and T-Cell Lymphomas

Free
Anath Lionel, Karmila Murphy, Amy A. Ayers, Christopher R. Flowers, Keyur P. Patel, Courtney D. DiNardo, Francisco Vega, Dai Chihara
Journal: Blood
Blood (2024) 144 (Supplement 1): 1680.
https://doi.org/10.1182/blood-2024-211432
Published: 2024
Journal Articles

Large Cell Transformation in Mycosis Fungoides & Sezary Syndrome: An Analysis of 445 Cases

Free
Rishabh Lohray, Lei Feng, Auris O Huen, Iyanuoluwa Ogundipe, Luis Malpica, Bouthaina S. Dabaja, Julia Dai, Jillian R. Gunther, Chitra Hosing, Roberto N. Miranda, L. Jeffrey Medeiros, Samer A. Srour, Jeremy Ramdial, Francisco Vega, Mansoor Noorani, Amy A. Ayers, Penny Q. Fang, Luis E. Fayad, Chelsea C. Pinnix, Madeleine Duvic, Jie Xu, Christopher R. Flowers, Susan Y. Wu, Kunhwa Kim, Carlos P Torres-Cabala, Swaminathan P Iyer, Ranjit Nair
Journal: Blood
Blood (2024) 144 (Supplement 1): 1679.
https://doi.org/10.1182/blood-2024-209213
Published: 2024
Journal Articles

Five-Year Analysis of the POLARIX Study: Prolonged Follow-up Confirms Positive Impact of Polatuzumab Vedotin Plus Rituximab, Cyclophosphamide, Doxorubicin, and Prednisone (Pola-R-CHP) on Outcomes

Free
Gilles Salles, Franck Morschhauser, Laurie H. Sehn, Alex F. Herrera, Jonathan W. Friedberg, Marek Trněný, Georg Lenz, Jeff P. Sharman, Charles Herbaux, John M. Burke, Matthew Matasar, Graham P. Collins, Yuqin Song, Antonio Pinto, Shinya Rai, Koji Izutsu, Calvin Lee, Saibah Chohan, Matthew Sugidono, Yanwen Jiang, Connie Lee Batlevi, Mark Yan, Jamie Hirata, Hervé Tilly, Christopher R. Flowers
Journal: Blood
Blood (2024) 144 (Supplement 1): 469.
https://doi.org/10.1182/blood-2024-197938
Published: 2024
Journal Articles

Vulnerable Elders Survey (VES-13) and Longitudinal Analysis of Quality of Life in Indolent Non-Hodgkin Lymphoma: A Multi-Institutional Prospective Cohort Study

Free
Mazie Tsang, Brie N Noble, Carla Casulo, Carrie A Thompson, Allison C. Rosenthal, Dai Chihara, Eric Mou, Urshila Durani, Annalynn M Williams, Michelle A.T. Hildebrandt, Kathleen J Yost, Melissa C. Larson, Brianna Gysbers, Matthew J. Maurer, Andrew L. Feldman, David L. Jaye, Jon Tilburt, Ajay Major, Talal Hilal, Yucai Wang, Amber Koehler, Timothy G. Call, Sameer A. Parikh, Javier L. Munoz, Gita Thanarajasingam, Loretta Nastoupil, Grzegorz S. Nowakowski, Jonathon B. Cohen, Thomas M. Habermann, Christopher Strouse, Izidore S. Lossos, Brad S. Kahl, Peter Martin, Christopher R. Flowers, James R. Cerhan, Amylou C Dueck
Journal: Blood
Blood (2024) 144 (Supplement 1): 2345.
https://doi.org/10.1182/blood-2024-210594
Published: 2024
Journal Articles

Radiation Therapy and Monocyte Activation in Large B-Cell Lymphoma Patients Treated with CAR T-Cell Therapy

Free
Penny Q. Fang, Susan Y. Wu, Jillian R. Gunther, Alena Frank, Pavel Zemskiy, Aleksandr Zaitsev, Evgenii S Bolshakov, Anastasiya Terenteva, Krystle Nomie, Michelly Abreu, Karla Ow, Minifrida Santiago, Jaimole Varghese, Amy Ayers, Jared Henderson, Sairah Ahmed, Jason R. Westin, Christopher R. Flowers, Sattva S. Neelapu, Bouthaina S. Dabaja, Chelsea C. Pinnix, Paolo Strati
Journal: Blood
Blood (2024) 144 (Supplement 1): 4377.
https://doi.org/10.1182/blood-2024-203844
Published: 2024
Journal Articles

Treatment Patterns and Real World Outcomes with Clinical Trials for Patients with Follicular Lymphoma across Lines of Therapy

Free
Neha Akkad, Amy Ayers, Kumudha Balakrishnan, Loretta Nastoupil, Dai Chihara, Luis Malpica, Paolo Strati, Ziyi Li, Christopher R. Flowers
Journal: Blood
Blood (2024) 144 (Supplement 1): 4396.
https://doi.org/10.1182/blood-2024-201804
Published: 2024
Journal Articles

Clinical Outcomes and Patterns of Care Among Patients with Newly Diagnosed Hodgkin Lymphoma in a Safety-Net Health System

Free
Jun Yang Jiang, Trung Minh Nguyen, Jason Lu, Danielle Guffey, Rockbum Kim, Abiodun Oluyomi, Omar Rosales, Raka Bandyo, Courtney Nicole Miller-Chism, Mark M. Udden, Martha P. Mims, Tareq Abuasab, Akiva Diamond, Purnima Sravanti Teegavarapu, Chijioke Nze, Christopher R. Flowers, Ang Li
Journal: Blood
Blood (2024) 144 (Supplement 1): 3727.
https://doi.org/10.1182/blood-2024-203368
Published: 2024
Journal Articles

Peripheral Blood CAR T-Cell Level Using a Clia-Validated Assay Is Prognostic for Treatment Response and Icans in Large B-Cell Lymphoma

Free
Anath Lionel, Naishu Kui, Ryan Sun, Eslam Aboismail, Sanjit Om Tewari, Ajlan Al Zaki, Sushanth Gouni, Preetesh Jain, Dai Chihara, Swaminathan P Iyer, Michael Wang, Ranjit Nair, Luis Enrique Malpica Castillo, Hun Ju Lee, Chijioke Nze, Luis E. Fayad, Frederick Hagemeister, Maria Alma Rodriguez, Amy A. Ayers, Cristina Gutierrez, Gabriela Rondon, Fareed Khawaja, Partow Kebriaei, Elizabeth J. Shpall, Christopher R. Flowers, Jason R. Westin, Paolo Strati, Wei WANG, Sa A. Wang, Sairah Ahmed, Sattva S. Neelapu
Journal: Blood
Blood (2024) 144 (Supplement 1): 3001.
https://doi.org/10.1182/blood-2024-208300
Published: 2024
Journal Articles

A Phase Ib, Open-Label Study of Add on Therapy with CK0804 in Participants with Myelofibrosis and Suboptimal Response to Ruxolitinib

Free
Lucia Masarova, Meixian Huang, Swati Goel, Sharon Bledsoe, Naveen Pemmaraju, Tapan M. Kadia, Prithviraj Bose, Jo Ishizawa, Guillermo Montalban-Bravo, Mi-Ae Lyu, Tara Sadeghi, Simrit Parmar, Christopher R. Flowers, Hagop M. Kantarjian
Journal: Blood
Blood (2024) 144 (Supplement 1): 999.
https://doi.org/10.1182/blood-2024-211587
Published: 2024
Journal Articles

Retreatment with R-CHOP-like Therapy Is Active with Durable Responses in Patients with Late Relapse of Diffuse Large B-Cell Lymphoma

Free
Eduardo Edelman Saul, Bryan Valcarcel, Amy A. Ayers, Mansoor Noorani, Dai Chihara, Fateeha Furqan, Sairah Ahmed, Swaminathan P Iyer, Sattva S. Neelapu, Luis E. Fayad, F. B. Hagemeister, Chijioke Nze, Preetesh Jain, Michael Wang, Paolo Strati, Ayushi Chauhan, Francisco Vega, Christopher R. Flowers, Jason R. Westin
Journal: Blood
Blood (2024) 144 (Supplement 1): 4454.
https://doi.org/10.1182/blood-2024-211247
Published: 2024
Journal Articles

Prospective Observational Cohort Study to Collect Granular Social Determinants of Health Data for Transplant and Cellular Therapy Candidates and Recipients

Free
Warren B Fingrut, KaNoisha Codrington, Ligny Hunter, Ricky Garcia, Charles Martinez, Gabriela Rondon, Denái R. Milton, Christopher R. Flowers, Elizabeth J. Shpall
Journal: Blood
Blood (2024) 144 (Supplement 1): 3573.1.
https://doi.org/10.1182/blood-2024-202666
Published: 2024
Journal Articles

Outcomes in Early Relapse of Follicular Lymphoma Versus Early Histologic Transformation Following Firstline Immunochemotherapy in Follicular Lymphoma

Free
Carla Casulo, Melissa C. Larson, Jonathan R Day, Urshila Durani, Mazie Tsang, Jonathan W. Friedberg, Grzegorz S. Nowakowski, Jean L. Koff, Dai Chihara, Richard Burack, Thomas M. Habermann, Loretta Nastoupil, Izidore S. Lossos, Peter Martin, Matthew Holets, Brad S. Kahl, Jonathan J. Cohen, James R. Cerhan, Christopher R. Flowers, Brian K. Link, Matthew J. Maurer
Journal: Blood
Blood (2024) 144 (Supplement 1): 1652.
https://doi.org/10.1182/blood-2024-201078
Published: 2024
Journal Articles

Real-World Predictors of Financial Toxicity in Patients with Lymphoma

Free
Syeda A Mina, Katherine E Smith, Ashley D Hickman, Melissa C. Larson, Brianna J Negaard, Brittany C Kimball, Matthew J. Maurer, Kathleen J Yost, Grzegorz S. Nowakowski, Izidore S. Lossos, Peter Martin, Jonathon B. Cohen, Brian K. Link, Brad S. Kahl, Loretta Nastoupil, James R. Cerhan, Christopher R. Flowers, Amylou C Dueck, Annalynn M Williams, Carla Casulo, Carrie A Thompson, Urshila Durani
Journal: Blood
Blood (2024) 144 (Supplement 1): 3754.
https://doi.org/10.1182/blood-2024-201896
Published: 2024
Journal Articles

Collective Analysis of Genomic Data Sets to Assess the Impact of Eligibility Criteria on Molecular Subsets in First-Line Clinical Trials for Patients with Diffuse Large B-Cell Lymphoma

Free
Robert Andrew Harkins, Dai Chihara, Christopher R. Flowers
Journal: Blood
Blood (2024) 144 (Supplement 1): 2970.
https://doi.org/10.1182/blood-2024-198813
Published: 2024
Journal Articles

Factors Influencing Clinical Trial Participation Among Patients with Non-Hodgkin Lymphoma Receiving Care in a Safety Net Hospital

Free
Alexis Romero, Sophia Nguyen, Amy A. Ayers, Rebecca Yzquierdo, Lorna McNeill, Hilary Ma, Michael Overman, James R. Cerhan, Christopher R. Flowers, Chijioke Nze
Journal: Blood
Blood (2024) 144 (Supplement 1): 3746.
https://doi.org/10.1182/blood-2024-211976
Published: 2024