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Journal Articles

Protection of β2GPI-deficient mice from thrombosis reflects a defect in PAR3-facilitated platelet activation

Paresh P. Kulkarni, Ravi Kumar Alluri, Matthew Godwin, Gabriel L. Forbes, Alona Merkulova, Sylviane Lambert, Aatira Vijay, Maierdan Palihati, Suman Kundu, Young Jun Shim, Kevin Kalonji, Alvin H. Schmaier, Michael Holinstat, Scott J. Cameron, Keith R. McCrae

Blood (2025) 145 (18): 2086–2099.

https://doi.org/10.1182/blood.2024024469

Published: 2025

Includes: Multimedia, Supplemental data

Journal Articles

Programmed Death Ligand 1 Is Released in Platelet-Derived Extracellular Vesicles

Anne K. Hubben, Young Jun Shim, Suman Kundu, Scott J. Cameron, Keith R. McCrae

Blood (2022) 140 (Supplement 1): 11208–11209.

https://doi.org/10.1182/blood-2022-170261

Published: 2022

Journal Articles

Protection of β2GPI Deficient Mice from Thrombosis May Reflect a Platelet Activation Defect

Ravi Kumar Alluri, Matthew Godwin, Gabriel L Forbes, Aatira Vijay, Suman Kundu, Shadi Swaidani, Alvin H. Schmaier, Scott J Cameron, Keith R. McCrae

Blood (2021) 138 (Supplement 1): 2083.

https://doi.org/10.1182/blood-2021-149755

Published: 2021

Journal Articles

Mice Deficient in ß2-Glycoprotein I Have a Delayed Time to Thrombosis

Ravi Kumar Alluri, PhD, Gabriel L Forbes, Suman Kundu, MBA, Alvin H. Schmaier, MD, Keith R McCrae, MD

Blood (2019) 134 (Supplement_1): 2423.

https://doi.org/10.1182/blood-2019-130521

Published: 2019

Journal Articles

Characterization of Recombinant β2GPI Using Hydrogen-Deuterium Exchange and X-Ray Crystallography

Ravi Kumar Alluri, PhD, Nicholas Arce, Philip Klenotic, Chih Chia Su, PhD, Suman Kundu, MBA, Edward Yu, PhD, Renhao Li, PhD, Keith R McCrae, MD

Blood (2019) 134 (Supplement_1): 1105.

https://doi.org/10.1182/blood-2019-131386

Published: 2019

Journal Articles

Biomarker Assessment of Venous Thromboembolism in Cancer Patients Receiving Checkpoint Blockade

Shadi Swaidani, MD PhD, Joanna Roopkumar, MBBS, MPH, Young Jun-Shim, PhD, Cathy Charles, Slato Paul, Suman Kundu, MBA, Pauline Funchain, MD, Patricia Rayman, Paul G. Pavicic, C. Marcela Diaz-Montero, PhD, Alok A Khorana, MD, Keith R McCrae, MD

Blood (2019) 134 (Supplement_1): 3648.

https://doi.org/10.1182/blood-2019-130911

Published: 2019

Journal Articles

Pomalidomide Reduces Bleeding and Alters Expression of Angiogenesis-Related Proteins in Patients with Hereditary Hemorrhagic Telangiectasia

Shadi Swaidani, MD PhD, Suman Kundu, MBA, Mohamed Samour, MBBS, Bernard Silver, MD, Joseph Parambil, MD, Sonia Thomas, DrPH, Keith R McCrae, MD

Blood (2019) 134 (Supplement_1): 5761.

https://doi.org/10.1182/blood-2019-127344

Published: 2019

Journal Articles

A mechanism for hereditary angioedema with normal C1 inhibitor: an inhibitory regulatory role for the factor XII heavy chain

Ivan Ivanov, Anton Matafonov, Mao-fu Sun, Bassem M. Mohammed, Qiufang Cheng, S. Kent Dickeson, Suman Kundu, Ingrid M. Verhamme, Andras Gruber, Keith McCrae, David Gailani

Blood (2019) 133 (10): 1152–1163.

https://doi.org/10.1182/blood-2018-06-860270

Published: 2019

Includes: Supplemental data

Journal Articles

Exosome Polyphosphate Mediates the Activation of FXII By Cancer Cell-Derived Exosomes

Dewen You, PhD, Suman Kundu, MBA, Alvin H. Schmaier, MD, Alok A. Khorana, MD, Keith R. McCrae, MD

Blood (2018) 132 (Supplement 1): 3800.

https://doi.org/10.1182/blood-2018-99-117308

Published: 2018

Journal Articles

Expression of Recombinant β2GPI and Site-Directed Mutants Provides Insight into the Pathogenesis of Antiphospholipid Syndrome

Ravi Kumar Alluri, PhD, Suman Kundu, MBA, Jack Su, PhD, Sekhar Kambakam, Edward Yu, PhD, Keith R. McCrae, MD

Blood (2018) 132 (Supplement 1): 1226.

https://doi.org/10.1182/blood-2018-99-117665

Published: 2018

Journal Articles

Comparison of FXII Activation in Human Plasma By Extracellular Vesicles from Cancer Cells Versus Non-Transformed Cells

Dewen You, PhD, Victor Chatterjee, MD, Suman Kundu, MBA, Mohamed Samour, MBBS, Alvin H. Schmaier, MD, Alok A. Khorana, MD, Keith McCrae, MD

Blood (2017) 130 (Supplement 1): 3705.

https://doi.org/10.1182/blood.V130.Suppl_1.3705.3705

Published: 2017

Journal Articles

A Novel Immunoblot Assay to Detect Contact Activation in Patients with Cancer

Dewen You, PhD, Victor Chatterjee, MD, Mohamed Samour, MBBS, Suman Kundu, MBA, Alvin H. Schmaier, MD, Alok A. Khorana, MD, Keith McCrae, MD

Blood (2017) 130 (Supplement 1): 2385.

https://doi.org/10.1182/blood.V130.Suppl_1.2385.2385

Published: 2017

Journal Articles

Cancer Cell-Derived Extracellular Vesicles Are Prothrombotic in an in-Vitro Vessel Model

Victor Chatterjee, MD, Mohamed Samour, MBBS, Dewen You, PhD, Suman Kundu, MBA, Alok A. Khorana, MD, Keith McCrae, MD

Blood (2017) 130 (Supplement 1): 2308.

https://doi.org/10.1182/blood.V130.Suppl_1.2308.2308

Published: 2017

Journal Articles

Recombinant β2-Glycoprotein I (β2GPI) Produced Using a Novel Lentiviral Approach Functions at Least As Well As Plasma-Derived β2GPI in Detection of Anti-β2GPI Antibodies

Mohamed Samour, MBBS, Shruti Chaturvedi, MBBS, Sergei Merkulov, PhD, Caner Saygin, MD, Heesun J Rogers, MD PhD, Suman Kundu, MS, MBA, Keith R. McCrae, MD

Blood (2016) 128 (22): 2596.

https://doi.org/10.1182/blood.V128.22.2596.2596

Published: 2016

Journal Articles

Pomalidomide in Hereditary Hemorrhagic Telangiectasia: Interim Results of a Phase I Study

Mohamed Samour, MBBS, Caner Saygin, MD, Rashid Abdallah, RN, Suman Kundu, MS, MBA, Keith R. McCrae, MD

Blood (2016) 128 (22): 210.

https://doi.org/10.1182/blood.V128.22.210.210

Published: 2016

Journal Articles

Anti-ß2GPI Antibodies Induce Oxidative and Nitrative Stress in Endothelial Cells through Activation of Discrete Nox Isoforms and eNOS Uncoupling

Ravi Kumar Alluri, PhD, Meifang Wu, MD, Suman Kundu, MS, MBA, Keith R. McCrae, MD

Blood (2016) 128 (22): 720.

https://doi.org/10.1182/blood.V128.22.720.720

Published: 2016

Journal Articles

NADPH Oxidase Activation and Endothelial Nitric Oxide Synthase Uncoupling Contribute to Endothelial Dysfunction in Antiphospholipid Syndrome

Meifang Wu, MD, Suman Kundu, MS, MBA, Keith R. McCrae, MD

Blood (2015) 126 (23): 4639.

https://doi.org/10.1182/blood.V126.23.4639.4639

Published: 2015

Journal Articles

The SRC Kinase Family Member Lymphocyte Specific Kinase (p56 Lck ) Regulates Endothelial Cell Proliferation and Survival

Venkaiah Betapudi, PhD, Sergei M. Merkoulov, PhD, Suman Kundu, MBA, Ou Ji, MD, Meifang Wu, MD, Keith R. McCrae, MD

Blood (2014) 124 (21): 1445.

https://doi.org/10.1182/blood.V124.21.1445.1445

Published: 2014

Journal Articles

Therapy with Bevacizumab Is Associated with Reduced Expression of KLF2 in Peripheral Blood Mononuclear Cells: A Potential Prothrombotic Mechanism

Suman Kundu, MBA, Micheal Mawhorter, BS, Sergei M. Merkoulov, PhD, Keith R. McCrae, MD, Alok A. Khorana, MD

Blood (2014) 124 (21): 4254.

https://doi.org/10.1182/blood.V124.21.4254.4254

Published: 2014

Journal Articles

A Novel Mechanism of Cellular Activation Mediated By Antiphospholipid Antibody-Induced Extracellular Vesicles

Meifang Wu, MD, Suman Kundu, MBA, Venkaiah Betapudi, PhD, Keith R. McCrae, MD

Blood (2014) 124 (21): 100.

https://doi.org/10.1182/blood.V124.21.100.100

Published: 2014

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Protection of β2GPI-deficient mice from thrombosis reflects a defect in PAR3-facilitated platelet activation

Programmed Death Ligand 1 Is Released in Platelet-Derived Extracellular Vesicles

Protection of β2GPI Deficient Mice from Thrombosis May Reflect a Platelet Activation Defect

Mice Deficient in ß2-Glycoprotein I Have a Delayed Time to Thrombosis

Characterization of Recombinant β2GPI Using Hydrogen-Deuterium Exchange and X-Ray Crystallography

Biomarker Assessment of Venous Thromboembolism in Cancer Patients Receiving Checkpoint Blockade

Pomalidomide Reduces Bleeding and Alters Expression of Angiogenesis-Related Proteins in Patients with Hereditary Hemorrhagic Telangiectasia

A mechanism for hereditary angioedema with normal C1 inhibitor: an inhibitory regulatory role for the factor XII heavy chain

Exosome Polyphosphate Mediates the Activation of FXII By Cancer Cell-Derived Exosomes

Expression of Recombinant β2GPI and Site-Directed Mutants Provides Insight into the Pathogenesis of Antiphospholipid Syndrome

Comparison of FXII Activation in Human Plasma By Extracellular Vesicles from Cancer Cells Versus Non-Transformed Cells

A Novel Immunoblot Assay to Detect Contact Activation in Patients with Cancer

Cancer Cell-Derived Extracellular Vesicles Are Prothrombotic in an in-Vitro Vessel Model

Recombinant β2-Glycoprotein I (β2GPI) Produced Using a Novel Lentiviral Approach Functions at Least As Well As Plasma-Derived β2GPI in Detection of Anti-β2GPI Antibodies

Pomalidomide in Hereditary Hemorrhagic Telangiectasia: Interim Results of a Phase I Study

Anti-ß2GPI Antibodies Induce Oxidative and Nitrative Stress in Endothelial Cells through Activation of Discrete Nox Isoforms and eNOS Uncoupling

NADPH Oxidase Activation and Endothelial Nitric Oxide Synthase Uncoupling Contribute to Endothelial Dysfunction in Antiphospholipid Syndrome

The SRC Kinase Family Member Lymphocyte Specific Kinase (p56 Lck ) Regulates Endothelial Cell Proliferation and Survival

Therapy with Bevacizumab Is Associated with Reduced Expression of KLF2 in Peripheral Blood Mononuclear Cells: A Potential Prothrombotic Mechanism

A Novel Mechanism of Cellular Activation Mediated By Antiphospholipid Antibody-Induced Extracellular Vesicles

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