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Journal Articles

Multidimensional Analysis of Relapsed Bone Marrow Reveals Cold Immune Microenvironment Post-TMLI in Acute Leukemia Transplant Patients

Free
Srideshikan Sargur Madabushi, Ji Eun Lim, Yu-Lin SU, Paresh Vishwasrao, Dongyun Yang, James F. Sanchez, Sally Mokhtari, Amandeep Salhotra, Xiwei Wu, Haiqing Lee, Savita Dandapani, Ryotaro Nakamura, Raju Pillai, Marcin Kortylewski, Jeffrey Wong, MHD Monzr M. Al Malki, Anthony S. Stein, Susanta Hui
Journal: Blood
Blood (2024) 144 (Supplement 1): 775.
https://doi.org/10.1182/blood-2024-211180
Published: 2024
Journal Articles

Phase III Randomized COMMODORE 1 Trial: 2-Year Safety and Efficacy of Crovalimab in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) Who Switched from Eculizumab

Free
Phillip Scheinberg, Diego Villa Cle, Berangere Devalet, Valentina Giai, Cristina Barrenetxea Lekue, Hsuan-Yu Lin, Zsolt Nagy, Jun-ichi Nishimura, Jens Panse, Agnieszka Piekarska, Jörg Schubert, Kazutaka Sunami, Mustafa Yenerel, Anita Appius, Brittany Gentile, Shino Iwase, Himika Patel, Sasha Sreckovic, Austin G. Kulasekararaj
Journal: Blood
Blood (2024) 144 (Supplement 1): 1313.
https://doi.org/10.1182/blood-2024-200745
Published: 2024
Journal Articles

Pulmonary Dysfunction in Patients with Transfusion-Dependent Thalassemia

Free
Xiao Liang, Gaohui Yang, Lingling Shi, Lianjin Liu, Zhenbin Wei, Yumei Huang, Jing Bai, Yi Liang, Lingyuan Pan, Zhaoping Gan, Yu Lin, Yibin Yao, Ying Tang, Huicheng Huang, Xuemei Zhou, Qifa Liu, Yongrong Lai, Rongrong Liu
Journal: Blood
Blood (2024) 144 (Supplement 1): 1096.
https://doi.org/10.1182/blood-2024-204971
Published: 2024
Journal Articles

Discovery of the Unique GMP-Grade iPSC Clones That Give Rise to Functional, High Purity, Matured CD8 Alpha Beta T or Gamma Delta T with Exponential Expansion Capacity

Free
Ying-Tsen Tung, Chih-Lung Chen, Annie Yi-Ting Lai, Chien-Yu Hsu, Chien-Hsi Chen, Po-Fan Chu, Lin-Yu Liao, Tzu-Chien Kuo, Chieh-Teng Cheng, Chun-Yu Lin, Wan-Chen Tsai, Wei-Ting Chen, Darien Zhing Herr Chan, Hsin-Hua Cho, Cheng-Kai Wang, Yo-Chuen Lin, Jin-Yi Lu, Lee-Yieng Lim, Jhang-Sian Yu, Ming-Chin Ko, Chia-Hung Lin, Yi-Han Dai, I-Ting Chen, Fang-Pei Chang, Shao-Ju Weng, Ting-Yi Wu, Yuan-Yu Hsia, Fu-Fei Hsu, Lillian Yi-Ting Lai, Shiou-Ling Jian, Shih-Wen Huang, Yu-Chih Peng, Ke-Hsun Hsu, Liang-Yi Chen, Ji-Kuan Wang, Yao-Yu Chen, Chih-Kai Yin, Yi-Hung Ou, Min-Ren Chiang, Wen-Hao Wang, Tsung-Hao Yeh, Xiaming Peng, Yang Shi, Pei Zhang, Ya-Chu Yu, Yun Gao, Yen-Hsien Lee, Pei-Chun Wu, Ta-Hsun Liao, De-Kuan Chang, Lien-Szu Wu, Jen-Chih Chi, Ching-Ying Huang, Alex Shih-Min Huang
Journal: Blood
Blood (2024) 144 (Supplement 1): 7195.
https://doi.org/10.1182/blood-2024-203106
Published: 2024
Journal Articles

Characteristics and Long-Term Efficacy of 25 Patients with Paroxysmal Nocturnal Hemoglobinuria Treated with Eculizumab or Ravulizumab in Taiwan

Free
Hsing-Yu Lin, Yu-Wen Chen, Ta-Chuan Yu, Feng-Ming Tien, Chien-Chin Lin, Sheng-Chieh Chou, Shang-Ju Wu, Bor-Sheng Ko, Yung-Li Yang, Ming Yao, Woei Tsay, Hwei-Fang Tien, Hsin-An Hou, Wen-Chien Chou
Journal: Blood
Blood (2024) 144 (Supplement 1): 5672.
https://doi.org/10.1182/blood-2024-199918
Published: 2024
Journal Articles

iPSC-Derived CAR-Gamma Delta T with Novel Combinatorial KO Demonstrated Extended Longevity and Profound Anti-Tumor Efficacy without Cytokine Support in Preclinical Studies

Free
Jhang-Sian Yu, Chia-Hung Lin, Ying-Tsen Tung, Fang-Pei Chang, Edward Po-Fan Chu, Shiou-Ling Jian, Fu-Fei Hsu, Ming-Chin Ko, Yi-Han Dai, Chieh-Teng Cheng, Tzu-Chien Kuo, I-Ting Chen, Ting-Yi Wu, Jin-Yi Lu, Ke-Hsun Hsu, Wei-Ting Chen, Darien Zhing Herr Chan, Yi-Ting Lai, Shao-Ju Weng, Liang-Yi Chen, Yuan-Yu Hsia, Yi-Hung Ou, Yo-Chuen Lin, Shih-Wen Huang, Yu-Chih Peng, Chien-Hsi Chen, Chien-Yu Hsu, Yi-Ting Lai, Chih-Lung Chen, Chun-Yu Lin, Lin-Yu Liao, Wan-Chen Tsai, Hsin-Hua Cho, Cheng-Kai Wang, Lee-Yieng Lim, Ji-Kuan Wang, Yao-Yu Chen, Chih-Kai Yin, Wen-Hao Wang, Tsung-Hao Yeh, Min-Ren Chiang, Ruyue Ji, Jen-Chih Chi, Lien-Szu Wu, Jennifer Huang, De-Kuan Chang, Alex Shih-Min Huang
Journal: Blood
Blood (2024) 144 (Supplement 1): 4790.
https://doi.org/10.1182/blood-2024-205086
Published: 2024
Journal Articles

Treatment with GT1708F, an Oral Smoothened Inhibitor, in Patients with Myeloid Malignancies: A Phase I Study

Free
Jie Jin, Junyuan Qi, Weihua Zhao, Huafeng Wang, Lin Song, Yu Lin, Youzhi Tong, Xiang Ni, Min Dong, Xiaohan He
Journal: Blood
Blood (2023) 142 (Supplement 1): 5964.
https://doi.org/10.1182/blood-2023-180494
Published: 2023
Journal Articles

Clinical Characteristics and Prognosis of Acute Myeloid Leukemia Patients with Protein Tyrosine Phosphatase Non-Receptor Type 11 Gene Mutation

Free
Weihua Zhao, Rui Huang, Yiting Zhang, Yu Lin, Ruli Pang, Zhi Yang
Journal: Blood
Blood (2023) 142 (Supplement 1): 5863.
https://doi.org/10.1182/blood-2023-184840
Published: 2023
Journal Articles

Prevention of acute GVHD using an orthogonal IL-2/IL-2Rβ system to selectively expand regulatory T cells in vivo

Free
Teresa L. Ramos, Sara Bolivar-Wagers, Sujeong Jin, Govindarajan Thangavelu, Federico Simonetta, Po-Yu Lin, Toshihito Hirai, Asim Saha, Brent Koehn, Leon L. Su, Lora K. Picton, Jeanette Baker, Juliane K. Lohmeyer, Megan Riddle, Cindy Eide, Jakub Tolar, Angela Panoskaltsis-Mortari, John E. Wagner, K. Christopher Garcia, Robert S. Negrin, Bruce R. Blazar
Journal: Blood
Blood (2023) 141 (11): 1337–1352.
https://doi.org/10.1182/blood.2022018440
Published: 2023
Includes: Supplemental data
Journal Articles

MEK Inhibition in CAR-T Cells Prevents Exhaustion and Terminal Differentiation Via Downregulating C-Fos and JunB

Free
Xiujian Wang, Xiao Tao, Pengjie Chen, Penglei Jiang, Cong Wei, Wenxiao Li, Hao Zhang, Zuyu Liang, Hefeng Chang, Xinyi Lai, Yihan Pan, Lijuan Ding, Jiazhen Cui, Mi Shao, Xinyi Teng, Jieping Wei, Delin Kong, Xiaohui Si, Yingli Han, Huarui Fu, Yu Lin, Tianning Gu, Jian Yu, Yongxian Hu, Pengxu Qian, He Huang
Journal: Blood
Blood (2022) 140 (Supplement 1): 626–627.
https://doi.org/10.1182/blood-2022-158646
Published: 2022
Journal Articles

Safety and Effectiveness of Ruxolitinib in Real-World Patients with Myelofibrosis: A 2-Year Observational Study from Taiwan

Free
Ming-Chung Kuo, Chien-Chin Lin, Hsuan-Yu Lin, Jyh-Pyng Gau, Ming-Chung Wang, Ming-Chih Chang, Tsung-Chih Chen, Shih-Peng Yeh, Yeu-Chin Chen, Sr., Cih-En Huang, I-Ju Chiang, Chu-Han Chung, Yee-Ming Lee, Fan-Chen Ku, Cheng-Shyong Chang
Journal: Blood
Blood (2022) 140 (Supplement 1): 9709–9710.
https://doi.org/10.1182/blood-2022-156146
Published: 2022
Journal Articles

C/EBPα-p30 Confers AML Cell Susceptibility to the Terminal Unfolded Protein Response and Resistance to Venetoclax By Activating DDIT3 Transcription

Free
Mengbao Du, Mowang Wang, Meng Liu, Shan Fu, Yu Lin, Jian Yu, Xiaohong Yu, He Huang, Haowen Xiao, Limengmeng Wang
Journal: Blood
Blood (2022) 140 (Supplement 1): 3077–3079.
https://doi.org/10.1182/blood-2022-166249
Published: 2022
Journal Articles

Prevention of Acute Graft-Versus-Host Disease Using an Engineered Mouse Orthogonal IL-2/IL-2Rβ Regulatory T Cells

Free
Teresa Lopes Ramos, Sara B. Wagers, Po-Yu Lin, Toshihito Hirai, Leon Su, Lora Picton, Jeanette Baker, Juliane Lohmeyer, Melissa Mavers, Christopher Garcia, Bruce R. Blazar, Robert S. Negrin
Journal: Blood
Blood (2021) 138 (Supplement 1): 1688.
https://doi.org/10.1182/blood-2021-154123
Published: 2021
Journal Articles

Engineering Human Invariant Natural Killer T (iNKT) Cells to Overexpress Immunomodulatory Cytokines

Free
Melissa Mavers, Derek Hollingsworth, Chaiyaporn Boonchalermvichian, Jeffrey Liu, Jeanette Baker, Teresa Lopes Ramos, Juliane K. Lohmeyer, Po-Yu Lin, Maria Grazia Roncarolo, Robert S. Negrin
Journal: Blood
Blood (2021) 138 (Supplement 1): 3888.
https://doi.org/10.1182/blood-2021-153975
Published: 2021
Journal Articles

Invariant natural killer T-cell subsets have diverse graft-versus-host-disease–preventing and antitumor effects

Free
Kristina Maas-Bauer, Juliane K. Lohmeyer, Toshihito Hirai, Teresa Lopes Ramos, Furqan M. Fazal, Ulrike M. Litzenburger, Kathryn E. Yost, Jessica V. Ribado, Neeraja Kambham, Arielle S. Wenokur, Po-Yu Lin, Maite Alvarez, Melissa Mavers, Jeanette Baker, Ami S. Bhatt, Howard Y. Chang, Federico Simonetta, Robert S. Negrin
Journal: Blood
Blood (2021) 138 (10): 858–870.
https://doi.org/10.1182/blood.2021010887
Published: 2021
Includes: Supplemental data
Journal Articles

A composite single-nucleotide polymorphism prediction signature for extranodal natural killer/T-cell lymphoma

Free
Clinical Trials & Observations
Xiao-Peng Tian, Shu-Yun Ma, Ken H. Young, Choon Kiat Ong, Yan-Hui Liu, Zhi-Hua Li, Qiong-Li Zhai, Hui-Qiang Huang, Tong-Yu Lin, Zhi-Ming Li, Zhong-Jun Xia, Li-Ye Zhong, Hui-Lan Rao, Mei Li, Jun Cai, Yu-Chen Zhang, Fen Zhang, Ning Su, Peng-Fei Li, Feng Zhu, Zijun Y. Xu-Monette, Esther Kam Yin Wong, Jeslin Chian Hung Ha, Lay Poh Khoo, Le Ai, Run-Fen Cheng, Jing Quan Lim, Sanjay de Mel, Siok-Bian Ng, Soon Thye Lim, Qing-Qing Cai
Journal: Blood
Blood (2021) 138 (6): 452–463.
https://doi.org/10.1182/blood.2020010637
Published: 2021
Includes: Supplemental data
Journal Articles

Myeloid cell–targeted miR-146a mimic inhibits NF-κB–driven inflammation and leukemia progression in vivo

Free
Yu-Lin Su, Xiuli Wang, Mati Mann, Tomasz P. Adamus, Dongfang Wang, Dayson F. Moreira, Zhuoran Zhang, Ching Ouyang, Xin He, Bin Zhang, Piotr M. Swiderski, Stephen J. Forman, David Baltimore, Ling Li, Guido Marcucci, Mark P. Boldin, Marcin Kortylewski
Journal: Blood
Blood (2020) 135 (3): 167–180.
https://doi.org/10.1182/blood.2019002045
Published: 2020
Includes: Supplemental data
Journal Articles

Targeted Marrow Radiation (TMI) Improves Therapeutic Efficacy of STAT3 Decoy Molecules By Augmenting Its Delivery and Immune Modulation in an AML Mouse Model

Free
Srideshikan Sargur Madabushi, PhD, Darren Zuro, Yu-Lin SU, PhD, Paresh Vishwasrao, MSc, Jamison Brooks, B.S, Liliana E Parra, James F Sanchez, PhD, Jeffrey Wong, MD, Marcin Kortylewski, PhD, Susanta Hui, PhD, DABR.
Journal: Blood
Blood (2019) 134 (Supplement_1): 3929.
https://doi.org/10.1182/blood-2019-127470
Published: 2019
Journal Articles

FLT3-ITD Activates Cytoplasmic Drosha-Dependent Non-Canonical Mechanisms of Mir-155 Biogenesis in Acute Myeloid Leukemia

Free
Le Xuan Truong Nguyen, PhD, Bin Zhang, PhD, Dinh Hoa Hoang, BS, Dandan Zhao, MD, Sergio Branciamore, Davide Maestrini, PhD, Yu-Lin SU, PhD, Sonia Rodriguez, PhD, Flavia Pichiorri, PhD, Steven Rosen, MD, Michael A. Caligiuri, MD, Stephen J. Forman, MD, Ling Li, PhD, Marcin Kortylewski, PhD, Russell Rockne, PhD, Ya-Huei Kuo, PhD, Nadia Carlesso, MD, Guido Marcucci, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2722.
https://doi.org/10.1182/blood-2019-131871
Published: 2019
Journal Articles

Multicentre Genome Wide Association Study Identifies Risk Alleles for Progressive Chronic Lymphocytic Leukaemia

Free
David Allsup, BSc, MBBS, FRCP, FRCPath, PhD, Wei Yu Lin, PhD, Sarah Elizabeth Fordham, PhD BSc, Nicola Sunter, Claire Elstob, PhD, Thahira Rahman, PhD, Elaine Willmore, Colin Shepherd, Gordon Strathdee, BSc, PhD, Timothy Barrow, PhD, Tryfonia Mainou-Fowler, Rachel Piddock, Helen Marr, PhD, Jonathan Wallis, Scott R. Marshall, BSc,MDPhD, Geoffery Summerfield, Andrew Pettitt, FRCPath, PhD, Chris Pepper, BSc, PhD, Christopher Fegan, MB, MD FRCP, FRCPath, Francesco Forconi, MD DM, PhD FRCPath, Martin J.S. Dyer, Sandrine Jayne, PhD, April Sellors, Anna Schuh, PhD, Pauline Robbe, MSc, PhD, David Oscier, Richard S. Houlston, James Bailey, PhDFRCPath,MRCP,MD, Syed Ashar Rais, Alison Bentley, Lynn Cawkwell, Peter Hillmen, MD PhD, Guy Pratt, James M. Allan
Journal: Blood
Blood (2019) 134 (Supplement_1): 1740.
https://doi.org/10.1182/blood-2019-122037
Published: 2019