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Journal Articles

Using the binary language of IL-2 to prevent GVHD

Free
Everett H. Meyer
Journal: Blood
Blood (2021) 137 (16): 2136–2137.
https://doi.org/10.1182/blood.2021010836
Published: 2021
Journal Articles

Treg sensitivity to FasL and relative IL-2 deprivation drive idiopathic aplastic anemia immune dysfunction

Free
Shok Ping Lim, Benedetta Costantini, Syed A. Mian, Pilar Perez Abellan, Shreyans Gandhi, Marc Martinez Llordella, Juan Jose Lozano, Rita Antunes dos Reis, Giovanni A. M. Povoleri, Thanos P. Mourikis, Ander Abarrategi, Linda Ariza-McNaughton, Susanne Heck, Jonathan M. Irish, Giovanna Lombardi, Judith C. W. Marsh, Dominique Bonnet, Shahram Kordasti, Ghulam J. Mufti
Journal: Blood
Blood (2020) 136 (7): 885–897.
https://doi.org/10.1182/blood.2019001347
Published: 2020
Includes: Supplemental data
Journal Articles

Ruxolitinib Reverses Checkpoint Inhibition By Downregulating PD-L1 and PD-L2 Expression on Both Tumor and Stromal Cells in Multiple Myeloma

Free
Haiming Chen, MD PhD, Mingjie Li, BS, Eric Sanchez, BA, Nicole Ng, BS, Erin Yu, BS, Sean Bujarski, BA, Zhengyi Yin, Tara Hekmati, Dylan Field, Jasper Wang, Isabella Nassir, Janna Yu, Justin Huang, David Daniely, Cathy S. Wang, BS, Ning Xu, PhD, James R. Berenson, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4402.
https://doi.org/10.1182/blood-2019-130888
Published: 2019
Journal Articles

A Failure to Start: Aborted Activation of CAR T Cells in Chronic Lymphocytic Leukemia

Free
McKensie Collins, BS, Weimin Kong, PhD, Inyoung Jung, BS, Meng Wang, BS, Stefan M Lundh, BS, Carl H June, MD, J. Joseph Melenhorst, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 681.
https://doi.org/10.1182/blood-2019-122063
Published: 2019
Journal Articles

IL-21-Expanded Natural Killer Cells As Autologous Cell Therapy for CLL

Free
Max Yano, Jennie Rachel Lance, Xiaokui Mo, PhD MAS, Dean Anthony Lee, MD PhD, Natarajan Muthusamy, DVM,PhD, John C. Byrd, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4302.
https://doi.org/10.1182/blood-2019-127620
Published: 2019
Journal Articles

IL-21-Expanded NK Cells As Autologous Cell Therapy for CLL

Free
Jennie Rachel Lance, Max Yano, Xiaokui Mo, PhD MAS, Dean Anthony Lee, MD PhD, Natarajan Muthusamy, DVM,PhD, John C. Byrd, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4303.
https://doi.org/10.1182/blood-2019-131034
Published: 2019
Journal Articles

Diffuse Large B-Cell Lymphoma Is Infiltrated with Functional CD8 + T-Cells Lacking the Hallmarks of Exhaustion

Free
Adam Greenbaum, MD PhD, Ajay K. Gopal, MD, Jonathan R. Fromm, MD PhD, A McGarry Houghton, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1518.
https://doi.org/10.1182/blood-2019-126217
Published: 2019
Journal Articles

Engineering High Affinity and Cleavage Resistant CD16 to Augment ADCC of Placental Hematopoietic Stem Cells-Derived Natural Killer Cells

Free
Xuan Guo, PhD, Srinivas Somanchi, PhD, Rohit Mathur, PhD, Shuyang He, PhD, Qian Ye, PhD, Andrea Difiglia, BS, Salvatore Rotondo, MS, Hemlata Rana, MS, Weifang Ling, PhD, James Edinger, PhD, Robert Hariri, MD PhD, Xiaokui Zhang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1576.
https://doi.org/10.1182/blood-2019-127009
Published: 2019
Journal Articles

NLRP6 in Donor T Cells Separately Regulates CD4 and CD8 Mediated Graft-Versus-Host Disease in Experimental Murine BMT

Free
Masahiro Suto, Eri Matsuki, MD, Erika Sekiguchi, Hiroya Tamaki, MD PhD, Isao Tawara, MD PhD, Grace Chen, MD PhD, Kenichi Ishizawa, MD PhD, Pavan Reddy, Tomomi Toubai
Journal: Blood
Blood (2019) 134 (Supplement_1): 1926.
https://doi.org/10.1182/blood-2019-123875
Published: 2019
Journal Articles

PD-L1 Checkpoint Blockade Augments Anti-Tumor Immune Response of GD2 or HER2-Bsab Ex Vivo Armed T-Cells (EVAT) Therapy in Osteosarcoma

Free
Jeong A Park, MD PhD, Hong fen Guo, PhD, Hong Xu, PhD, Nai-Kong V. Cheung, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1959.
https://doi.org/10.1182/blood-2019-131325
Published: 2019
Journal Articles

Functional Characterization of Gamma Delta T Cells and Allogeneic Activated NK Cells As Effector Cells for Tafasitamab (MOR208)

Free
Jung Hyun Her, Dominik Pretscher, Sungyoo Cho, Yu-Kyeong Hwang, Timm Hoeres, Rainer Boxhammer, Stefan Steidl, Maria Patra, Juergen Schanzer, Jan Endell
Journal: Blood
Blood (2019) 134 (Supplement_1): 3801.
https://doi.org/10.1182/blood-2019-128511
Published: 2019
Journal Articles

Transcriptome Sequencing Demonstrates Unique Signature Associated with Durable Clinical Response to DC/AML Fusion Vaccine

Free
Jessica Liegel, MD, Manoj Bhasin, PhD, German A. Pihan, MD, Dina Stroopinsky, PhD, Beena Thomas, PhD, Shreya Sindhu, Haider Ghiasuddin, Emma Logan, Adam Morin, Marzia Capelletti, PhD MMSc, Shira Orr, PhD, Myrna Nahas, MD, Matthew Weinstock, MD, Maryam Rahimian, MD, Lina Bisharat, Shufen Meng, MD, Richard M. Stone, MD, Donald Kufe, MD, David E. Avigan, MD, Jacalyn Rosenblatt, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3832.
https://doi.org/10.1182/blood-2019-129451
Published: 2019
Journal Articles

Combined Thalidomide and Recombinant Human Interferon-α-1b and Interleukin-2 for Acute Myeloid Leukemia of Various Disease Status: A Multi-Center Prospective Study

Free
Ruihua Mi, Lin Chen, MD, Xudong Wei, PhD, Xiaojiao WANG, Yongping Song, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3865.
https://doi.org/10.1182/blood-2019-128431
Published: 2019
Journal Articles

TNB-486, a Novel Fully Human Bispecific CD19 x CD3 Antibody That Kills CD19-Positive Tumor Cells with Minimal Cytokine Secretion

Free
Harbani Malik, PhD, Ben Buelow, MD PhD, Udaya Rangaswamy, PhD, Aarti Balasubramani, Andrew Boudreau, Kevin Dang, Laura Davison, PhD, Shelley Force Aldred, Katherine Marie Harris, MD, Suhasini Iyer, PhD, Brett Jorgensen, PhD, Duy Pham, MBA, Kirthana Prabhakar, Ute Schellenberger, PhD, Harshad Ugamraj, Nathan Trinklein, PhD, Wim Van Schooten, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4070.
https://doi.org/10.1182/blood-2019-123226
Published: 2019
Journal Articles

A Phase I Study of Nivolumab and Lenalidomide in Relapsed/ Refractory B Cell Lymphoma

Free
David A. Bond, MD, Vedat Yildiz, Lai Wei, PhD, Lapo Alinari, MD PhD, Basem M. William, MRCP,MD, Jonathan E. Brammer, MD, Beth A. Christian, MD, Kristie A. Blum, MD, Kami J. Maddocks, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4091.
https://doi.org/10.1182/blood-2019-130539
Published: 2019
Journal Articles

Phase 2 Study of E7777, a Diphtheria Toxin Fragment-Interleukin-2 Fusion Protein, in Japanese Patients with Relapsed or Refractory Peripheral and Cutaneous T-Cell Lymphoma

Free
Dai Maruyama, MD PhD, Kiyoshi Ando, Kazuhito Yamamoto, Eiji Kiyohara, MD, Yasuhito Terui, MD PhD, Noriko Fukuhara, MD PhD, Tomomitsu Miyagaki, MD PhD, Hidetsugu Kawai, MD, Yoshiki Tokura, MD PhD, Mamiko Sakata-Yanagimoto, MD PhD, Tadahiko Igarashi, MD PhD, Junya Kuroda, MD PhD, Jiro Fujita, MD PhD, Toshiki Uchida, MD PhD, Takayuki Ishikawa, MD PhD, Kentaro Yonekura, MD PhD, Koji Kato, MD PhD, Tadashi Nakanishi, Kenya Nakai, Risa Matsunaga, Kensei Tobinai, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4032.
https://doi.org/10.1182/blood-2019-121723
Published: 2019
Journal Articles

The Combination of Dexamethasone and Ruxolitinib Synergistically Attenuates Disease Manifestations in a Preclinical Model of Hemophagocytic Lymphohistiocytosis

Free
Lauren K. Meyer, Katherine Verbist, PhD, Sabrin Albeituni, PhD, Rachel Bassett, Michelle L. Hermiston, MD PhD, Kim E. Nichols, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 81.
https://doi.org/10.1182/blood-2019-129112
Published: 2019
Journal Articles

Immune Monitoring of CD34+ Placental Cell Derived Natural Killer Cell Therapy (PNK-007) in Phase I Study of Multiple Myeloma

Free
William Van Der Touw, Lin Kang, PhD, Joseph Dennis Tario, PhD, Bhavani Stout, Vanessa Voskinarian-Berse, Valentina Rousseva, Paul K. Wallace, MS, PhD, Robert Hariri, MD PhD, Xiaokui Zhang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4457.
https://doi.org/10.1182/blood-2019-124509
Published: 2019
Journal Articles

Syndecan-1 Is Critical in ARF6-Dependent Macropinocytosis Driven By KRAS Mutation in the Pathophysiology of Multiple Myeloma

Free
Tengteng Yu, MD PhD, Liang Lin, PhD, Kenneth Wen, Lijie Xing, MD, Jiye Liu, PhD, Shih-Feng Cho, MD PhD, Phillip Hsieh, Ola Rizq, MD PhD, Yuyin Li, PhD, Liang Yu, Xiang Wu, Eugenio Morelli, MD, Yan Xu, MD, Gang An, MD, Nikhil C. Munshi, MD, Lugui Qiu, MD PhD, Kenneth C. Anderson, MD, Yu-Tzu Tai, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4371.
https://doi.org/10.1182/blood-2019-127454
Published: 2019
Journal Articles

Neddylation Pathway Regulates Treg Differentiation and T Cell Function in Chronic Lymphocytic Leukemia (CLL) Ex Vivo and Murine In Vivo Studies

Free
Scott R Best, BS, Vi Lam, Nur Bruss, BS, Taylor Hashiguchi Rowland, BS, Adam S. Kittai, MD, Tingting Liu, Allison J Berger, PhD, Alexey Danilov, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4313.
https://doi.org/10.1182/blood-2019-123600
Published: 2019