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A dose-ranging study evaluating once-daily oral administration of the factor Xa inhibitor rivaroxaban in the treatment of patients with acute symptomatic deep vein thrombosis: the Einstein–DVT Dose-Ranging Study
A prospective clinicopathologic study of dose-modified CODOX-M/IVAC in patients with sporadic Burkitt lymphoma defined using cytogenetic and immunophenotypic criteria (MRC/NCRI LY10 trial)
Adoptive immunotherapy for indolent non-Hodgkin lymphoma and mantle cell lymphoma using genetically modified autologous CD20-specific T cells
A GABP-binding element in the Robo4 promoter is necessary for endothelial expression in vivo
The Mll partial tandem duplication: differential, tissue-specific activity in the presence or absence of the wild-type allele
Chronic graft-versus-host disease following umbilical cord blood transplantation: retrospective survey involving 1072 patients in Japan
Issue Archive
September 15 2008
In this Issue
Table of Contents
INSIDE BLOOD
ASH 50TH ANNIVERSARY REVIEWS
PLENARY PAPERS
REVIEW ARTICLES
HOW I TREAT
CHEMOKINES, CYTOKINES, AND INTERLEUKINS
CLINICAL TRIALS AND OBSERVATIONS
A dose-ranging study evaluating once-daily oral administration of the factor Xa inhibitor rivaroxaban in the treatment of patients with acute symptomatic deep vein thrombosis: the Einstein–DVT Dose-Ranging Study
Clinical Trials & Observations
Harry R. Buller,Anthonie W. A. Lensing,Martin H. Prins,Giancarlo Agnelli,Alexander Cohen,Alexander S. Gallus,Frank Misselwitz,Gary Raskob,Sebastian Schellong,Annelise Segers,on behalf of the Einstein–DVT Dose-Ranging Study investigators
A prospective clinicopathologic study of dose-modified CODOX-M/IVAC in patients with sporadic Burkitt lymphoma defined using cytogenetic and immunophenotypic criteria (MRC/NCRI LY10 trial)
Clinical Trials & Observations
Graham M. Mead,on behalf of the UK National Cancer Research Institute Lymphoma Clinical Studies Group and the Australasian Leukaemia and Lymphoma Group,Sharon L. Barrans,on behalf of the UK National Cancer Research Institute Lymphoma Clinical Studies Group and the Australasian Leukaemia and Lymphoma Group,Wendi Qian,on behalf of the UK National Cancer Research Institute Lymphoma Clinical Studies Group and the Australasian Leukaemia and Lymphoma Group,Jan Walewski,on behalf of the UK National Cancer Research Institute Lymphoma Clinical Studies Group and the Australasian Leukaemia and Lymphoma Group,John A. Radford,on behalf of the UK National Cancer Research Institute Lymphoma Clinical Studies Group and the Australasian Leukaemia and Lymphoma Group,Max Wolf,on behalf of the UK National Cancer Research Institute Lymphoma Clinical Studies Group and the Australasian Leukaemia and Lymphoma Group,Simon M. Clawson,on behalf of the UK National Cancer Research Institute Lymphoma Clinical Studies Group and the Australasian Leukaemia and Lymphoma Group,Sally P. Stenning,on behalf of the UK National Cancer Research Institute Lymphoma Clinical Studies Group and the Australasian Leukaemia and Lymphoma Group,Claire L. Yule,on behalf of the UK National Cancer Research Institute Lymphoma Clinical Studies Group and the Australasian Leukaemia and Lymphoma Group,Andrew S. Jack,on behalf of the UK National Cancer Research Institute Lymphoma Clinical Studies Group and the Australasian Leukaemia and Lymphoma Group
Adoptive immunotherapy for indolent non-Hodgkin lymphoma and mantle cell lymphoma using genetically modified autologous CD20-specific T cells
Clinical Trials & Observations
Brian G. Till,Michael C. Jensen,Jinjuan Wang,Eric Y. Chen,Brent L. Wood,Harvey A. Greisman,Xiaojun Qian,Scott E. James,Andrew Raubitschek,Stephen J. Forman,Ajay K. Gopal,John M. Pagel,Catherine G. Lindgren,Philip D. Greenberg,Stanley R. Riddell,Oliver W. Press
GENE THERAPY
HEMATOPOIESIS AND STEM CELLS
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY
A GABP-binding element in the Robo4 promoter is necessary for endothelial expression in vivo
Brief Report
Yoshiaki Okada,Enjing Jin,Vesna Nikolova-Krstevski,Kiichiro Yano,Ju Liu,David Beeler,Katherine Spokes,Mie Kitayama,Nobuaki Funahashi,Takefumi Doi,Lauren Janes,Takashi Minami,Peter Oettgen,William C. Aird
IMMUNOBIOLOGY
Antibody fucosylation differentially impacts cytotoxicity mediated by NK and PMN effector cells
Matthias Peipp,Jeroen J. Lammerts van Bueren,Tanja Schneider-Merck,Wim W. K. Bleeker,Michael Dechant,Thomas Beyer,Roland Repp,Patrick H. C. van Berkel,Tom Vink,Jan G. J. van de Winkel,Paul W. H. I. Parren,Thomas Valerius
Multiple ITAM-coupled NK-cell receptors engage the Bcl10/Malt1 complex via Carma1 for NF-κB and MAPK activation to selectively control cytokine production
Olaf Gross,Christina Grupp,Christian Steinberg,Stephanie Zimmermann,Dominikus Strasser,Nicole Hannesschläger,Wolfgang Reindl,Helena Jonsson,Hairong Huo,Dan R. Littman,Christian Peschel,Wayne M. Yokoyama,Anne Krug,Jürgen Ruland
NEOPLASIA
The hematopoietic stem cell compartment of JAK2V617F-positive myeloproliferative disorders is a reflection of disease heterogeneity
Chloe James,Frederic Mazurier,Sabrina Dupont,Ronan Chaligne,Isabelle Lamrissi-Garcia,Micheline Tulliez,Eric Lippert,François-Xavier Mahon,Jean-Max Pasquet,Gabriel Etienne,François Delhommeau,Stephane Giraudier,William Vainchenker,Hubert de Verneuil
Targeting MEK/MAPK signal transduction module potentiates ATO-induced apoptosis in multiple myeloma cells through multiple signaling pathways
Paolo Lunghi,Nicola Giuliani,Laura Mazzera,Guerino Lombardi,Micaela Ricca,Attilio Corradi,Anna Maria Cantoni,Luigi Salvatore,Roberta Riccioni,Antonio Costanzo,Ugo Testa,Massimo Levrero,Vittorio Rizzoli,Antonio Bonati
Oncogenic Kit controls neoplastic mast cell growth through a Stat5/PI3-kinase signaling cascade
Noria Harir,Cédric Boudot,Katrin Friedbichler,Karoline Sonneck,Rudin Kondo,Séverine Martin-Lannerée,Lukas Kenner,Marc Kerenyi,Saliha Yahiaoui,Valérie Gouilleux-Gruart,Jean Gondry,Laurence Bénit,Isabelle Dusanter-Fourt,Kaïss Lassoued,Peter Valent,Richard Moriggl,Fabrice Gouilleux
Molecular basis of bortezomib resistance: proteasome subunit β5 (PSMB5) gene mutation and overexpression of PSMB5 protein
Ruud Oerlemans,Niels E. Franke,Yehuda G. Assaraf,Jacqueline Cloos,Ina van Zantwijk,Celia R. Berkers,George L. Scheffer,Kabir Debipersad,Katharina Vojtekova,Clara Lemos,Joost W. van der Heijden,Bauke Ylstra,Godefridus J. Peters,Gertjan L. Kaspers,Ben A. C. Dijkmans,Rik J. Scheper,Gerrit Jansen
FIP1L1/PDGFRα synergizes with SCF to induce systemic mastocytosis in a murine model of chronic eosinophilic leukemia/hypereosinophilic syndrome
Yoshiyuki Yamada,Abel Sanchez-Aguilera,Eric B. Brandt,Melissa McBride,Nabeel J. H. Al-Moamen,Fred D. Finkelman,David A. Williams,Jose A. Cancelas,Marc E. Rothenberg
The Mll partial tandem duplication: differential, tissue-specific activity in the presence or absence of the wild-type allele
Brief Report
Adrienne M. Dorrance,Shujun Liu,Anita Chong,Benjamin Pulley,David Nemer,Martin Guimond,Weifeng Yuan,Dennis Chang,Susan P. Whitman,Guido Marcucci,Michael A. Caligiuri
PHAGOCYTES
RED CELLS
Retention of Plasmodium falciparum ring-infected erythrocytes in the slow, open microcirculation of the human spleen
Innocent Safeukui,Jean-Michel Correas,Valentine Brousse,Déborah Hirt,Guillaume Deplaine,Sébastien Mulé,Mickael Lesurtel,Nicolas Goasguen,Alain Sauvanet,Anne Couvelard,Sophie Kerneis,Huot Khun,Inès Vigan-Womas,Catherine Ottone,Thierry Jo Molina,Jean-Marc Tréluyer,Odile Mercereau-Puijalon,Geneviève Milon,Peter H. David,Pierre A. Buffet
TRANSFUSION MEDICINE
TRANSPLANTATION
Chronic graft-versus-host disease following umbilical cord blood transplantation: retrospective survey involving 1072 patients in Japan
Brief Report
Hiroto Narimatsu,for the Japan Cord Blood Bank Network,Shigesaburo Miyakoshi,for the Japan Cord Blood Bank Network,Takuhiro Yamaguchi,for the Japan Cord Blood Bank Network,Masahiro Kami,for the Japan Cord Blood Bank Network,Tomoko Matsumura,for the Japan Cord Blood Bank Network,Koichiro Yuji,for the Japan Cord Blood Bank Network,Naoko Murashige,for the Japan Cord Blood Bank Network,Eiji Kusumi,for the Japan Cord Blood Bank Network,Yuko Kodama,for the Japan Cord Blood Bank Network,Tsunehiko Komatsu,for the Japan Cord Blood Bank Network,Hisashi Sakamaki,for the Japan Cord Blood Bank Network,Yasushi Kouzai,for the Japan Cord Blood Bank Network,Masaya Okada,for the Japan Cord Blood Bank Network,Yuko Osugi,for the Japan Cord Blood Bank Network,Ryoji Kobayashi,for the Japan Cord Blood Bank Network,Masami Inoue,for the Japan Cord Blood Bank Network,Satoshi Takahashi,for the Japan Cord Blood Bank Network,Shunro Kai,for the Japan Cord Blood Bank Network,Koji Kato,for the Japan Cord Blood Bank Network,Tokiko Inoue-Nagamura,for the Japan Cord Blood Bank Network,Shuichi Taniguchi,for the Japan Cord Blood Bank Network,Shunichi Kato,for the Japan Cord Blood Bank Network
CORRESPONDENCE
Response: Statistical power and validation of the MIPI
Eva Hoster,Martin Dreyling,Michael Unterhalt,for the German Low-Grade Lymphoma Study Group (GLSG) and the European MCL Network
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Cover Image
Cover Image
![issue cover]()
Partial karyotypes of leukemia-associated chromosomal translocations discovered by Dr Janet Rowley and described in the article that begins on page 2183.
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