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Yunchao Chang
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Journal Articles

Differential Role of Crebbp Missense and Truncating Mutations in the Malignant Transformation of Germinal Center B Cells

Free
Chuanjiang Yu, Mara Holloman, Andrew Kim, Yunchao Chang, Antony Holmes, Bowen Cai, Stefanie N Meyer, Katia Basso, Govind Bhagat, Riccardo Dalla-Favera, Charles G. Mullighan, Laura Pasqualucci
Journal: Blood
Blood (2024) 144 (Supplement 1): 47.
https://doi.org/10.1182/blood-2024-208876
Published: 2024
Journal Articles

Revolutionizing B-ALL Cell Line Development: Novel Generation to Uncover Therapeutic Vulnerabilities

Free
Yiming Wu, Katarzyna Szoltysek, Tony Brown, Emily Backhaus, Tanya Khan, Qingsong Gao, Amanda Brewer, Yunchao Chang, Kathryn G. Roberts, Kristine R Crews, Ilaria Iacobucci, Ruth Wang'ondu, Charles G. Mullighan
Journal: Blood
Blood (2024) 144 (Supplement 1): 5829.
https://doi.org/10.1182/blood-2024-210486
Published: 2024
Journal Articles

STAG2/LMO2 Gamma-Delta (γδ) T-ALL: Identification and Characterization of an Extremely High Risk Group of T-ALL in the Very Young

Free
Shunsuke Kimura, Petri Pölönen, Lindsey Montefiori, Kenneth Caldwell, Ilaria Iacobucci, Chelsey Chen, Anthony Brown, Katie Han, Yen-Chun Liu, Yunchao Chang, Zhongshan Cheng, Zhou Yinmei, Chun Shik Park, Sharnise Mitchell, Noemi Reyes, Allen Yeoh, Andishe Attarbaschi, Andrew Moore, Atsushi Manabe, Barbara Buldini, Kean Hui Chiew, Chi Kong Li, Ching-Hon Pui, Chunxu Qu, Daisuke Tomizawa, Elisabeth Paietta, Franco Locatelli, Gabriele Escherich, Gao Qingsong, Hannah Elisa Muhle, Hanne Vibeke Marquart, Hester A. de Groot-Kruseman, Jacob M. Rowe, Jan Stary, Jan Trka, John Kim Choi, Jules P.P. Meijerink, Junko Takita, Katarzyna Pawinska-Wasikowska, Kjeld Schmiegelow, Mariko Eguchi, Martin Schrappe, Martin Zimmermann, Masatoshi Takagi, Melissa Maybury, Michael Svaton, Michaela Reiterova, Michal Kicinski, Motohiro Kato, Orietta Spinelli, Pauline Mazilier, Paul G. Thomas, Riccardo Masetti, Rishi Sury Kotecha, Rob Pieters, Sarah Elitzur, Selina M Luger, Shuhong Shen, Sima Jeha, Steven M. Kornblau, Szymon Skoczen, Takako Miyamura, Tiffaney Vincent, Toshihiko Imamura, Valentino Conter, Yanjing Tang, Zhaohui Gu, Kathryn G. Roberts, David T. Teachey, Kristine R Crews, Cheng Cheng, Jun J. Yang, Hiroto Inaba, Charles G. Mullighan
Journal: Blood
Blood (2023) 142 (Supplement 1): 845.
https://doi.org/10.1182/blood-2023-178688
Published: 2023
Journal Articles

The orally bioavailable GSPT1/2 degrader SJ6986 exhibits in vivo efficacy in acute lymphoblastic leukemia

Free
Yunchao Chang, Fatemeh Keramatnia, Pankaj S. Ghate, Gisele Nishiguchi, Qingsong Gao, Ilaria Iacobucci, Lei Yang, Divyabharathi Chepyala, Ashutosh Mishra, Anthony A. High, Hiroaki Goto, Koshi Akahane, Junmin Peng, Jun J. Yang, Marcus Fischer, Zoran Rankovic, Charles G. Mullighan
Journal: Blood
Blood (2023) 142 (7): 629–642.
https://doi.org/10.1182/blood.2022017813
Published: 2023
Includes: Supplemental data
Journal Articles

Comprehensive Genome Characterization of Childhood T-ALL Links Oncogene Activation Mechanism and Subtypes to Prognosis

Free
Petri Pölönen, Abdelrahman Elsayed, Danika Di Giacomo, Lindsey Montefiori, Shunsuke Kimura, Jason Myers, Dale Hedges, Jason Xu, Yawei Hui, Zhongshan Cheng, Yiping Fan, Ilaria Iacobucci, Yunchao Chang, Rawan Shraim, Meenakshi Devidas, Stuart S. Winter, Kimberly P. Dunsmore, Jun J.J. Yang, Tiffaney L. Vincent, Kai Tan, Changya Chen, Haley Newman, Mignon L. Loh, Elizabeth A. Raetz, Stephen P. Hunger, Evadnie Rampersaud, Ti-Cheng Chang, Gang Wu, Stanley B. Pounds, Charles G. Mullighan, David T. Teachey
Journal: Blood
Blood (2022) 140 (Supplement 1): 1727–1729.
https://doi.org/10.1182/blood-2022-167157
Published: 2022
Journal Articles

Degradation of Janus kinases in CRLF2 -rearranged acute lymphoblastic leukemia

Free
Yunchao Chang, Jaeki Min, Jamie A. Jarusiewicz, Marisa Actis, Shanshan Yu-Chen Bradford, Anand Mayasundari, Lei Yang, Divyabharathi Chepyala, Lisa J. Alcock, Kathryn G. Roberts, Stanley Nithianantham, Dylan Maxwell, Lauren Rowland, Randolph Larsen, Aman Seth, Hiroaki Goto, Toshihiko Imamura, Koshi Akahane, Baranda S. Hansen, Shondra M. Pruett-Miller, Elisabeth M. Paietta, Mark R. Litzow, Chunxu Qu, Jun J. Yang, Marcus Fischer, Zoran Rankovic, Charles G. Mullighan
Journal: Blood
Blood (2021) 138 (23): 2313–2326.
https://doi.org/10.1182/blood.2020006846
Published: 2021
Includes: Supplemental data
Journal Articles

CREBBP Histone Acetyltransferase Domain Mutations Result in Dexamethasone Resistance in B-Progenitor Acute Lymphoblastic Leukemia

Free
Yunchao Chang, PhD, David W. Woessner, PhD MS, Wenwei Lin, PhD, Taosheng Chen, PhD, Beisi Xu, PhD, Yiping Fan, PhD, Haiyan Tan, PhD, Junmin Peng, PhD, Lawryn Kasper, PhD, Michelle L. Churchman, PhD, Mignon L. Loh, MD, Stephen P. Hunger, MD, Aman Seth, PhD, Karen Gascoigne, PhD, Paul K Brindle, PhD, Charles G. Mullighan, MBBS, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 560.
https://doi.org/10.1182/blood.V130.Suppl_1.560.560
Published: 2017
Journal Articles

Pleiotrophin produced by multiple myeloma induces transdifferentiation of monocytes into vascular endothelial cells: a novel mechanism of tumor-induced vasculogenesis

Free
Haiming Chen, Richard A. Campbell, Yunchao Chang, Mingjie Li, Cathy S. Wang, Jennifer Li, Eric Sanchez, Michael Share, Jeffrey Steinberg, Ariana Berenson, Dror Shalitin, Zhaohui Zeng, Dorina Gui, Pablo Perez-Pinera, Ronald J. Berenson, Jonathan Said, Benjamin Bonavida, Thomas F. Deuel, James R. Berenson
Journal: Blood
Blood (2009) 113 (9): 1992–2002.
https://doi.org/10.1182/blood-2008-02-133751
Published: 2009
Journal Articles

Zoledronic Acid Suppresses Vasculogenesis: A New Effect of Bisphosphonates.

Free
Haiming Chen, MD, PhD, Cathy S. Wang, Jennifer Li, Richard A. Campbell, Mingjie Li, Eric Sanchez, Jeffrey Steinberg, Michael Share, Dror Shalitin, PhD, James Wang, Shi-Jason Xie, Yunchao Chang, MD, Benjamin Bonavida, PhD, Thomas F. Deuel, MD, James R. Berenson, MD
Journal: Blood
Blood (2007) 110 (11): 3913.
https://doi.org/10.1182/blood.V110.11.3913.3913
Published: 2007
Journal Articles

Wnt/β-Catenin Signaling Is Essential for the Transdifferentiation of Monocytes into Endothelial Cells by mCSF and Pleiotrophin.

Free
Haiming Chen, MD, PhD, Mingjie Li, Richard Campbell, Cathy S. Wang, Jennifer Li, Eric Sanchez, Jeffrey Steinberg, Michael Share, Dror Shalitin, PhD, James Wang, Shi-Jason Xie, Yunchao Chang, PhD, Benjamin Bonavida, PhD, Thomas F. Deuel, MD, James R. Berenson, MD
Journal: Blood
Blood (2007) 110 (11): 1512.
https://doi.org/10.1182/blood.V110.11.1512.1512
Published: 2007
Journal Articles

Pleiotrophin is highly expressed by myeloma cells and promotes myeloma tumor growth

Free
Haiming Chen, Melinda S. Gordon, Richard A. Campbell, Mingjie Li, Cathy S. Wang, Hee Jin Lee, Eric Sanchez, Steven J. Manyak, Dorina Gui, Dror Shalitin, Jonathan Said, Yunchao Chang, Thomas F. Deuel, Stavroula Baritaki, Benjamin Bonavida, James R. Berenson
Journal: Blood
Blood (2007) 110 (1): 287–295.
https://doi.org/10.1182/blood-2006-08-042374
Published: 2007
Journal Articles

Pleiotrophin Secreted from Human Breast Cancer MCF-7-Ptn Cells Activates Stromal Fibroblasts, Induces Epithelial Island Formation, and Remodels the Microenvironment.

Free
Masahiko Zuka, MD, PhD, Yunchao Chang, Ph. D., Zhaoyi Wang, Ph. D., James R. Berenson, M.D., Thomas F. Deuel, MD
Journal: Blood
Blood (2006) 108 (11): 2568.
https://doi.org/10.1182/blood.V108.11.2568.2568
Published: 2006