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Journal Articles

Megakaryocytes and platelets from a novel human adipose tissue–derived mesenchymal stem cell line

Keiichi Tozawa, Yukako Ono-Uruga, Masaki Yazawa, Taisuke Mori, Mitsuru Murata, Shinichiro Okamoto, Yasuo Ikeda, Yumiko Matsubara

Blood (2019) 133 (7): 633–643.

https://doi.org/10.1182/blood-2018-04-842641

Published: 2019

Includes: Supplemental data

Journal Articles

Manufacture of Platelets from Human Adipose Tissue-Derived Mesenchymal Stromal/Stem Cells: Functional Comparison to Concentrate Platelets

Keiichi Tozawa, MD, Yukako Ono-Uruga, MD PhD, Masaki Yazawa, MD PhD, Taisuke Mori, PhD, Noriko Takizawa, Mitsuru Murata, MD PhD, Shinichiro Okamoto, MD PhD, Yasuo Ikeda, MD PhD, Yumiko Matsubara, PhD

Blood (2016) 128 (22): 1028.

https://doi.org/10.1182/blood.V128.22.1028.1028

Published: 2016

Journal Articles

Establishment of Human Adipose Tissue-Derived Stromal Cell Lines: A Culture System to Manufacture Megakaryocytes Releasing Functional Platelets

Keiichi Tozawa, MD, Yukako Ono-Uruga, MD PhD, Noriko Takizawa, Tadashi Horiuchi, Shin-ichiro Okamoto, MD PhD, Mitsuru Murata, MD PhD, Yasuo Ikeda, MD PhD, Yumiko Matsubara, PhD

Blood (2015) 126 (23): 656.

https://doi.org/10.1182/blood.V126.23.656.656

Published: 2015

Journal Articles

A Novel Mechanism of Megakaryopoiesis from Pre-Adipocytes: Involvement of Transferrin/ CD71/ TPO Pathways

Yukako Ono-Uruga, Keiichi Tozawa, MD, Sahoko Matsuoka, MD PhD, Tadashi Horiuchi, PhD, Shinichiro Okamoto, MD PhD, Mitsuru Murata, MD PhD, Yasuo Ikeda, MD PhD, Toshio Suda, MD PhD, Yumiko Matsubara, PhD

Blood (2014) 124 (21): 4306.

https://doi.org/10.1182/blood.V124.21.4306.4306

Published: 2014

Journal Articles

Subcutaneous Preadipocytes Are Ideal Candidate To Produce A Large Number Of Functional Platelets In a Culture System

Yukako Ono-Uruga, MD, PhD, Tatsuya Tanaka, Atsuko Igari, Takanori Moriki, MD, PhD, Kenji Yokoyama, MD, PhD, Takeru Zama, MD, PhD, Tadashi Horiuchi, PhD, Mitsuru Murata, MD, PhD, Yasuo Ikeda, MD, PhD, Toshio Suda, MD, PhD, Yumiko Matsubara, PhD

Blood (2013) 122 (21): 3271.

https://doi.org/10.1182/blood.V122.21.3271.3271

Published: 2013

Journal Articles

No more sugar-coating it: mucins and platelet biology

Yumiko Matsubara

Blood (2013) 122 (9): 1537–1538.

https://doi.org/10.1182/blood-2013-07-510974

Published: 2013

Journal Articles

Characterization of a Microchip Flow-Chamber System for the Analysis of Platelet Thrombus Formation Using Whole Blood Samples - Studies On Healthy Subjects

Yusuke Yamaguchi, Takanori Moriki, MD, PhD, Atsuko Igari, Yumiko Matsubara, PhD, Tomoko Ohnishi, Kazuya Hosokawa, PhD, Mitsuru Murata, MD, PhD

Blood (2012) 120 (21): 1144.

https://doi.org/10.1182/blood.V120.21.1144.1144

Published: 2012

Journal Articles

Pre-Adipocytes Differentiate Into Megakaryocytes (MK) by a Paracrine Thrombopoietin (TPO) Loop

Yukako Ono, MD, Yumiko Matsubara, PhD, Tatsuya Tanaka, Shinichiro Okamoto, MD, PhD, Yasuo Ikeda, MD, Mitsuru Murata, MD, PhD

Blood (2012) 120 (21): 4742.

https://doi.org/10.1182/blood.V120.21.4742.4742

Published: 2012

Journal Articles

Induction of functional platelets from mouse and human fibroblasts by p45NF-E2/Maf

Yukako Ono, Yuhuan Wang, Hidenori Suzuki, Shinichiro Okamoto, Yasuo Ikeda, Mitsuru Murata, Mortimer Poncz, Yumiko Matsubara

Blood (2012) 120 (18): 3812–3821.

https://doi.org/10.1182/blood-2012-02-413617

Published: 2012

Includes: Supplemental data

Journal Articles

A Meg by any other name

Yumiko Matsubara

Blood (2012) 120 (10): 1970–1971.

https://doi.org/10.1182/blood-2012-07-439174

Published: 2012

Journal Articles

Induction of Megakaryocytes From Fibroblasts by p45NF-E2/Maf

Yuhuan Wang, PhD, Yukako Ono, MD, Yasuo Ikeda, MD, Shinichiro Okamoto, MD, PhD, Mitsuru Murata, MD, Mortimer Poncz, MD, Yumiko Matsubara, PhD

Blood (2011) 118 (21): 908.

https://doi.org/10.1182/blood.V118.21.908.908

Published: 2011

Journal Articles

Megakaryocytes and Functional Platelets Obtained from Human Subcutaneous Adipocytes in an In Vitro Differentiation System.

Emi Saito, Yumiko Matsubara, PhD, Hidenori Suzuki, PhD, Yasuo Ikeda, MD, Mitsuru Murata, MD

Blood (2007) 110 (11): 3702.

https://doi.org/10.1182/blood.V110.11.3702.3702

Published: 2007

Journal Articles

GSK-3β Negatively Regulates Megakaryocyte and Platelet Production in an In Vitro Human Bone Marrow Mononuclear Cell-Derived Differentiation System.

Yumiko Matsubara, PhD, Mitsuru Murata, MD, Hidenori Suzuki, PhD, Kenji Yokoyama, MD, Hiroaki Ishihara, PhD, Yoshiyuki Morishima, PhD, Toshiro Shibano, PhD, Yasuo Ikeda, MD

Blood (2007) 110 (11): 4036.

https://doi.org/10.1182/blood.V110.11.4036.4036

Published: 2007

Journal Articles

The Genotype Combination of the P2Y12 Gene Might Confer Greater Risk for Coronary Artery Disease.

Koji Isobe, Yumiko Matsubara, PhD, Shinichi Takahashi, Toshihiro Uchida, Hiroaki Ishihara, PhD, Toshiro Shibano, PhD, Mie Ishikawa, MD, Kenichi Matsushita, MD, Shiro Iwanaga, MD, Satosh Ogawa, MD, Gentaro Watanabe, MD, Yasuo Ikeda, MD PhD, Mitsuru Murata, MD PhD

Blood (2006) 108 (11): 1468.

https://doi.org/10.1182/blood.V108.11.1468.1468

Published: 2006

Journal Articles

Enhancing Effect of Collagen Receptor Polymorphisms on In Vitro Platelet Reactivity to Aspirin in Healthy Subjects.

Miho Ushida, Yumiko Matsubara, PhD, Shinichi Takahashi, Hiroaki Ishihara, PhD, Toshiro Shibano, PhD, Gentaro Watanabe, MD, Yasuo Ikeda, MD, Mitsuru Murata, MD

Blood (2006) 108 (11): 1099.

https://doi.org/10.1182/blood.V108.11.1099.1099

Published: 2006

Journal Articles

Identification of ADRA2A Polymorphisms Related to Shear-Mediated Platelet Function by the PFA-100® System.

Mariko Yabe, MD, Yumiko Matsubara, PhD, Shinichi Takahashi, Hiroaki Ishihara, PhD, Toshiro Shibano, PhD, Koichi Miyaki, MD, Kazuyuki Omae, MD, Gentaro Watanabe, MD, Mitsuru Murata, MD, Yasuo Ikeda, MD

Blood (2006) 108 (11): 3913.

https://doi.org/10.1182/blood.V108.11.3913.3913

Published: 2006

Journal Articles

The Genotypic Combination of Homozygous Carriers of Both H1 Haplotype and 34C Shows a Significantly Lower Responsiveness to ADP-Induced Platelet Aggregation Than Others in Healthy Volunteers.

Koji Isobe, Yumiko Matsubara, MD, Shinichi Takahashi, Miho Iwashita, Risa Komine, Aya Shimizu, Toshihiro Uchida, Hiroaki Ishihara, PhD, Toshiro Shibano, PhD, Gentaro Watanabe, MD, Yasuo Ikeda, MD, Mitsuru Murata, MD

Blood (2005) 106 (11): 3560.

https://doi.org/10.1182/blood.V106.11.3560.3560

Published: 2005

Journal Articles

Ultrastructural Evidences of Caspase-Dependent Platelet Generation in ES Cell-Differentiation System.

Yumiko Matsubara, PhD, Mitsuru Murata, MD, Hidenori Suzuki, MD, Tamihiro Kamata, MD, Aya Shimizu, Andrew D. Leavitt, MD, Yasuo Ikeda, MD

Blood (2005) 106 (11): 3621.

https://doi.org/10.1182/blood.V106.11.3621.3621

Published: 2005

Journal Articles

Identification of novel mutations in ADAMTS13 in an adult patient with congenital thrombotic thrombocytopenic purpura

Toshihiro Uchida, Hideo Wada, Minoru Mizutani, Miho Iwashita, Hiroaki Ishihara, Toshiro Shibano, Misako Suzuki, Yumiko Matsubara, Kenji Soejima, Masanori Matsumoto, Yoshihiro Fujimura, Yasuo Ikeda, Mitsuru Murata, for The Research Project on Genetics of Thrombosis

Blood (2004) 104 (7): 2081–2083.

https://doi.org/10.1182/blood-2004-02-0715

Published: 2004

Journal Articles

Functional phenotype of phosphoinositide 3-kinase p85α-null platelets characterized by an impaired response to GP VI stimulation

Naohide Watanabe, Hideaki Nakajima, Hidenori Suzuki, Atsushi Oda, Yumiko Matsubara, Masaaki Moroi, Yasuo Terauchi, Takashi Kadowaki, Harumi Suzuki, Shigeo Koyasu, Yasuo Ikeda, Makoto Handa

Blood (2003) 102 (2): 541–548.

https://doi.org/10.1182/blood-2002-11-3327

Published: 2003

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Megakaryocytes and platelets from a novel human adipose tissue–derived mesenchymal stem cell line

Manufacture of Platelets from Human Adipose Tissue-Derived Mesenchymal Stromal/Stem Cells: Functional Comparison to Concentrate Platelets

Establishment of Human Adipose Tissue-Derived Stromal Cell Lines: A Culture System to Manufacture Megakaryocytes Releasing Functional Platelets

A Novel Mechanism of Megakaryopoiesis from Pre-Adipocytes: Involvement of Transferrin/ CD71/ TPO Pathways

Subcutaneous Preadipocytes Are Ideal Candidate To Produce A Large Number Of Functional Platelets In a Culture System

No more sugar-coating it: mucins and platelet biology

Characterization of a Microchip Flow-Chamber System for the Analysis of Platelet Thrombus Formation Using Whole Blood Samples - Studies On Healthy Subjects

Pre-Adipocytes Differentiate Into Megakaryocytes (MK) by a Paracrine Thrombopoietin (TPO) Loop

Induction of functional platelets from mouse and human fibroblasts by p45NF-E2/Maf

A Meg by any other name

Induction of Megakaryocytes From Fibroblasts by p45NF-E2/Maf

Megakaryocytes and Functional Platelets Obtained from Human Subcutaneous Adipocytes in an In Vitro Differentiation System.

GSK-3β Negatively Regulates Megakaryocyte and Platelet Production in an In Vitro Human Bone Marrow Mononuclear Cell-Derived Differentiation System.

The Genotype Combination of the P2Y12 Gene Might Confer Greater Risk for Coronary Artery Disease.

Enhancing Effect of Collagen Receptor Polymorphisms on In Vitro Platelet Reactivity to Aspirin in Healthy Subjects.

Identification of ADRA2A Polymorphisms Related to Shear-Mediated Platelet Function by the PFA-100® System.

The Genotypic Combination of Homozygous Carriers of Both H1 Haplotype and 34C Shows a Significantly Lower Responsiveness to ADP-Induced Platelet Aggregation Than Others in Healthy Volunteers.

Ultrastructural Evidences of Caspase-Dependent Platelet Generation in ES Cell-Differentiation System.

Identification of novel mutations in ADAMTS13 in an adult patient with congenital thrombotic thrombocytopenic purpura

Functional phenotype of phosphoinositide 3-kinase p85α-null platelets characterized by an impaired response to GP VI stimulation

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American Society of Hematology

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