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Journal Articles

Multipopulation GWAS for venous thromboembolism identifies novel loci followed by experimental validation in zebrafish

Open Access
Brooke N. Wolford, Queena Yakun Zhao, Kuan-Han H. Wu, Xinge Yu, Catherine E. Richter, Laxmi Bhatta, Ben M. Brumpton, Karl C. Desch, Florian Thibord, Derek Klarin, Andrew D. Johnson, David-Alexandre Trégouët, Scott M. Damrauer, Nicholas L. Smith, Valeria Lo Faro, Kristin Tsuo, Mark J. Daly, Benjamin M. Neale, Wei Zhou, Cristen J. Willer, Jordan A. Shavit, Ida Surakka
Journal: Blood Advances
Blood Adv (2025) 9 (19): 4850–4859.
https://doi.org/10.1182/bloodadvances.2024015790
Published: 2025
Includes: Supplemental data
Journal Articles

BaR-based cryo-EM of platelet integrin αIIbβ3

Open Access
Sneha Singh, Arijit Biswas
Journal: Blood Advances
Blood Adv (2025) 9 (18): 4654–4655.
https://doi.org/10.1182/bloodadvances.2025017161
Published: 2025
Journal Articles

Comments and concerns on the analysis of DAPS-ITP trial

Open Access
Aarti Vibhakar, Shaan D. Shah, Ashwin Patel
Journal: Blood Advances
Blood Adv (2025) 9 (18): 4736–4737.
https://doi.org/10.1182/bloodadvances.2025017207
Published: 2025
Journal Articles

Platelet glycosylation in myelodysplastic syndromes correlates with disease severity

Open Access
Katelyn E. Rosenbalm, Tin Long Wong, Donny Hoang, Valerie L. Andersen, George Steinhardt, Shikan Zheng, Elizabeth A. Griffiths, Tongjun Gu, Karin M. Hoffmeister, Joseph T. Y. Lau, Michael J. Nemeth
Journal: Blood Advances
Blood Adv (2025) 9 (18): 4656–4660.
https://doi.org/10.1182/bloodadvances.2025016349
Published: 2025
Includes: Supplemental data
Journal Articles

Induction of Moderate DNA Damage Enhances Megakaryopoiesis and Platelet Production

Open Access
Virginia Camacho, Roelof Bekendam, Andrew P Stone, Maria N Barrachina, Siobhan Branfield, Estelle Carminita, Isabelle C Becker, Dong H Lee, Ethan Walsey, Clementine Payne, Jakub Piotr Kaplan, Julia Tilburg, Sharmistha Pal, Luis Francisco Zirnberger Batista, Joseph E Italiano, Jr, Kellie R Machlus
Journal: Blood Advances
Blood Adv bloodadvances.2025017375.
https://doi.org/10.1182/bloodadvances.2025017375
Published: 2025
Includes: Multimedia, Supplemental data
Journal Articles

Elucidating the dynamics of integrin αIIbβ3 from native platelet membranes by cryo-EM with build-and-retrieve method

Open Access
Xu Han, Zhemin Zhang, Chih-Chia Su, Meinan Lyu, Masaru Miyagi, Edward Yu, Marvin T. Nieman
Journal: Blood Advances
Blood Adv (2025) 9 (18): 4592–4606.
https://doi.org/10.1182/bloodadvances.2025016209
Published: 2025
Includes: Multimedia, Supplemental data
Journal Articles

Beyond Platelet Counts: Assessing Safety of Post-Splenectomy TPO-RA Use in ITP

Open Access
Ruah Alyamany, Damon E Houghton, Meera Sridharan, Rajiv K Pruthi, Surbhi Shah, Richard C. Godby, Alexandra P Wolanskyj-Spinner, Ronald S. Go
Journal: Blood Advances
Blood Adv bloodadvances.2025017902.
https://doi.org/10.1182/bloodadvances.2025017902
Published: 2025
Includes: Supplemental data
Journal Articles

STAT1-mediated epigenetic regulation of LIN28A controls iPSC-derived platelet production through the let-7–RALB axis

Open Access
Kazuya Hashimoto, Si Jing Chen, Kosuke Fujio, Akihiro Kayama, Naoshi Sugimoto, Naoya Takayama, Moritoki Egi, Koji Eto
Journal: Blood Advances
Blood Adv (2025) 9 (17): 4345–4356.
https://doi.org/10.1182/bloodadvances.2024015557
Published: 2025
Includes: Supplemental data
Journal Articles

Efficacy of Eculizumab Discontinuation in Atypical Hemolytic Uremic Syndrome: A Systematic Review and Meta-analysis

Open Access
Amy Hockman, Sydney Anuskiewicz, Emily Brennan, Saifur R. Chowdhury, Alexander Coltoff, Jacqueline N Poston, Charles S. Greenberg, Benjamin Djulbegovic
Journal: Blood Advances
Blood Adv bloodadvances.2025017004.
https://doi.org/10.1182/bloodadvances.2025017004
Published: 2025
Includes: Supplemental data
Journal Articles

Post-transfusion recovery, quality and metabolism of short and long-term stored platelets during controlled inflammation

Open Access
Stefan F. van Wonderen, Floor L.F. van Baarle, Philippa G. Phelp, Esther B. Bulle, Amy Argabright, Sanne de Bruin, Anita M. Tuip-de Boer, Chantal A. Polet, Rombout B.E. van Amstel, Endry H.T. Lim, Jimmy Schenk, Anna-Linda L. Peters, Robin van Bruggen, Julie A. Reisz, Christie Vermeulen, Thomas R.L. Klei, Bart J. Biemond, Marcella C.A. Müller, Angelo D'Alessandro, Alexander P.J. Vlaar
Journal: Blood Advances
Blood Adv bloodadvances.2025016853.
https://doi.org/10.1182/bloodadvances.2025016853
Published: 2025
Includes: Supplemental data
Journal Articles

The immune receptor FcRg-chain mediates CD36-induced platelet activation and thrombosis by oxidised low-density lipoproteins.

Open Access
Katie S Wraith, Jawad S Khalil, Ahmed Aburima, Lih Tyng Cheah, Matthew S Hindle, Martin Berger, Romez Uddin, Hoor Ayub, Mary McKay, Rui-Gang Xu, Robert A S Ariëns, Mark T Kearney, Michael G Tomlinson, Khalid M. Naseem
Journal: Blood Advances
Blood Adv bloodadvances.2024015652.
https://doi.org/10.1182/bloodadvances.2024015652
Published: 2025
Includes: Supplemental data
Journal Articles

An αIIbβ3 ligand-mimetic murine monoclonal antibody that produces platelet activation by engaging the FcγIIa receptor

Open Access
Jialing Wang, Lorena Buitrago, Lu Wang, Jihong Li, Thomas Walz, Barry S. Coller
Journal: Blood Advances
Blood Adv (2025) 9 (14): 3518–3529.
https://doi.org/10.1182/bloodadvances.2024015368
Published: 2025
Includes: Supplemental data
Journal Articles

Critical bleeding in adults and children with immune thrombocytopenia: a multicenter cohort study

Open Access
Emily Sirotich, Saifur R. Chowdhury, Dimpy Modi, Gordon Guyatt, Melanie St John, Kerolos Eisa, Adam Cuker, Carolyn E. Beck, Rachael F. Grace, Justin W. Yan, Shuoyan Ning, Charles T. Quinn, Amanda Pfeiffer, Michele P. Lambert, Karen Panckeri, Allyson Pishko, Kristine VanAarsen, Ahmed Slim, Kathryn Carrier, Rebecca Geer, Abinaya Arulselvan, Matthew Basara, Brenna Cannon, Ellis J. Bloom, Sam J. King, Daya Gill, Laura M. Venier, Emily Xu, Ishaq Siddiqui, Bonnie Liu, Timothy Mercier, Taylah Buissereth, Emily M. Harris, Enass H. Raffa, Joel Livingston, Mahmudur Rahman Chowdhury, Maryam Akbari-Moghaddam, Dongyoung Kim, Lehana Thabane, Dena Zeraatkar, Donald M. Arnold
Journal: Blood Advances
Blood Adv (2025) 9 (13): 3238–3248.
https://doi.org/10.1182/bloodadvances.2024015494
Published: 2025
Journal Articles

Complement C5 inhibition in early onset HELLP syndrome

Open Access
Clinical Trials & Observations
Gloria F. Gerber, Robert A. Brodsky, Arthur Jason Vaught
Journal: Blood Advances
Blood Adv (2025) 9 (13): 3304–3307.
https://doi.org/10.1182/bloodadvances.2024014746
Published: 2025
Includes: Supplemental data
Journal Articles

Clarifying the role of p.Gln723Lys in hTTP prevalence

Open Access
Omid Seidizadeh, Andrea Cairo, Ilaria Mancini, James N. George, Flora Peyvandi
Journal: Blood Advances
Blood Adv (2025) 9 (12): 3024–3025.
https://doi.org/10.1182/bloodadvances.2025016030
Published: 2025
Journal Articles

Safety, efficacy, and treatment satisfaction in adults with ITP who switched to avatrombopag from another TPO-RA

Open Access
Clinical Trials & Observations
Michael D. Tarantino, Kailash Mosalpuria, Scott Kolodny, Jessica Zhang, Michael Vredenburg, Brian D. Jamieson
Journal: Blood Advances
Blood Adv (2025) 9 (11): 2733–2743.
https://doi.org/10.1182/bloodadvances.2024015635
Published: 2025
Includes: Supplemental data
Journal Articles

Impact of HLA alloimmunization on clinical outcomes of severe aplastic anemia treated with immunosuppressive therapy

Open Access
Clinical Trials & Observations
Jibran Durrani, Leonard N. Chen, Ruba N. Shalhoub, Valentina Baez, Joshua Glass, Nu Ri Cha, Xiaoyang Ma, Zhijie Wu, Shouguo Gao, Jennifer Lotter, Olga Rios, Colin O. Wu, Willy A. Flegel, Neal S. Young, Emma M. Groarke, Bhavisha A. Patel
Journal: Blood Advances
Blood Adv (2025) 9 (11): 2639–2650.
https://doi.org/10.1182/bloodadvances.2024015301
Published: 2025
Includes: Supplemental data
Journal Articles

DNMT3A regulates murine megakaryocyte-biased hematopoietic stem cell fate decisions

Open Access
Sarah M. Waldvogel, Virginia Camacho, Dandan Fan, Anna G. Guzman, Alejandra Garcia-Martell, Elmira Khabusheva, Jacey Rodriguez Pridgen, Josephine De La Fuente, Rachel Rau, Ashlyn G. Laidman, Maria N. Barrachina, Estelle Carminita, Justin A. Courson, Michael R. Williamson, Joanne I. Hsu, Chun-Wei Chen, Jaime Reyes, Subhashree Pradhan, Rolando E. Rumbaut, Alan R. Burns, Benjamin Deneen, Jianzhong Su, Kellie R. Machlus, Margaret A. Goodell
Journal: Blood Advances
Blood Adv (2025) 9 (9): 2285–2299.
https://doi.org/10.1182/bloodadvances.2024015061
Published: 2025
Includes: Supplemental data
Journal Articles

Neutrophil recruitment depends on platelet-derived leukotriene B4

Open Access
Christian Hackenbroch, Tugce Cimen, Carina Gross, Stefanie Rubenzucker, Philipp Burkard, Niklas Groß, Robert Ahrends, Tamara Girbl, David Stegner
Journal: Blood Advances
Blood Adv (2025) 9 (9): 2226–2230.
https://doi.org/10.1182/bloodadvances.2024014947
Published: 2025
Includes: Supplemental data
Journal Articles

Efficacy and safety of dapsone in adult primary immune thrombocytopenia

Open Access
Marion Larue, Guillaume Moulis, Manuela Rueter, Sylvain Audia, Thibault Comont, Louis Terriou, Jean-François Viallard, Brigitte Pan-Petesch, Bruno Royer, Bernard Bonnotte, Lionel Galicier, Olivier Lambotte, François Lefrere, Stéphane Cheze, Mikael Ebbo, Tu-Ahn Duong, Emmanuelle Boutin, Laetitia Languille, Matthieu Mahevas, Bertrand Godeau, Florence Canoui-Poitrine, Marc Michel
Journal: Blood Advances
Blood Adv (2025) 9 (8): 1976–1983.
https://doi.org/10.1182/bloodadvances.2024014939
Published: 2025
Includes: Supplemental data