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Journal Articles

A Modified CALGB-10403 in Hispanic Adolescent and Young Adults with Philadelphia -Negative Acute Lymphoblastic Leukemia: Promising Results Despite a High-Rate of Metabolic and Hepatic Toxicities

Juan Rangel-Patiño, MD, Alvaro Cabrero Garcia, Carolina Balderas-Delgado, MD, Lauro Fabian Amador, MD, Yvette Neme Yunes, Ana Cooke, MD, Adriana Rosas, Roberta Demichelis, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1352.
https://doi.org/10.1182/blood-2019-126108
Published: 2019
Journal Articles

Using Pharmacogenomics Testing to Optimize Care in Children with Acute Hematologic Malignancies

Trisha Kissoon, MD MBA
Journal: Blood
Blood (2019) 134 (Supplement_1): 5062.
https://doi.org/10.1182/blood-2019-129511
Published: 2019
Journal Articles

Combination Thioguanine and Decitabine Is Highly Active in Patients with Advanced Myeloid Malignancies: A Single Institution Experience

Kara Cicero, MD MPH, Mark L Heaney, Todd L. Rosenblat, MD MS, Nicole Lamanna, MD, Joseph G. Jurcic, MD, Mark G. Frattini, MD PhD, Daniel J. Lee, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3899.
https://doi.org/10.1182/blood-2019-130203
Published: 2019
Journal Articles

Pediatric-Inspired Regimens Are Associated with Better Outcomes When Compared with Hypercvad in Hispanic Adolescents and Young Adults with Acute Lymphoblastic Leukemia

Roberta Demichelis, MD, Karla Adriana Espinosa, MD MSc, Juan Rangel-Patiño, MD, Emmanuel Almanza, MD, Ana Cooke, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3877.
https://doi.org/10.1182/blood-2019-125370
Published: 2019
Journal Articles

A Retrospective Review of Mercaptopurine Metabolism Reveals High Rate of Patients with Suboptimal Metabolites Successfully Corrected with Allopurinol

Lauren Marie Vasta, MD, Richard C Zanetti, MD, Dina S. Parekh, MD, Anne B. Warwick, MD MPH, Kenneth Lieuw, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3878.
https://doi.org/10.1182/blood-2019-126184
Published: 2019
Journal Articles

High-Dose Cytarabine Is Indispensable for the Survival of Children with Myeloid Leukemia of Down Syndrome Despite Negative Minimal Residual Disease Post-Induction

Johann K. Hitzler, MD, Jason Berman, MD, Robert B. Gerbing, Amy Beckman, Betsy A Hirsch, PhD, Susana C. Raimondi, PhD, Todd E Druley, MD PhD, Michael R. Loken, PhD, Lisa Eidenschink Brodersen, PhD, Karen Chisholm, Shelton A. Viola, MD, Jeffrey W. Taub, MD, Alan S Gamis, MD MPH, Todd A. Alonzo, PhD, E. Anders Kolb, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 118.
https://doi.org/10.1182/blood-2019-126723
Published: 2019
Journal Articles

A Network Meta-Analysis of Clinical Trials Assessing Induction Chemotherapy in Newly Diagnosed Acute Myeloid Leukemia Among Young Adults

Nour Tlimat, MD, Salman Muddassir, Saad Ullah Malik, Warda Faridi, MD, Qurat Ul Ain Riaz Sipra, MBBS, MD, Faiz Anwer, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1432.
https://doi.org/10.1182/blood-2018-99-119646
Published: 2018
Journal Articles

Treatment of Elderly and Unfit AML Patients with Prolonged Administration of Low Dose Cytarabine and Thioguanine Achieves High Complete Remission Rates in an Outpatient Setting

Christopher K Arthur, Anthony Jeffrey, Molly Forbes, Eva Yip, Vicki Katsioulas, William S. Stevenson, MBBS, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3998.
https://doi.org/10.1182/blood-2018-99-118027
Published: 2018
Journal Articles

Loss of KDM6A Confers Drug Resistance in Acute Myeloid Leukemia

Sophie M. Stief, M.Sc., Anna-Li Hanneforth, Raphael Mattes, Sabrina Weser, M.Sc., Binje Vick, PhD, Michael D. Bartoschek, M.Sc., Helena Domínguez Moreno, M.Sc., Wen-Hsin Liu, PhD, Bianka Ksienzyk, Maja Rothenberg-Thurley, PhD, Hilmar Quentmeier, PhD, Wolfgang Hiddemann, Klaus H. Metzeler, MD, Gunnar Schotta, PhD, Sebastian Bultmann, PhD, Irmela Jeremias, MD PhD, Heinrich Leonhardt, PhD, Karsten Spiekermann, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3935.
https://doi.org/10.1182/blood-2018-99-114959
Published: 2018
Journal Articles

Outcome of Infants Younger Than 1 Year with Acute Lymphoblastic Leukemia Treated with the Interfant-06 Protocol; Results from an International Randomised Study

Rob Pieters, MDPhDMSc, Paola De Lorenzo, PhD, Philip Ancliffe, Luis Alberto Aversa, MD, Benoit Brethon, Andrea Biondi, MD, Myriam Campbell, Gabriele Escherich, Alina Ferster, MD, Rebecca Gardner, MD, Rishi Sury Kotecha, MBBChir, MRCP, FRACP, PhD, Birgitte Lausen, MD, Chi Kong Li, MD, Franco Locatelli, Andishe Attarbaschi, Christina Peters, MD, Jeffrey Rubnitz, MD PhD, Lewis B. Silverman, MD, Jan Stary, MD PhD, Tomasz Szczepanski, MD PhD, Ajay Vora, MD, Martin Schrappe, MD PhD, Maria Grazia Valsecchi, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 655.
https://doi.org/10.1182/blood-2018-99-112854
Published: 2018
Journal Articles

Outcome of Patients with Acute Myeloid Leukemia (AML) Undergoing Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) Beyond First Complete Remission (CR1)

Georg Evers, MD, Dietrich W. Beelen, Jan Braess, MD, Cristina Sauerland, Hans-Jochem Kolb, MD, Albrecht Reichle, MD, Ernst Holler, MD, Rainer Schwerdtfeger, MD, Renate Arnold, MD, Christoph Scheid, MD, Utz Krug, MD, Carsten Müller-Tidow, MD, Christoph Schliemann, MD, Jan-Henrik Mikesch, MD, Georg Lenz, Bernhard J. Wörmann, MD, Wolfgang Hiddemann, Wolfgang E. Berdel, MD, Matthias Stelljes, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4649.
https://doi.org/10.1182/blood-2018-99-116964
Published: 2018
Journal Articles

SETD2 alterations impair DNA damage recognition and lead to resistance to chemotherapy in leukemia

Brenton G. Mar, S. Haihua Chu, Josephine D. Kahn, Andrei V. Krivtsov, Richard Koche, Cecilia A. Castellano, Jacob L. Kotlier, Rebecca L. Zon, Marie E. McConkey, Jonathan Chabon, Ryan Chappell, Peter V. Grauman, James J. Hsieh, Scott A. Armstrong, Benjamin L. Ebert
Journal: Blood
Blood (2017) 130 (24): 2631–2641.
https://doi.org/10.1182/blood-2017-03-775569
Published: 2017
Includes: Supplemental data
Journal Articles

Evaluation of Nudt15 -Guided Thiopurine Dose Individualization In Vivo Using CRISPR/Cas9-Edited Mouse Model

Takaya Moriyama, MDPhD, Rina Nishii, Laura Janke, DVM, PhD, Lie Li, Chen Ru, Scott A Brown, PhD, Ting-Nien Lin, Chase Suiter, Kentaro Kihira, MD, Hidemi Toyoda, MD PhD, Motohiro Kato, MD PhD, Atushi Manabe, MD PhD, Katsuyoshi Koh, MD, Masatoshi Takagi, MD PhD, Hiroki Hori, MD PhD, Jun J. Yang, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3879.
https://doi.org/10.1182/blood.V130.Suppl_1.3879.3879
Published: 2017
Journal Articles

No Association between Relapse Risk and Thiopurine Methyltransferase Activity By Either Geno- or Phenotype in the NOPHO ALL-2008 Protocol

Stine Nygaard Nielsen, PhD MD, Kathrine Grell, PhD, Jacob Nersting, PhD, Jonas Abrahamsson, MD PhD, Bendik Lund, MD PhD, Jukka A. Kanerva, MD, Ólafur G Jónsson, MD, Goda Vaitkeviciene, MD, Kaie Pruunsild, MD, Malin Lindqvist Appell, Lisa Hjalgrim, PhD, Kjeld Schmiegelow, MD DMSc
Journal: Blood
Blood (2017) 130 (Supplement 1): 1279.
https://doi.org/10.1182/blood.V130.Suppl_1.1279.1279
Published: 2017
Journal Articles

Individualized 6-Mercaptopurine Increments in Consolidation Treatment of Childhood Acute Lymphoblastic Leukemia: A NOPHO ALL2008 Randomized Controlled Trial

Morten Tulstrup, MD, Thomas Leth Frandsen, MD PhD, Jonas Abrahamsson, MD PhD, Bendik Lund, MD PhD, Kim Vettenranta, MD PhD, Olafur G. Jonsson, MD PhD, Hanne Vibeke Marquart, MD PhD, Birgitte Klug Albertsen, MD, Mats Heyman, MD PhD, Kjeld Schmiegelow, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 142.
https://doi.org/10.1182/blood.V130.Suppl_1.142.142
Published: 2017
Journal Articles

The Role of MMSET E1099K Mutation in Gene Dysregulation, Drug Resistance and Clonogenicity in Acute B-Lymphoblastic Leukemia

Joanna Pierro, DO, Jason Saliba, PhD, Nikki Ann Evensen, PhD BS, Yixiao Gong, Shella Saint Fleur-Lominy, MDPhD, William L. Carroll, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2474.
https://doi.org/10.1182/blood.V130.Suppl_1.2474.2474
Published: 2017
Journal Articles

Magic-TT Mediated Hematopoietic Stem/Progenitor Cells Promote Hematopoietic Recovery after Autologous Bone Marrow Transplantation

Yongjun Zhou, MD, Qiuxia Zhang, MD, Qiusui Mai, MD, Shan Jiang, Hao Huang, Linlin Zhang, MD, Xiaowei Sun, Minchun Zhang, Pengxin Qiao, Chun Zou, Xiaoli Chen, Zhihao Zheng, Jerry Kitbok Majaw, Qifa Liu, MD, Jing Sun, MD, Qianli Jiang, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4952.
https://doi.org/10.1182/blood.V130.Suppl_1.4952.4952
Published: 2017
Journal Articles

PACSIN2 rs2413739 Polymorphism and Thiopurine Pharmacokinetics: Validation Studies in Pediatric Patients

Gabriele Stocco, PhD, Raffaella Franca, Diego Favretto, Nagua Giurici, Alessandro Ventura, Giuliana Decorti, Luciana Vinti, MD, Antonella Colombini, Erica Brivio, Laura Rachele Bettini, Ilaria Bini, Francesca Sismondi, Alessandra Mandese, Noelia Malusà, Stefano Martelossi, Marco Rabusin
Journal: Blood
Blood (2017) 130 (Supplement 1): 4999.
https://doi.org/10.1182/blood.V130.Suppl_1.4999.4999
Published: 2017
Journal Articles

RAS Pathway Mutations As Predictive Biomarker for Treatment Adaptation in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia

Isabel S. Jerchel, MSc, Alex Q. Hoogkamer, BSc, Ingrid M. Ariës, PhD, Elisabeth M.P. Steeghs, MSc, Judith M. Boer, PhD, Nicolle J.M. Besselink, BSc, Aurélie Boeree, BSc, Cesca van de Ven, PhD, Hester A. de Groot-Kruseman, PhD, Valerie De Haas, MD PhD, Martin A. Horstmann, MD, Gabriele Escherich, MD, Ronald W. Stam, PhD, C. Michel Zwaan, MD PhD, Edwin Cuppen, PhD, Marco J. Koudijs, PhD, Rob Pieters, MD PhD, Monique L. Den Boer, MSc, PhD
Journal: Blood
Blood (2016) 128 (22): 4087.
https://doi.org/10.1182/blood.V128.22.4087.4087
Published: 2016
Journal Articles

Lineage Switch Under Blinatumomab of a Relapsed Common ALL Co-Expressing Myeloid Markers without MLL Rearrangement

Annabel Zoghbi, Beate Winkler, MD, Udo zur Stadt, PhD, Ingo Müller, MD, Gabriele Escherich, MD
Journal: Blood
Blood (2016) 128 (22): 5196.
https://doi.org/10.1182/blood.V128.22.5196.5196
Published: 2016