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Volume 91, Issue 10

May 15 1998

In this Issue

REVIEW ARTICLES
RAPID COMMUNICATIONS
CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS
TRANSPLANTATION
HEMATOPOIESIS
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY
IMMUNOBIOLOGY
NEOPLASIA
PHAGOCYTES
RED CELLS

REVIEW ARTICLES

Endothelial Cells in Physiology and in the Pathophysiology of Vascular Disorders

Douglas B. Cines,Eleanor S. Pollak,Clayton A. Buck,Joseph Loscalzo,Guy A. Zimmerman,Rodger P. McEver,Jordan S. Pober,Timothy M. Wick,Barbara A. Konkle,Bradford S. Schwartz,Elliot S. Barnathan,Keith R. McCrae,Bruce A. Hug,Ann-Marie Schmidt,David M. Stern

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RAPID COMMUNICATIONS

Prothrombin G20210A Mutant Genotype Is a Risk Factor for Cerebrovascular Ischemic Disease in Young Patients

Valerio De Stefano,Patrizia Chiusolo,Katia Paciaroni,Ida Casorelli,Elena Rossi,Marco Molinari,Serenella Servidei,Pietro A. Tonali,Giuseppe Leone

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Activation of Stat-3 Is Involved in the Induction of Apoptosis After Ligation of Major Histocompatibility Complex Class I Molecules on Human Jurkat T Cells

Søren Skov,Mette Nielsen,Søren Bregenholt,Niels Ødum,Mogens H. Claesson

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Genetic Polymorphisms in the Tumor Necrosis Factor Locus Influence Non-Hodgkin's Lymphoma Outcome

Krzysztof Warzocha,Patricia Ribeiro,Jacques Bienvenu,Pascal Roy,Carole Charlot,Dominique Rigal,Bertrand Coiffier,Gilles Salles

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Progressive Telomere Shortening in Aplastic Anemia

Sarah E. Ball,Frances M. Gibson,Siân Rizzo,Jennifer A. Tooze,Judith C.W. Marsh,Edward C. Gordon-Smith

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The Human Intrinsic Factor-Vitamin B₁₂ Receptor,Cubilin: Molecular Characterization and Chromosomal Mapping of the Gene to 10p Within the Autosomal Recessive Megaloblastic Anemia (MGA1) Region

Renata Kozyraki,Mette Kristiansen,Asli Silahtaroglu,Claus Hansen,Christian Jacobsen,Niels Tommerup,Pierre J. Verroust,Søren K. Moestrup

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CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Safety and Cost Effectiveness of a 10 × 10⁹/L Trigger for Prophylactic Platelet Transfusions Compared With the Traditional 20 × 10⁹/L Trigger: A Prospective Comparative Trial in 105 Patients With Acute Myeloid Leukemia

Hannes Wandt,Markus Frank,Gerhard Ehninger,Christiane Schneider,Norbert Brack,Ali Daoud,Irene Fackler-Schwalbe,Jürgen Fischer,Ringfried Gäckle,Thomas Geer,Peter Harms,Birgit Löffler,Siegfried Öhl,Burkhard Otremba,Monika Raab,Petra Schönrock-Nabulsi,Gerhard Strobel,Rolf Winter,Hartmut Link

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A Double-Blind Placebo-Controlled Trial of Granulocyte Colony-Stimulating Factor in Elderly Patients With Previously Untreated Acute Myeloid Leukemia: A Southwest Oncology Group Study (9031)

John E. Godwin,Kenneth J. Kopecky,David R. Head,Cheryl L. Willman,Catherine P. Leith,Harry E. Hynes,Stanley P. Balcerzak,Frederick R. Appelbaum

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Clinical Significance of HLA-DRB1*0410 in Japanese Patients With Idiopathic Thrombocytopenic Purpura

Shosaku Nomura,Tatsunori Matsuzaki,Yoshio Ozaki,Manabu Yamaoka,Chie Yoshimura,Kaoruko Katsura,Gui Lan Xie,Hideo Kagawa,Tomoko Ishida,Shirou Fukuhara

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Clinical Significance of Inhibitors in Acquired von Willebrand Syndrome

Hiroshi Mohri,Shigeki Motomura,Heiwa Kanamori,Michio Matsuzaki,Shin-ichiro Watanabe,Atsuo Maruta,Fumio Kodama,Takao Okubo

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Splenectomy and Risk of Blast Transformation in Myelofibrosis With Myeloid Metaplasia

Giovanni Barosi,Achille Ambrosetti,Antonietta Centra,Antonietta Falcone,Carlo Finelli,Paolo Foa,Alberto Grossi,Roberta Guarnone,Serena Rupoli,Luigiana Luciano,Maria C. Petti,Enrico Pogliani,Domenico Russo,Marco Ruggeri,Silvana Quaglini,the Italian Cooperative Study Group on Myelofibrosis With Myeloid Metaplasia

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TRANSPLANTATION

Long-Term Outcome After Marrow Transplantation for Severe Aplastic Anemia

H. Joachim Deeg,Wendy Leisenring,Rainer Storb,Janet Nims,Mary E.D. Flowers,Robert P. Witherspoon,Jean Sanders,Keith M. Sullivan

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Long-Term Immune Reconstitution and Outcome After HLA-Nonidentical T-Cell–Depleted Bone Marrow Transplantation for Severe Combined Immunodeficiency: A European Retrospective Study of 116 Patients

Elie Haddad,Paul Landais,Wilhelm Friedrich,Bert Gerritsen,M. Cavazzana-Calvo,Gareth Morgan,Yves Bertrand,Anders Fasth,Fulvio Porta,Andrew Cant,Theresa Espanol,Susannah Müller,Paul Veys,Jaak Vossen,Alain Fischer

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Semiquantitative Epstein-Barr Virus (EBV) Polymerase Chain Reaction for the Determination of Patients at Risk for EBV-Induced Lymphoproliferative Disease After Stem Cell Transplantation

Kenneth G. Lucas,Robert L. Burton,Sarah E. Zimmerman,Jinghong Wang,Kenneth G. Cornetta,Kent A. Robertson,Chao H. Lee,David J. Emanuel

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Dose-Intensive Melphalan With Blood Stem-Cell Support for the Treatment of AL (Amyloid Light-Chain) Amyloidosis: Survival and Responses in 25 Patients

Raymond L. Comenzo,Evan Vosburgh,Rodney H. Falk,Vaishali Sanchorawala,Johann Reisinger,Simon Dubrey,Laura M. Dember,John L. Berk,Gorgun Akpek,Michael LaValley,Carl O'Hara,Charles F. Arkin,Daniel G. Wright,Martha Skinner

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Toxicity and Efficacy of Defined Doses of CD4⁺ Donor Lymphocytes for Treatment of Relapse After Allogeneic Bone Marrow Transplant

Edwin P. Alyea,Robert J. Soiffer,Christine Canning,Donna Neuberg,Robert Schlossman,Christopher Pickett,Heather Collins,Yulan Wang,Kenneth C. Anderson,Jerome Ritz

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Lymphohematopoietic Engraftment in Minimally Myeloablated Hosts

F.M. Stewart,S. Zhong,J. Wuu,C.-c. Hsieh,S.K. Nilsson,P.J. Quesenberry

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Engraftment of Cultured Human Hematopoietic Cells in Sheep

Yoshifumi Shimizu,Makio Ogawa,Masao Kobayashi,Graca Almeida-Porada,Esmail D. Zanjani

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HEMATOPOIESIS

Delayed Targeting of Cytokine-Nonresponsive Human Bone Marrow CD34⁺ Cells With Retrovirus-Mediated Gene Transfer Enhances Transduction Efficiency and Long-Term Expression of Transduced Genes

Ponnazhagan Veena,Christie M. Traycoff,David A. Williams,Jon McMahel,Susan Rice,Ken Cornetta,Edward F. Srour

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Myeloid Development Is Selectively Disrupted in PU.1 Null Mice

Karen L. Anderson,Kent A. Smith,Kris Conners,Scott R. McKercher,Richard A. Maki,Bruce E. Torbett

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Endomitosis of Human Megakaryocytes Are Due to Abortive Mitosis

Natacha Vitrat,Karine Cohen-Solal,Claudine Pique,Jean Pierre LeCouedic,Françoise Norol,Annette K. Larsen,André Katz,William Vainchenker,Najet Debili

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Human CD34⁺ Bone Marrow Cells Regulate Stromal Production of Interleukin-6 and Granulocyte Colony-Stimulating Factor and Increase the Colony-Stimulating Activity of Stroma

Pankaj Gupta,Bruce R. Blazar,Kalpna Gupta,Catherine M. Verfaillie

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Lyn Physically Associates With the Erythropoietin Receptor and May Play a Role in Activation of the Stat5 Pathway

Hiroshi Chin,Ayako Arai,Hiroshi Wakao,Ryuichi Kamiyama,Nobuyuki Miyasaka,Osamu Miura

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SHP-1 Phosphatase C-Terminus Interacts With Novel Substrates p32/p30 During Erythropoietin and Interleukin-3 Mitogenic Responses

Wentian Yang,Mina Tabrizi,Karim Berrada,Taolin Yi

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Enhanced Megakaryocyte and Erythroid Development From Normal Human CD34⁺ Cells: Consequence of Enforced Expression of SCL

Ngaire J. Elwood,Helen Zogos,Daniel S. Pereira,John E. Dick,C. Glenn Begley

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Human Hematopoietic Progenitors Express Erythropoietin

T. Stopka,J.H. Zivny,P. Stopkova,J.F. Prchal,J.T. Prchal

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The Effects of Colony-Stimulating Factor-1 on the Distribution of Mononuclear Phagocytes in the Developing Osteopetrotic Mouse

Philip Roth,Melissa G. Dominguez,E. Richard Stanley

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HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

The Carboxyl-Terminal Region of Protein C Is Essential for Its Secretion

Akira Katsumi,Tetsuhito Kojima,Takao Senda,Tomio Yamazaki,Hiroaki Tsukamoto,Isamu Sugiura,Shigeru Kobayashi,Toshiyuki Miyata,Hideaki Umeyama,Hidehiko Saito

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Platelet Aggregation Induced by a Monoclonal Antibody to the A1 Domain of von Willebrand Factor

Hilde Depraetere,Nadine Ajzenberg,Jean-Pierre Girma,Catherine Lacombe,Dominique Meyer,Hans Deckmyn,Dominique Baruch

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Tissue-Specific Expression of Functional Platelet Factor XI Is Independent of Plasma Factor XI Expression

Chang-jun Hu,Frank A. Baglia,David C.B. Mills,Barbara A. Konkle,Peter N. Walsh

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Simple Collagen-Like Peptides Support Platelet Adhesion Under Static But Not Under Flow Conditions: Interaction Via α2β1 and von Willebrand Factor With Specific Sequences in Native Collagen Is a Requirement to Resist Shear Forces

Marilyn W. Verkleij,Laurence F. Morton,C. Graham Knight,Philip G. de Groot,Michael J. Barnes,Jan J. Sixma

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IMMUNOBIOLOGY

Effect of L-Carnitine on Human Immunodeficiency Virus-1 Infection-Associated Apoptosis: A Pilot Study

Sonia Moretti,Edoardo Alesse,Luisa Di Marzio,Francesca Zazzeroni,Barbara Ruggeri,Sonia Marcellini,Giuseppe Famularo,Seth M. Steinberg,Antonio Boschini,M. Grazia Cifone,Claudio De Simone

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Demonstration of Kaposi's Sarcoma-Associated Herpes Virus Cyclin D Homolog in Cutaneous Kaposi's Sarcoma by Colorimetric In Situ Hybridization Using a Catalyzed Signal Amplification System

Jon A. Reed,Roland G. Nador,David Spaulding,Yoichi Tani,Ethel Cesarman,Daniel M. Knowles

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Novel Evidence of Expression and Activity of Ecto-Phospholipase C γ1 in Human T Lymphocytes

Sebastiano Miscia,Angela Di Baldassarre,Amelia Cataldi,Rosa Alba Rana,Valerio Di Valerio,Giuseppe Sabatino

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In Vivo Tropism of Hepatitis C Virus Genomic Sequences in Hematopoietic Cells: Influence of Viral Load, Viral Genotype, and Cell Phenotype

Hervé Lerat,Sylvie Rumin,François Habersetzer,Françoise Berby,Mary-Anne Trabaud,Christian Trépo,Geneviève Inchauspé

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Stable Transduction of the Interleukin-2 Gene Into Human Natural Killer Cell Lines and Their Phenotypic and Functional Characterization In Vitro and In Vivo

Shigeki Nagashima,Robbie Mailliard,Yoshiro Kashii,Torsten E. Reichert,Ronald B. Herberman,Paul Robbins,Theresa L. Whiteside

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Biologically Active Fas Antigen and Its Cognate Ligand Are Expressed on Plasma Membrane-Derived Extracellular Vesicles

Joseph Albanese,Sarkis Meterissian,Maria Kontogiannea,Catherine Dubreuil,Arthur Hand,Sandra Sorba,Nicholas Dainiak

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Functional Diversity of the CD8⁺ T-Cell Response to Epstein-Barr Virus (EBV): Implications for the Pathogenesis of EBV-Associated Lymphoproliferative Disorders

Rachel A. Nazaruk,Rosemary Rochford,Monte V. Hobbs,Martin J. Cannon

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Interleukin-13 Receptor α′ But Not α Chain: A Functional Component of Interleukin-4 Receptors

Takashi Murata,Jun Taguchi,Raj K. Puri

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Expression of CD86 on Human Marrow CD34⁺ Cells Identifies Immunocompetent Committed Precursors of Macrophages and Dendritic Cells

Rita E. Ryncarz,Claudio Anasetti

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CD44 Selectively Associates With Active Src Family Protein Tyrosine Kinases Lck and Fyn in Glycosphingolipid-Rich Plasma Membrane Domains of Human Peripheral Blood Lymphocytes

Subburaj Ilangumaran,Anne Briol,Daniel C. Hoessli

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NEOPLASIA

Constitutive Chemokine Production Results in Activation of Leukocyte Function-Associated Antigen-1 on Adult T-Cell Leukemia Cells

Yoshiya Tanaka,Shinichiro Mine,Carl G. Figdor,Atsushi Wake,Hideyasu Hirano,Junichi Tsukada,Megumi Aso,Koichi Fujii,Kazuyoshi Saito,Yvette van Kooyk,Sumiya Eto

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Inactivation of the ATM Gene in T-Cell Prolymphocytic Leukemias

Dominique Stoppa-Lyonnet,Jean Soulier,Anthony Laugé,Hélène Dastot,Richard Garand,François Sigaux,Marc-Henri Stern

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Secondary Mutation Maintains the Transformed State in BaF3 Cells With Inducible BCR/ABL Expression

Kevin M. Klucher,David V. Lopez,George Q. Daley

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Mutation of CD95 (Fas/Apo-1) Gene in Adult T-Cell Leukemia Cells

Sadahiro Tamiya,Ken-ichiro Etoh,Hitoshi Suzushima,Kiyoshi Takatsuki,Masao Matsuoka

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CD95 (APO-1/Fas) Mutations in Childhood T-Lineage Acute Lymphoblastic Leukemia

Christian Beltinger,Elke Kurz,Thomas Böhler,Martin Schrappe,Wolf-Dieter Ludwig,Klaus-Michael Debatin

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The Ig Heavy Chain 3′ End Confers a Posttranscriptional Processing Advantage to Bcl-2–IgH Fusion RNA in t(14;18) Lymphoma

Alexander Scheidel Petrovic,Robert L. Young,Bernadette Hilgarth,Peter Ambros,Stanley J. Korsmeyer,Ulrich Jaeger

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PHAGOCYTES

Clinical Value of Soluble IgG Fc Receptor Type III in Plasma From Patients With Chronic Idiopathic Neutropenia

Harry R. Koene,Masja de Haas,Marion Kleijer,Tom W.J. Huizinga,Dirk Roos,Albert E.G.Kr. von dem Borne

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The Related Adhesion Focal Tyrosine Kinase (RAFTK) Is Tyrosine Phosphorylated and Participates in Colony-Stimulating Factor-1/Macrophage Colony-Stimulating Factor Signaling in Monocyte-Macrophages

William C. Hatch,Ramesh K. Ganju,Dananagoud Hiregowdara,Shalom Avraham,Jerome E. Groopman

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RED CELLS

The Effect of Apotransferrin on Iron Release From Caco-2 Cells, an Intestinal Epithelial Cell Line

Xavier Alvarez-Hernandez,Margaret Smith,Jonathan Glass

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Examination of Ferrochelatase Mutations That Cause Erythropoietic Protoporphyria

V.M. Sellers,T.A. Dailey,H.A. Dailey

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Treatment of Myeloproliferative Disorders With Hydroxyurea: Effects on Red Blood Cell Geometry and Deformability

K. Gunnar Engström,Eva Löfvenberg

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Safety and Efficacy of Elranatamab in Patients with Relapsed and/or Refractory immunoglobulin Light-Chain Amyloidosis

Donor-derived CD7 CAR T cells for pediatric and adult relapsed/refractory T-ALL/LBL: a phase 2 trial

Inhibiting JAK1: lowering CRS, CAR stays on track

Dissecting JAK2V617F’s double life with and without MPL

Hematological aspects of colchicine poisoning

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Issue Archive

Table of Contents

REVIEW ARTICLES

Endothelial Cells in Physiology and in the Pathophysiology of Vascular Disorders Free

RAPID COMMUNICATIONS

Prothrombin G20210A Mutant Genotype Is a Risk Factor for Cerebrovascular Ischemic Disease in Young Patients Free

Activation of Stat-3 Is Involved in the Induction of Apoptosis After Ligation of Major Histocompatibility Complex Class I Molecules on Human Jurkat T Cells Free

Genetic Polymorphisms in the Tumor Necrosis Factor Locus Influence Non-Hodgkin's Lymphoma Outcome Free

Progressive Telomere Shortening in Aplastic Anemia Free

The Human Intrinsic Factor-Vitamin B12 Receptor,Cubilin: Molecular Characterization and Chromosomal Mapping of the Gene to 10p Within the Autosomal Recessive Megaloblastic Anemia (MGA1) Region Free

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Safety and Cost Effectiveness of a 10 × 109/L Trigger for Prophylactic Platelet Transfusions Compared With the Traditional 20 × 109/L Trigger: A Prospective Comparative Trial in 105 Patients With Acute Myeloid Leukemia Free

A Double-Blind Placebo-Controlled Trial of Granulocyte Colony-Stimulating Factor in Elderly Patients With Previously Untreated Acute Myeloid Leukemia: A Southwest Oncology Group Study (9031) Free

Clinical Significance of HLA-DRB1*0410 in Japanese Patients With Idiopathic Thrombocytopenic Purpura Free

Clinical Significance of Inhibitors in Acquired von Willebrand Syndrome Free

Splenectomy and Risk of Blast Transformation in Myelofibrosis With Myeloid Metaplasia Free

TRANSPLANTATION

Long-Term Outcome After Marrow Transplantation for Severe Aplastic Anemia Free

Long-Term Immune Reconstitution and Outcome After HLA-Nonidentical T-Cell–Depleted Bone Marrow Transplantation for Severe Combined Immunodeficiency: A European Retrospective Study of 116 Patients Free

Semiquantitative Epstein-Barr Virus (EBV) Polymerase Chain Reaction for the Determination of Patients at Risk for EBV-Induced Lymphoproliferative Disease After Stem Cell Transplantation Free

Dose-Intensive Melphalan With Blood Stem-Cell Support for the Treatment of AL (Amyloid Light-Chain) Amyloidosis: Survival and Responses in 25 Patients Free

Toxicity and Efficacy of Defined Doses of CD4+ Donor Lymphocytes for Treatment of Relapse After Allogeneic Bone Marrow Transplant Free

Lymphohematopoietic Engraftment in Minimally Myeloablated Hosts Free

Engraftment of Cultured Human Hematopoietic Cells in Sheep Free

HEMATOPOIESIS

Delayed Targeting of Cytokine-Nonresponsive Human Bone Marrow CD34+ Cells With Retrovirus-Mediated Gene Transfer Enhances Transduction Efficiency and Long-Term Expression of Transduced Genes Free

Myeloid Development Is Selectively Disrupted in PU.1 Null Mice Free

Endomitosis of Human Megakaryocytes Are Due to Abortive Mitosis Free

Human CD34+ Bone Marrow Cells Regulate Stromal Production of Interleukin-6 and Granulocyte Colony-Stimulating Factor and Increase the Colony-Stimulating Activity of Stroma Free

Lyn Physically Associates With the Erythropoietin Receptor and May Play a Role in Activation of the Stat5 Pathway Free

SHP-1 Phosphatase C-Terminus Interacts With Novel Substrates p32/p30 During Erythropoietin and Interleukin-3 Mitogenic Responses Free

Enhanced Megakaryocyte and Erythroid Development From Normal Human CD34+ Cells: Consequence of Enforced Expression of SCL Free

Human Hematopoietic Progenitors Express Erythropoietin Free

The Effects of Colony-Stimulating Factor-1 on the Distribution of Mononuclear Phagocytes in the Developing Osteopetrotic Mouse Free

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

The Carboxyl-Terminal Region of Protein C Is Essential for Its Secretion Free

Platelet Aggregation Induced by a Monoclonal Antibody to the A1 Domain of von Willebrand Factor Free

Tissue-Specific Expression of Functional Platelet Factor XI Is Independent of Plasma Factor XI Expression Free

Simple Collagen-Like Peptides Support Platelet Adhesion Under Static But Not Under Flow Conditions: Interaction Via α2β1 and von Willebrand Factor With Specific Sequences in Native Collagen Is a Requirement to Resist Shear Forces Free

IMMUNOBIOLOGY

Effect of L-Carnitine on Human Immunodeficiency Virus-1 Infection-Associated Apoptosis: A Pilot Study Free

Demonstration of Kaposi's Sarcoma-Associated Herpes Virus Cyclin D Homolog in Cutaneous Kaposi's Sarcoma by Colorimetric In Situ Hybridization Using a Catalyzed Signal Amplification System Free

Novel Evidence of Expression and Activity of Ecto-Phospholipase C γ1 in Human T Lymphocytes Free

In Vivo Tropism of Hepatitis C Virus Genomic Sequences in Hematopoietic Cells: Influence of Viral Load, Viral Genotype, and Cell Phenotype Free

Stable Transduction of the Interleukin-2 Gene Into Human Natural Killer Cell Lines and Their Phenotypic and Functional Characterization In Vitro and In Vivo Free

Biologically Active Fas Antigen and Its Cognate Ligand Are Expressed on Plasma Membrane-Derived Extracellular Vesicles Free

Functional Diversity of the CD8+ T-Cell Response to Epstein-Barr Virus (EBV): Implications for the Pathogenesis of EBV-Associated Lymphoproliferative Disorders Free

Interleukin-13 Receptor α′ But Not α Chain: A Functional Component of Interleukin-4 Receptors Free

Expression of CD86 on Human Marrow CD34+ Cells Identifies Immunocompetent Committed Precursors of Macrophages and Dendritic Cells Free

CD44 Selectively Associates With Active Src Family Protein Tyrosine Kinases Lck and Fyn in Glycosphingolipid-Rich Plasma Membrane Domains of Human Peripheral Blood Lymphocytes Free

NEOPLASIA

Constitutive Chemokine Production Results in Activation of Leukocyte Function-Associated Antigen-1 on Adult T-Cell Leukemia Cells Free

Inactivation of the ATM Gene in T-Cell Prolymphocytic Leukemias Free

Secondary Mutation Maintains the Transformed State in BaF3 Cells With Inducible BCR/ABL Expression Free

Mutation of CD95 (Fas/Apo-1) Gene in Adult T-Cell Leukemia Cells Free

CD95 (APO-1/Fas) Mutations in Childhood T-Lineage Acute Lymphoblastic Leukemia Free

The Ig Heavy Chain 3′ End Confers a Posttranscriptional Processing Advantage to Bcl-2–IgH Fusion RNA in t(14;18) Lymphoma Free

PHAGOCYTES

Clinical Value of Soluble IgG Fc Receptor Type III in Plasma From Patients With Chronic Idiopathic Neutropenia Free

The Related Adhesion Focal Tyrosine Kinase (RAFTK) Is Tyrosine Phosphorylated and Participates in Colony-Stimulating Factor-1/Macrophage Colony-Stimulating Factor Signaling in Monocyte-Macrophages Free

RED CELLS

The Effect of Apotransferrin on Iron Release From Caco-2 Cells, an Intestinal Epithelial Cell Line Free

Examination of Ferrochelatase Mutations That Cause Erythropoietic Protoporphyria Free

Treatment of Myeloproliferative Disorders With Hydroxyurea: Effects on Red Blood Cell Geometry and Deformability Free

Email alerts

ASH Publications

American Society of Hematology

Endothelial Cells in Physiology and in the Pathophysiology of Vascular Disorders

Prothrombin G20210A Mutant Genotype Is a Risk Factor for Cerebrovascular Ischemic Disease in Young Patients

Activation of Stat-3 Is Involved in the Induction of Apoptosis After Ligation of Major Histocompatibility Complex Class I Molecules on Human Jurkat T Cells

Genetic Polymorphisms in the Tumor Necrosis Factor Locus Influence Non-Hodgkin's Lymphoma Outcome

Progressive Telomere Shortening in Aplastic Anemia

The Human Intrinsic Factor-Vitamin B₁₂ Receptor,Cubilin: Molecular Characterization and Chromosomal Mapping of the Gene to 10p Within the Autosomal Recessive Megaloblastic Anemia (MGA1) Region

Safety and Cost Effectiveness of a 10 × 10⁹/L Trigger for Prophylactic Platelet Transfusions Compared With the Traditional 20 × 10⁹/L Trigger: A Prospective Comparative Trial in 105 Patients With Acute Myeloid Leukemia

A Double-Blind Placebo-Controlled Trial of Granulocyte Colony-Stimulating Factor in Elderly Patients With Previously Untreated Acute Myeloid Leukemia: A Southwest Oncology Group Study (9031)

Clinical Significance of HLA-DRB1*0410 in Japanese Patients With Idiopathic Thrombocytopenic Purpura

Clinical Significance of Inhibitors in Acquired von Willebrand Syndrome

Splenectomy and Risk of Blast Transformation in Myelofibrosis With Myeloid Metaplasia

Long-Term Outcome After Marrow Transplantation for Severe Aplastic Anemia

Long-Term Immune Reconstitution and Outcome After HLA-Nonidentical T-Cell–Depleted Bone Marrow Transplantation for Severe Combined Immunodeficiency: A European Retrospective Study of 116 Patients

Semiquantitative Epstein-Barr Virus (EBV) Polymerase Chain Reaction for the Determination of Patients at Risk for EBV-Induced Lymphoproliferative Disease After Stem Cell Transplantation

Dose-Intensive Melphalan With Blood Stem-Cell Support for the Treatment of AL (Amyloid Light-Chain) Amyloidosis: Survival and Responses in 25 Patients

Toxicity and Efficacy of Defined Doses of CD4⁺ Donor Lymphocytes for Treatment of Relapse After Allogeneic Bone Marrow Transplant

Lymphohematopoietic Engraftment in Minimally Myeloablated Hosts

Engraftment of Cultured Human Hematopoietic Cells in Sheep

Delayed Targeting of Cytokine-Nonresponsive Human Bone Marrow CD34⁺ Cells With Retrovirus-Mediated Gene Transfer Enhances Transduction Efficiency and Long-Term Expression of Transduced Genes

Myeloid Development Is Selectively Disrupted in PU.1 Null Mice

Endomitosis of Human Megakaryocytes Are Due to Abortive Mitosis

Human CD34⁺ Bone Marrow Cells Regulate Stromal Production of Interleukin-6 and Granulocyte Colony-Stimulating Factor and Increase the Colony-Stimulating Activity of Stroma

Lyn Physically Associates With the Erythropoietin Receptor and May Play a Role in Activation of the Stat5 Pathway

SHP-1 Phosphatase C-Terminus Interacts With Novel Substrates p32/p30 During Erythropoietin and Interleukin-3 Mitogenic Responses

Enhanced Megakaryocyte and Erythroid Development From Normal Human CD34⁺ Cells: Consequence of Enforced Expression of SCL

Human Hematopoietic Progenitors Express Erythropoietin

The Effects of Colony-Stimulating Factor-1 on the Distribution of Mononuclear Phagocytes in the Developing Osteopetrotic Mouse

The Carboxyl-Terminal Region of Protein C Is Essential for Its Secretion

Platelet Aggregation Induced by a Monoclonal Antibody to the A1 Domain of von Willebrand Factor

Tissue-Specific Expression of Functional Platelet Factor XI Is Independent of Plasma Factor XI Expression

Simple Collagen-Like Peptides Support Platelet Adhesion Under Static But Not Under Flow Conditions: Interaction Via α2β1 and von Willebrand Factor With Specific Sequences in Native Collagen Is a Requirement to Resist Shear Forces

Effect of L-Carnitine on Human Immunodeficiency Virus-1 Infection-Associated Apoptosis: A Pilot Study

Demonstration of Kaposi's Sarcoma-Associated Herpes Virus Cyclin D Homolog in Cutaneous Kaposi's Sarcoma by Colorimetric In Situ Hybridization Using a Catalyzed Signal Amplification System

Novel Evidence of Expression and Activity of Ecto-Phospholipase C γ1 in Human T Lymphocytes

In Vivo Tropism of Hepatitis C Virus Genomic Sequences in Hematopoietic Cells: Influence of Viral Load, Viral Genotype, and Cell Phenotype

Stable Transduction of the Interleukin-2 Gene Into Human Natural Killer Cell Lines and Their Phenotypic and Functional Characterization In Vitro and In Vivo

Biologically Active Fas Antigen and Its Cognate Ligand Are Expressed on Plasma Membrane-Derived Extracellular Vesicles

Functional Diversity of the CD8⁺ T-Cell Response to Epstein-Barr Virus (EBV): Implications for the Pathogenesis of EBV-Associated Lymphoproliferative Disorders

Interleukin-13 Receptor α′ But Not α Chain: A Functional Component of Interleukin-4 Receptors

Expression of CD86 on Human Marrow CD34⁺ Cells Identifies Immunocompetent Committed Precursors of Macrophages and Dendritic Cells

CD44 Selectively Associates With Active Src Family Protein Tyrosine Kinases Lck and Fyn in Glycosphingolipid-Rich Plasma Membrane Domains of Human Peripheral Blood Lymphocytes

Constitutive Chemokine Production Results in Activation of Leukocyte Function-Associated Antigen-1 on Adult T-Cell Leukemia Cells

Inactivation of the ATM Gene in T-Cell Prolymphocytic Leukemias

Secondary Mutation Maintains the Transformed State in BaF3 Cells With Inducible BCR/ABL Expression

Mutation of CD95 (Fas/Apo-1) Gene in Adult T-Cell Leukemia Cells

CD95 (APO-1/Fas) Mutations in Childhood T-Lineage Acute Lymphoblastic Leukemia

The Ig Heavy Chain 3′ End Confers a Posttranscriptional Processing Advantage to Bcl-2–IgH Fusion RNA in t(14;18) Lymphoma

Clinical Value of Soluble IgG Fc Receptor Type III in Plasma From Patients With Chronic Idiopathic Neutropenia

The Related Adhesion Focal Tyrosine Kinase (RAFTK) Is Tyrosine Phosphorylated and Participates in Colony-Stimulating Factor-1/Macrophage Colony-Stimulating Factor Signaling in Monocyte-Macrophages

The Effect of Apotransferrin on Iron Release From Caco-2 Cells, an Intestinal Epithelial Cell Line

Examination of Ferrochelatase Mutations That Cause Erythropoietic Protoporphyria

Treatment of Myeloproliferative Disorders With Hydroxyurea: Effects on Red Blood Cell Geometry and Deformability