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Safety and Preliminary Efficacy of F0002, an Anti-CD30 Antibody-Drug Conjugate, in Patients with Relapsed or Refractory Classical Hodgkin Lymphoma Previously Treated with Anti-PD-1 or PD-L1 Therapy: Results from F0002-101 Phase 1 Study

Free
Yuqin Song, Qingsong Yin, Zhiming Li, Jingye Meng, Yan Yan, Mengli Zhou, Wenyi Sun, Kezhen Liu, Jun Zhu
Journal: Blood
Blood (2024) 144 (Supplement 1): 1674.
https://doi.org/10.1182/blood-2024-193938
Published: 2024
Journal Articles

Five-Year Analysis of the POLARIX Study: Prolonged Follow-up Confirms Positive Impact of Polatuzumab Vedotin Plus Rituximab, Cyclophosphamide, Doxorubicin, and Prednisone (Pola-R-CHP) on Outcomes

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Gilles Salles, Franck Morschhauser, Laurie H. Sehn, Alex F. Herrera, Jonathan W. Friedberg, Marek Trněný, Georg Lenz, Jeff P. Sharman, Charles Herbaux, John M. Burke, Matthew Matasar, Graham P. Collins, Yuqin Song, Antonio Pinto, Shinya Rai, Koji Izutsu, Calvin Lee, Saibah Chohan, Matthew Sugidono, Yanwen Jiang, Connie Lee Batlevi, Mark Yan, Jamie Hirata, Hervé Tilly, Christopher R. Flowers
Journal: Blood
Blood (2024) 144 (Supplement 1): 469.
https://doi.org/10.1182/blood-2024-197938
Published: 2024
Journal Articles

CD93 + Myeloid Cells Suppress T-Cell-Mediated Anti-Tumor Immunity

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Hui Yu, Yixin Qian, Weiping Liu, Lan Mi, Yun Huang, Rui Peng, Jiaowu Cao, Dingyao Hu, Jun Zhu, Yuqin Song, Mi Deng
Journal: Blood
Blood (2024) 144 (Supplement 1): 960.
https://doi.org/10.1182/blood-2024-201309
Published: 2024
Journal Articles

Molecular Biology Study of Primary Immuno-Privileged Lymphomas

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Chen Zhang, Jili Deng, Lan Mi, Jiayue Qin, Lixia Liu, Yuqin Song
Journal: Blood
Blood (2024) 144 (Supplement 1): 4455.
https://doi.org/10.1182/blood-2024-212058
Published: 2024
Journal Articles

Prognosis Prediction and Treatment Recommendation for Follicular Lymphoma: Enhancing Decision-Making

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Xinze Li, Jiaxin Liu, Lan Mi, Liantao Ma, Junyi Gao, Yan Xie, Yuqin Song
Journal: Blood
Blood (2024) 144 (Supplement 1): 6353.
https://doi.org/10.1182/blood-2024-212407
Published: 2024
Journal Articles

Phase 1/2 Studies of DZD8586, a Non-Covalent BBB Penetrant LYN/BTK Dual Inhibitor, in BTK Inhibitor Resistant Chronic Lymphocytic Leukemia (CLL) and Other B-Cell Non-Hodgkin Lymphoma (B-NHL)

Free
Yuqin Song, Keshu Zhou, Hongmei Jing, Geoffrey Chong, Jianqiu Wu, Wei Liu, Zengjun Li, Ming Jiang, Mei Lan, Kaiyang Ding, Guohui CUI, Tingyu Wang, Xutao Guo, Sujun Gao, Constantine S. Tam, Haiyan Yang, Fang Zhu, Wei Yang, Jian-Qing Mi, Liping Su, Ke Fang, Ziyi Liu, Lindsey Roeker, Chan Y. Cheah, Jianyong Li, Lu-Gui Qiu
Journal: Blood
Blood (2024) 144 (Supplement 1): 3248.
https://doi.org/10.1182/blood-2024-197877
Published: 2024
Journal Articles

Efficacy and Safety of a New Regime Containing PD1 Antibody and Pegaspargase for Advanced-Stage or Relapsed/Refractory Natural Killer/T Cell Lymphoma

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Jie Chen, Linjun Zhao, Chongyang Wu, Haifeng Yu, Zhenling Li, Lihong Liu, Da Gao, Ying Sun, Xiaolei Wei, Yuanbin Wu, Yue Wang, Yuqin Song, Jun Zhu, Weiping Liu
Journal: Blood
Blood (2024) 144 (Supplement 1): 1686.
https://doi.org/10.1182/blood-2024-207412
Published: 2024
Journal Articles

High-Risk Subgroups and MRD: An Updated Analysis of the Phase 3 ECHO Trial of Acalabrutinib with Bendamustine/Rituximab in Previously Untreated Mantle Cell Lymphoma

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Martin Dreyling, Jiri Mayer, David Belada, Yuqin Song, Wojciech Jurczak, Jonas Paludo, Michael P. Chu, Iryna Kryachok, Laura Maria Fogliatto, Chan Y. Cheah, Marta Morawska, Juan-Manuel Sancho, Yufu Li, Caterina Patti, Cecily Forsyth, Jingyang Zhang, Robin Lesley, Safaa Ramadan, Simon Rule, Michael Wang
Journal: Blood
Blood (2024) 144 (Supplement 1): 1626.
https://doi.org/10.1182/blood-2024-200290
Published: 2024
Journal Articles

MBS303, a Novel 2:1 CD20×CD3 Bispecific Antibody, Demonstrated a Favorable Safety and Potent Antitumor Activity in Patients with Relapsed/Refractory (R/R) B-Cell Non-Hodgkin Lymphoma: Preliminary Results from a Phase Ⅰ, Dose-Escalation Trial

Free
Yuqin Song, Haiyan Yang, Youchao Jia, Lixia Sheng, Lijuan Deng, Xi Chen, Yongjing Tang, Xifang Liu, Sijun Liu, Min Wei, Feng Li
Journal: Blood
Blood (2024) 144 (Supplement 1): 6481.
https://doi.org/10.1182/blood-2024-199342
Published: 2024
Journal Articles

Linperlisib Combined with CHOP Regimen Followed By Autologous Hematopoietic Stem Cell Transplantation and Linperlisib Monotherapy Maintenance for Newly Diagnosed Nodal T-Follicular Helper Cell Lymphoma Patients: A Phase II Trial

Free
Weiping Liu, Yao Liu, Zengjun Li, Shujuan Wen, Zhihua Zhang, Liqun Zou, Ming Jiang, Liping Dou, Ou Bai, Jie Yu, Yue Wang, Jie Chen, Yuqin Song, Jun Zhu
Journal: Blood
Blood (2024) 144 (Supplement 1): 6389.
https://doi.org/10.1182/blood-2024-199929
Published: 2024
Journal Articles

Safety and Efficacy of Iruplinalkib for Patients with Relapsed or Refractory (r/r) ALK+ Lymphoma: A Phase II Trial

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Yue Wang, Fang Wei, Wanli Wang, Linjun Zhao, Jie Chen, Yuqin Song, Jun Zhu, Weiping Liu
Journal: Blood
Blood (2024) 144 (Supplement 1): 6386.
https://doi.org/10.1182/blood-2024-207002
Published: 2024
Journal Articles

Safety and Efficacy of Rocbrutinib in Patients with Relapsed/Refractory Marginal Zone Lymphoma

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Yuqin Song, Qingqing Cai, Keshu Zhou, Ming Jiang, Zhengming Jin, Lei Zhang, Xiuhua Sun, Haiyan Yang, Lanfang Li, Kaiyang Ding, Junyuan Qi, Hongmei Jing, Wei Yang, Min Zhou, Jun Ma, Zhigang Peng, Wei Xu, Hui Zhou, Li Yu, Yuankai Shi, Guohui Cui, Zheng Wang, Nawei Liu, Yejiang Lou, Yue Shen, Yi Chen, Fenlai Tan, Jun Zhu
Journal: Blood
Blood (2024) 144 (Supplement 1): 1635.
https://doi.org/10.1182/blood-2024-194572
Published: 2024
Journal Articles

SKYGLO: A Global Phase III Randomized Study Evaluating Glofitamab Plus Polatuzumab Vedotin + Rituximab, Cyclophosphamide, Doxorubicin, and Prednisone (Pola-R-CHP) Versus Pola-R-CHP in Previously Untreated Patients with Large B-Cell Lymphoma (LBCL)

Free
Ranjana H. Advani, Michael J. Dickinson, Christopher P. Fox, Brad Kahl, Alex F. Herrera, Georg Lenz, Yuqin Song, Rong Tao, Qingqing Cai, Tae Min Kim, Michelle Doral, Derrick Kaufman, Leonardo Roque Pereira, Aurelien Berthier, Franck Morschhauser
Journal: Blood
Blood (2024) 144 (Supplement 1): 1718.1.
https://doi.org/10.1182/blood-2024-194000
Published: 2024
Journal Articles

Preclinical and First-in-Human Phase I Study of Bruton Tyrosine Kinase Degrader HZ-Q1070 in Patients with Recurrent or Refractory B-Cell Malignancies

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Yuqin Song, Ningjing Lin, Xingguo Liu, Yubo Zhou, Yizhe Wu, Xiaomin Luo, Jiangfeng Xie, Xinna Ma, Miao Hu, Yanping Zhang, Jia Li, Xinglu Zhou
Journal: Blood
Blood (2024) 144 (Supplement 1): 6286.
https://doi.org/10.1182/blood-2024-200544
Published: 2024
Journal Articles

BR105 Is a Novel Anti-Sirpα Monoclonal Antibody That Demonstrates a Favorable Safety Profile and Potent Anti-Tumor Efficacy in Patients with Relapsed/Refractory Lymphoid Malignancies: Preliminary Results from a Phase I Study

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Ningjing Lin, Tingting Du, Hui Zhou, Yajun Li, Liang Wang, Xiaomeng Dong, Haochuan Zheng, Jingtao Lu, Mi Tang, Jihua Wu, Wei Zhu, Yuqin Song, Jun Zhu
Journal: Blood
Blood (2024) 144 (Supplement 1): 4175.
https://doi.org/10.1182/blood-2024-206674
Published: 2024
Journal Articles

Study of PC-002 (Sepantronium Bromide), a First-in-Class Inhibitor of Deubiquitinases (DUBs) Targeting Myc Degradation in Relapsed/Refractory c-Myc Rearranged High-Grade B Cell Lymphoma (HGBCL): Updated Phase 2 Results

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Sung-Soo Yoon, Zhiming Li, Seokjin Kim, Ki-Seong Eom, Keshu Zhou, Sung-Nam Lim, Xiaoxi Zhou, Ye Guo, Sung Yong Oh, Huilai Zhang, Hagop Youssoufian, Vernon Jiang, Zanchun Huang, Georgina Kilfoil, Xin Wang, Zhixiang Cao, Xiang LI, Yihai Lin, Alexander Wu, Yiyou Chen, Yuqin Song
Journal: Blood
Blood (2024) 144 (Supplement 1): 3120.
https://doi.org/10.1182/blood-2024-206700
Published: 2024
Journal Articles

Rocbrutinib, a New-Generation BTK Inhibitor, Demonstrates Safety and Efficacy in Relapsed/Refractory Non-GCB Diffuse Large B Cell Lymphoma

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Yuqin Song, Qingqing Cai, Keshu Zhou, Ming Jiang, Zhengming Jin, Lei Zhang, Xiuhua Sun, Haiyan Yang, Lanfang Li, Kaiyang Ding, Junyuan Qi, Hongmei Jing, Wei Yang, Min Zhou, Jun Ma, Zhigang Peng, Wei Xu, Hui Zhou, Li Yu, Yuankai Shi, Guohui Cui, Zheng Wang, Nawei Liu, Yejiang Lou, Yue Shen, Yi Chen, Fenlai Tan, Jun Zhu
Journal: Blood
Blood (2024) 144 (Supplement 1): 3119.
https://doi.org/10.1182/blood-2024-194561
Published: 2024
Journal Articles

Phase Ib/IIa Study of Amulirafusp Alfa (IMM0306) in Combination with Lenalidomide in Patients with Relapsed or Refractory CD20-Positive B-Cell Non-Hodgkin's Lymphoma

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Lijuan Deng, Yanyan Liu, Ningjing Lin, Zhihua Yao, Jiuyang Zhang, Wei Meng, Qiying Lu, Wenzhi Tian, Jun Zhu, Yuqin Song
Journal: Blood
Blood (2024) 144 (Supplement 1): 3033.
https://doi.org/10.1182/blood-2024-200539
Published: 2024
Journal Articles

Time Series Deep Neural Network Identifies Lymphoma Patients Suitable for CAR-T Cell Therapy Using EHR Data

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Meihua Long, Fan Jia, Jili Deng, Jianing Zhang, Ziran Zhao, Yan Xie, Lan Mi, Yan Hou, Yuqin Song
Journal: Blood
Blood (2024) 144 (Supplement 1): 2233.
https://doi.org/10.1182/blood-2024-209699
Published: 2024
Journal Articles

Safety and Efficacy in Patients with Advanced Lymphomas from a Global Phase 1a/1b, First-in-Human Study of CS5001, a Novel Anti-ROR1 ADC

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Yuqin Song, Jian Zhang, Keshu Zhou, Liling Zhang, Minal Barve, Charlotte Lemech, Wenyu Li, Hua-Jay J. Cherng, He Huang, Linna Xie, Richard Zuniga, Caicun Zhou, Lin Shen, Shujun Yang, Sarwan Bishnoi, Yan Zhang, Jingru Wang, Xiaoli Zhu, Fei Li, Jason Yang
Journal: Blood
Blood (2024) 144 (Supplement 1): 1739.
https://doi.org/10.1182/blood-2024-192979
Published: 2024