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Journal Articles

Chronic lymphoproliferative disorder of NK cells with TNFAIP3 and DNMT3A mutations

Philip L. Bulterys, Oscar Silva

Blood (2021) 137 (24): 3460.

https://doi.org/10.1182/blood.2021011812

Published: 2021

Journal Articles

Tracing the roots of CLPD-NK by TET2 and STAT3

Marco Herling, Till Braun

Blood (2021) 137 (23): 3156–3158.

https://doi.org/10.1182/blood.2020010542

Published: 2021

Journal Articles

Linking the KIR phenotype with STAT3 and TET2 mutations to identify chronic lymphoproliferative disorders of NK cells

Cédric Pastoret, Fabienne Desmots, Gaëlle Drillet, Simon Le Gallou, Marie-Laure Boulland, Alexia Thannberger, Anne-Violaine Doncker, Véronique Salaun, Gandhi Laurent Damaj, Richard Veyrat-Masson, Olivier Tournilhac, Aline Moignet, Céline Pangault, Mikaël Roussel, Thierry Fest, Thierry Lamy

Blood (2021) 137 (23): 3237–3250.

https://doi.org/10.1182/blood.2020006721

Published: 2021

Includes: Supplemental data

Journal Articles

Releasing the brake in CAR natural killer cells

Sophia Chen

Blood (2021) 137 (5): 579–581.

https://doi.org/10.1182/blood.2020008993

Published: 2021

Journal Articles

Targeting a cytokine checkpoint enhances the fitness of armored cord blood CAR-NK cells

May Daher, Rafet Basar, Elif Gokdemir, Natalia Baran, Nadima Uprety, Ana Karen Nunez Cortes, Mayela Mendt, Lucila Nassif Kerbauy, Pinaki P. Banerjee, Mayra Shanley, Nobuhiko Imahashi, Li Li, Francesca Lorraine Wei Inng Lim, Mohsen Fathi, Ali Rezvan, Vakul Mohanty, Yifei Shen, Hila Shaim, Junjun Lu, Gonca Ozcan, Emily Ensley, Mecit Kaplan, Vandana Nandivada, Mustafa Bdiwi, Sunil Acharya, Yuanxin Xi, Xinhai Wan, Duncan Mak, Enli Liu, Xin Ru Jiang, Sonny Ang, Luis Muniz-Feliciano, Ye Li, Jing Wang, Shahram Kordasti, Nedyalko Petrov, Navin Varadarajan, David Marin, Lorenzo Brunetti, Richard J. Skinner, Shangrong Lyu, Leiser Silva, Rolf Turk, Mollie S. Schubert, Garrett R. Rettig, Matthew S. McNeill, Gavin Kurgan, Mark A. Behlke, Heng Li, Natalie W. Fowlkes, Ken Chen, Marina Konopleva, Richard E. Champlin, Elizabeth J. Shpall, Katayoun Rezvani

Blood (2021) 137 (5): 624–636.

https://doi.org/10.1182/blood.2020007748

Published: 2021

Includes: Supplemental data

Journal Articles

NK cells: energized yet exhausted in adult HLH

Kim E. Nichols, Melissa R. Hines

Blood (2020) 136 (5): 524–525.

https://doi.org/10.1182/blood.2020006097

Published: 2020

Journal Articles

Functional and genetic testing in adults with HLH reveals an inflammatory profile rather than a cytotoxicity defect

Julien Carvelli, Christelle Piperoglou, Catherine Farnarier, Frédéric Vely, Karin Mazodier, Sandra Audonnet, Patrick Nitschke, Christine Bole-Feysot, Mohamed Boucekine, Audrey Cambon, Mohamed Hamidou, Jean-Robert Harle, Geneviève de Saint Basile, Gilles Kaplanski

Blood (2020) 136 (5): 542–552.

https://doi.org/10.1182/blood.2019003664

Published: 2020

Includes: Supplemental data

Journal Articles

The transcription factor ETS1 is an important regulator of human NK cell development and terminal differentiation

Sylvie Taveirne, Sigrid Wahlen, Wouter Van Loocke, Laura Kiekens, Eva Persyn, Els Van Ammel, Katrien De Mulder, Juliette Roels, Laurentijn Tilleman, Marc Aumercier, Patrick Matthys, Filip Van Nieuwerburgh, Tessa C. C. Kerre, Tom Taghon, Pieter Van Vlierberghe, Bart Vandekerckhove, Georges Leclercq

Blood (2020) 136 (3): 288–298.

https://doi.org/10.1182/blood.2020005204

Published: 2020

Includes: Supplemental data

Journal Articles

A research-driven approach to the identification of novel natural killer cell deficiencies affecting cytotoxic function

Michael T. Lam, Emily M. Mace, Jordan S. Orange

Blood (2020) 135 (9): 629–637.

https://doi.org/10.1182/blood.2019000925

Published: 2020

Journal Articles

Pluripotent stem cell–derived NK cells with high-affinity noncleavable CD16a mediate improved antitumor activity

Huang Zhu, Robert H. Blum, Ryan Bjordahl, Svetlana Gaidarova, Paul Rogers, Tom Tong Lee, Ramzey Abujarour, Gregory B. Bonello, Jianming Wu, Pei-Fang Tsai, Jeffrey S. Miller, Bruce Walcheck, Bahram Valamehr, Dan S. Kaufman

Blood (2020) 135 (6): 399–410.

https://doi.org/10.1182/blood.2019000621

Published: 2020

Includes: Multimedia, Supplemental data

Journal Articles

Single-Cell RNA Sequencing Reveals a Distinct Transcriptome Signature of Hematopoiesis in GATA2 Deficiency

Zhijie Wu, MD PhD, Shouguo Gao, PhD, Sachiko Kajigaya, PhD, Jinguo Chen, PhD, Rongye Shi, BS, Carrie Diamond, MD, Cindy Palmer, BSN, Amy P. Hsu, Katherine R. Calvo, MD PhD, Dennis D. Hickstein, MD, Steven M. Holland, MD, Neal S. Young, MD

Blood (2019) 134 (Supplement_1): 3735.

https://doi.org/10.1182/blood-2019-124774

Published: 2019

Journal Articles

Aberrant SYK Expression As a Potential Therapeutic Target in T/NK Cell Neoplasms

Jing-Ping Zhang, PhD, Qi Gao, MLS, Alexander Chan, MD, Wenbin Xiao, MD PhD, Sary El Daker, PhD, Mikhail Roshal, MD PhD, Ahmet Dogan, MD PhD

Blood (2019) 134 (Supplement_1): 3978.

https://doi.org/10.1182/blood-2019-130406

Published: 2019

Journal Articles

The Combination of the BCL-2 Antagonist Venetoclax with the CD70-Targeting Antibody Cusatuzumab Synergistically Eliminates Primary Human Leukemia Stem Cells

Carsten Riether, PhD, Tanja Chiorazzo, PhD, Amy J. Johnson, PhD, Christina Diane Drenberg, PhD, Khaja Waheeduddin Syed, BPharm, MS, Mahan Moshir, MSc, Anna Hultberg, PhD, Nicolas Leupin, Hans De Haard, Adrian F Ochsenbein, MD

Blood (2019) 134 (Supplement_1): 3918.

https://doi.org/10.1182/blood-2019-127464

Published: 2019

Journal Articles

Functional Characterization of Gamma Delta T Cells and Allogeneic Activated NK Cells As Effector Cells for Tafasitamab (MOR208)

Jung Hyun Her, Dominik Pretscher, Sungyoo Cho, Yu-Kyeong Hwang, Timm Hoeres, Rainer Boxhammer, Stefan Steidl, Maria Patra, Juergen Schanzer, Jan Endell

Blood (2019) 134 (Supplement_1): 3801.

https://doi.org/10.1182/blood-2019-128511

Published: 2019

Journal Articles

Potently Cytotoxic Natural Killer Cell Potential Initially Emerges from Erythro-Myeloid Progenitors during Mammalian Development

Carissa Dege, PhD, Katherine H Fegan, MS, J Philip Creamer, IV, BA,BS, Melissa M Berrien-Elliott, PhD, Stephanie A. Luff, PhD, Julia A Wagner, PhD, Paul D. Kingsley, PhD, Kathleen E. McGrath, PhD, Todd A Fehniger, MD PhD, James Palis, MD, Christopher M. Sturgeon, PhD

Blood (2019) 134 (Supplement_1): 2464.

https://doi.org/10.1182/blood-2019-130347

Published: 2019

Journal Articles

Germline Mutations in ETV6 are Associated with In Vivo cytoplasmic Localization of ETV6 and Cause Transcriptional Dysregulation of Interferon Response Genes

Marlie H Fisher, Greg Kirkpatrick, PhD, Courtney L Jones, PhD, Brett M. Stevens, PhD, Michael Callaghan, MD, Eric Pietras, PhD, Kenneth L. Jones, PhD, Christopher C. Porter, MD, Jorge Di Paola, MD

Blood (2019) 134 (Supplement_1): 2316.

https://doi.org/10.1182/blood-2019-132032

Published: 2019

Journal Articles

Endothelial JAK3 Expression Enhances Pro-Hematopoietic Angiocrine Function of Sinusoidal Endothelial Cells

José Gabriel Barcia Durán, BS

Blood (2019) 134 (Supplement_1): 2488.

https://doi.org/10.1182/blood-2019-122449

Published: 2019

Journal Articles

Whole Exome Sequencing Analysis in Chronic Lymphoproliferative Disorder of NK Cells (CLPD-NK) Patients Fails to Detect Significant Viral Load

Edoardo Giussani, Vanessa Rebecca Gasparini, Alessandro Coppe, Antonella Teramo, Andrea Binatti, Cristina Vicenzetto, Giulia Calabretto, Gregorio Barilà, Francesco Piazza, Gianpietro Semenzato, Stefania Bortoluzzi, PhD, Renato Zambello

Blood (2019) 134 (Supplement_1): 5214.

https://doi.org/10.1182/blood-2019-127907

Published: 2019

Journal Articles

A Clinical Trial of Cannabis As Targeted Therapy for Indolent Leukemic Lymphoma

Christopher M Melén, MD, Magali Merrien, MSc, Agata Wasik, MSc, PhD, Kristina Sonnevi, MD PhD, Henna-Riikka Junlén, MD, Birger Christersson, MD PhD, Birgitta Sander, MD PhD Prof., Björn E Wahlin, MD PhD

Blood (2019) 134 (Supplement_1): 5487.

https://doi.org/10.1182/blood-2019-126693

Published: 2019

Journal Articles

Expression of the Tigit/CD226/CD155 Receptors/Ligand System in Chronic Lymphocytic Leukemia

Francesca Arruga, PhD, Giulia Guerra, Denis Baev, PhD, Catherine Hoofd, PhD, Marta Coscia, MD PhD, Giovanni Francesco D'Arena, MD, Gianluca Gaidano, MD PhD, Richard R. Furman, MD, Silvia Deaglio, MD PhD

Blood (2019) 134 (Supplement_1): 5454.

https://doi.org/10.1182/blood-2019-128308

Published: 2019

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Chronic lymphoproliferative disorder of NK cells with TNFAIP3 and DNMT3A mutations

Tracing the roots of CLPD-NK by TET2 and STAT3

Linking the KIR phenotype with STAT3 and TET2 mutations to identify chronic lymphoproliferative disorders of NK cells

Releasing the brake in CAR natural killer cells

Targeting a cytokine checkpoint enhances the fitness of armored cord blood CAR-NK cells

NK cells: energized yet exhausted in adult HLH

Functional and genetic testing in adults with HLH reveals an inflammatory profile rather than a cytotoxicity defect

The transcription factor ETS1 is an important regulator of human NK cell development and terminal differentiation

A research-driven approach to the identification of novel natural killer cell deficiencies affecting cytotoxic function

Pluripotent stem cell–derived NK cells with high-affinity noncleavable CD16a mediate improved antitumor activity

Single-Cell RNA Sequencing Reveals a Distinct Transcriptome Signature of Hematopoiesis in GATA2 Deficiency

Aberrant SYK Expression As a Potential Therapeutic Target in T/NK Cell Neoplasms

The Combination of the BCL-2 Antagonist Venetoclax with the CD70-Targeting Antibody Cusatuzumab Synergistically Eliminates Primary Human Leukemia Stem Cells

Functional Characterization of Gamma Delta T Cells and Allogeneic Activated NK Cells As Effector Cells for Tafasitamab (MOR208)

Potently Cytotoxic Natural Killer Cell Potential Initially Emerges from Erythro-Myeloid Progenitors during Mammalian Development

Germline Mutations in ETV6 are Associated with In Vivo cytoplasmic Localization of ETV6 and Cause Transcriptional Dysregulation of Interferon Response Genes

Endothelial JAK3 Expression Enhances Pro-Hematopoietic Angiocrine Function of Sinusoidal Endothelial Cells

Whole Exome Sequencing Analysis in Chronic Lymphoproliferative Disorder of NK Cells (CLPD-NK) Patients Fails to Detect Significant Viral Load

A Clinical Trial of Cannabis As Targeted Therapy for Indolent Leukemic Lymphoma

Expression of the Tigit/CD226/CD155 Receptors/Ligand System in Chronic Lymphocytic Leukemia

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