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Journal Articles

Donor regulatory T-cell therapy to prevent graft-versus-host disease

Available to Purchase
Clinical Trials & Observations
Everett H. Meyer, Anna Pavlova, Alejandro Villar-Prados, Cameron Bader, Bryan Xie, Lori Muffly, Paige Kim, Katherine Sutherland, Sushma Bharadwaj, Saurabh Dahiya, Matthew Frank, Sally Arai, Laura Johnston, David Miklos, Andrew Rezvani, Parveen Shiraz, Surbhi Sidana, Judy Shizuru, Wen-Kai Weng, Vaibhav Agrawal, Amy Putnam, Nathaniel Fernhoff, John Tamarisis, Ying Lu, Rahul D. Pawar, J. Scott McClellan, Robert Lowsky, Robert S. Negrin
Journal: Blood
Blood (2025) 145 (18): 2012–2024.
https://doi.org/10.1182/blood.2024026446
Published: 2025
Includes: Supplemental data
Journal Articles

Prognostic Understanding for Older, Medically Infirm, and/or Frail Recipients of Allogeneic Hematopoietic Cell Transplantation in an Ongoing Seamless Phase 2/3 Randomized Interventional Trial (ACE-BMT)

Free
Elizabeth T. Loggers, James Fausto, Matthew Givens, Mei-Ean Yeow, Reena V. Jayani, Hassan B Alkhateeb, Laura A Schoenherr, Michael W. Rabow, Mark B Juckett, George Carrum, Joseph Uberti, Kyle Neale, Santiago Lopez, Diana Martins-Welch, Jeanette G Ferrer, Laura S Rhee, Drew A Rosielle, Susan McInnes, Jason A Webb, Rachel J. Cook, Elisheva Newman, Ronald Sobecks, Laura Johnston, Mohamed Sorror
Journal: Blood
Blood (2024) 144 (Supplement 1): 2297.
https://doi.org/10.1182/blood-2024-212281
Published: 2024
Journal Articles

The Composite Health Risk Assessment Model (CHARM) Predicts Risks of Toxicities, Functional and Cognitive Decline Among Survivors of Allogeneic Hematopoietic Cell Transplantation (allo-HCT): A Prospective BMT-CTN Study 1704

Free
Mohamed Sorror, Wael Saber, Brent R. Logan, Nancy Geller, Anna Bellach, Jianqun Kou, William A. Wood, John M. McCarty, Thomas G. Knight, Lyndsey Runaas, Laura Johnston, Jeremy Walston, Ryotaro Nakamura, Asmita Mishra, Joseph Uberti, Parastoo B Dahi, Jennifer N. Saultz, Shannon R McCurdy, Lawrence E Morris, Philip Imus, William J. Hogan, Kalyan Nadiminti, Vijaya Raj Bhatt, Rebecca Olin, Joseph E. Maakaron, Ronald Sobecks, Sarah A. Wall, Deborah Mattila, Bailey Protz, Steven M. Devine, Mary M. Horowitz, Andrew Artz
Journal: Blood
Blood (2024) 144 (Supplement 1): 685.
https://doi.org/10.1182/blood-2024-194414
Published: 2024
Journal Articles

Safe and Effective Combination of Donor-Derived, Allogeneic CD19/CD22-CAR T Cells with Myeloablative Graft-Engineered Allo-HCT for High-Risk B-ALL

Free
Lori Muffly, Snegha Ananth, Lindsay Danley, Caroline Wagner, Diana Kordek, Kimi DeNoble, Ayesha Fraser, Emily Egeler, Alfonso Molina, Zachary Ehlinger, Moksha Desai, Hossein Daghagh, Ramya Tunuguntla, Annie K. Brown, Raquel Ibañez, Anne Marijn Kramer, Zinaida Good, Sally Arai, Laura Johnston, Robert Lowsky, Andrew R. Rezvani, Judith Shizuru, Lekha Mikkilineni, Parveen Shiraz, Surbhi Sidana, Wen-Kai Weng, Vanessa E. Kennedy, Sushma Bharadwaj, Saurabh Dahiya, Matthew J. Frank, Everett H. Meyer, Robert S. Negrin, Steven A. Feldman, Crystal L. Mackall, Bita Sahaf, David B. Miklos, Melody Smith
Journal: Blood
Blood (2024) 144 (Supplement 1): 679.
https://doi.org/10.1182/blood-2024-211959
Published: 2024
Journal Articles

CD22-Directed CAR T-Cell Therapy for Large B-Cell Lymphomas Progressing after CD19-Directed CAR T-Cell Therapy: Continued Durable Remissions at 3-Year Follow-up

Free
Anne Marijn Kramer, John H. Baird, Hrishikesh Srinagesh, Emily Egeler, Kendall Levine, Annie K. Brown, Sharon Mavroukakis, Kristen Cunanan, Yi-Jiun Su, Neha Agarwal, Mark P. Hamilton, Sushma Bharadwaj, Sally Arai, Laura Johnston, Robert Lowsky, Everett H. Meyer, Robert S. Negrin, Andrew R. Rezvani, Judith Shizuru, Lekha Mikkilineni, Hitomi Hosoya, Parveen Shiraz, Surbhi Sidana, Wen-Kai Weng, Vanessa E. Kennedy, Melody Smith, Saurabh Dahiya, Kara L. Davis, Sneha Ramakrishna, Liora Michal Schultz, Ramya Tunuguntla, Steven A. Feldman, Lori Muffly, Crystal L. Mackall, David B. Miklos, Matthew J. Frank
Journal: Blood
Blood (2024) 144 (Supplement 1): 69.
https://doi.org/10.1182/blood-2024-198544
Published: 2024
Journal Articles

Single Institution Analysis of Lymphoma Treatment Related Post-CAR Myeloid Neoplasms

Free
Mark Hamilton, Nick Phillips, Dasom Lee, Zachary Ehlinger, Anne Marijn Kramer, Hrishikesh Srinagesh, Zinaida Good, Xiaoman Kang, Mari Olsen, Chih Long Liu, Feng Tian, Brian J. Sworder, Hitomi Hosoya, Joseph G. Schroers-Martin, Sushma Bharadwaj, Sally Arai, Laura Johnston, Robert Lowsky, Everett H. Meyer, Robert S. Negrin, Andrew R. Rezvani, Judith Shizuru, Lekha Mikkilineni, Parveen Shiraz, Surbhi Sidana, Wen-Kai Weng, Vanessa E. Kennedy, Melody Smith, Lori Muffly, David Kurtz, Saurabh Dahiya, Matthew J. Frank, Crystal L. Mackall, Bita Sahaf, David B. Miklos, Ash A. Alizadeh
Journal: Blood
Blood (2024) 144 (Supplement 1): 96.
https://doi.org/10.1182/blood-2024-205378
Published: 2024
Journal Articles

A Standard Operating Protocol for Pre-Transplant Low Dose Splenic Radiotherapy for Patients with Myelofibrosis

Free
Claire Baniel, Natalie Park, Daniella Klebaner, William Shomali, Jason Gotlib, Sally Arai, Susan Hiniker, Richard T. Hoppe, Laura Johnston, Michael S. Binkley
Journal: Blood
Blood (2024) 144 (Supplement 1): 2116.
https://doi.org/10.1182/blood-2024-206503
Published: 2024
Journal Articles

CD22-Directed CAR T-Cell Therapy Achieves Complete Remission in CD19-Directed CAR T-Cell Refractory Follicular and Mantle Cell Lymphoma

Free
Anne Marijn Kramer, Hrishikesh Srinagesh, Yi-Jiun Su, Mark P. Hamilton, Kendall Levine, Eleonora Migliore, Kimi DeNoble, Annie K. Brown, Kristen Cunanan, Neha Agarwal, Claire Lohman, Sharon Mavroukakis, Sushma Bharadwaj, Sally Arai, Laura Johnston, Robert Lowsky, Everett H. Meyer, Robert S. Negrin, Andrew R. Rezvani, Judith Shizuru, Lekha Mikkilineni, Hitomi Hosoya, Parveen Shiraz, Surbhi Sidana, Wen-Kai Weng, Vanessa E. Kennedy, Melody Smith, Saurabh Dahiya, Kara L. Davis, Sneha Ramakrishna, Liora Michal Schultz, Ramya Tunuguntla, Steven A. Feldman, Lori Muffly, Crystal L. Mackall, David B. Miklos, Matthew J. Frank
Journal: Blood
Blood (2024) 144 (Supplement 1): 2064.
https://doi.org/10.1182/blood-2024-198489
Published: 2024
Journal Articles

Safety and Efficacy of Chimeric Antigen Receptor T-Cell Therapy in Octogenarian Patients (Aged ≥ 80) with Relapsed or Refractory (R/R) Large B-Cell Lymphoma (LBCL)

Free
Dasom Lee, Sushma Bharadwaj, Masooma S Rana, Alexandria Jensen, William Wang, Nima Ghalehsari, Bita Sahaf, Jayasindhu Mallampet, Sarah Elkordy, Theresa Latchford, Sally Arai, Laura Johnston, Hitomi Hosoya, Robert Lowsky, Robert S. Negrin, Andrew R. Rezvani, Judith Shizuru, Everett H. Meyer, Parveen Shiraz, Lekha Mikkilineni, Wen-Kai Weng, Lauren S. Maeda, Melody Smith, Surbhi Sidana, Lori Muffly, Matthew J. Frank, David B. Miklos, Saurabh Dahiya
Journal: Blood
Blood (2024) 144 (Supplement 1): 386.
https://doi.org/10.1182/blood-2024-201822
Published: 2024
Journal Articles

Long Term Outcomes of a Randomized Trial of Anti-T Lymphocyte Globulin to Improve Moderate-Severe Chronic Gvhd Free Survival after Unrelated Donor Hematopoietic Cell Transplantation: A CIBMTR Analysis

Free
Robert J. Soiffer, Mitchell Horwitz, Joseph P. McGuirk, Sudhindra Rao, Peter Westervelt, John F. DiPersio, Laura Johnston, Jonathan Serody, Witold B Rybka, Paul Shaughnessy, Joseph A. Pidala, Vincent Ho, Andrew Artz, Madhuri Vusirikala, David L. Porter, Paul J. Martin, David Avigan, Michael R Bishop, Ran Reshef, Andrew Peterson, Kwang Wooahn, Adetola A. Kassim, Ryotaro Nakamura, Yi-Bin Chen, Linda Burns
Journal: Blood
Blood (2024) 144 (Supplement 1): 4911.
https://doi.org/10.1182/blood-2024-205572
Published: 2024
Journal Articles

A phase 1 clinical trial of NKTR-255 with CD19-22 CAR T-cell therapy for refractory B-cell acute lymphoblastic leukemia

Free
Clinical Trials & Observations
Hrishikesh Srinagesh, Clayton Jackson, Parveen Shiraz, Nikeshan Jeyakumar, Mark Hamilton, Emily Egeler, Sharon Mavroukakis, Adam Kuo, Juancarlos Cancilla, Bita Sahaf, Neha Agarwal, Alyssa Kanegai, Anne Marijn Kramer, Sally Arai, Sushma Bharadwaj, Saurabh Dahiya, Hitomi Hosoya, Laura Johnston, Vanessa Kennedy, Michaela Liedtke, Robert Lowsky, Lekha Mikkilineni, Robert Negrin, Andrew Rezvani, Surbhi Sidana, Judith Shizuru, Melody Smith, Wen-Kai Weng, Steven Feldman, Matthew J. Frank, Zachary Lee, Mary Tagliaferri, A. Mario Marcondes, David Miklos, Crystal Mackall, Lori Muffly
Journal: Blood
Blood (2024) 144 (16): 1689–1698.
https://doi.org/10.1182/blood.2024024952
Published: 2024
Includes: Supplemental data
Journal Articles

Phase 1 Trial Results for Patients with Advanced Hematologic Malignancies Undergoing Reduced Intensity Allogeneic HCT with Orca-T Donor Cell Therapy Product and Single Agent Tacrolimus

Free
Alejandro Villar-Prados, Everett H. Meyer, Katherine Sutherland, Robert S. Negrin, Sally Arai, Matthew J. Frank, Laura Johnston, Robert Lowsky, David B. Miklos, Lori S. Muffly, Saurabh Dahiya, Andrew R. Rezvani, Surbhi Sidana, Parveen Shiraz, Judith Shizuru, Wen-Kai Weng, Melody Smith, Sushma Bharadwaj, John Tamaresis, Anna Pavlova, Scott McClellan
Journal: Blood
Blood (2023) 142 (Supplement 1): 3560.
https://doi.org/10.1182/blood-2023-188162
Published: 2023
Journal Articles

The Composite Health Risk Assessment Model (CHARM) to Predict 1-Year Non-Relapse Mortality (NRM) Among Older Recipients of Allogeneic Transplantation: A Prospective BMT-CTN Study 1704

Free
Andrew Artz, Brent R. Logan, Wael Saber, Nancy Geller, Anna Bellach, Jianqun Kou, William Wood, John M. McCarty, Thomas G. Knight, Lyndsey Runaas, Laura Johnston, Jeremy Walston, Ryotaro Nakamura, Tammy Schuler, Asmita Mishra, Joseph Uberti, Parastoo B. Dahi, Jennifer N. Saultz, Shannon R McCurdy, Lawrence Morris, Philip Imus, William J. Hogan, Kalyan Nadiminti, Vijaya Raj Bhatt, Deborah Mattila, Bailey Protz, Steven M. Devine, Mary M. Horowitz, Mohamed Sorror
Journal: Blood
Blood (2023) 142 (Supplement 1): 109.
https://doi.org/10.1182/blood-2023-173855
Published: 2023
Journal Articles

Clofarabine and High-Dose Melphalan Reduced Intensity Conditioning Regimen with Methotrexate-Based GvHD Prophylaxis

Free
Sandy On, Walter Domingo, Edna Cheung, Laura Johnston
Journal: Blood
Blood (2023) 142 (Supplement 1): 6952.
https://doi.org/10.1182/blood-2023-182983
Published: 2023
Journal Articles

CAR19 Therapy Drives Expansion of Clonal Hematopoiesis and Associated Cytopenias

Free
Mark P. Hamilton, Brian J. Sworder, Stefan K. Alig, Zinaida Good, Jan Boegeholz, Joseph Schroers-Martin, John Tamaresis, Mohammad Shahrokh Esfahani, Ying Lu, Mari Olsen, Chih Long Liu, Zachary Ehlinger, Moksha Desai, Felicia Liu-Fei, Lori S. Muffly, Robert S. Negrin, Sally Arai, Laura Johnston, Robert Lowsky, Everett H. Meyer, Andrew R. Rezvani, Judith Shizuru, Wen-Kai Weng, Parveen Shiraz, Surbhi Sidana, Sushma Bharadwaj, Melody Smith, Saurabh Dahiya, Bita Sahaf, Maximilian Diehn, Matthew J. Frank, Crystal L. Mackall, David M. Kurtz, David B. Miklos, Ash A. Alizadeh
Journal: Blood
Blood (2023) 142 (Supplement 1): 360.
https://doi.org/10.1182/blood-2023-182522
Published: 2023
Journal Articles

CD22-directed CAR T-cell therapy induces complete remissions in CD19-directed CAR–refractory large B-cell lymphoma

Free
Clinical Trials & Observations Brief Report
John H. Baird, Matthew J. Frank, Juliana Craig, Shabnum Patel, Jay Y. Spiegel, Bita Sahaf, Jean S. Oak, Sheren F. Younes, Michael G. Ozawa, Eric Yang, Yasodha Natkunam, John Tamaresis, Zachary Ehlinger, Warren D. Reynolds, Sally Arai, Laura Johnston, Robert Lowsky, Everett Meyer, Robert S. Negrin, Andrew R. Rezvani, Parveen Shiraz, Surbhi Sidana, Wen-Kai Weng, Kara L. Davis, Sneha Ramakrishna, Liora Schultz, Chelsea Mullins, Allison Jacob, Ilan Kirsch, Steven A. Feldman, Crystal L. Mackall, David B. Miklos, Lori Muffly
Journal: Blood
Blood (2021) 137 (17): 2321–2325.
https://doi.org/10.1182/blood.2020009432
Published: 2021
Includes: Supplemental data
Journal Articles

Phase I Dose Escalation Study of Radiotherapy and Durvalumab (MEDI4736) in Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL): The RaDD Study

Free
Eliza A Hawkes, Kate Manos, Geoff Chong, Jodie Palmer, Michael MacManus, Colm Keane, MD, Andrew Scott, Jake Shortt, MBBS FRACP FRCPA PhD, David Ritchie, MD PhD, Leonid Churilov, Laura Johnston, Tom Witkowski, Allison Barraclough, Sze-Ting Lee, Wendi Lin, Rachel Koldej, Richard Khor
Journal: Blood
Blood (2019) 134 (Supplement_1): 5328.
https://doi.org/10.1182/blood-2019-122635
Published: 2019
Journal Articles

Consolidative CD8 + Memory T-Cell Donor Lymphocyte Infusion Augments Donor Chimerism with a Low Risk of Gvhd Following Matched Related Donor Hematopoietic Cell Transplantation

Free
Michael A. Spinner, MD, Lori S. Muffly, MD MS, Sally Arai, MD, Laura Johnston, MD, Everett H. Meyer, MD PhD, David B. Miklos, MD PhD, Robert S. Negrin, MD, Andrew R. Rezvani, MD, Judith A. Shizuru, MD PhD, Wen-Kai Weng, MD PhD, Samuel Strober, MD, Robert Lowsky, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2003.
https://doi.org/10.1182/blood.V130.Suppl_1.2003.2003
Published: 2017
Journal Articles

Posttransplant feasibility study of nilotinib prophylaxis for high-risk Philadelphia chromosome positive leukemia

Free
Clinical Trials & Observations
Paul A. Carpenter, Laura Johnston, Hugo F. Fernandez, Jerald P. Radich, Michael J. Mauro, Mary E. D. Flowers, Paul J. Martin, Theodore A. Gooley
Journal: Blood
Blood (2017) 130 (9): 1170–1172.
https://doi.org/10.1182/blood-2017-03-771121
Published: 2017
Includes: Supplemental data
Journal Articles

Allogeneic Transplants from HLA-Mismatched Unrelated Donors Using Total Lymphoid Irradiation and Antithymocyte Globulin Conditioning Retain a Low Risk of Graft-Versus-Host Disease and Non-Relapse Mortality with at Least As Potent Anti-Tumor Activity As with Matched Unrelated Donors

Free
Michael A. Spinner, MD, Marcelo Fernandez Vina, PhD, Linda Elder, BA, Sally Arai, MD, Laura Johnston, MD, Everett Meyer, MD PhD, David Miklos, MD PhD, Lori Muffly, MD, Robert S. Negrin, MD, Judith Shizuru, MD PhD, Wen-Kai Weng, MD PhD, Ginna G. Laport, MD, Samuel Strober, MD, Robert Lowsky, MD, Andrew R. Rezvani, MD
Journal: Blood
Blood (2016) 128 (22): 4669.
https://doi.org/10.1182/blood.V128.22.4669.4669
Published: 2016