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Journal Articles

Evading eviction: leukemic stem cell squatters

Daniela S. Krause

Blood (2021) 138 (12): 1007–1008.

https://doi.org/10.1182/blood.2021012623

Published: 2021

Journal Articles

How I treat pediatric acute myeloid leukemia

Jeffrey E. Rubnitz, Gertjan J. L. Kaspers

Blood (2021) 138 (12): 1009–1018.

https://doi.org/10.1182/blood.2021011694

Published: 2021

Journal Articles

Quantitative proteomics reveals specific metabolic features of acute myeloid leukemia stem cells

Blood (2020) 136 (13): 1507–1519.

https://doi.org/10.1182/blood.2019003654

Published: 2020

Includes: Supplemental data

Journal Articles

The miR-185/PAK6 axis predicts therapy response and regulates survival of drug-resistant leukemic stem cells in CML

Blood (2020) 136 (5): 596–609.

https://doi.org/10.1182/blood.2019003636

Published: 2020

Includes: Supplemental data

Journal Articles

Tudor Domain-Focused CRISPR Dropout Screen Identifies SGF29 As a Novel Essential Gene in MLL -Rearranged Leukemias

Anthony K. N. Chan, PhD, Christopher D. Delaney, Lu Yang, PhD, Wen-Han Chang, PhD, Kazuya Miyashita, PhD, Qiao Liu, MD, Sheela Pangeni Pokharel, MSc, Scott A. Armstrong, MD PhD, Chun-Wei David Chen, PhD

Blood (2019) 134 (Supplement_1): 530.

https://doi.org/10.1182/blood-2019-131467

Published: 2019

Journal Articles

Changes in the Main Bone Marrow Cell Subpopulations May Potentially Contribute to the Initiation of Acute Myeloid Leukemia

Shlomit Yehudai-Reshef, PhD, Rawan Sabah, Tal Gabay, Tsila Zuckerman, MD

Blood (2019) 134 (Supplement_1): 2494.

https://doi.org/10.1182/blood-2019-128097

Published: 2019

Journal Articles

CDK6 Antagonizes TP53-Induced Responses during Tumorigenesis

Veronika Sexl, MD PhD, Karoline Kollmann, PhD, Florian Bellutti

Blood (2019) 134 (Supplement_1): SCI-15.

https://doi.org/10.1182/blood-2019-121101

Published: 2019

Journal Articles

Brefeldin Α Reduces STAT3 Dependent Survival of Acute Leukemia and Neuroblastoma Cells

Mitsuteru Hiwatari, MD PhD, Kentaro Watanabe, MD, Yasuo Kubota, MD, Masahiro Sekiguchi, MD, Junko Takita, MD PhD

Blood (2019) 134 (Supplement_1): 5762.

https://doi.org/10.1182/blood-2019-130056

Published: 2019

Journal Articles

The Membrane Scaffold CD82 Regulates Acute Myeloid Leukemia Dormancy and Bone Marrow Niche Interactions

Muskan Floren, BS, Erica Pascetti, BS, Jennifer Gillette, PhD

Blood (2019) 134 (Supplement_1): 1396.

https://doi.org/10.1182/blood-2019-129320

Published: 2019

Journal Articles

Dasatinib Inhibits FLT3 /ITD and PTPN11 mutated Acute Myeloid Leukemia Cells Overexpressing SRC Tyrosine Kinases

Sigal Tavor, MD, Tali Shalit, PhD, Noa Chapal Ilani, PhD, Yoni Moskovitz, PhD, Nir Livnat, BSc, Yoram Groner, PhD, Haim Bar, PhD, Alexander Plotnikov, PhD, Nathali Kaushansky, PhD, Liran I. Shlush, MD

Blood (2019) 134 (Supplement_1): 1451.

https://doi.org/10.1182/blood-2019-128016

Published: 2019

Journal Articles

DNA Methylation-Based Classification Highlights the Role of the JAK-STAT Pathway in Acute Myeloid Leukemia

Brian Giacopelli, BS, Min Wang, Ada C Cleary, Yue-zhong Wu, MSc, Anna Reister Schultz, James S. Blachly, MD, Ann-Kathrin Eisfeld, MD, Kevin R Coombes, Clara D. Bloomfield, MD, Brian J. Druker, Jeffrey W. Tyner, John C. Byrd, MD, Christopher C. Oakes, PhD

Blood (2019) 134 (Supplement_1): 1413.

https://doi.org/10.1182/blood-2019-126212

Published: 2019

Journal Articles

Targeting WNT10B-Driven Signalling through Induction of FZD6 By Porcupine Inhibition in T Cell Acute Lymphoblastic Leukemia

Adriana Cassaro, PhD, Francesca Lazzaroni, Dr, Giovanni Grillo, MD, Gianluigi Reda, MD, Roberto Cairoli, MD, Alessandro Beghini

Blood (2019) 134 (Supplement_1): 3956.

https://doi.org/10.1182/blood-2019-124871

Published: 2019

Journal Articles

Transgenic Expression of IL15 in CD123-Specific BiTE-Secreting Engager T-Cells Results in Improved Anti-AML Activity

Hong Mu-Mosley, MD PhD, Lauren B Ostermann, Muharrem Muftuoglu, MD, Wendy Schober, Nalini B Patel, Abishek Vaidya, MS, Challice L. Bonifant, MD PhD, Stephen Gottschalk, MD, Mireya Paulina Velasquez, MD, Michael Andreeff, MD PhD

Blood (2019) 134 (Supplement_1): 3917.

https://doi.org/10.1182/blood-2019-125928

Published: 2019

Journal Articles

Inhibition of BMP-Smad Pathway Reduces Leukemic Stemness in Pediatric AML

Xin Long, PhD, Chris Man, PhD, Padmini Narayanan, PhD, Elizabeth Seashore, MD, Michele Redell, MD PhD

Blood (2019) 134 (Supplement_1): 3731.

https://doi.org/10.1182/blood-2019-129074

Published: 2019

Journal Articles

The Role of the BMP Pathway in Sustaining CML Stem Cells in the Bone Marrow Niche

Caroline Busch, BSc, MSc, Chloe Gulliver, BSc, MSc, Theresa Mulholland, BSc, Michele Zagnoni, BSc, MSc, PhD, Catherine C. Berry, BSc,PhD, Helen Wheadon, BSc, PhD

Blood (2019) 134 (Supplement_1): 3732.

https://doi.org/10.1182/blood-2019-123967

Published: 2019

Journal Articles

Efficient Elimination of Acute Myeloid Leukemia Cells through Inhibition of KDM4A in Combination with PARP Inhibition

Laura Monaghan, BSc, Matthew Edward Massett, MSc, BSc, Roderick P Bunschoten, BSc, Petrisor Alin Pirvan, MSc, BSc, Alex Hoose, Bsc, PhD, Taeju Park, BSc, Joana Bittencourt-Silvestre, BSc, MSc, Robert M J Liskamp, BSc, PhD, Heather G Jørgensen, Xu Huang, BSc, PhD

Blood (2019) 134 (Supplement_1): 3756.

https://doi.org/10.1182/blood-2019-125355

Published: 2019

Journal Articles

Leukemic Stem Cell Phenotype Is Associated with Mutational Profile in Acute Myeloid Leukemia

Ja Min Byun, MD, Dong-Yeop Shin, MD PhD, Youngil Koh, Sung-Soo Yoon, MD PhD, Junshik Hong, MD, Inho Kim, MD PhD

Blood (2019) 134 (Supplement_1): 3852.

https://doi.org/10.1182/blood-2019-126373

Published: 2019

Journal Articles

Characterization of Leukemic Stem Cells Heterogeneity in Chronic Myeloid Leukemia

Rebecca Warfvinge, MSc, Mikael Sommarin, Parashar Dhapola, MSc, Ulrich Pfisterer, PhD, Linda Geironson Ulfsson, PhD, Fatemeh Safi, MSc, Ram Krishna Thakur, PhD, Johan Richter, MD PhD, Göran Karlsson, PhD

Blood (2019) 134 (Supplement_1): 4140.

https://doi.org/10.1182/blood-2019-130956

Published: 2019

Journal Articles

SM09419, a Novel, Small-Molecule CDC-like Kinase (CLK) Inhibitor, Demonstrates Strong Inhibition of the Wnt Signaling Pathway and Antitumor Effects in Tumor Protein p53 (TP53)-Mutant Acute Myeloid Leukemia Models

Heekyung Chung, PhD, Emily Creger, Lauren Sitts, Kevin Chiu, Chi-Ching Mak, PhD, Sunil KC, PhD, Betty Tam, PhD, Gail Bucci, Josh Stewart, Timothy Phalen, PhD, Steven Cha, MD

Blood (2019) 134 (Supplement_1): 3913.

https://doi.org/10.1182/blood-2019-131209

Published: 2019

Journal Articles

Inhibition of the MiR-185-PAK6-Mediated Survival and Metabolic Pathways Selectively Targets Drug-Resistant CML Stem/Progenitor Cells

Andrew Wu, BSc, Katharina Rothe, PhD, Min Chen, PhD, Hanyang Lin, PhD, Artem Babaian, PhD, Ryan Yen, BSc, Donna L. Forrest, MD, Xiaoyan Jiang, MD PhD

Blood (2019) 134 (Supplement_1): 4138.

https://doi.org/10.1182/blood-2019-127826

Published: 2019

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Evading eviction: leukemic stem cell squatters

How I treat pediatric acute myeloid leukemia

Quantitative proteomics reveals specific metabolic features of acute myeloid leukemia stem cells

The miR-185/PAK6 axis predicts therapy response and regulates survival of drug-resistant leukemic stem cells in CML

Tudor Domain-Focused CRISPR Dropout Screen Identifies SGF29 As a Novel Essential Gene in MLL -Rearranged Leukemias

Changes in the Main Bone Marrow Cell Subpopulations May Potentially Contribute to the Initiation of Acute Myeloid Leukemia

CDK6 Antagonizes TP53-Induced Responses during Tumorigenesis

Brefeldin Α Reduces STAT3 Dependent Survival of Acute Leukemia and Neuroblastoma Cells

The Membrane Scaffold CD82 Regulates Acute Myeloid Leukemia Dormancy and Bone Marrow Niche Interactions

Dasatinib Inhibits FLT3 /ITD and PTPN11 mutated Acute Myeloid Leukemia Cells Overexpressing SRC Tyrosine Kinases

DNA Methylation-Based Classification Highlights the Role of the JAK-STAT Pathway in Acute Myeloid Leukemia

Targeting WNT10B-Driven Signalling through Induction of FZD6 By Porcupine Inhibition in T Cell Acute Lymphoblastic Leukemia

Transgenic Expression of IL15 in CD123-Specific BiTE-Secreting Engager T-Cells Results in Improved Anti-AML Activity

Inhibition of BMP-Smad Pathway Reduces Leukemic Stemness in Pediatric AML

The Role of the BMP Pathway in Sustaining CML Stem Cells in the Bone Marrow Niche

Efficient Elimination of Acute Myeloid Leukemia Cells through Inhibition of KDM4A in Combination with PARP Inhibition

Leukemic Stem Cell Phenotype Is Associated with Mutational Profile in Acute Myeloid Leukemia

Characterization of Leukemic Stem Cells Heterogeneity in Chronic Myeloid Leukemia

SM09419, a Novel, Small-Molecule CDC-like Kinase (CLK) Inhibitor, Demonstrates Strong Inhibition of the Wnt Signaling Pathway and Antitumor Effects in Tumor Protein p53 (TP53)-Mutant Acute Myeloid Leukemia Models

Inhibition of the MiR-185-PAK6-Mediated Survival and Metabolic Pathways Selectively Targets Drug-Resistant CML Stem/Progenitor Cells

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