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Kellie R. Machlus
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Journal Articles

Induction of Moderate DNA Damage Enhances Megakaryopoiesis and Platelet Production

Open Access
Virginia Camacho, Roelof Bekendam, Andrew P Stone, Maria N Barrachina, Siobhan Branfield, Estelle Carminita, Isabelle C Becker, Dong H Lee, Ethan Walsey, Clementine Payne, Jakub Piotr Kaplan, Julia Tilburg, Sharmistha Pal, Luis Francisco Zirnberger Batista, Joseph E Italiano, Jr, Kellie R Machlus
Journal: Blood Advances
Blood Adv bloodadvances.2025017375.
https://doi.org/10.1182/bloodadvances.2025017375
Published: 2025
Includes: Multimedia, Supplemental data
Journal Articles

DNMT3A regulates murine megakaryocyte-biased hematopoietic stem cell fate decisions

Open Access
Sarah M. Waldvogel, Virginia Camacho, Dandan Fan, Anna G. Guzman, Alejandra Garcia-Martell, Elmira Khabusheva, Jacey Rodriguez Pridgen, Josephine De La Fuente, Rachel Rau, Ashlyn G. Laidman, Maria N. Barrachina, Estelle Carminita, Justin A. Courson, Michael R. Williamson, Joanne I. Hsu, Chun-Wei Chen, Jaime Reyes, Subhashree Pradhan, Rolando E. Rumbaut, Alan R. Burns, Benjamin Deneen, Jianzhong Su, Kellie R. Machlus, Margaret A. Goodell
Journal: Blood Advances
Blood Adv (2025) 9 (9): 2285–2299.
https://doi.org/10.1182/bloodadvances.2024015061
Published: 2025
Includes: Supplemental data
Journal Articles

SARS-CoV-2 infection modifies the transcriptome of the megakaryocytes in the bone marrow

Free
Isabelle Allaeys, Guillaume Lemaire, Mickaël Leclercq, Emile Lacasse, Maude Fleury, Isabelle Dubuc, Leslie Gudimard, Florian Puhm, Julia Tilburg, Andrew Stone, Kellie R. Machlus, Arnaud Droit, Louis Flamand, Eric Boilard
Journal: Blood Advances
Blood Adv (2024) 8 (11): 2777–2789.
https://doi.org/10.1182/bloodadvances.2023012367
Published: 2024
Includes: Supplemental data
Journal Articles

Peripheral megakaryocytes sound the alarm in COVID-19

Free
Clinical Trials & Observations
Eric Boilard, Kellie R. Machlus
Journal: Blood Advances
Blood Adv (2023) 7 (15): 4197–4199.
https://doi.org/10.1182/bloodadvances.2023010201
Published: 2023
Journal Articles

Platelet-derived extracellular vesicles infiltrate and modify the bone marrow during inflammation

Free
Shauna L. French, Kirill R. Butov, Isabelle Allaeys, Jorge Canas, Golnaz Morad, Patricia Davenport, Audrée Laroche, Natalia M. Trubina, Joseph E. Italiano, Jr., Marsha A. Moses, Martha Sola-Visner, Eric Boilard, Mikhail A. Panteleev, Kellie R. Machlus
Journal: Blood Advances
Blood Adv (2020) 4 (13): 3011–3023.
https://doi.org/10.1182/bloodadvances.2020001758
Published: 2020
Includes: Supplemental data
Journal Articles

Aspirin inhibits platelets from reprogramming breast tumor cells and promoting metastasis

Free
Kelly E. Johnson, Julia R. Ceglowski, Harvey G. Roweth, Jodi A. Forward, Mason D. Tippy, Saleh El-Husayni, Rajesh Kulenthirarajan, Michael W. Malloy, Kellie R. Machlus, Wendy Y. Chen, Joseph E. Italiano, Jr, Elisabeth M. Battinelli
Journal: Blood Advances
Blood Adv (2019) 3 (2): 198–211.
https://doi.org/10.1182/bloodadvances.2018026161
Published: 2019
Includes: Supplemental data
Journal Articles

Mature murine megakaryocytes present antigen-MHC class I molecules to T cells and transfer them to platelets

Free
Anne Zufferey, Edwin R. Speck, Kellie R. Machlus, Rukhsana Aslam, Li Guo, Mark J. McVey, Michael Kim, Rick Kapur, Eric Boilard, Joseph E. Italiano, Jr, John W. Semple
Journal: Blood Advances
Blood Adv (2017) 1 (20): 1773–1785.
https://doi.org/10.1182/bloodadvances.2017007021
Published: 2017
Includes: Supplemental data
Journal Articles

Deletion of the Arp2/3 complex in megakaryocytes leads to microthrombocytopenia in mice

Free
David S. Paul, Caterina Casari, Congying Wu, Raymond Piatt, Swetha Pasala, Robert A. Campbell, Kathryn O. Poe, Dorsaf Ghalloussi, Robert H. Lee, Jeremy D. Rotty, Brian C. Cooley, Kellie R. Machlus, Joseph E. Italiano, Jr, Andrew S. Weyrich, James E. Bear, Wolfgang Bergmeier
Journal: Blood Advances
Blood Adv (2017) 1 (18): 1398–1408.
https://doi.org/10.1182/bloodadvances.2017006973
Published: 2017
Includes: Multimedia, Supplemental data