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Journal Articles

Association of Gene Expression Patterns in Bone Marrow Cells with Likelihood of Treatment Free Remission after TKI Discontinuation

Jianbo He, MD, Sahee Park, Soo Young Choi, David Crossman, Bin Zhang, PhD, Puneet Agarwal, PhD, Andrew Zhang, Su Chu, MD, Dong-Wook Kim, MD PhD, Ravi Bhatia, MD

Blood (2018) 132 (Supplement 1): 1721.

https://doi.org/10.1182/blood-2018-99-114137

Published: 2018

Journal Articles

Hoxa9 and Hoxa10 Induce CML Myeloid Blast Crisis Development through Activation of Myb Expression

Vijay Negi, PhD, Bandana Ajay Vishwakarma, BSc, MSc, PhD, Su Chu, MD, Kevin Oakley, Yufen Han, Ravi Bhatia, MD, Yang Du, PhD

Blood (2017) 130 (Supplement 1): 2865.

https://doi.org/10.1182/blood.V130.Suppl_1.2865.2865

Published: 2017

Journal Articles

Inhibition of interleukin-1 signaling enhances elimination of tyrosine kinase inhibitor–treated CML stem cells

Bin Zhang, Su Chu, Puneet Agarwal, Victoria L. Campbell, Lisa Hopcroft, Heather G. Jørgensen, Allen Lin, Karl Gaal, Tessa L. Holyoake, Ravi Bhatia

Blood (2016) 128 (23): 2671–2682.

https://doi.org/10.1182/blood-2015-11-679928

Published: 2016

Journal Articles

Enhanced Targeting of FLT3-ITD+AML Stem Cells through Combined Inhibition of SIRT1 and Autophagic Flux

Su Chu, MD, Yao-Te Hsieh, PhD, Marcus JGW Ladds, Sonia Lane, PhD, Ravi Bhatia, MD

Blood (2016) 128 (22): 31.

https://doi.org/10.1182/blood.V128.22.31.31

Published: 2016

Journal Articles

MicroRNA-486 regulates normal erythropoiesis and enhances growth and modulates drug response in CML progenitors

Li-Sheng Wang, Ling Li, Liang Li, Su Chu, Keh-Dong Shiang, Min Li, Hui-Yan Sun, Jun Xu, Feng-Jun Xiao, Guihua Sun, John J. Rossi, YinWei Ho, Ravi Bhatia

Blood (2015) 125 (8): 1302–1313.

https://doi.org/10.1182/blood-2014-06-581926

Published: 2015

Includes: Supplemental data

Journal Articles

Effective and Selective Elimination of CML Stem Cells Using Novel Ethacrynic Acid Derivatives

Su Chu, MD, YinWei Ho, Guisen Zhao, Tessa L. Holyoake, MD PhD, Samuel Waxman, MD, Yongkui Jing, PhD, Ravi Bhatia, MD

Blood (2014) 124 (21): 4508.

https://doi.org/10.1182/blood.V124.21.4508.4508

Published: 2014

Journal Articles

Pharmacological Inhibition Of The SIRT1 Deacetylase With The Small Molecule Inhibitor Tenovin-6 Enhances Ablation Of FLT3-ITD+ LSC In Combination With TKI Treatment

Ling Li, PhD, Tereza Osdal, MSc, YinWei Ho, MA, Tinisha McDonald, Sookhee Chun, Su Chu, MD, Allen Lin, Cedric Dos Santos, Ph.D, Mihaela Lucia Popa, VMD, Bjorn T Gjertsen, MD PhD, Wenyong Chen, PhD, Sonia Lain, Emmet McCormack, PhD, Ravi Bhatia, MD

Blood (2013) 122 (21): 2685.

https://doi.org/10.1182/blood.V122.21.2685.2685

Published: 2013

Journal Articles

MJ05, a Novel p53 Activating Compound, Effectively and Selectively Eliminates Human CML Stem/Progenitor Cells

Su Chu, MD, Catherine Drummond, Ling Li, PhD, YinWei Ho, MA, Sonia Lain, Ravi Bhatia, MD

Blood (2013) 122 (21): 1464.

https://doi.org/10.1182/blood.V122.21.1464.1464

Published: 2013

Journal Articles

Selective Targeting of CML Progenitor/Stem Cells by the Class 1 Histone Deacetylase (HDAC) Inhibitor MS275 in Combination with Imatinib.

Su Chu, MD, YinWei Ho, Ravi Bhatia, MD

Blood (2012) 120 (21): 2791.

https://doi.org/10.1182/blood.V120.21.2791.2791

Published: 2012

Journal Articles

Setbp1 promotes the self-renewal of murine myeloid progenitors via activation of Hoxa9 and Hoxa10

Kevin Oakley, Yufen Han, Bandana A. Vishwakarma, Su Chu, Ravi Bhatia, Kristbjorn O. Gudmundsson, Jonathan Keller, Xiongfong Chen, Vasyl Vasko, Nancy A. Jenkins, Neal G. Copeland, Yang Du

Blood (2012) 119 (25): 6099–6108.

https://doi.org/10.1182/blood-2011-10-388710

Published: 2012

Includes: Supplemental data

Journal Articles

Role of MicroRNA-486-5p Overexpression In CML CD34+ Cells In Modulating BCR-ABL Mediated Hematopoietic Stem/Progenitor Cell Transformation and Imatinib Sensitivity

Li-Sheng Wang, Ling Li, PhD, Liang Li, PhD, Keh-Dong Shiang, Min Li, PhD, Su Chu, MD, Ravi Bhatia, MD

Blood (2011) 118 (21): 1667.

https://doi.org/10.1182/blood.V118.21.1667.1667

Published: 2011

Journal Articles

RNAi-Mediated Inhibition of Mcl-1 Expression Enhances Apoptosis in Imatinib-Treated CML Progenitors

Su Chu, MD, Ravi Bhatia, MD

Blood (2011) 118 (21): 1669.

https://doi.org/10.1182/blood.V118.21.1669.1669

Published: 2011

Journal Articles

Persistence of leukemia stem cells in chronic myelogenous leukemia patients in prolonged remission with imatinib treatment

Su Chu, Tinisha McDonald, Allen Lin, Sujata Chakraborty, Qin Huang, David S. Snyder, Ravi Bhatia

Blood (2011) 118 (20): 5565–5572.

https://doi.org/10.1182/blood-2010-12-327437

Published: 2011

Includes: Supplemental data

Journal Articles

An RNA Interference Screen Reveals a Critical Role for Mcl-1 In Survival of CML Progenitor Cells.

Su Chu, MD, Ravi Bhatia, MD

Blood (2010) 116 (21): 1203.

https://doi.org/10.1182/blood.V116.21.1203.1203

Published: 2010

Journal Articles

Bortezomib induces apoptosis in primitive chronic myeloid leukemia cells including LTC-IC and NOD/SCID repopulating cells

Nicholas B. Heaney, Francesca Pellicano, Bin Zhang, Lisa Crawford, Su Chu, Syed M. A. Kazmi, Elaine K. Allan, Heather G. Jorgensen, Alexandra E. Irvine, Ravi Bhatia, Tessa L. Holyoake

Blood (2010) 115 (11): 2241–2250.

https://doi.org/10.1182/blood-2008-06-164582

Published: 2010

Includes: Supplemental data

Journal Articles

Effective Targeting of Quiescent CML Stem Cells by Histone Deacetylase Inhibitors in Combination with Imatinib Mesylate.

Bin Zhang, MD, PhD, Adam Campbell Strauss, Su Chu, MD, Yin Wei Ho, David S. Snyder, MD, Claudia Huettner, PhD, Lenny Shultz, Tessa L Holyoake, PhD, Ravi Bhatia, MD

Blood (2009) 114 (22): 190.

https://doi.org/10.1182/blood.V114.22.190.190

Published: 2009

Journal Articles

Persistence of Leukemia Stem Cells in Chronic Myelogenous Leukemia Patients in Complete Cytogenetic Remission on Imatinib Treatment for 5 Years

Su Chu, MD, Allen Lin, Tinisha McDonald, David S. Snyder, MD, Stephen J. Forman, MD, Ravi Bhatia, MD

Blood (2008) 112 (11): 194.

https://doi.org/10.1182/blood.V112.11.194.194

Published: 2008

Journal Articles

Effect of Inhibition of Grb2 Expression on BCR-ABL Mediated Transformation of Primary Human Hematopoietic Cells.

Hardik Modi, MS, Liang Li, PhD, Su Chu, MD, Ravi Bhatia, MD

Blood (2007) 110 (11): 1020.

https://doi.org/10.1182/blood.V110.11.1020.1020

Published: 2007

Journal Articles

Effective Induction of Apoptosis in Chronic Myeloid Leukemia CD34+ Cells by the Histone Deacetylase Inhibitor LAQ824 in Combination with Imatinib.

Adam C. Strauss, BA, Su Chu, M.D., Tessa Holyoake, M.D., Ravi Bhatia, M.D.

Blood (2007) 110 (11): 1031.

https://doi.org/10.1182/blood.V110.11.1031.1031

Published: 2007

Journal Articles

Enhanced Phosphorylation and Altered Localization Lead to Impairment of p27 kip Activity in CML Progenitor Cells Despite Enhanced Protein Translation and Expression.

Su Chu, MD, Tinisha McDonald, Ravi Bhatia, MD

Blood (2007) 110 (11): 999.

https://doi.org/10.1182/blood.V110.11.999.999

Published: 2007

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Association of Gene Expression Patterns in Bone Marrow Cells with Likelihood of Treatment Free Remission after TKI Discontinuation

Hoxa9 and Hoxa10 Induce CML Myeloid Blast Crisis Development through Activation of Myb Expression

Inhibition of interleukin-1 signaling enhances elimination of tyrosine kinase inhibitor–treated CML stem cells

Enhanced Targeting of FLT3-ITD+AML Stem Cells through Combined Inhibition of SIRT1 and Autophagic Flux

MicroRNA-486 regulates normal erythropoiesis and enhances growth and modulates drug response in CML progenitors

Effective and Selective Elimination of CML Stem Cells Using Novel Ethacrynic Acid Derivatives

Pharmacological Inhibition Of The SIRT1 Deacetylase With The Small Molecule Inhibitor Tenovin-6 Enhances Ablation Of FLT3-ITD+ LSC In Combination With TKI Treatment

MJ05, a Novel p53 Activating Compound, Effectively and Selectively Eliminates Human CML Stem/Progenitor Cells

Selective Targeting of CML Progenitor/Stem Cells by the Class 1 Histone Deacetylase (HDAC) Inhibitor MS275 in Combination with Imatinib.

Setbp1 promotes the self-renewal of murine myeloid progenitors via activation of Hoxa9 and Hoxa10

Role of MicroRNA-486-5p Overexpression In CML CD34+ Cells In Modulating BCR-ABL Mediated Hematopoietic Stem/Progenitor Cell Transformation and Imatinib Sensitivity

RNAi-Mediated Inhibition of Mcl-1 Expression Enhances Apoptosis in Imatinib-Treated CML Progenitors

Persistence of leukemia stem cells in chronic myelogenous leukemia patients in prolonged remission with imatinib treatment

An RNA Interference Screen Reveals a Critical Role for Mcl-1 In Survival of CML Progenitor Cells.

Bortezomib induces apoptosis in primitive chronic myeloid leukemia cells including LTC-IC and NOD/SCID repopulating cells

Effective Targeting of Quiescent CML Stem Cells by Histone Deacetylase Inhibitors in Combination with Imatinib Mesylate.

Persistence of Leukemia Stem Cells in Chronic Myelogenous Leukemia Patients in Complete Cytogenetic Remission on Imatinib Treatment for 5 Years

Effect of Inhibition of Grb2 Expression on BCR-ABL Mediated Transformation of Primary Human Hematopoietic Cells.

Effective Induction of Apoptosis in Chronic Myeloid Leukemia CD34+ Cells by the Histone Deacetylase Inhibitor LAQ824 in Combination with Imatinib.

Enhanced Phosphorylation and Altered Localization Lead to Impairment of p27 kip Activity in CML Progenitor Cells Despite Enhanced Protein Translation and Expression.

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American Society of Hematology

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