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Journal Articles

Regulation of Platelet Function By Adenosine Receptors

Daniel N. Darlington, PhD, Xiaowu Wu, MD MSc, Kevin L. Chang, BS, James Bynum, PhD, Andrew P. Cap, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2348.
https://doi.org/10.1182/blood-2019-131129
Published: 2019
Journal Articles

Efficacy of OR21, a Novel Oral Demethylating Agent in Chronic Myeloid Leukemia

Kazuharu Kamachi, MD, Hiroshi Ureshino, MD, Nao Yoshida, MD, Yuki Kurahashi, Tatsuro Watanabe, PhD, Seiji Okada, MD PhD, Shinya Kimura, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5365.
https://doi.org/10.1182/blood-2019-125460
Published: 2019
Journal Articles

Phase I Dose Escalation Study of Radiotherapy and Durvalumab (MEDI4736) in Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL): The RaDD Study

Eliza A Hawkes, Kate Manos, Geoff Chong, Jodie Palmer, Michael MacManus, Colm Keane, MD, Andrew Scott, Jake Shortt, MBBS FRACP FRCPA PhD, David Ritchie, MD PhD, Leonid Churilov, Laura Johnston, Tom Witkowski, Allison Barraclough, Sze-Ting Lee, Wendi Lin, Rachel Koldej, Richard Khor
Journal: Blood
Blood (2019) 134 (Supplement_1): 5328.
https://doi.org/10.1182/blood-2019-122635
Published: 2019
Journal Articles

Treatment Outcome and a Practical 10-Point Prognostic Index in Adult Patients with Non-M3 Acute Myeloid Leukemia: A Retrospective, Multicenter Study in Malaysia

Tze Shin Leong, MBBS,MRCP,MSc, Sen Mui Tan, Lee Ping Chew, Tee Chuan Ong, Siew Lian Chong, Kar Ying Yong, Siong Leng Hon, Syazarin Fidhora Nasution, Ching Tiong Ko, Vanusha Devaraja, Andy Sing Ong Tang, Tsen Chuen Jerome Tan, Ngee Siang Lau, Sharifah Shahnaz Syed Abd Kadir, Veena Selvaratnam, Yee Yee Yap, Bee Sun Lee, William Kian Boon Law, Jameela Sathar
Journal: Blood
Blood (2019) 134 (Supplement_1): 2606.
https://doi.org/10.1182/blood-2019-126656
Published: 2019
Journal Articles

Impact of Post-Transplant Consolidative Radiotherapy in Patients with Relapsed or Refractory Classical Hodgkin Lymphoma and a PET-CT Based Predictive Model for Relapse

Collin Chin, MBBS, Andrew Wirth, MBBS, MD FRACP, FRANZCR, David Ritchie, MD PhD, Michael Hofman, MBBS (Hons), FRACP, FAANMS, Michael MacManus, John F. Seymour, MBBS, PhD FRACP, Belinda Campbell, MBBS, MMed, FRANZCR, Michael Dickinson, MBBS,FRACP,FRCPA
Journal: Blood
Blood (2019) 134 (Supplement_1): 4044.
https://doi.org/10.1182/blood-2019-122716
Published: 2019
Journal Articles

Lentiviral Gene Therapy with Autologous Hematopoietic Stem and Progenitor Cells (HSPCs) for the Treatment of Severe Combined Immune Deficiency Due to Adenosine Deaminase Deficiency (ADA-SCID): Results in an Expanded Cohort

Donald B. Kohn, MD, Kit L. Shaw, PhD, Elizabeth Garabedian, RN, MS, Denise Ann Carbonaro-Sarracino, PhD, Theodore B. Moore, MD, Satiro N. De Oliveira, MD, Gay M. Crooks, MD, John Tse, Sally Shupien, Dayna Terrazas, Alejandra Davila, Amalia Icreverzi, PhD, Allen Yu, Krista M. Chun, Christian E. Casas, Provaboti Barman, PhD, Maritess Coronel, Beatriz Campo Fernandez, PhD, Ruixue Zhang, Roger P. Hollis, PhD, Chilenwa Uzowuru, Hilory Ricketts, Jinhua Xu Bayford, Valentina Trevisan, Serena Arduini, PhD, Frances Lynn, Mahesh Kudari, MBBS, MA, Andrea Spezzi, MD MBBS, Lilith Reeves, MS, MT(ASCP), Kenneth Cornetta, Robert A. Sokolic, MD, Roberta Parrott, BS, Rebecca Buckley, MD, Claire Booth, Fabio Candotti, MD, Harry L. Malech, MD, Adrian J. Thrasher, MBBS, PhD FMedSci, H. Bobby Gaspar, MBBS, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3345.
https://doi.org/10.1182/blood-2019-123432
Published: 2019
Journal Articles

Targeting DNA Damage and Repair in Acute Myeloid Leukemia Carrying Internal Tandem Duplication of Fms-like Tyrosine Kinase 3 (FLT3-ITD) - a Mechanistic Study

Ka Lam Nelson Ng, PhD, Claire Lynn, Thomas Wing Yan Leung, Eric Chi Wai So, PhD, Anskar Yu Hung Leung, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1261.
https://doi.org/10.1182/blood-2019-129472
Published: 2019
Journal Articles

The MEK Inhibitor Trametinib Enhances Diverse T Cell Reconstitution with Suppressing Xenogeneic Graft-Versus-Host-Disease

Hidekazu Itamura, MD PhD, Hiroyuki Muranushi, MD, Takero Shindo, MD PhD, Kazutaka Kitaura, DVM, PhD, Seiji Okada, MD PhD, Tadasu Shin-I, PhD, Ryuji Suzuki, DVM, PhD, Akifumi Takaori-Kondo, MD PhD, Shinya Kimura, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1929.
https://doi.org/10.1182/blood-2019-128913
Published: 2019
Journal Articles

Dissecting the Immune Cell Progeny of CAR-Expressing Hematopoietic Stem Cells in a Humanized Mouse Model

Heng-Yi Liu, Nezia Rahman, Tzu-Ting Chiou, PhD, Satiro N. De Oliveira, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4640.
https://doi.org/10.1182/blood-2019-129746
Published: 2019
Journal Articles

A Prognostic Model Integrating PET-Derived Quantitative Parameters and Image Texture Analyses Using Radiomics in a Large Prospective Phase III Trial, GOYA

Lale Kostakoglu, MD MPH, Paola Berchialla, PhD, Federico Dalmasso, PhD, Larry A Pierce, PhD, Umberto Vitolo, Maurizio Martelli, MD, Laurie H Sehn, MD, Marek Trněný, MD, Tina G Nielsen, MD PhD, Christopher R Bolen, PhD, Deniz Sahin, BSc, Calvin Lee, MD, Tarec Christoffer C. El-Galaly, MD, Federico Mattiello, PhD, Paul E Kinahan, PhD, Stephane Chauvie, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 883.
https://doi.org/10.1182/blood-2019-123450
Published: 2019
Journal Articles

Anti-Leukemic Activity of Single Agent Venetoclax in Newly Diagnosed Acute Myeloid Leukemia: A Sub-Set Analysis of the Caveat Study

Chong Chyn Chua, MBBS, John Reynolds, PhD, Jessica M Salmon, PhD, Chun Fong, Stephen B Ting, MB BS, FRACP, FRCPA, PhD, Ing Soo Tiong, MBBS,FRACP,FRCPA, Shaun Fleming, MBBS,, Sarah MacRaild, Donia M Moujalled, PhD, Giovanna Pomilio, Nik Cummings, Julie McManus, Adam Ivey, BSc, MSc, PhD, Purvi M Kakadia, PhD, Stefan K. Bohlander, MD, Andrew W. Roberts, MBBS, PhD FRACP, FRCPA, Andrew H. Wei, PhD FRACP, FRCPA, MBBS
Journal: Blood
Blood (2019) 134 (Supplement_1): 462.
https://doi.org/10.1182/blood-2019-126640
Published: 2019
Journal Articles

Acquisition of the Recurrent Gly101Val Mutation in BCL2 Confers Resistance to Venetoclax in Patients with Progressive Chronic Lymphocytic Leukemia

Piers Blombery, MBBS, Mary Ann Anderson, FRACP, FRCPA, MBBS, Jianan Gong, PhD, Rachel Thijssen, Richard W Birkinshaw, PhD, Ella Thompson, PhD, Charis E Teh, PhD, Tamia Nguyen, Zhen Xu, PhD, Christoffer Flensburg, PhD, Thomas Lew, MBBS, Ian Majewski, PhD, Daniel Gray, David Alan Westerman, MBBS, FRCPA, FRACP, Constantine S. Tam, MBBS (Hons), MD FRACP, FRCPA, John F. Seymour, MBBS, PhD, Peter E Czabotar, PhD, David Huang, Andrew W. Roberts, MBBS, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): LBA-7.
https://doi.org/10.1182/blood-2018-120761
Published: 2018
Journal Articles

Exhausted CLL T Cells Mediated By PD1 Expression an Important Mechanism for CD19 CAR Efficacy in CLL in the Adoptive Transfer TCL1 Mouse Model

Robin Sanderson, MRCP, FRCPath, Arantxa Romero-Toledo, MSc, John G. Gribben
Journal: Blood
Blood (2018) 132 (Supplement 1): 4537.
https://doi.org/10.1182/blood-2018-99-111180
Published: 2018
Journal Articles

AUGMENT: A Phase III Randomized Study of Lenalidomide Plus Rituximab (R 2 ) Vs Rituximab/Placebo in Patients with Relapsed/Refractory Indolent Non-Hodgkin Lymphoma

John P. Leonard, MD, Marek Trněný, Koji Izutsu, MDPhD, Nathan H. Fowler, MD, Xiaonan Hong, MD, Jun Zhu, Huilai Zhang, MDPhD, Fritz Offner, MD, Adriana Scheliga, MD, Grzegorz S. Nowakowski, MD, Antonio Pinto, MD, Francesca Re, MDPhD, Laura Maria Fogliatto, MD, Phillip Scheinberg, MD, Ian W. Flinn, MD PhD, Cláudia Moreira, MD, David Liu, MDPhD, Stacey Kalambakas, MD, Pierre Fustier, PhD, Chengqing Wu, PhD, John G. Gribben
Journal: Blood
Blood (2018) 132 (Supplement 1): 445.
https://doi.org/10.1182/blood-2018-99-110861
Published: 2018
Journal Articles

Interim Results from an Ongoing Phase 2 Multicenter Study of Tazemetostat, an EZH2 Inhibitor, in Patients with Relapsed or Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL)

Vincent Ribrag, Franck Morschhauser, Pamela McKay, MD, Gilles Andre Salles, Connie Lee Batlevi, MD, Anna Schmitt, Herve Tilly, MD, Guillaume Cartron, Catherine Thieblemont, MD, Christophe Fruchart, John G. Gribben, Thierry Lamy, Steven Le Gouill, Reda Bouabdallah, MD, Michael Dickinson, MD, Stephen Opat, Deyaa Adib, Stephen J Blakemore, John Larus, Peter Johnson, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4196.
https://doi.org/10.1182/blood-2018-99-113411
Published: 2018
Journal Articles

Tocilizumab to Prevent Infusion-Related Events in Patients with Chronic Lymphocytic Leukemia and Co-Morbidities Treated with Obinutuzumab and Chlorambucil: Results from the Randomized Phase Ib GALACTA Trial

Ciara Louise Freeman, MRCP, MSc, FRCPath, MBBChir, Sebastian Böttcher, Javier De la Serna, Julio Delgado, Franca Falzetti, Marco Gobbi, MD, Sandra Lejniece, Maria Chiara Di Bernardo, Navita L Mallalieu, Tina Nielsen, Andrea Knapp, John G. Gribben
Journal: Blood
Blood (2018) 132 (Supplement 1): 4419.
https://doi.org/10.1182/blood-2018-99-118238
Published: 2018
Journal Articles

Updated Report on Identification of Molecular Predictors of Tazemetostat Response in an Ongoing NHL Phase 2 Study

Alice McDonald, Elizabeth Thomas, Scott Daigle, Franck Morschhauser, Gilles Salles, MD PhD, Vincent Ribrag, Pamela McKay, MD, Herve Tilly, MD, Anna Schmitt, Connie Lee Batlevi, MD, Christophe Fruchart, Peter Johnson, MD, Michael Dickinson, MD, Stephen Opat, Wojciech Jurczak, Guillaume Cartron, Thierry Lamy, Pier Luigi Zinzani, MD, Sarit Assouline, John Radford, MD FRCP, John G. Gribben, Corinne Haioun, MD, Aristeidis Chaidos, MD PhD, Steven Le Gouill, MD PhD, Alicia Clawson, John Larus, Stephen J Blakemore
Journal: Blood
Blood (2018) 132 (Supplement 1): 4097.
https://doi.org/10.1182/blood-2018-99-115132
Published: 2018
Journal Articles

Immunoglobulin Variable Region Gene Sequences Reveal N-Glycosylation Motifs As an Early and Stable Event in Follicular Lymphoma Pathology

Mariette Odabashian, BSc, Emanuela Carlotti, PhD BSc, Shamzah Araf, MRCP, MBBS, Jessica Okosun, MD PhD, Francesco Forconi, MD DM, PhD FRCPath, Freda K Stevenson, PhD, John G. Gribben, Maria Calaminici, MD PhD, Sergey Krysov, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4101.
https://doi.org/10.1182/blood-2018-99-112397
Published: 2018
Journal Articles

Prognostic Impact of Time from Diagnosis to Initial Chemotherapy for Acute Myeloid Leukemia

Yoshimasa Kamoda, MD, Akira Hangaishi, MD PhD, Hiroki Hayashida, MD, Yusuke Uchibori, MD, Hiromitsu Iizuka, MD PhD, Michiko Kida, MD PhD, Kensuke Usuki, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3981.
https://doi.org/10.1182/blood-2018-99-111123
Published: 2018
Journal Articles

Addition of Gemtuzumab Ozogamicin (GO) to Fludarabine, Cytarabine and G-CSF (FLAG) Based Induction Regimen Results in Better Early Molecular Response and Relapse Free Survival Compared to Idarubicin (FLAG-Ida) in Newly Diagnosed Core Binding Factor Leukemia

Gautam Borthakur, MD, Jorge E. Cortes, MD, Guillermo Garcia-Manero, MD, Keyur Patel, MD PhD, Farhad Ravandi, MD, Tapan M. Kadia, MD, Naveen Pemmaraju, MD, Naval G. Daver, MD, Musa Yilmaz, MD, Zeev E. Estrov, MD, Maro N. Ohanian, DO, Rita Maduike, Hagop M. Kantarjian, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3993.
https://doi.org/10.1182/blood-2018-99-118591
Published: 2018